Therapeutic effect of repetitive transcranial magnetic stimulation on motor function in Parkinson's disease patients.

abstract：BACKGROUND AND PURPOSE:The aim of our study was to describe patients with the p.D12Y variant (previously reported as D11Y) in SOD1 showing heterogeneous clinicopathological features. METHODS:We performed clinical, electrophysiological, magnetic resonance imaging (MRI) and muscle pathology studies in four SOD1 p.D12Y v...

journal_title：European journal of neurology

authors： Tasca G,Lattante S,Marangi G,Conte A,Bernardo D,Bisogni G,Mandich P,Zollino M,Ragozzino E,Udd B,Sabatelli M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The expanded repeat length in ATXN1 negatively correlates with age at onset (AAO) of spinocerebellar ataxia type 1 (SCA1) but can explain only part of it, indicating that other factors affect AAO. Some studies have explored the influence of non-causative CAG repeats on the AAO of SCA patients. Ho...

journal_title：European journal of neurology

authors： Wang P,Chen Z,Peng Y,Cao L,Li X,Wang C,Yang H,Peng H,Shi Y,Zhou X,Li T,Feng L,Wu C,Qiu R,Xia K,Tang B,Jiang H

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis of cytomegalovirus encephalitis (CMV-E) in AIDS patients is challenging as other illnesses may obscure the symptoms. Here, we characterize the clinical symptoms of CMV-E and link them to post-mortem findings. Patients and methods In 254 homosexual men with AIDS, followed from HIV di...

journal_title：European journal of neurology

authors： Pirskanen-Matell R,Grützmeier S,Nennesmo I,Sandström E,Ehrnst A

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:An immune activation response resembling virus or type I interferon responses has been observed in untreated multiple sclerosis (MS), but its pathogenic significance is uncertain. We studied the relationship between a type I interferon-like response in untreated patients with MS and disease activity. METHODS...

journal_title：European journal of neurology

authors： Hesse D,Krakauer M,Lund H,Søndergaard HB,Limborg SJ,Sørensen PS,Sellebjerg F

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The coronavirus disease 2019 (COVID-19) pandemic challenges neurologists in counseling multiple sclerosis (MS) patients with respect to their risk for and by severe acute respiratory syndrome coronavirus 2 and in guiding disease-modifying treatment (DMT). The objective was to determine the freque...

journal_title：European journal of neurology

authors： Bsteh G,Bitschnau C,Hegen H,Auer M,Di Pauli F,Rommer P,Deisenhammer F,Berger T

更新日期：2020-09-25 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticipatory postural adjustments (APAs), prior to step initiation, are bradykinetic in advanced Parkinson's disease (PD) and may be one of the factors associated with 'start hesitation'. However, little is known about APAs in the early stage of PD. In this study, we determined whether body-worn ...

journal_title：European journal of neurology

authors： Mancini M,Zampieri C,Carlson-Kuhta P,Chiari L,Horak FB

更新日期：2009-09-01 00:00:00

abstract：:Mirror movements (MM), involuntary movements of homologous muscles opposite to unilateral limb activity, decrease in the course of motor development, but may reappear in adults after brain damage. To better characterize this type of acquired MM, grip forces of 36 healthy subjects and 35 patients suffering from focal b...

journal_title：European journal of neurology

authors： Uttner I,Mai N,Esslinger O,Danek A

更新日期：2005-12-01 00:00:00

abstract：:Frontotemporal dementia (FTD) often presents with behavioural changes warranting treatment with antipsychotic medications. It is known that patients with Lewy body dementia are sensitive to developing extrapyramidal symptoms (EPS) from these medications. This has not been emphasized in FTD. We report three patients wi...

journal_title：European journal of neurology

authors： Czarnecki K,Kumar N,Josephs KA

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Humanized monoclonal antibody galcanezumab, which binds to calcitonin-gene-related peptide, has shown efficacy for episodic and chronic migraine prevention. These analyses evaluated galcanezumab response for migraine headache prevention in patients who previously failed onabotulinumtoxinA ('nonre...

journal_title：European journal of neurology

authors： Ailani J,Pearlman E,Zhang Q,Nagy AJ,Schuh K,Aurora SK

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Concerning the great importance of brainstem involvement in multiple sclerosis (MS), the aim of this study was to explore the role of the newly developed vestibular evoked myogenic potentials (VEMP) score as a possible marker of brainstem involvement in MS patients. PATIENTS AND METHODS:This was...

journal_title：European journal of neurology

authors： Gabelić T,Krbot Skorić M,Adamec I,Barun B,Zadro I,Habek M

更新日期：2015-02-01 00:00:00

abstract：:The presence of white matter lesions (WML) is an important prognostic factor for the development of stroke. Plasma total homocysteine (tHcy), which increases with diabetes, has been flagged as a novel predictor for cerebrovascular events. We tested the hypothesis that the presence of WML correlates with tHcy and insul...

journal_title：European journal of neurology

authors： Shimomura T,Anan F,Umeno Y,Eshima N,Saikawa T,Yoshimatsu H,Fujiki M,Kobayashi H

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The purpose of the study is to investigate the epidemiology and medical expenses of Wilson's disease in Taiwan. METHODS:Cases of Wilson's disease were identified from the National Health Insurance Research Database with corresponding International Classification of Diseases, Ninth Revision (ICD-9) code 275....

journal_title：European journal of neurology

authors： Lai CH,Tseng HF

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder. Neurological involvement is well-known but cerebral vasculitis and ischaemic stroke are unusual. CASE DESCRIPTION:A 43-year-old male patient presented with acute left hemiparesis, he had recurrent oral aphthae and scrotal ulcerati...

journal_title：European journal of neurology

authors： Krespi Y,Akman-Demir G,Poyraz M,Tugcu B,Coban O,Tuncay R,Serdaroglu P,Bahar S

更新日期：2001-11-01 00:00:00

abstract：:We retrospectively evaluated an elliptic centric ordered 3D (ec 3D) magnetic resonance venography (MRV) technique in comparison to 2D time-of-flight (2D TOF) MRV in patients with presumptive cerebral venous sinus thrombosis (CVST). Twenty-five patients (mean age 40.6 +/- 16.5 years) with presumptive CVST underwent cer...

journal_title：European journal of neurology

authors： Klingebiel R,Bauknecht HC,Bohner G,Kirsch R,Berger J,Masuhr F

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:X-linked dystonia-parkinsonism (XDP) is an inherited neurodegenerative adult-onset movement disorder associated with striatal atrophy. As the dopaminergic system has not yet been systemically studied in this basal ganglia model disease, it is unclear whether nigrostriatal dysfunction contributes ...

journal_title：European journal of neurology

authors： Brüggemann N,Rosales RL,Waugh JL,Blood AJ,Domingo A,Heldmann M,Jamora RD,Münchau A,Münte TF,Lee LV,Buchmann I,Klein C

更新日期：2017-05-01 00:00:00

abstract：:The problem of finding correspondence between a particular neuronal organization and a specific function of the human brain remains a central question of neuroscience. It is sometimes thought that language and music are two sides of the same intellectual coin, but research on brain-damaged patients has shown that the ...

journal_title：European journal of neurology

authors： Amaducci L,Grassi E,Boller F

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia occurs in up to 50% of all patients with acute stroke. There is debate regarding which is the most effective screening tool in identifying aspiration in patients with acute stroke. We assessed the accuracy of the Sapienza Global Bedside Evaluation of Swallowing after Stroke (GLOBE-3S), ...

journal_title：European journal of neurology

authors： Toscano M,Viganò A,Rea A,Verzina A,Sasso D'Elia T,Puledda F,Longo L,Mancini V,Ruggiero M,Jannini TB,Giuliani G,Albino F,Altieri M,Vicenzini E,Fattapposta F,Pauri F,Giacomini P,Ruoppolo G,Di Piero V

更新日期：2019-04-01 00:00:00

abstract：:In recent years, evidence has emerged for a bidirectional relationship between sleep and neurological and psychiatric disorders. First, sleep-wake disorders (SWDs) are very common and may be the first/main manifestation of underlying neurological and psychiatric disorders. Secondly, SWDs may represent an independent r...

journal_title：European journal of neurology

authors： Bassetti CL,Ferini-Strambi L,Brown S,Adamantidis A,Benedetti F,Bruni O,Cajochen C,Dolenc-Groselj L,Ferri R,Gais S,Huber R,Khatami R,Lammers GJ,Luppi PH,Manconi M,Nissen C,Nobili L,Peigneux P,Pollmächer T,Randerath W

更新日期：2015-10-01 00:00:00

abstract：:The objective of this study was to investigate the efficacy, safety and tolerability of triptans in patients who suffer from familial or sporadic hemiplegic migraine. Seventy-six subjects had used triptans at least once as an abortive treatment. Average triptan response was 6.9 (SD +/-3.1) and adverse event severity 4...

journal_title：European journal of neurology

authors： Artto V,Nissilä M,Wessman M,Palotie A,Färkkilä M,Kallela M

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Migraine and metabolic syndrome have been reported to coexist to a marked degree, especially in women migraine patients, but the relationship between these two conditions is still unclear. This study was performed to evaluate the association of headache characteristics and its comorbidities with ...

journal_title：European journal of neurology

authors： He Z,Dong L,Zhang Y,Kong Q,Tan G,Zhou J

更新日期：2015-08-01 00:00:00

abstract：:We report a 69-year-old male patient whose motor aphasia started at the age of 61. The language disability remained isolated and progressed over a period of eight years without any additional cognitive deficits. Computed tomography (CT) and magnetic resonance imaging (MRI) showed moderate cortical atrophy with frontal...

journal_title：European journal of neurology

authors： Nagy TG,Jelencsik I,Szirmai I

更新日期：1999-07-01 00:00:00

abstract：:The Mini-Mental State Examination (MMSE), a brief test to assess cognitive status, is heavily influenced by age and education. It was administered to 1019 elderly subjects (aged 65-89 years) living in three different Italian cities. A statistical non-linear regression model was built up in order to obtain adjustment c...

journal_title：European journal of neurology

authors： Magni E,Binetti G,Bianchetti A,Rozzini R,Trabucchi M

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Several metabolic derangements associated with diabetes mellitus type 2 (DM) have been associated with a better outcome in amyotrophic lateral sclerosis (ALS), including hyperlipidemia and obesity. Here, we tested the hypothesis that DM would have a positive effect on the motor and cognitive findings of ALS....

journal_title：European journal of neurology

authors： Jawaid A,Salamone AR,Strutt AM,Murthy SB,Wheaton M,McDowell EJ,Simpson E,Appel SH,York MK,Schulz PE

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Predicting the course of behavioural variant frontotemporal dementia (bvFTD) remains a major clinical challenge. This study aimed to identify factors that predict survival and clinical progression in bvFTD. METHODS:Consecutive patients with clinically probable bvFTD were prospectively followed u...

journal_title：European journal of neurology

authors： Agarwal S,Ahmed RM,D'Mello M,Foxe D,Kaizik C,Kiernan MC,Halliday GM,Piguet O,Hodges JR

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Myasthenia gravis (MG) is an autoimmune disease caused by antibody mediated impairment in the neuromuscular junction. Seronegative MG (SNMG) without antibodies against acetylcholine receptor (AChR) and muscle-specific kinase (MuSK) by routine assays accounts for about 20% of all MG patients. MET...

journal_title：European journal of neurology

authors： Hong Y,Zisimopoulou P,Trakas N,Karagiorgou K,Stergiou C,Skeie GO,Hao HJ,Gao X,Owe JF,Zhang X,Yue YX,Romi F,Wang Q,Li HF,Gilhus NE,Tzartos SJ

更新日期：2017-06-01 00:00:00

abstract：:The role of genetics and its technological development have been fundamental in advancing the field of movement disorders, opening the door to precision medicine. Starting from the revolutionary discovery of the locus of the Huntington's disease gene, we review the milestones of genetic discoveries in movement disorde...

journal_title：European journal of neurology

authors： Sturchio A,Marsili L,Mahajan A,Grimberg MB,Kauffman MA,Espay AJ

更新日期：2020-08-01 00:00:00

abstract：:Population-based epidemiological studies on epilepsy are available mainly from the UK and the Nordic, Baltic and western Mediterranean countries. No studies were identified from large areas of Europe, especially from the former eastern Europe (except the Baltic countries) and the eastern Mediterranean countries. Based...

journal_title：European journal of neurology

authors： Forsgren L,Beghi E,Oun A,Sillanpää M

更新日期：2005-04-01 00:00:00

abstract：:Post-marketing surveillance studies are needed to assess the long-term safety, compliance and clinical efficacy of interferon beta-1a (IFNbeta-1a) therapy in multiple sclerosis (MS) patients. The goals of this study were to (i) assess the safety, compliance and clinical efficacy of long-term intramuscular (i.m.) IFNbe...

journal_title：European journal of neurology

authors： Coppola G,Lanzillo R,Florio C,Orefice G,Vivo P,Ascione S,Schiavone V,Pagano A,Vacca G,De Michele G,Morra VB

更新日期：2006-09-01 00:00:00

abstract：:We reviewed the magnetic resonance imaging (MRI) database of the Dent Neurologic Institute to study the abnormal findings in myelitis. We identified 22 patients, and compared non-MS-related acute transverse myelitis (ATM, n = 9), to myelitis associated with multiple sclerosis (MS-myelitis, n = 13). The ATM patients we...

journal_title：European journal of neurology

authors： Bakshi R,Kinkel PR,Mechtler LL,Bates VE,Lindsay BD,Esposito SE,Kinkel WR

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS)-related genes and mutations have been increasingly discovered recently and an improved understanding of genotype-phenotype relationships may help to predict the disease course and refine genetic diagnosis. METHODS:We collected clinical data and blood samples f...

journal_title：European journal of neurology

authors： Chen W,Xie Y,Zheng M,Lin J,Huang P,Pei Z,Yao X

更新日期：2020-06-01 00:00:00