Association between remote diffusion-weighted imaging lesions and cerebral small vessel disease in primary intracerebral hemorrhage.

Abstract:

BACKGROUND AND PURPOSE:The aim of this study was to examine the association amongst remote diffusion-weighted imaging lesions (R-DWILs), imaging markers of cerebral small vessel disease (cSVD) and total cSVD burden in patients with primary intracerebral haemorrhage (ICH). METHODS:In total, 344 consecutive primary ICH patients were enrolled prospectively. R-DWILs on magnetic resonance imaging as well as four imaging markers of cSVD, including cerebral microbleeds (CMBs), white matter hyperintensities (WMHs), lacunes and enlarged perivascular spaces, were rated with validated scales. The total cSVD score was calculated by adding up these four markers. Univariate and multivariate analyses were performed. RESULTS:Remote DWI lesions were detected in 57 (16.6%) primary ICH patients. On multivariate logistic regression analysis, the presence of CMBs [odds ratio (OR) 5.26, 95% confidence interval (CI) 1.72-16.12], of high-grade WMHs (OR 4.68, 95% CI 2.01-10.90), the presence of lacunes (OR 2.69, 95% CI 1.20-6.06), mixed CMBs (OR 2.93, 95% CI 1.35-6.36), mixed lacunes (OR 3.60, 95% CI 1.25-10.37), periventricular WMHs (OR 2.19, 95% CI 1.40-3.44), deep WMHs (OR 1.92, 95% CI 1.24-2.97) and total WMHs (OR 1.52, 95% CI 1.20-1.94) were associated with the presence of R-DWILs. A significant association was also found between high-grade total cSVD score and R-DWILs (OR 1.97, 95% CI 1.36-2.84). This association remained significant in patients stratified by an age of 60 years or more than 60 years. CONCLUSIONS:Remote DWI lesions are correlated with the severity of each imaging marker of cSVD and with the total burden of cSVD.

journal_name

Eur J Neurol

authors

Xu XH,Ye XH,Li JW,Cai JS,Gao T,Zhang WJ,Zhao GH,Tong LS,Gao F

doi

10.1111/ene.13915

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

961-968

issue

7

eissn

1351-5101

issn

1468-1331

journal_volume

26

pub_type

杂志文章
  • Activities in the Danish Year of the Brain 1997.

    abstract::In this paper we report about the Danish Year of the Brain 1997 because it may serve as a model for other countries. It was possible in Denmark to organize a very large scale effort which has been well received by the general public and which has significantly improved the image of the neurological disciplines. The re...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1046/j.1468-1331.1998.560619.x

    authors: Olesen J,Oberg G,Vestergaard P

    更新日期:1998-11-01 00:00:00

  • Spasms in children with definite and probable mitochondrial disease.

    abstract::The diagnosis of mitochondrial encephalomyopathies is complex and a system for classification of the diagnosis as definite, probable, and possible has been proposed. The objective of this study was to explore the spectrum of epileptic disorders associated with probable and definite mitochondrial disease in children us...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1046/j.1351-5101.2003.00724.x

    authors: Sadleir LG,Connolly MB,Applegarth D,Hendson G,Clarke L,Rakshi C,Farrell K

    更新日期:2004-02-01 00:00:00

  • Substantia nigra neuromelanin magnetic resonance imaging in de novo Parkinson's disease patients.

    abstract:BACKGROUND:Depigmentation of the substantia nigra (SN) and locus coeruleus (LC) is a conspicuous pathological feature of Parkinson's disease (PD) and is related to the loss of neuromelanin, whose paramagnetic properties result in high signal on specific T1-weighted magnetic resonance imaging (MRI). Recent studies have ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.12613

    authors: Reimão S,Pita Lobo P,Neutel D,Correia Guedes L,Coelho M,Rosa MM,Ferreira J,Abreu D,Gonçalves N,Morgado C,Nunes RG,Campos J,Ferreira JJ

    更新日期:2015-03-01 00:00:00

  • Striatal dopamine transporter binding in patients with Parkinson's disease and severe occupational hydrocarbon exposure.

    abstract::We used 123I-Ioflupane SPECT to study striatal dopamine transporter (DAT) binding in 36 Parkinson's disease (PD) patients with history of severe occupational exposure to hydrocarbons. Data were compared with 38 PD patients without exposure history as well as healthy controls. Both PD cohorts showed significant striata...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2006.01642.x

    authors: Canesi M,Benti R,Marotta G,Cilia R,Isaias IU,Gerundini P,Pezzoli G,Antonini A

    更新日期:2007-03-01 00:00:00

  • Electrophysiological markers of large fibre sensory neuropathy: a study of sensory and motor conduction parameters.

    abstract:BACKGROUND:The frequency of sural sensory nerve action potential (SNAP) abnormalities in large fibre sensory neuropathy (LFSN) is uncertain. When sural SNAPs are normal, the sural/radial amplitude ratio (SRAR) was found to improve diagnostic yield in some studies. Motor parameters have been studied rarely, but may be h...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2009.02651.x

    authors: Rajabally YA,Beri S,Bankart J

    更新日期:2009-09-01 00:00:00

  • Multiple sclerosis in Oslo, Norway: prevalence on 1 January 1995 and incidence over a 25-year period.

    abstract::The Oslo Multiple Sclerosis (MS) Registry was established in 1990, and this is the first report on the prevalence and incidence of MS in the city of Oslo, Norway. The prevalence rate of definite MS on 1 January 1995 was 120.4/10(5). Inclusion of patients of native Norwegian ancestry only and exclusion of non-Norwegian...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1046/j.1468-1331.2001.00269.x

    authors: Celius EG,Vandvik B

    更新日期:2001-09-01 00:00:00

  • Perimysial microarteriopathy in dermatomyositis with anti-nuclear matrix protein-2 antibodies.

    abstract:BACKGROUND AND PURPOSE:Dermatomyositis (DM) with anti-nuclear matrix protein-2 (NXP-2) antibodies usually shows multifocal ischaemic lesions in muscle. Here, we aimed to investigate the microarteriopathy underlying muscle ischaemia in anti-NXP-2-positive DM. METHODS:A total of 16 patients diagnosed with anti-NXP-2-pos...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14097

    authors: Liu Y,Zheng Y,Gang Q,Xie Z,Jin Y,Zhang X,Deng X,Hao H,Gao F,Zhang Z,Xiong H,Zhang W,Wang Z,Yuan Y

    更新日期:2020-03-01 00:00:00

  • Acute ischaemic lesions are associated with cortical superficial siderosis in spontaneous intracerebral hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Diffusion-weighted imaging (DWI) commonly detects acute ischaemic lesions in patients with acute intracerebral hemorrhage (ICH), especially with cerebral amyloid angiopathy (CAA). We investigated the relationship between cortical superficial siderosis (cSS), a neuroimaging marker of CAA, and DWI ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13874

    authors: Revel-Mouroz P,Viguier A,Cazzola V,Calviere L,Patsoura S,Rousseau V,Sommet A,Albucher JF,Cognard C,Olivot JM,Bonneville F,Raposo N

    更新日期:2019-04-01 00:00:00

  • Functional connectivity and topology in patients with restless legs syndrome: a case-control resting-state functional magnetic resonance imaging study.

    abstract:BACKGROUND AND PURPOSE:Functional connectivity studies revealed alterations within thalamic, salience, and default mode networks in restless legs syndrome patients. METHODS:Eighty-two patients with restless legs syndrome (untreated, n = 30; on dopaminergic medication, n = 42; on alpha-2-delta ligands as mono- or polyt...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14577

    authors: Tuovinen N,Stefani A,Mitterling T,Heidbreder A,Frauscher B,Gizewski ER,Poewe W,Högl B,Scherfler C

    更新日期:2021-02-01 00:00:00

  • Factors related to respiration influencing survival and respiratory function in patients with amyotrophic lateral sclerosis: a retrospective study.

    abstract:BACKGROUND:Various breathing abnormalities (Neurology 2009; 73: 1218) have been proposed as indicators for the introduction of non-invasive positive-pressure ventilation (NIV) in patients with amyotrophic lateral sclerosis (ALS). We were interested in the usefulness of symptoms of respiratory insufficiency and abnormal...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2012.03754.x

    authors: Leonardis L,Dolenc Grošelj L,Vidmar G

    更新日期:2012-12-01 00:00:00

  • Cost-effectiveness of decompressive craniectomy in non-traumatic neurological emergencies.

    abstract:BACKGROUND:Decompressive craniectomy is used regularly in traumatic brain injury (TBI) and malignant middle cerebral artery infarction. Its benefits for other causes of non-traumatic brain swelling, if any, are unclear, especially after a devastating primary event. METHODS:We evaluated the outcomes as well as treatmen...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2010.03162.x

    authors: Malmivaara K,Ohman J,Kivisaari R,Hernesniemi J,Siironen J

    更新日期:2011-03-01 00:00:00

  • Clinical significance of subcortical vascular disease in patients with mild cognitive impairment.

    abstract::Patients with mild cognitive impairment (MCI) typically present with memory complaints. Some of these patients have subcortical vascular disease on computed tomography (CT) scan, namely white matter changes and lacunar infarcts, however it is not known whether these findings are associated with more pronounced cogniti...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2004.00892.x

    authors: de Mendonça A,Ribeiro F,Guerreiro M,Palma T,Garcia C

    更新日期:2005-02-01 00:00:00

  • Can we use peripheral tissue biopsies to diagnose Parkinson's disease? A review of the literature.

    abstract::Phosphorylated α-synuclein (phosαSYN) containing inclusions in neurons (Lewy bodies, LB) and nerve terminals (Lewy neurites, LN), the pathological hallmark of Parkinson's disease (PD), are not confined to the central nervous system, but have also been reported in peripheral tissues. However, the usefulness of αSYN/pho...

    journal_title:European journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1111/ene.12753

    authors: Schneider SA,Boettner M,Alexoudi A,Zorenkov D,Deuschl G,Wedel T

    更新日期:2016-02-01 00:00:00

  • Pyridostigmine bromide versus fludrocortisone in the treatment of orthostatic hypotension in Parkinson's disease - a randomized controlled trial.

    abstract:BACKGROUND AND PURPOSE:Evidence for effective treatment options for orthostatic hypotension (OH) in Parkinson's disease (PD) is scarce. Elevation of cholinergic tone with pyridostigmine bromide has been reported as a way to improve blood pressure (bp) regulation in neurogenic hypotension without causing supine hyperten...

    journal_title:European journal of neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ene.13260

    authors: Schreglmann SR,Büchele F,Sommerauer M,Epprecht L,Kägi G,Hägele-Link S,Götze O,Zimmerli L,Waldvogel D,Baumann CR

    更新日期:2017-04-01 00:00:00

  • Variables linked to psychotic symptoms in Alzheimer's disease.

    abstract::This study is aimed at assessing the prevalence and features of psychotic symptoms in a sample of 180 patients with Alzheimer's disease (AD). Sixty-four patients (35.5% of the sample) showed one or more psychotic symptoms. The presence of these symptoms correlated with the severity of the patients' cognitive impairmen...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1046/j.1468-1331.1998.560553.x

    authors: Sala SD,Francescani A,Muggia S,Spinnler H

    更新日期:1998-11-01 00:00:00

  • Overactive bladder in Parkinson's disease: alteration of brainstem raphe detected by transcranial sonography.

    abstract::Urinary dysfunction is very common in idiopathic Parkinson's disease (PD) and manifests primarily with symptoms of overactive bladder (OAB). Affection of central serotonergic systems has been suggested to play a role in OAB. The objective of this study was to evaluate whether in PD patients with OAB symptoms a specifi...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2006.01463.x

    authors: Walter U,Dressler D,Wolters A,Wittstock M,Benecke R

    更新日期:2006-12-01 00:00:00

  • Practice recommendations for neurovascular ultrasound investigations of acute stroke patients in the setting of the COVID-19 pandemic: an expert consensus from the European Society of Neurosonology and Cerebral Hemodynamics.

    abstract:BACKGROUND AND PURPOSE:Patients with acute ischemic stroke are at high-risk for contracting COVID-19 infection. Additionally, healthcare professionals including neurovascular ultrasound providers are also at risk of being infected by SARS-CoV-2 virus. Yet, preparedness to continue to guarantee hyperacute treatment is v...

    journal_title:European journal of neurology

    pub_type: 杂志文章,实务指引

    doi:10.1111/ene.14334

    authors: Baracchini C,Pieroni A,Kneihsl M,Azevedo E,Diomedi M,Pascazio L,Wojczal J,Lucas C,Bartels E,Bornstein NM,Csiba L,Valdueza J,Tsivgoulis G,Malojcic B

    更新日期:2020-09-01 00:00:00

  • Serum uric acid levels correlate with benign paroxysmal positional vertigo.

    abstract:BACKGROUND AND PURPOSE:Benign paroxysmal positional vertigo (BPPV) is a frequently encountered condition that can severely affect the quality of life. In this study, we aimed to assess the possible relations between serum uric acid (SUA) levels and BPPV. METHODS:Fifty patients with BPPV, and 40 age- and sex-matched co...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.12248

    authors: Celikbilek A,Gencer ZK,Saydam L,Zararsiz G,Tanik N,Ozkiris M

    更新日期:2014-01-01 00:00:00

  • A multicenter study of transient global amnesia for the better detection of magnetic resonance imaging abnormalities.

    abstract:BACKGROUND AND PURPOSE:The detection rate of diffusion-weighted (DWI) hyperintense lesions varies widely in patients with transient global amnesia (TGA). The aim was to examine the association of hyperintense lesions on DWI magnetic resonance imaging (MRI) with patient characteristics, precipitating factors, clinical p...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14408

    authors: Higashida K,Okazaki S,Todo K,Sasaki T,Ohara N,Kohara N,Yamamoto S,Yamagami H,Hashikawa K,Yoshimoto T,Ihara M,Koga M,Szabo K,Mochizuki H

    更新日期:2020-11-01 00:00:00

  • Trousseau's syndrome related to adenocarcinoma of the colon and cholangiocarcinoma.

    abstract::Malignancy-related thromboembolism, so-called Trousseau's syndrome, can present as acute cerebral infarction, non-bacterial thrombotic endocarditis (NBTE) and migratory thrombophlebitis. It is usually attributed to a cancer-related hypercoagulable state, chronic disseminated intravascular coagulopathy (DIC), or tumour...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2004.00814.x

    authors: Tasi SH,Juan CJ,Dai MS,Kao WY

    更新日期:2004-07-01 00:00:00

  • Intracortical inhibition and facilitation are impaired in patients with early Parkinson's disease: a paired TMS study.

    abstract::Twelve patients with early Parkinson's disease (PD), none of whom had received any previous L-DOPA treatment, but using other antiparkinsonian drugs, were studied using transcranial magnetic stimulation (TMS). Contralateral and ipsilateral hemispheres were examined, with a focus on the more pronounced parkinsonian sym...

    journal_title:European journal of neurology

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1468-1331.2003.00610.x

    authors: Bares M,Kanovský P,Klajblová H,Rektor I

    更新日期:2003-07-01 00:00:00

  • Serum soluble ST2 is a potential long-term prognostic biomarker for transient ischaemic attack and ischaemic stroke.

    abstract:BACKGROUND AND PURPOSE:Soluble ST2 (sST2) is a promising biomarker in inflammation, atherosclerosis and cardiovascular diseases. We investigated the association between serum sST2 and poor outcome in patients with transient ischaemic attack (TIA)/ischaemic stroke. METHODS:Patients within 24 h after onset and with meas...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14419

    authors: Tian X,Guo Y,Wang X,Pei L,Wang X,Wu J,Sun S,Li Y,Ning M,Buonanno FS,Xu Y,Song B

    更新日期:2020-11-01 00:00:00

  • Charcot-Marie-Tooth type X: unusual phenotype of a novel CX32 mutation.

    abstract:BACKGROUND:X-linked Charcot-Marie-Tooth disease (CMTX), caused by mutations in the gene encoding connexin32, is the second most common form of inherited demyelinating neuropathy, next to CMT 1A, and accounts for 10-20% of all hereditary demyelinating neuropathies. AIMS OF THE STUDY:To describe clinical and electrophys...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2008.02263.x

    authors: Mazzeo A,Di Leo R,Toscano A,Muglia M,Patitucci A,Messina C,Vita G

    更新日期:2008-10-01 00:00:00

  • Maurice Ravel and right-hemisphere musical creativity: influence of disease on his last musical works?

    abstract::The problem of finding correspondence between a particular neuronal organization and a specific function of the human brain remains a central question of neuroscience. It is sometimes thought that language and music are two sides of the same intellectual coin, but research on brain-damaged patients has shown that the ...

    journal_title:European journal of neurology

    pub_type: 传,历史文章,杂志文章

    doi:10.1046/j.1468-1331.2002.00351.x

    authors: Amaducci L,Grassi E,Boller F

    更新日期:2002-01-01 00:00:00

  • Cranial nerve involvement in typical and atypical chronic inflammatory demyelinating polyneuropathies.

    abstract:BACKGROUND AND PURPOSE:Cranial nerve palsy is occasionally present in patients with chronic inflammatory demyelinating polyneuropathy (CIDP), but its prevalence, characteristics and relations with the CIDP subtypes have rarely been investigated. The aim of this study was to systematically assess cranial nerve involveme...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14497

    authors: Shibuya K,Tsuneyama A,Misawa S,Suichi T,Suzuki Y,Kojima Y,Nakamura K,Kano H,Prado M,Kuwabara S

    更新日期:2020-12-01 00:00:00

  • Botulinum toxin assessment, intervention and after-care for upper limb hypertonicity in adults: international consensus statement.

    abstract::Upper limb spasticity affecting elbow, wrist, and finger flexors can be safely and effectively reduced with injections of botulinum toxin type-A (BoNT-A). It has been best studied in adults in the context of post-stroke spasticity. The clinical benefits include reduction in pain and deformity, improvement in washing a...

    journal_title:European journal of neurology

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1111/j.1468-1331.2010.03129.x

    authors: Sheean G,Lannin NA,Turner-Stokes L,Rawicki B,Snow BJ,Cerebral Palsy Institute.

    更新日期:2010-08-01 00:00:00

  • Optical coherence tomography represents a sensitive and reliable tool for routine monitoring of idiopathic intracranial hypertension with and without papilledema.

    abstract:BACKGROUND AND PURPOSE:We previously reported that certain optical coherence tomography (OCT) measures were sensitive and reliable in identifying idiopathic intracranial hypertension (IIH). This prospective study aimed to define OCT measures that allow differentiation of IIH with and without papilledema, thereby helpin...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13893

    authors: Huang-Link Y,Eleftheriou A,Yang G,Johansson JM,Apostolou A,Link H,Jin YP

    更新日期:2019-05-01 00:00:00

  • Pituitary apoplexy: a transient benign presentation mimicking mild subarachnoid hemorrhage with negative angiography.

    abstract::We report on a patient who presented with isolated transient headache as the only manifestation of pituitary apoplexy. A high index of suspicion and MRI led to the diagnosis. Copyright 1998 Lippincott Williams & Wilkins ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1046/j.1468-1331.1998.550499.x

    authors: Hernandez A,Angeles Del Real M,Aguirre M,Vaamonde J,Gudin M,Ibanez R

    更新日期:1998-09-01 00:00:00

  • Reasons patients give to use or not to use immunomodulating agents for multiple sclerosis.

    abstract:BACKGROUND:Variations in the treatment of multiple sclerosis (MS) occur. This study was performed to obtain insight into the reasons why patients with MS use or do not use immunomodulating treatment (DMT). METHODS:We held a survey on the use of DMT in a group of 1572 patients with MS. RESULTS:Response rate was 89%. O...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2011.03411.x

    authors: Visser LH,van der Zande A

    更新日期:2011-11-01 00:00:00

  • The Symbol Digit Modalities Test as sentinel test for cognitive impairment in multiple sclerosis.

    abstract:BACKGROUND AND PURPOSE:Cognitive impairment (CI) is found in about half of the multiple sclerosis (MS) population and is an important contributor to employment status and social functioning. CI is encountered in all disease stages and correlates only moderately with disease duration or Expanded Disability Status Scale ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.12463

    authors: Van Schependom J,D'hooghe MB,Cleynhens K,D'hooge M,Haelewyck MC,De Keyser J,Nagels G

    更新日期:2014-09-01 00:00:00