Anticipatory postural adjustments prior to step initiation are hypometric in untreated Parkinson's disease: an accelerometer-based approach.

abstract：:Charcot-Marie-Tooth disease (CMT) has been classified into two types: demyelinating forms (CMT1) and axonal forms (CMT2). Mutations in the CMT2A locus have been linked to the KIF1B and the mitofusin 2 (MFN2) genes. Here, we report a German patient with CMT2 with an underlying spontaneous mutation (c.281G-->A) in the M...

journal_title：European journal of neurology

authors： Neusch C,Senderek J,Eggermann T,Elolff E,Bähr M,Schneider-Gold C

更新日期：2007-05-01 00:00:00

abstract：:The aim of this study was to compare the clinically based prevalence of myasthenia gravis (MG) with the prevalence of laboratory-confirmed cases. All patients with a diagnosis of MG living in Estonia as on 1 January 1997 were asked to participate in re-examination. The criteria for laboratory-supported MG were weaknes...

journal_title：European journal of neurology

authors： Oöpik M,Puksa L,Lüüs SM,Kaasik AE,Jakobsen J

更新日期：2008-03-01 00:00:00

abstract：:Most patients with acute disseminated encephalomyelitis (ADEM) recover quickly under corticosteroid treatment and have a favourable long-term prognosis. We report on a young woman with acute onset of an extensive and solitary white-matter lesion in the left hemisphere. Fever, high pleocytosis and elevated protein in c...

journal_title：European journal of neurology

authors： Harloff A,Rauer S,Hofer M,Klisch J,Els T

更新日期：2005-01-01 00:00:00

abstract：:An alanin-9valin (Ala-9Val) polymorphism in the mitochondrial targeting sequence of manganese-containing superoxide dismutase (Mn-SOD) has recently been described. We studied this polymorphism in 72 Swedish patients with sporadic motor neuron diseases (MND) and controls using an oligonucleotide ligation assay. There w...

journal_title：European journal of neurology

authors： Van Landeghem GF,Tabatabaie P,Beckman G,Beckman L,Andersen PM

更新日期：1999-11-01 00:00:00

abstract：:To evaluate prevalence of use and prescribing patterns of antiepileptic drugs (AEDs) in Italian general practice. Primary care data were obtained from the Health Search Database, a longitudinal observational database implemented by the Italian College of General Practitioners (GPs). We selected 465 061 subjects regist...

journal_title：European journal of neurology

authors： Savica R,Beghi E,Mazzaglia G,Innocenti F,Brignoli O,Cricelli C,Caputi AP,Musolino R,Spina E,Trifirò G

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:A Task Force was convened by the EFNS/MDS-ES Scientist Panel on Parkinson's disease (PD) and other movement disorders to systemically review relevant publications on the diagnosis of PD. METHODS:Following the EFNS instruction for the preparation of neurological diagnostic guidelines, recommendation levels h...

journal_title：European journal of neurology

authors： Berardelli A,Wenning GK,Antonini A,Berg D,Bloem BR,Bonifati V,Brooks D,Burn DJ,Colosimo C,Fanciulli A,Ferreira J,Gasser T,Grandas F,Kanovsky P,Kostic V,Kulisevsky J,Oertel W,Poewe W,Reese JP,Relja M,Ruzicka E,Sc

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis abnormalities in multiple sclerosis (MS) suggest their role in its pathogenesis. Interferon β (IFN-β) efficacy could be mediated also by an increase of IGF-1 levels. A 2-year longitudinal study was performed to estimate the prevalence ...

journal_title：European journal of neurology

authors： Lanzillo R,Di Somma C,Quarantelli M,Carotenuto A,Pivonello C,Moccia M,Cianflone A,Marsili A,Puorro G,Saccà F,Russo CV,De Luca Picione C,Ausiello F,Colao A,Brescia Morra V

更新日期：2017-02-01 00:00:00

abstract：:We examined the prevalence and correlates of apathy and irritability in a consecutive series of 101 patients with probable Alzheimer's disease (AD). Based on clinical criteria, 46 (46%) patients had apathy, and 13 (13%) patients had irritability. Apathy was significantly associated with more severe impairments in acti...

journal_title：European journal of neurology

authors： Starkstein SE,Migliorelli R,Manes F,Tesón A,Petracca G,Chemerinski E,Sabe L,Leiguarda R

更新日期：1995-12-01 00:00:00

abstract：:Recently, diagnostic clinical and imaging criteria for primary progressive aphasia (PPA) have been revised by an international consortium (Gorno-Tempini et al. Neurology 2011;76:1006-14). The aim of this study was to validate the specificity of the new imaging criteria and investigate whether different imaging modalit...

journal_title：European journal of neurology

authors： Bisenius S,Neumann J,Schroeter ML

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Randomized trials and meta-analyses indicate positive effects of stroke unit (SU) care on survival and dependency of patients with stroke. However, data on the advantages of SU in 'real-world' settings are limited. We prospectively assessed, in a large University Hospital, the effect of SU versus other conve...

journal_title：European journal of neurology

authors： Di Carlo A,Lamassa M,Wellwood I,Bovis F,Baldereschi M,Nencini P,Poggesi A,Cramaro A,Pescini F,Lucente G,Wolfe CD,Inzitari D,European Registers of Stroke (EROS) Project.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Isolated rapid eye movement sleep behaviour disorder (iRBD) is a parasomnia, recently recognized as a risk factor for progression to Parkinson's disease, dementia with Lewy body and multiple system atrophy. Biomarker studies in iRBD are relevant due to lack of evidence in this condition. The iden...

journal_title：European journal of neurology

authors： Carli G,Caminiti SP,Galbiati A,Marelli S,Casoni F,Padovani A,Ferini-Strambi L,Perani D

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS)-related genes and mutations have been increasingly discovered recently and an improved understanding of genotype-phenotype relationships may help to predict the disease course and refine genetic diagnosis. METHODS:We collected clinical data and blood samples f...

journal_title：European journal of neurology

authors： Chen W,Xie Y,Zheng M,Lin J,Huang P,Pei Z,Yao X

更新日期：2020-06-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic and potentially highly disabling disorder with considerable social impact and economic consequences. It is the major cause of non-traumatic disability in young adults. The social costs associated with MS are high because of its long duration, the early loss of productivity, the nee...

journal_title：European journal of neurology

authors： Pugliatti M,Rosati G,Carton H,Riise T,Drulovic J,Vécsei L,Milanov I

更新日期：2006-07-01 00:00:00

abstract：:The present review of epidemiologic studies on migraine and headache in Europe is part of a larger initiative by the European Brain Council to estimate the costs incurred because of brain disorders. Summarizing the data on 1-year prevalence, the proportion of adults in Europe reporting headache was 51%, migraine 14%, ...

journal_title：European journal of neurology

authors： Stovner LJ,Zwart JA,Hagen K,Terwindt GM,Pascual J

更新日期：2006-04-01 00:00:00

abstract：:We describe a case of transient global amnesia related to symptomatic renal stones. Transient global amnesia has been related to intense emotional or painful experiences, such as sexual intercourse, cold water bathing and trigeminal stimulation. Renal stones may be at the origin of a painful experience and thus may in...

journal_title：European journal of neurology

authors： Kettaneh A,Gobron C,Fain O,Mohib S,Thomas M

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Progressive multifocal leukoencephalopathy (PML) is a severe infection caused by the polyomavirus JC that develops in the central nervous system (CNS) of immunosuppressed patients. The infection frequently starts in the brain hemispheres and can spread into other CNS regions such as the brainstem...

journal_title：European journal of neurology

authors： Breville G,Koralnik IJ,Lalive PH

更新日期：2020-10-30 00:00:00

abstract：BACKGROUND AND PURPOSE:It is well established that patient-related constitutional features predispose to focal peripheral neuropathies. Some of these risk factors were investigated in common focal neuropathies encountered in patients referred for electromyography. METHODS:Gender, age, height and body mass index (BMI) ...

journal_title：European journal of neurology

authors： Martínez-Aparicio C,Jääskeläinen SK,Puksa L,Reche-Lorite F,Torné-Poyatos P,Paniagua Soto J,Falck B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although there is growing and convincing evidence that socially deprived patients are at higher risk of stroke and worse outcomes, it remains controversial whether or not they suffer more severe stroke. This study aimed to evaluate the influence of social deprivation on initial clinical severity ...

journal_title：European journal of neurology

authors： Béjot Y,Guilloteau A,Joux J,Lannuzel A,Mimeau E,Mislin-Tritsch C,Fournel I,Bonithon-Kopp C,INDIA Study Group.

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our study aims to evaluate retinal function and neural conduction in post-retinal visual pathways of patients with non-arteritic ischaemic optic neuropathy (NION). METHODS:Twenty patients (mean age: 63.7 +/- 5.96 year) with NION and 20 age-similar control subjects were enrolled. Simultaneous rec...

journal_title：European journal of neurology

authors： Parisi V,Gallinaro G,Ziccardi L,Coppola G

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Headache has been associated with various lifestyle and psychosocial factors, one of which is smoking. The aim of the present study was to investigate whether the association between smoking intensity and headache is likely to be causal. METHOD:A total of 58 316 participants from the Nord-Trønde...

journal_title：European journal of neurology

authors： Johnsen MB,Winsvold BS,Børte S,Vie GÅ,Pedersen LM,Storheim K,Skorpen F,Hagen K,Bjørngaard JH,Åsvold BO,Zwart JA

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Many patients with multiple sclerosis (MS) present swallowing difficulties. Dysphagia is associated with significant morbidity and mortality, has a profound impact on the quality of life but is under-reported by patients. The objective was to investigate the psychometric properties of the Dysphag...

journal_title：European journal of neurology

authors： Printza A,Boziki M,Bakirtzis C,Nikolaidis I,Kalaitzi M,Triaridis S,Grigoriadis N

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The objective of this study was to clarify the influence of regional cerebral blood flow (rCBF) changes in language-relevant areas of the dominant hemisphere on rCBF in each region in the non-dominant hemisphere in post-stroke aphasic patients. METHODS:The study subjects were 27 aphasic patients who suffere...

journal_title：European journal of neurology

authors： Uruma G,Kakuda W,Abo M

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Observational study to evaluate long-term effects of deep brain stimulation (DBS) of the globus pallidus internus (GPi) and the ventral intermediate thalamic nucleus (VIM) on patients with medically refractory myoclonus dystonia (MD). BACKGROUND:More recently, pallidal as well as thalamic DBS have been appli...

journal_title：European journal of neurology

authors： Krause P,Koch K,Gruber D,Kupsch A,Gharabaghi A,Schneider GH,Kühn AA

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND AND PURPOSE:Anosognosia refers to a deficit of self-awareness or impaired insight for cognitive and behavioral problems. Cognitive anosognosia was explored in de novo patients with Parkinson's disease (PD) and its relationship to cognitive function and neuropsychiatric symptoms was investigated. METHODS:The...

journal_title：European journal of neurology

authors： Yoo HS,Chung SJ,Lee YH,Ye BS,Sohn YH,Lee PH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The purpose of the study is to investigate the epidemiology and medical expenses of Wilson's disease in Taiwan. METHODS:Cases of Wilson's disease were identified from the National Health Insurance Research Database with corresponding International Classification of Diseases, Ninth Revision (ICD-9) code 275....

journal_title：European journal of neurology

authors： Lai CH,Tseng HF

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Progressive multifocal leucoencephalopathy-associated immune reconstitution inflammatory syndrome (PML-IRIS) is the paradoxical worsening or unmasking of preexisting infection with JC virus attributable to a rapid recovery of the immune system after highly active antiretroviral therapy (HAART) in...

journal_title：European journal of neurology

authors： Sainz-de-la-Maza S,Casado JL,Pérez-Elías MJ,Moreno A,Quereda C,Moreno S,Corral I

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The HLA-DRB1*15 allele is consistently associated with multiple sclerosis (MS) susceptibility in most studied populations. This study investigated the association between HLA-DRB1 alleles and the presence of oligoclonal immunoglobulin G bands (OCB) in the cerebrospinal fluid (CSF) in a Spanish ...

journal_title：European journal of neurology

authors： Romero-Pinel L,Martínez-Yélamos S,Bau L,Matas E,Gubieras L,María Pujal J,Morandeira F,Bas J,Arbizu T

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subthreshold depression (SubD) is characterized by clinically relevant depressive symptoms not meeting criteria for major depression. The possible association of SubD with subjective cognitive complaints and/or objective cognitive impairments was investigated in a sample of consecutive, non-demen...

journal_title：European journal of neurology

authors： Santangelo G,Vitale C,Trojano L,Angrisano MG,Picillo M,Errico D,Agosti V,Grossi D,Barone P

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Depigmentation of the substantia nigra (SN) and locus coeruleus (LC) is a conspicuous pathological feature of Parkinson's disease (PD) and is related to the loss of neuromelanin, whose paramagnetic properties result in high signal on specific T1-weighted magnetic resonance imaging (MRI). Recent studies have ...

journal_title：European journal of neurology

authors： Reimão S,Pita Lobo P,Neutel D,Correia Guedes L,Coelho M,Rosa MM,Ferreira J,Abreu D,Gonçalves N,Morgado C,Nunes RG,Campos J,Ferreira JJ

更新日期：2015-03-01 00:00:00

abstract：:Allodynia--perception of pain from non-noxious stimuli--is a common clinical feature in various pain syndromes. The significance for migraine has increasingly been recognized and the pathophysiology has been investigated in detail. Allodynia is a marker for sensitization of central trigeminal neurons. Intensity and pe...

journal_title：European journal of neurology

authors： Schürks M,Diener HC

更新日期：2008-12-01 00:00:00