Hyperhomocysteinaemia is a significant risk factor for white matter lesions in Japanese type 2 diabetic patients.

abstract：:Polycythemia rubra vera (PRV) is a rare haematological disorder that has a high risk of stroke, although the pathophysiological origin of the cerebral ischaemia in this disease is not well known. We report a case of a stroke patient with PRV in whom bilateral embolic signals were detected by transcranial Doppler (TCD)...

journal_title：European journal of neurology

authors： Segura T,Serena J,Teruel J,Dávalos A

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiological classification of patients with transient ischaemic attack (TIA) is a difficult endeavor and the use of serum biomarkers could improve the diagnostic accuracy. The aim of this study was to correlate atrial fibrillation, the main cardioembolic etiology (CE), with different serum bi...

journal_title：European journal of neurology

authors： Purroy F,Suárez-Luis I,Mauri-Capdevila G,Cambray S,Farré J,Sanahuja J,Piñol-Ripoll G,Quílez A,González-Mingot C,Begué R,Gil MI,Fernández E,Benabdelhak I

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mutations in the glucocerebrosidase (GBA) gene have been implicated in the development of Parkinson's disease (PD). However, recent screenings for GBA mutations in PD subjects from different ethnic populations have yielded contradictory results. METHODS:We performed a case-control study to look ...

journal_title：European journal of neurology

authors： Hu FY,Xi J,Guo J,Yu LH,Liu L,He XH,Liu ZL,Zou XY,Xu YM

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To evaluate the incidence and predictors of ischaemic recurrent stroke and the adverse events of antithrombotic therapy in patients with first intra- or extracranial vertebral artery dissection (VAD) who were treated with aspirin or oral anticoagulation (OA). METHODS:A 21-year database of consec...

journal_title：European journal of neurology

authors： Arauz A,Ruiz A,Pacheco G,Rojas P,Rodríguez-Armida M,Cantú C,Murillo-Bonilla L,Ruiz-Sandoval JL,Barinagarrementeria F

更新日期：2013-01-01 00:00:00

abstract：:At least 13 different disease entities affecting the central nervous system, peripheral nervous system and connective tissue of the skin or kidneys are associated with immunoglobulin G4 (IgG4) immune reactivity. IgG4 has always been considered a benign, non-inflammatory subclass of IgG, in contrast to the well-known c...

journal_title：European journal of neurology

authors： Huijbers MG,Querol LA,Niks EH,Plomp JJ,van der Maarel SM,Graus F,Dalmau J,Illa I,Verschuuren JJ

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulation of iron (Fe) is often detected in brains of people suffering from neurodegenerative diseases. However, no studies have compared the Fe load between these disease entities. The present study investigates by T2*-weighted gradient-echo 7.0 T magnetic resonance imaging (MRI) the Fe conte...

journal_title：European journal of neurology

authors： De Reuck JL,Deramecourt V,Auger F,Durieux N,Cordonnier C,Devos D,Defebvre L,Moreau C,Caparros-Lefebvre D,Leys D,Maurage CA,Pasquier F,Bordet R

更新日期：2014-07-01 00:00:00

abstract：:Histamine has a selective affinity for H3-receptors and it may specifically inhibit the neurogenic edema response involved in migraine pathophysiology. The objective of this study was to evaluate the therapeutic potential of subcutaneous administration of histamine in migraine prophylaxis, compared with oral administr...

journal_title：European journal of neurology

authors： Millán-Guerrero RO,Isais-Millán R,Barreto-Vizcaíno S,Rivera-Castaño L,Garcia-Solorzano A,López-Blanca C,Membrila-Maldonado M,Muñoz-Solis R

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:X-linked dystonia-parkinsonism (XDP) is an inherited neurodegenerative adult-onset movement disorder associated with striatal atrophy. As the dopaminergic system has not yet been systemically studied in this basal ganglia model disease, it is unclear whether nigrostriatal dysfunction contributes ...

journal_title：European journal of neurology

authors： Brüggemann N,Rosales RL,Waugh JL,Blood AJ,Domingo A,Heldmann M,Jamora RD,Münchau A,Münte TF,Lee LV,Buchmann I,Klein C

更新日期：2017-05-01 00:00:00

abstract：:The aim of our study was to analyse clinical and paraclinical characteristics of patients with multiple sclerosis (MS) with previous diagnosis of primary-progressive (PP) MS according to the Poser's criteria and further investigate if they fulfil the McDonald's diagnostic criteria for this disorder. A total of 561 MS ...

journal_title：European journal of neurology

authors： Dujmović I,Mesaros S,Pekmezović T,Lević Z,Drulović J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Impaired cortical inhibiton and maladaptive cortical plasticity are functional hallmarks of sporadic focal dystonias. Whether or not these mechanisms translate to generalized dystonias and whether these features reflect state or trait characteristics are topics of research in hereditary dystonias. METHODS:W...

journal_title：European journal of neurology

authors： Carbon M,Argyelan M,Eidelberg D

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite recent advances in neurogenetics that have facilitated the identification of a number of dystonia genes, many familial dystonia syndromes remain without known cause. The aim of the study was to identify the cause of autosomal dominant tremulous myoclonus-dystonia in a UK kindred with affe...

journal_title：European journal of neurology

authors： Balint B,Guerreiro R,Carmona S,Dehghani N,Latorre A,Cordivari C,Bhatia KP,Bras J

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Botulinum toxin type A (BoNT/A) is a highly effective and well-tolerated treatment for focal dystonias. The BoNT/A in Botox and Dysport is part of a high-molecular-weight complex that contains hemagglutinins and other non-toxic proteins, whilst Xeomin is a highly purified BoNT/A free of such comp...

journal_title：European journal of neurology

authors： Benecke R

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The detection rate of diffusion-weighted (DWI) hyperintense lesions varies widely in patients with transient global amnesia (TGA). The aim was to examine the association of hyperintense lesions on DWI magnetic resonance imaging (MRI) with patient characteristics, precipitating factors, clinical p...

journal_title：European journal of neurology

authors： Higashida K,Okazaki S,Todo K,Sasaki T,Ohara N,Kohara N,Yamamoto S,Yamagami H,Hashikawa K,Yoshimoto T,Ihara M,Koga M,Szabo K,Mochizuki H

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:A Task Force was convened by the EFNS/MDS-ES Scientist Panel on Parkinson's disease (PD) and other movement disorders to systemically review relevant publications on the diagnosis of PD. METHODS:Following the EFNS instruction for the preparation of neurological diagnostic guidelines, recommendation levels h...

journal_title：European journal of neurology

authors： Berardelli A,Wenning GK,Antonini A,Berg D,Bloem BR,Bonifati V,Brooks D,Burn DJ,Colosimo C,Fanciulli A,Ferreira J,Gasser T,Grandas F,Kanovsky P,Kostic V,Kulisevsky J,Oertel W,Poewe W,Reese JP,Relja M,Ruzicka E,Sc

更新日期：2013-01-01 00:00:00

abstract：:We describe a case of transient global amnesia related to symptomatic renal stones. Transient global amnesia has been related to intense emotional or painful experiences, such as sexual intercourse, cold water bathing and trigeminal stimulation. Renal stones may be at the origin of a painful experience and thus may in...

journal_title：European journal of neurology

authors： Kettaneh A,Gobron C,Fain O,Mohib S,Thomas M

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multiple sclerosis (MS) patients discontinuing natalizumab are at risk of rebound of disease activity. METHODS:In the present multi-center, open-label, non-randomized, prospective, pilot study, we tested whether treatment with glatiramer acetate (GA) is safe and effective after natalizumab in MS...

journal_title：European journal of neurology

authors： Rossi S,Motta C,Studer V,De Chiara V,Barbieri F,Monteleone F,Fornasiero A,Coarelli G,Bernardi G,Cutter G,Stüve O,Salvetti M,Centonze D

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subthreshold depression (SubD) is characterized by clinically relevant depressive symptoms not meeting criteria for major depression. The possible association of SubD with subjective cognitive complaints and/or objective cognitive impairments was investigated in a sample of consecutive, non-demen...

journal_title：European journal of neurology

authors： Santangelo G,Vitale C,Trojano L,Angrisano MG,Picillo M,Errico D,Agosti V,Grossi D,Barone P

更新日期：2014-03-01 00:00:00

abstract：:The Oslo Multiple Sclerosis (MS) Registry was established in 1990, and this is the first report on the prevalence and incidence of MS in the city of Oslo, Norway. The prevalence rate of definite MS on 1 January 1995 was 120.4/10(5). Inclusion of patients of native Norwegian ancestry only and exclusion of non-Norwegian...

journal_title：European journal of neurology

authors： Celius EG,Vandvik B

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The clinical predictors of health-related quality of life (HRQoL) in multiple sclerosis (MS) have mainly been studied in patients with long-standing disease. The objective of this study was to investigate the longitudinal association among HRQoL and clinical characteristics in early MS. METHODS:...

journal_title：European journal of neurology

authors： Nourbakhsh B,Julian L,Waubant E

更新日期：2016-09-01 00:00:00

abstract：:Progression of atherosclerosis at extracranial carotid and intracranial arteries in patients with ischemic heart disease (IHD) is not well defined. We carried out a 5-year longitudinal study with magnetic resonance angiography (MRA) of patients with IHD to assess the incidence of progression of atherosclerosis at extr...

journal_title：European journal of neurology

authors： Uehara T,Tabuchi M,Mori E,Yamadori A

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS) is classically assumed to be a neurodegenerative disorder. Inflammation has been observed in CNS tissue in ALS patients. We investigated the expression and prognostic relevance of proinflammatory chemokines in ALS. METHODS:We analyzed nine chemokines, eotaxin,...

journal_title：European journal of neurology

authors： Kuhle J,Lindberg RL,Regeniter A,Mehling M,Steck AJ,Kappos L,Czaplinski A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Peripapillary retinal nerve fibre layer (pRNFL) thickness is a strong candidate as a biomarker of axonal degeneration in multiple sclerosis (MS). The aim was to determine a cut-off value of pRNFL thinning rates in relapsing-remitting MS (RRMS) to discriminate between stable and progressing patien...

journal_title：European journal of neurology

authors： Bsteh G,Hegen H,Teuchner B,Berek K,Wurth S,Auer M,Di Pauli F,Deisenhammer F,Berger T

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder. Neurological involvement is well-known but cerebral vasculitis and ischaemic stroke are unusual. CASE DESCRIPTION:A 43-year-old male patient presented with acute left hemiparesis, he had recurrent oral aphthae and scrotal ulcerati...

journal_title：European journal of neurology

authors： Krespi Y,Akman-Demir G,Poyraz M,Tugcu B,Coban O,Tuncay R,Serdaroglu P,Bahar S

更新日期：2001-11-01 00:00:00

abstract：:We performed a 2-year population-based study on status epilepticus (SE) in adults in the rural area of Lugo di Romagna, northern Italy, to verify whether an area of low-level urbanization has a lower risk of occurrence of SE (as recently suggested), different clinical features and short-term prognosis than areas of hi...

journal_title：European journal of neurology

authors： Vignatelli L,Rinaldi R,Galeotti M,de Carolis P,D'Alessandro R

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia occurs in up to 50% of all patients with acute stroke. There is debate regarding which is the most effective screening tool in identifying aspiration in patients with acute stroke. We assessed the accuracy of the Sapienza Global Bedside Evaluation of Swallowing after Stroke (GLOBE-3S), ...

journal_title：European journal of neurology

authors： Toscano M,Viganò A,Rea A,Verzina A,Sasso D'Elia T,Puledda F,Longo L,Mancini V,Ruggiero M,Jannini TB,Giuliani G,Albino F,Altieri M,Vicenzini E,Fattapposta F,Pauri F,Giacomini P,Ruoppolo G,Di Piero V

更新日期：2019-04-01 00:00:00

abstract：:Most patients with acute disseminated encephalomyelitis (ADEM) recover quickly under corticosteroid treatment and have a favourable long-term prognosis. We report on a young woman with acute onset of an extensive and solitary white-matter lesion in the left hemisphere. Fever, high pleocytosis and elevated protein in c...

journal_title：European journal of neurology

authors： Harloff A,Rauer S,Hofer M,Klisch J,Els T

更新日期：2005-01-01 00:00:00

abstract：:We evaluated the putative factors for the onset of Guillain-Barré syndrome (GBS) in Harbin, China by a case-control study based on the information from GBS patients identified from a population-based incidence survey, which is the first study of this kind in China. Sixty-nine GBS patients were identified during a 1-ye...

journal_title：European journal of neurology

authors： Cheng Q,Wang DS,Jiang GX,Han H,Zhang Y,Wang WZ,Fredrikson S

更新日期：2006-09-01 00:00:00

abstract：:A comprehensive battery of neuropsychological tests sampling a wide range of cognitive functions was administrated to 36 patients with systemic lupus erythematosus (SLE), and a control group consisting of 31 patients with persistent symptoms after whiplash injury. Our results demonstrated significant group differences...

journal_title：European journal of neurology

authors： Waterloo K,Omdal R,Mellgren SI,Husby G

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Polymorphisms of the interleukin-1 (IL-1) gene family have been proposed as potential variants for different diseases including multiple sclerosis (MS). With respect to MS, IL-1 beta (-511 C/T; rs16944), IL-1 beta (+3954 C/T; rs1143634), IL-1 alpha (-889 C/T; rs1800587), IL-1 alpha (+4845 G/T; rs17561), and ...

journal_title：European journal of neurology

authors： Borzani I,Tola MR,Caniatti L,Collins A,De Santis G,Luiselli D,Mamolini E,Scapoli C

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Multiple mitochondrial DNA (mtDNA) deletions usually have a mendelian inheritance secondary to mutation in nuclear genes. One of these is the Twinkle gene whose mutation is responsible for autosomal dominant progressive external ophthalmoplegia (PEO). The number of reported cases with mainly myopathic sympto...

journal_title：European journal of neurology

authors： Martin-Negrier ML,Sole G,Jardel C,Vital C,Ferrer X,Vital A

更新日期：2011-03-01 00:00:00