Cause of death in patients with dementia disorders.

abstract：BACKGROUND AND PURPOSE:Growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis abnormalities in multiple sclerosis (MS) suggest their role in its pathogenesis. Interferon β (IFN-β) efficacy could be mediated also by an increase of IGF-1 levels. A 2-year longitudinal study was performed to estimate the prevalence ...

journal_title：European journal of neurology

authors： Lanzillo R,Di Somma C,Quarantelli M,Carotenuto A,Pivonello C,Moccia M,Cianflone A,Marsili A,Puorro G,Saccà F,Russo CV,De Luca Picione C,Ausiello F,Colao A,Brescia Morra V

更新日期：2017-02-01 00:00:00

abstract：:We here present the case of a patient with a sleep disturbance attributed to the exploding head syndrome, recently redefined as 'episodic cranial sensory shock'. The patient, who suffered with concomitant migraine, was treated for headache prevention with daily single-pulse transcranial magnetic stimulation. Following...

journal_title：European journal of neurology

authors： Puledda F,Moreno-Ajona D,Goadsby PJ

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Randomized trials and meta-analyses indicate positive effects of stroke unit (SU) care on survival and dependency of patients with stroke. However, data on the advantages of SU in 'real-world' settings are limited. We prospectively assessed, in a large University Hospital, the effect of SU versus other conve...

journal_title：European journal of neurology

authors： Di Carlo A,Lamassa M,Wellwood I,Bovis F,Baldereschi M,Nencini P,Poggesi A,Cramaro A,Pescini F,Lucente G,Wolfe CD,Inzitari D,European Registers of Stroke (EROS) Project.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:  A low ankle-brachial index (ABI) is predictive of peripheral arterial disease (PAD). For unknown reasons, patients with PAD demonstrate higher vascular mortality during follow-up than do those without. Initial stroke severity is a strong predictor of long-term outcome and may be different between patients ...

journal_title：European journal of neurology

authors： Lee DH,Kim J,Lee HS,Cha MJ,Kim YD,Nam HS,Nam CM,Heo JH

更新日期：2012-06-01 00:00:00

abstract：:Digital subtraction angiography (DSA) is considered to be the 'gold standard' for confirmation of severe (70-99%) stenoses of internal carotid arteries (ICAs). However, it is associated with a risk of complications. The aim of this study was to assess the accuracy of ultrasonography (US), computed tomographic angiogra...

journal_title：European journal of neurology

authors： Herzig R,Burval S,Krupka B,Vlachová I,Urbánek K,Mares J

更新日期：2004-11-01 00:00:00

abstract：:Serial single fiber electromyography (SFEMG) examinations of orbicularis oculi muscle in patients with blepharospasm or hemifacial spasm treated with botulinum toxin injections were performed. The aim of the study was to evaluate the impairment of neuromuscular transmission, to follow reinnervation after botulinum tox...

journal_title：European journal of neurology

authors： Bogucki A

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Peripapillary retinal nerve fibre layer (pRNFL) thickness is a strong candidate as a biomarker of axonal degeneration in multiple sclerosis (MS). The aim was to determine a cut-off value of pRNFL thinning rates in relapsing-remitting MS (RRMS) to discriminate between stable and progressing patien...

journal_title：European journal of neurology

authors： Bsteh G,Hegen H,Teuchner B,Berek K,Wurth S,Auer M,Di Pauli F,Deisenhammer F,Berger T

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:We investigated whether the prevalence of primary headaches was higher in patients with primary Sjøgren's syndrome (PSS) than in healthy individuals. METHODS:This retrospective cohort study included 71 patients with PSS (patients) based on the American European Consensus Classification criteria, and 71 age-...

journal_title：European journal of neurology

authors： Tjensvoll AB,Harboe E,Gøransson LG,Beyer MK,Greve OJ,Kvaløy JT,Omdal R

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite recent advances in neurogenetics that have facilitated the identification of a number of dystonia genes, many familial dystonia syndromes remain without known cause. The aim of the study was to identify the cause of autosomal dominant tremulous myoclonus-dystonia in a UK kindred with affe...

journal_title：European journal of neurology

authors： Balint B,Guerreiro R,Carmona S,Dehghani N,Latorre A,Cordivari C,Bhatia KP,Bras J

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Portugal has been identified as one of the countries with a high prevalence of LRRK2-G2019S, considered to be the most frequent known cause of familial and sporadic Parkinson's disease (PD). The aim of this study was to evaluate the prevalence of PD in Portugal using a door-to-door methodology. ...

journal_title：European journal of neurology

authors： Ferreira JJ,Gonçalves N,Valadas A,Januário C,Silva MR,Nogueira L,Vieira JLM,Lima AB

更新日期：2017-05-01 00:00:00

abstract：:Recently, a novel protein-interaction partner of alpha-synuclein, designated synphilin-1, is identified as a constituent of Lewy bodies (LB) in Parkinson's disease (PD) brains. To investigate an involvement of genetic variations of synphilin-1 in development of sporadic PD, a possible single nucleotide polymorphism (S...

journal_title：European journal of neurology

authors： Satoh JI,Kuroda Y

更新日期：2002-01-01 00:00:00

abstract：:We report here a novel point mutation in exon 5 of the Cu/Zn superoxide dismutase (SOD) gene resulting in an amino acid substitution of valine(148) by isoleucine (V148I) in a Japanese family with amyotrophic lateral sclerosis (FALS). In this family, the age at onset was young (28.0 ± 3.8 years old, mean ± SD, n = 4) a...

journal_title：European journal of neurology

authors： Sakuma R,Abe K,Aoki M,Ikeda M,Okita N,Hiwatari M,Sakurai M,Itoyama Y

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Disease-modifying therapies provide new horizons for hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) to slow neuropathic progression. Initiating treatment at the earliest time requires biomarkers reflecting both small- and large-fiber degeneration in carriers. METHODS:This st...

journal_title：European journal of neurology

authors： Chiang MC,Yeh TY,Sung JY,Hsueh HW,Kao YH,Hsueh SJ,Chang KC,Feng FP,Lin YH,Chao CC,Hsieh ST

更新日期：2020-12-28 00:00:00

abstract：:Studies of the cephalic vascular system have markedly contributed towards an understanding of the mechanisms of migraine pain. Whereas cerebral blood flow changes, and thereby changes in the arterioles, correlate poorly with migraine headache, abnormal regulation of the large cranial arteries seems to play a significa...

journal_title：European journal of neurology

authors： Thomsen LL

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticipatory postural adjustments (APAs), prior to step initiation, are bradykinetic in advanced Parkinson's disease (PD) and may be one of the factors associated with 'start hesitation'. However, little is known about APAs in the early stage of PD. In this study, we determined whether body-worn ...

journal_title：European journal of neurology

authors： Mancini M,Zampieri C,Carlson-Kuhta P,Chiari L,Horak FB

更新日期：2009-09-01 00:00:00

abstract：:In visual evoked potential studies, habituation during stimulus repetition with the same stimulus at a constant intensity has been found to be abnormal in migraineurs between attacks. The purpose of this study was to investigate habituation of somatosensory evoked potentials (SEPs) and the effects of migraine on them....

journal_title：European journal of neurology

authors： Ozkul Y,Uckardes A

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The expanded repeat length in ATXN1 negatively correlates with age at onset (AAO) of spinocerebellar ataxia type 1 (SCA1) but can explain only part of it, indicating that other factors affect AAO. Some studies have explored the influence of non-causative CAG repeats on the AAO of SCA patients. Ho...

journal_title：European journal of neurology

authors： Wang P,Chen Z,Peng Y,Cao L,Li X,Wang C,Yang H,Peng H,Shi Y,Zhou X,Li T,Feng L,Wu C,Qiu R,Xia K,Tang B,Jiang H

更新日期：2019-08-01 00:00:00

abstract：:A recently symptomatic carotid artery stenosis carries a high risk of subsequent ischaemic events and thus requires rapid treatment. We investigated the influence of the time delay between the last symptomatic event of a carotid stenosis and subsequent carotid artery stenting (CAS) with respect to the combined 30-day ...

journal_title：European journal of neurology

authors： Gröschel K,Knauth M,Ernemann U,Pilgram SM,Schnaudigel S,Kastrup A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study investigated whether incompleteness of the anterior part of the circle of Willis affects the occurrence of lacunes in the basal ganglia. METHODS:One thousand and seventy-seven healthy individuals examined by magnetic resonance (MR) imaging and MR angiography were divided into eight su...

journal_title：European journal of neurology

authors： Miyazawa N,Shinohara T,Yamagata Z

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately 9000 people in the UK are affected by Huntington's disease (HD). People with HD require ongoing health and social care support. There is a knowledge gap about costs of health and social care use associated with HD in the UK. This paper estimates the economic cost in the UK. METHODS...

journal_title：European journal of neurology

authors： Jones C,Busse M,Quinn L,Dawes H,Drew C,Kelson M,Hood K,Rosser A,Edwards RT

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevation of cardiac troponin (cTn), a sensitive biomarker of myocardial injury, is frequently observed in severe acute neurological disorders. Case reports suggest that cardiac dysfunction may also occur in patients with transient global amnesia (TGA). Until now, no study has systematically asse...

journal_title：European journal of neurology

authors： Erdur H,Siegerink B,Ganeshan R,Audebert HJ,Endres M,Nolte CH,Scheitz JF

更新日期：2019-07-01 00:00:00

abstract：:Since the 1970s, intravenous (IV) phenytoin (PHT) has traditionally been used as second-stage treatment for convulsive status epilepticus (SE) after failure of benzodiazepines. The aim of this review was to critically assess the evidence supporting the use of IV PHT as treatment of convulsive SE in patients of any age...

journal_title：European journal of neurology

authors： Brigo F,Bragazzi NL,Lattanzi S,Nardone R,Trinka E

更新日期：2018-03-01 00:00:00

abstract：:A 45 year-old man presented with a rapid onset of memory impairment Brain computed tomography showed multiple abnormal low density areas in the deep cerebral white matter. Magnetic resonance imaging revealed bilateral thalamic infarcts and extensive thrombosis of the vein of Galen and the straight sinus, which was con...

journal_title：European journal of neurology

authors： Daif AK,Awada A,Rajeh SA,Andeejani A

更新日期：1995-11-01 00:00:00

abstract：:The aim of the study was to use functional transcranial Doppler to investigate the possibility of revealing different activation patterns during healthy subjects' performance of meaningful and meaningless actions. Mean flow velocity (MFV) changes were recorded in middle cerebral arteries (MCAs) of 26 normal subjects d...

journal_title：European journal of neurology

authors： Matteis M,Federico F,Troisi E,Pasqualetti P,Vernieri F,Caltagirone C,Petrosini L,Silvestrini M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Risk-stratification models based on patient and disease characteristics are useful for aiding clinical decisions and for comparing the quality of care between different physicians or hospitals. In addition, prediction of mortality is beneficial for optimizing resource utilization. We evaluated th...

journal_title：European journal of neurology

authors： Peng SY,Chuang YC,Kang TW,Tseng KH

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The burden of multiple sclerosis (MS) includes fatigue, depression and worsening of health-related quality of life (HRQOL). These changes have not been yet measured in neuromyelitis optica (NMO). Our aim was to assess the HRQOL, fatigue and depression in NMO. METHODS:We administered French validated self-qu...

journal_title：European journal of neurology

authors： Chanson JB,Zéphir H,Collongues N,Outteryck O,Blanc F,Fleury M,Vermersch P,de Seze J

更新日期：2011-06-01 00:00:00

abstract：:In approximately 40% of the patients, Parkinson's disease (PD) is complicated by cognitive impairment. The objective of this study was to evaluate the impact of cognitive impairment on disease severity and motor function in idiopathic PD patients. Forty-one PD patients with cognitive impairment (PD-CI) (Mini-Mental St...

journal_title：European journal of neurology

authors： Papapetropoulos S,Ellul J,Polychronopoulos P,Chroni E

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Histamine N-methyltransferase (HNMT) is the main metabolizing enzyme of histamine (a mediator of inflammation implicated in the pathogenesis of multiple sclerosis-MS) in the CNS. We have investigated the possible association between a single nucleotide polymorphism of the HNMT (chromosome 2q22.1), that cause...

journal_title：European journal of neurology

authors： García-Martín E,Martínez C,Benito-León J,Calleja P,Díaz-Sánchez M,Pisa D,Alonso-Navarro H,Ayuso-Peralta L,Torrecilla D,Agúndez JA,Jiménez-Jiménez FJ

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our study aims to evaluate retinal function and neural conduction in post-retinal visual pathways of patients with non-arteritic ischaemic optic neuropathy (NION). METHODS:Twenty patients (mean age: 63.7 +/- 5.96 year) with NION and 20 age-similar control subjects were enrolled. Simultaneous rec...

journal_title：European journal of neurology

authors： Parisi V,Gallinaro G,Ziccardi L,Coppola G

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CACNA1S encodes Cav 1.1, a voltage sensor for muscle excitation-contraction coupling, which activates the ryanodine receptor 1 (RYR1) leading to calcium release from the sarcoplasmic reticulum. CACNA1S mutations cause hypokalemic periodic paralysis, malignant hyperthermia and congenital myopathy....

journal_title：European journal of neurology

authors： Anandan C,Cipriani MA,Laughlin RS,Niu Z,Milone M

更新日期：2018-02-01 00:00:00