Intrafusal effects of botulinum toxin in post-stroke upper limb spasticity.

abstract：BACKGROUND AND PURPOSE:Risk-stratification models based on patient and disease characteristics are useful for aiding clinical decisions and for comparing the quality of care between different physicians or hospitals. In addition, prediction of mortality is beneficial for optimizing resource utilization. We evaluated th...

journal_title：European journal of neurology

authors： Peng SY,Chuang YC,Kang TW,Tseng KH

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Alternating hemiplegia of childhood (AHC) is a rare neurological disease characterized by recurrent paroxysmal attacks of hemiplegia. The aim of the study was to assess the recovery cycle of the somatosensory evoked potentials (SEPs) in a group of AHC patients. METHODS:Seven AHC patients and 10 ...

journal_title：European journal of neurology

authors： Vollono C,Rinalduzzi S,Miliucci R,Vigevano F,Valeriani M

更新日期：2014-12-01 00:00:00

abstract：:The problem of finding correspondence between a particular neuronal organization and a specific function of the human brain remains a central question of neuroscience. It is sometimes thought that language and music are two sides of the same intellectual coin, but research on brain-damaged patients has shown that the ...

journal_title：European journal of neurology

authors： Amaducci L,Grassi E,Boller F

更新日期：2002-01-01 00:00:00

abstract：:Population-based epidemiological studies on epilepsy are available mainly from the UK and the Nordic, Baltic and western Mediterranean countries. No studies were identified from large areas of Europe, especially from the former eastern Europe (except the Baltic countries) and the eastern Mediterranean countries. Based...

journal_title：European journal of neurology

authors： Forsgren L,Beghi E,Oun A,Sillanpää M

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Depressed mood is a common psychiatric problem associated with Parkinson's disease (PD), and studies have suggested a benefit of rasagiline treatment. METHODS:ACCORDO (see the ) was a 12-week, double-blind, placebo-controlled trial to evaluate the effects of rasagiline 1 mg/day on depressive sym...

journal_title：European journal of neurology

authors： Barone P,Santangelo G,Morgante L,Onofrj M,Meco G,Abbruzzese G,Bonuccelli U,Cossu G,Pezzoli G,Stanzione P,Lopiano L,Antonini A,Tinazzi M

更新日期：2015-08-01 00:00:00

abstract：:Cortical excitability of the primary motor cortex is altered in patients with Parkinson's disease (PD). Therefore, modulation of cortical excitability by high frequency repetitive transcranial magnetic stimulation (rTMS) of the motor cortex might result in beneficial effects on motor functions in PD. The present study...

journal_title：European journal of neurology

authors： Khedr EM,Farweez HM,Islam H

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion-weighted imaging (DWI) commonly detects acute ischaemic lesions in patients with acute intracerebral hemorrhage (ICH), especially with cerebral amyloid angiopathy (CAA). We investigated the relationship between cortical superficial siderosis (cSS), a neuroimaging marker of CAA, and DWI ...

journal_title：European journal of neurology

authors： Revel-Mouroz P,Viguier A,Cazzola V,Calviere L,Patsoura S,Rousseau V,Sommet A,Albucher JF,Cognard C,Olivot JM,Bonneville F,Raposo N

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is increasing interest in using patient-reported outcome measures (PROMs) in clinical studies to capture individual changes over time. However, PROMs have also been criticized because they are entirely subjective. Our objective was to examine the relationship between a subjective PROM and a...

journal_title：European journal of neurology

authors： Draak TH,Gorson KC,Vanhoutte EK,van Nes SI,van Doorn PA,Cornblath DR,van den Berg LH,Faber CG,Merkies IS,PeriNomS Study Group.

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Interferon beta (IFNbeta) preparations have some effect on the progressive phase of multiple sclerosis (MS). This limited effect might be partially because of a certain number of IFNbeta non-responders. Myxovirus resistance protein A (MxA)--a marker of IFNbeta bioactivity--was correlated with the...

journal_title：European journal of neurology

authors： Millonig A,Dressel A,Bahner D,Bitsch A,Bogumil T,Elitok E,Kitze B,Tumani H,Weber F,Gneiss C,Deisenhammer F

更新日期：2008-08-01 00:00:00

abstract：:We report here 39 cases in which definite multiple sclerosis (MS) was precipitated or exacerbated by specific hyperextension-hyperflexion cervical cord trauma. The worsening or onset of the symptomatic disease bore a striking temporal relationship to the focal injury. Our data suggests that central nervous system (CNS...

journal_title：European journal of neurology

authors： Chaudhuri A,Behan PO

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:We investigated whether the prevalence of primary headaches was higher in patients with primary Sjøgren's syndrome (PSS) than in healthy individuals. METHODS:This retrospective cohort study included 71 patients with PSS (patients) based on the American European Consensus Classification criteria, and 71 age-...

journal_title：European journal of neurology

authors： Tjensvoll AB,Harboe E,Gøransson LG,Beyer MK,Greve OJ,Kvaløy JT,Omdal R

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Porphyrias are a group of inherited metabolic disorders resulting from a specific deficiency along the pathway of haem biosynthesis. A clinical classification distinguishes acute from non-acute porphyrias considering the occurrence of life-threatening neurovisceral attacks, presenting with abdomi...

journal_title：European journal of neurology

authors： Olivier P,Van Melkebeke D,Honoré PJ,Defreyne L,Hemelsoet D

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Whether the neuromelanin-positive substantia nigra pars compacta area (NM-SNc) on neuromelanin magnetic resonance imaging (NM-MRI) and the specific binding ratio (SBR) on 123 I-N-v-fluoropropyl-2b-carbomethoxy3b-(4-iodophenyl)nortropane single photon emission computed tomography (DaT-SPECT) can b...

journal_title：European journal of neurology

authors： Okuzumi A,Hatano T,Kamagata K,Hori M,Mori A,Oji Y,Taniguchi D,Daida K,Shimo Y,Yanagisawa N,Nojiri S,Aoki S,Hattori N

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:A Task Force was convened by the EFNS/MDS-ES Scientist Panel on Parkinson's disease (PD) and other movement disorders to systemically review relevant publications on the diagnosis of PD. METHODS:Following the EFNS instruction for the preparation of neurological diagnostic guidelines, recommendation levels h...

journal_title：European journal of neurology

authors： Berardelli A,Wenning GK,Antonini A,Berg D,Bloem BR,Bonifati V,Brooks D,Burn DJ,Colosimo C,Fanciulli A,Ferreira J,Gasser T,Grandas F,Kanovsky P,Kostic V,Kulisevsky J,Oertel W,Poewe W,Reese JP,Relja M,Ruzicka E,Sc

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Body mass index (BMI), hyperglycaemia and type 2 diabetes and their interactive effects are associated with brain volume atrophy in ageing. It remains to be established if these risk factors are particularly concerning in individuals with high or low brain volumes. METHODS:Demographics, venous b...

journal_title：European journal of neurology

authors： Walsh EI,Shaw M,Sachdev P,Anstey KJ,Cherbuin N

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:  Therapy for multiple sclerosis (MS) has a partial efficacy, and a significant proportion of treated patients will develop a suboptimal response with first-line disease-modifying drugs (DMD). Therapy switch in patients with MS can be a strategy after a treatment failure. We studied the change in clinical ac...

journal_title：European journal of neurology

authors： Río J,Tintoré M,Sastre-Garriga J,Nos C,Castilló J,Tur C,Comabella M,Montalban X

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Serotoninergic dysfunction was reported to be involved in aetiology of temporal lobe epilepsy (TLE). Serotonin (5-HT) is actively cleared from synaptic cleft by serotonin transporter (5-HTT). We investigated the association between three common polymorphisms of 5-HTT gene, which may influence gen...

journal_title：European journal of neurology

authors： Li J,Lin H,Zhu X,Li L,Wang X,Sun W,Wu X,Liu A,Niu F,Wang Y,Liu Y

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Basilar artery occlusion (BAO) leads to high rates of morbidity and mortality, despite successful recanalization. The discordance between flow restoration and long-term functional status clouds clinical decision-making regarding further aggressive care. We sought to develop and validate a practic...

journal_title：European journal of neurology

authors： Jadhav AP,Desai SM,Panczykowski DM,Rangaraju S,Campbell D,Ritvonen JK,Schreiner M,Silvennoinen H,Gerber J,Puetz V,Raza SA,Haussen DC,Nogueira RG,Strbian D,Jovin TG,Lindsberg PJ

更新日期：2020-11-01 00:00:00

abstract：:Digital subtraction angiography (DSA) is considered to be the 'gold standard' for confirmation of severe (70-99%) stenoses of internal carotid arteries (ICAs). However, it is associated with a risk of complications. The aim of this study was to assess the accuracy of ultrasonography (US), computed tomographic angiogra...

journal_title：European journal of neurology

authors： Herzig R,Burval S,Krupka B,Vlachová I,Urbánek K,Mares J

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Magnetic resonance diffusivity indices have been repeatedly proposed as biomarkers of neurodegeneration in amyotrophic lateral sclerosis (ALS), but no consensus exists as to which diffusivity parameter is the most sensitive to identify early degenerative changes. Despite numerous studies, surpris...

journal_title：European journal of neurology

authors： Schuster C,Elamin M,Hardiman O,Bede P

更新日期：2016-08-01 00:00:00

abstract：:Urinary dysfunction is very common in idiopathic Parkinson's disease (PD) and manifests primarily with symptoms of overactive bladder (OAB). Affection of central serotonergic systems has been suggested to play a role in OAB. The objective of this study was to evaluate whether in PD patients with OAB symptoms a specifi...

journal_title：European journal of neurology

authors： Walter U,Dressler D,Wolters A,Wittstock M,Benecke R

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional connectivity studies revealed alterations within thalamic, salience, and default mode networks in restless legs syndrome patients. METHODS:Eighty-two patients with restless legs syndrome (untreated, n = 30; on dopaminergic medication, n = 42; on alpha-2-delta ligands as mono- or polyt...

journal_title：European journal of neurology

authors： Tuovinen N,Stefani A,Mitterling T,Heidbreder A,Frauscher B,Gizewski ER,Poewe W,Högl B,Scherfler C

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Efficacy and safety data have not previously been compiled for intramuscular interferon beta-1a (IM IFNβ-1a) in patients with multiple sclerosis (MS) ≥ 50 years of age. We investigated the efficacy and safety of IM IFNβ-1a in patients segregated by 50 and 40 years of age in separate meta-analyses. METHODS:T...

journal_title：European journal of neurology

authors： Lampl C,You X,Limmroth V

更新日期：2012-01-01 00:00:00

abstract：:A PARK8 form of Parkinson's disease (PD) is caused by a novel gene, leucine-rich repeat kinase 2 (LRRK2), and a single mutation G2019S was found in a proportion of LRRK2-associated cases of diverse ethnic origins. We performed the LRRK2 G2019S mutation analysis in 304 Russian patients with PD, including 291 sporadic a...

journal_title：European journal of neurology

authors： Illarioshkin SN,Shadrina MI,Slominsky PA,Bespalova EV,Zagorovskaya TB,Bagyeva GKh,Markova ED,Limborska SA,Ivanova-Smolenskaya IA

更新日期：2007-04-01 00:00:00

abstract：:Frontotemporal dementia (FTD) often presents with behavioural changes warranting treatment with antipsychotic medications. It is known that patients with Lewy body dementia are sensitive to developing extrapyramidal symptoms (EPS) from these medications. This has not been emphasized in FTD. We report three patients wi...

journal_title：European journal of neurology

authors： Czarnecki K,Kumar N,Josephs KA

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The National Institute for Health and Care Excellence (NICE) in the UK recommends the use of OnabotulinumtoxinA (BoNTA, Botox® ) in the management of chronic migraine (CM) following specific guidelines within the National Health Service. In view of the lack of data on the efficacy of this therapy...

journal_title：European journal of neurology

authors： Andreou AP,Trimboli M,Al-Kaisy A,Murphy M,Palmisani S,Fenech C,Smith T,Lambru G

更新日期：2018-08-01 00:00:00

abstract：:A 53-year-old man presented with optic neuritis, followed within 10 weeks by a subacute progression of weakness, ataxia, and multiple cranial nerve palsies. Cranial magnetic resonance imaging demonstrated multiple T2-hyperintense lesions extending from the ponto-medullary junction to the thalamus and internal capsule....

journal_title：European journal of neurology

authors： Zivković SA,Heyman R,Pless M

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multiple sclerosis (MS) patients discontinuing natalizumab are at risk of rebound of disease activity. METHODS:In the present multi-center, open-label, non-randomized, prospective, pilot study, we tested whether treatment with glatiramer acetate (GA) is safe and effective after natalizumab in MS...

journal_title：European journal of neurology

authors： Rossi S,Motta C,Studer V,De Chiara V,Barbieri F,Monteleone F,Fornasiero A,Coarelli G,Bernardi G,Cutter G,Stüve O,Salvetti M,Centonze D

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite advances in the understanding of Huntington's disease (HD), treatment remains symptomatic. Multidisciplinary rehabilitation, however, appears to impact disease progression. Here we show the feasibility, safety and efficacy of a 9-month multidisciplinary rehabilitation programme in a small...

journal_title：European journal of neurology

authors： Thompson JA,Cruickshank TM,Penailillo LE,Lee JW,Newton RU,Barker RA,Ziman MR

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Randomized trials and meta-analyses indicate positive effects of stroke unit (SU) care on survival and dependency of patients with stroke. However, data on the advantages of SU in 'real-world' settings are limited. We prospectively assessed, in a large University Hospital, the effect of SU versus other conve...

journal_title：European journal of neurology

authors： Di Carlo A,Lamassa M,Wellwood I,Bovis F,Baldereschi M,Nencini P,Poggesi A,Cramaro A,Pescini F,Lucente G,Wolfe CD,Inzitari D,European Registers of Stroke (EROS) Project.

更新日期：2011-05-01 00:00:00