A randomly assigned double-blind cross-over study examining the relative anti-parkinsonian tremor effects of pramipexole and pergolide.

abstract：:This paper describes 10 core features of a neuropsychological assessment with the aim of helping neurologists understand the unique contribution the evaluation can make within the wider context of diagnostic methods in epilepsy. The possibilities, limitations and cautions associated with the investigation are discusse...

journal_title：European journal of neurology

authors： Baxendale SA,Wilson SJ,Baker GA,Barr W,Helmstaedter C,Hermann BP,Langfitt J,Reuner G,Rzezak P,Samson S,Smith ML

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:A Task Force was convened by the EFNS/MDS-ES Scientist Panel on Parkinson's disease (PD) and other movement disorders to systemically review relevant publications on the diagnosis of PD. METHODS:Following the EFNS instruction for the preparation of neurological diagnostic guidelines, recommendation levels h...

journal_title：European journal of neurology

authors： Berardelli A,Wenning GK,Antonini A,Berg D,Bloem BR,Bonifati V,Brooks D,Burn DJ,Colosimo C,Fanciulli A,Ferreira J,Gasser T,Grandas F,Kanovsky P,Kostic V,Kulisevsky J,Oertel W,Poewe W,Reese JP,Relja M,Ruzicka E,Sc

更新日期：2013-01-01 00:00:00

abstract：:In this report, we present the clinical and pathological details of a kindred of four individuals with a novel missense mutation (V272A) of the presenilin 1 gene (PSEN1) that experienced a subcortical dementia. The age of onset of symptoms ranged 26-36-year old, with an age at death of 36-46 years. Initial symptom was...

journal_title：European journal of neurology

authors： Jimenez-Escrig A,Rabano A,Guerrero C,Simon J,Barquero MS,Güell I,Ginestal RC,Montero T,Orensanz L

更新日期：2004-10-01 00:00:00

abstract：:We here present the case of a patient with a sleep disturbance attributed to the exploding head syndrome, recently redefined as 'episodic cranial sensory shock'. The patient, who suffered with concomitant migraine, was treated for headache prevention with daily single-pulse transcranial magnetic stimulation. Following...

journal_title：European journal of neurology

authors： Puledda F,Moreno-Ajona D,Goadsby PJ

更新日期：2021-01-18 00:00:00

abstract：:Malignancy-related thromboembolism, so-called Trousseau's syndrome, can present as acute cerebral infarction, non-bacterial thrombotic endocarditis (NBTE) and migratory thrombophlebitis. It is usually attributed to a cancer-related hypercoagulable state, chronic disseminated intravascular coagulopathy (DIC), or tumour...

journal_title：European journal of neurology

authors： Tasi SH,Juan CJ,Dai MS,Kao WY

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Variations in the treatment of multiple sclerosis (MS) occur. This study was performed to obtain insight into the reasons why patients with MS use or do not use immunomodulating treatment (DMT). METHODS:We held a survey on the use of DMT in a group of 1572 patients with MS. RESULTS:Response rate was 89%. O...

journal_title：European journal of neurology

authors： Visser LH,van der Zande A

更新日期：2011-11-01 00:00:00

abstract：:We report a novel missense mutation of the Notch3 gene in a Japanese family with CADASIL. The Cys49Gly mutation in this family is located in exon 2 of the Notch3 gene. Most of the documented Notch3 gene mutations occur in exons 3 or 4. On the other hand, there are few reports around the world of mutations in exon 2 of...

journal_title：European journal of neurology

authors： Oki K,Nagata E,Ishiko A,Shimizu A,Tanaka K,Takahashi K,Tabira T,Katayama T,Suzuki N

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Several metabolic derangements associated with diabetes mellitus type 2 (DM) have been associated with a better outcome in amyotrophic lateral sclerosis (ALS), including hyperlipidemia and obesity. Here, we tested the hypothesis that DM would have a positive effect on the motor and cognitive findings of ALS....

journal_title：European journal of neurology

authors： Jawaid A,Salamone AR,Strutt AM,Murthy SB,Wheaton M,McDowell EJ,Simpson E,Appel SH,York MK,Schulz PE

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Information about metabolic comorbidities in patients with multiple sclerosis (MS) is scarce. Our aim was to examine the prevalence of the metabolic syndrome (MetS) and its components in patients with long duration of MS and significant disability. METHODS:Demographic and clinical data, weight, ...

journal_title：European journal of neurology

authors： Pinhas-Hamiel O,Livne M,Harari G,Achiron A

更新日期：2015-09-01 00:00:00

abstract：:The incidence of the neuropathological lesions and the severity of the clinical symptoms in multiple sclerosis (MS) are correlated with the amount of the transferred autoreactive T cells. The balance between the T helper 1 (Th1) and T helper 2 (Th2) cytokine phenotypes may affect the activity of the disease in MS pati...

journal_title：European journal of neurology

authors： Ersoy E,Kuş CN,Sener U,Coker I,Zorlu Y

更新日期：2005-03-01 00:00:00

abstract：:A case is described in which non-convulsive status epilepticus (NCSE) prompted further investigation leading to the diagnosis of Lafora body disease (LBD). The onset of NCSE was temporally related to the withdrawal of sodium valproate and introduction of carbamazepine, which may have been precipitating factors. NCSE h...

journal_title：European journal of neurology

authors： Corkill RG,Hardie RJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Charcot-Marie-Tooth (CMT) disease is a chronic, slowly progressing disorder. The lack of specific disease progression biomarkers limits the execution of clinical trials. However, neurofilament light chain (NfL) has been suggested as a potential biomarker for peripheral nervous system disorders. ...

journal_title：European journal of neurology

authors： Millere E,Rots D,Simrén J,Ashton NJ,Kupats E,Micule I,Priedite V,Kurjane N,Blennow K,Gailite L,Zetterberg H,Kenina V

更新日期：2020-12-19 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose was to evaluate the association between the left ventricular ejection fraction (LVEF) and cerebral small vessel disease (cSVD) in ischaemic stroke patients. METHODS:Consecutive first-ever ischaemic stroke patients between 2010 and 2013 were included. White matter hyperintensity (WMH)...

journal_title：European journal of neurology

authors： Nam KW,Kwon HM,Kim HL,Lee YS

更新日期：2019-05-01 00:00:00

abstract：:The present study aimed to assess the ability in objects and actions naming in Parkinson's disease (PD) patients. Further, we wished to assess the effect of a particular conceptual dimension, i.e. manipulability, on the naming of object and actions. Patients were recruited from the Department of Neurology, University ...

journal_title：European journal of neurology

authors： Cotelli M,Borroni B,Manenti R,Zanetti M,Arévalo A,Cappa SF,Padovani A

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The guidelines for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) therapy suggest to use immunoglobulins (IVIg) and steroid as first-line therapies. Patients who do not respond to one of the two drugs should be switched to the other drug. We collected therapeutic outcome data in...

journal_title：European journal of neurology

authors： Cocito D,Paolasso I,Antonini G,Benedetti L,Briani C,Comi C,Fazio R,Jann S,Matà S,Mazzeo A,Sabatelli M,Nobile-Orazio E,Italian Network for CIDP Register.

更新日期：2010-02-01 00:00:00

abstract：:In a previous, controlled study we demonstrated that the general lower limb activity measured by three-channel actometry is a promising objective measure of restless legs syndrome (RLS) severity. In the present study we have further evaluated the method in measuring RLS symptom severity in an open, single-day pramipex...

journal_title：European journal of neurology

authors： Tuisku K,Holi MM,Wahlbeck K,Ahlgren AJ,Lauerma H

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:These EFNS guidelines on the molecular diagnosis of neurogenetic disorders are designed to provide practical help for the general neurologist to make appropriate use of molecular genetics in diagnosing neurogenetic disorders. Since the publication of the first two EFNS-guideline papers on the mol...

journal_title：European journal of neurology

authors： Harbo HF,Finsterer J,Baets J,Van Broeckhoven C,Di Donato S,Fontaine B,De Jonghe P,Lossos A,Lynch T,Mariotti C,Schöls L,Spinazzola A,Szolnoki Z,Tabrizi SJ,Tallaksen C,Zeviani M,Burgunder JM,Gasser T,EFNS.

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In 2005, we presented for the first time overall estimates of annual costs for brain disorders (mental and neurologic disorders) in Europe. This new report presents updated, more accurate, and comprehensive 2010 estimates for 30 European countries. METHODS:One-year prevalence and annual cost per...

journal_title：European journal of neurology

authors： Olesen J,Gustavsson A,Svensson M,Wittchen HU,Jönsson B,CDBE2010 study group.,European Brain Council.

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Migraine with aura (MA) has been found to be a risk factor for cardiovascular disease including ischaemic stroke and myocardial infarction. Studies have also reported a higher prevalence of unfavourable cardiovascular risk factors amongst migraineurs, but results have been conflicting as to whether this is r...

journal_title：European journal of neurology

authors： Winsvold BS,Hagen K,Aamodt AH,Stovner LJ,Holmen J,Zwart JA

更新日期：2011-03-01 00:00:00

abstract：:Glyceryl trinitrate, a prodrug of nitric oxide, induces a mild to moderate headache in healthy subjects, whilst migraineurs develop a more severe headache, resembling spontaneous migraine attacks. In order to investigate whether this increased nitric oxide sensitivity depends upon the frequency of spontaneously occurr...

journal_title：European journal of neurology

authors： Christiansen I,Daugaard D,Lykke Thomsen L,Olesen J

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To examine the frequencies and clinical characteristics of fallers and non-fallers at different stages of Parkinson's disease (PD). METHODS:The sample consisted of 232 patients in an unselected cross-sectional cohort of patients with PD, 207 newly diagnosed and drug naive patients and 175 contro...

journal_title：European journal of neurology

authors： Hiorth YH,Lode K,Larsen JP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thirty per cent of amyotrophic lateral sclerosis (ALS) patients have non-motor symptoms, including executive and memory deficits. The in vivo anatomical basis of memory deficits in ALS has not been elucidated. In this observational study, brain atrophy in relation to memory function was investiga...

journal_title：European journal of neurology

authors： Raaphorst J,van Tol MJ,de Visser M,van der Kooi AJ,Majoie CB,van den Berg LH,Schmand B,Veltman DJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Very-long-chain acyl-CoA dehydrogenase deficiency (VLCADD) is a hereditary disorder of mitochondrial long-chain fatty acid oxidation that has variable presentations, including exercise intolerance, cardiomyopathy and liver disease. The aim of this study was to describe the clinical and genetic ma...

journal_title：European journal of neurology

authors： Fatehi F,Okhovat AA,Nilipour Y,Mroczek M,Straub V,Töpf A,Palibrk A,Peric S,Rakocevic Stojanovic V,Najmabadi H,Nafissi S

更新日期：2020-11-01 00:00:00

abstract：:Charcot-Marie-Tooth disease (CMT) has been classified into two types: demyelinating forms (CMT1) and axonal forms (CMT2). Mutations in the CMT2A locus have been linked to the KIF1B and the mitofusin 2 (MFN2) genes. Here, we report a German patient with CMT2 with an underlying spontaneous mutation (c.281G-->A) in the M...

journal_title：European journal of neurology

authors： Neusch C,Senderek J,Eggermann T,Elolff E,Bähr M,Schneider-Gold C

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The frequency of sural sensory nerve action potential (SNAP) abnormalities in large fibre sensory neuropathy (LFSN) is uncertain. When sural SNAPs are normal, the sural/radial amplitude ratio (SRAR) was found to improve diagnostic yield in some studies. Motor parameters have been studied rarely, but may be h...

journal_title：European journal of neurology

authors： Rajabally YA,Beri S,Bankart J

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The coronavirus disease 2019 (COVID-19) pandemic challenges neurologists in counseling multiple sclerosis (MS) patients with respect to their risk for and by severe acute respiratory syndrome coronavirus 2 and in guiding disease-modifying treatment (DMT). The objective was to determine the freque...

journal_title：European journal of neurology

authors： Bsteh G,Bitschnau C,Hegen H,Auer M,Di Pauli F,Rommer P,Deisenhammer F,Berger T

更新日期：2020-09-25 00:00:00

abstract：:In visual evoked potential studies, habituation during stimulus repetition with the same stimulus at a constant intensity has been found to be abnormal in migraineurs between attacks. The purpose of this study was to investigate habituation of somatosensory evoked potentials (SEPs) and the effects of migraine on them....

journal_title：European journal of neurology

authors： Ozkul Y,Uckardes A

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this prospective study was to show and compare the rate of large-fiber involvement with near-nerve needle sensory (NNNS) nerve conduction study (NCS) and with medial plantar NCS recorded with surface electrodes in a group of patients who had clinically pure small-fiber sensory neuropat...

journal_title：European journal of neurology

authors： Uluc K,Temucin CM,Ozdamar SE,Demirci M,Tan E

更新日期：2008-09-01 00:00:00

abstract：:To determine the clinical features, prognostic factors, and therapeutic results of Guillain-Barré syndrome (GBS) in order to improve the therapeutic strategy for this disease. We retrospectively reviewed the electrodiagnostic study and medical records of patients with GBS admitted to Chang Gung Memorial Hospital, Kaoh...

journal_title：European journal of neurology

authors： Cheng BC,Chang WN,Chang CS,Chee CY,Huang CR,Chen JB,Chang CJ,Hung PL,Wang KW,Chang HW,Lu CH

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Friedreich's ataxia (FRDA) is the most common autosomal-recessive ataxia worldwide. It is characterized by early onset, sensory abnormalities and slowly progressive ataxia. All magnetic resonance imaging (MRI)-based studies have focused on the evaluation of adult patients. Therefore, we designed ...

journal_title：European journal of neurology

authors： Rezende TJR,Martinez ARM,Faber I,Girotto Takazaki KA,Martins MP,de Lima FD,Lopes-Cendes I,Cendes F,França MC Jr

更新日期：2019-03-01 00:00:00