Primary progressive aphasia: a case report.

abstract：BACKGROUND AND PURPOSE:Peripapillary retinal nerve fibre layer (pRNFL) thickness is a strong candidate as a biomarker of axonal degeneration in multiple sclerosis (MS). The aim was to determine a cut-off value of pRNFL thinning rates in relapsing-remitting MS (RRMS) to discriminate between stable and progressing patien...

journal_title：European journal of neurology

authors： Bsteh G,Hegen H,Teuchner B,Berek K,Wurth S,Auer M,Di Pauli F,Deisenhammer F,Berger T

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The deleterious effect of hyperthermia on intracerebral hemorrhage (ICH) has been studied. However, the results are not conclusive and new studies are needed to elucidate clinical factors that influence the poor outcome. The aim of this study was to identify the clinical factors (including ICH et...

journal_title：European journal of neurology

authors： Iglesias-Rey R,Rodríguez-Yáñez M,Arias S,Santamaría M,Rodríguez-Castro E,López-Dequidt I,Hervella P,Sobrino T,Campos F,Castillo J

更新日期：2018-09-01 00:00:00

abstract：:Treatment outcome in patients with neuropathic pain (NP) is often variable and disappointing. We tested the hypothesis that patients with clear evidence of nervous system lesion respond better to pharmacological treatment with documented effect on NP than patients with poor or no evidence of nervous system lesion. Fur...

journal_title：European journal of neurology

authors： Rasmussen PV,Sindrup SH,Jensen TS,Bach FW

更新日期：2004-08-01 00:00:00

abstract：:Malignancy-related thromboembolism, so-called Trousseau's syndrome, can present as acute cerebral infarction, non-bacterial thrombotic endocarditis (NBTE) and migratory thrombophlebitis. It is usually attributed to a cancer-related hypercoagulable state, chronic disseminated intravascular coagulopathy (DIC), or tumour...

journal_title：European journal of neurology

authors： Tasi SH,Juan CJ,Dai MS,Kao WY

更新日期：2004-07-01 00:00:00

abstract：:We retrospectively evaluated an elliptic centric ordered 3D (ec 3D) magnetic resonance venography (MRV) technique in comparison to 2D time-of-flight (2D TOF) MRV in patients with presumptive cerebral venous sinus thrombosis (CVST). Twenty-five patients (mean age 40.6 +/- 16.5 years) with presumptive CVST underwent cer...

journal_title：European journal of neurology

authors： Klingebiel R,Bauknecht HC,Bohner G,Kirsch R,Berger J,Masuhr F

更新日期：2007-02-01 00:00:00

abstract：:We present the baseline characteristics of 101 patients with normal pressure hydrocephalus (NPH), entering a study that evaluates the diagnostic reliability of CSF outflow resistance. Patients were assessed by a gait scale consisting of 10 features of walking and the number of steps and seconds necessary for 10 m, a d...

journal_title：European journal of neurology

authors： Boon AJ,Tans JT,Delwel EJ,Egeler-Peerdeman SM,Hanlo PW,Wurzer JA,Hermans J

更新日期：1997-01-01 00:00:00

abstract：:Recent studies suggest an association between Chlamydia pneumoniae infection with atherosclerosis, including cerebrovascular disease. We investigated the prevalence of Chlamydial seropositivity in patients with acute ischaemic stroke syndrome compared with age- and sex-matched control subjects. Specific antibodies (Ig...

journal_title：European journal of neurology

authors： Madre JG,Garcia JL,Gonzalez RC,Montero JM,Paniagua EB,Escribano JR,Martinez JD,Cenjor RF

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a distinct epileptic syndrome with a broad range of severity even amongst affected members of the same pedigree, and the level of pharmacoresistance may reach 30%, close to that seen in sporadic focal epilepsies. METHODS:To investiga...

journal_title：European journal of neurology

authors： Labate A,Mumoli L,Fratto A,Quattrone A,Gambardella A

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To evaluate the association between having non-thymoma myasthenia and the risk of extra-thymic cancer in a population-based setting. METHODS:A nationwide case-control study was conducted in Denmark based on medical registries. The study included all cases with a first time diagnosis of cancer du...

journal_title：European journal of neurology

authors： Pedersen EG,Pottegård A,Hallas J,Friis S,Hansen K,Jensen PE,Gaist D

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is an urgent need for early predictive markers for the course of disease in prodromal α-synucleinopathies such as idiopathic rapid eye movement (REM) sleep behaviour disorder. Autonomic cardiac/vascular dysfunction is a prominent feature in advanced α-synucleinopathies, but its diagnostic v...

journal_title：European journal of neurology

authors： Dahms C,Guenther A,Schwab M,Schultze T,Nowack S,Hoyer D,Ehrhardt J,Witte OW,Mayer G,Rupprecht S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS)-related genes and mutations have been increasingly discovered recently and an improved understanding of genotype-phenotype relationships may help to predict the disease course and refine genetic diagnosis. METHODS:We collected clinical data and blood samples f...

journal_title：European journal of neurology

authors： Chen W,Xie Y,Zheng M,Lin J,Huang P,Pei Z,Yao X

更新日期：2020-06-01 00:00:00

abstract：:Levodopa-carbidopa (LD) in low dosages adequately controls symptoms in most patients with Parkinson's disease and delays the appearance of fluctuations and dyskinesias. It has been suggested that early combination therapy with bromocriptine and levodopa delays or prevents the onset of late treatment complication assoc...

journal_title：European journal of neurology

authors： Alarcon F,Cevallos N,Lees AJ

更新日期：1998-05-01 00:00:00

abstract：:Selenium is an essential component of the antioxidant enzyme glutathione peroxidase. The activity of this enzyme is reduced in the substantia nigra of patients with Parkinson's disease (PD), but the results of studies on erythrocytes are controversial. We compared the serum levels of selenium and the 24 h urinary sele...

journal_title：European journal of neurology

authors： Jiménez-Jiménez FJ,Molina JA,Arrieta FJ,Aguilar MV,Cabrera-Valdivia F,Vázquez A,Jorge-Santamaría A,Seijas V,Fernández-Calle P,Martínez-Para MC

更新日期：1995-04-01 00:00:00

abstract：:We describe a patient who, three years after the onset of an olivopontocerebellar atrophy, developed a right cerebral tumour. The cerebellar symptomatology also included, as in other cerebellar patients previously described, a peripheral dysgraphia. Because this deficit of writing is generally reported in patients wit...

journal_title：European journal of neurology

authors： Silveri MC,Misciagna S,Laudisio A,Colosimo C

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticipatory postural adjustments (APAs), prior to step initiation, are bradykinetic in advanced Parkinson's disease (PD) and may be one of the factors associated with 'start hesitation'. However, little is known about APAs in the early stage of PD. In this study, we determined whether body-worn ...

journal_title：European journal of neurology

authors： Mancini M,Zampieri C,Carlson-Kuhta P,Chiari L,Horak FB

更新日期：2009-09-01 00:00:00

abstract：:The role of genetics and its technological development have been fundamental in advancing the field of movement disorders, opening the door to precision medicine. Starting from the revolutionary discovery of the locus of the Huntington's disease gene, we review the milestones of genetic discoveries in movement disorde...

journal_title：European journal of neurology

authors： Sturchio A,Marsili L,Mahajan A,Grimberg MB,Kauffman MA,Espay AJ

更新日期：2020-08-01 00:00:00

abstract：:We report here 39 cases in which definite multiple sclerosis (MS) was precipitated or exacerbated by specific hyperextension-hyperflexion cervical cord trauma. The worsening or onset of the symptomatic disease bore a striking temporal relationship to the focal injury. Our data suggests that central nervous system (CNS...

journal_title：European journal of neurology

authors： Chaudhuri A,Behan PO

更新日期：2001-11-01 00:00:00

abstract：:There is no report of patients in whom pathological laughter, a rare condition characterized by uncontrollable episodes of laughter usually triggered by unrelated stimuli, was ever closely associated with a loss of consciousness overtly linked with the onset of such uncontrollable laughter, also referred to as a gelas...

journal_title：European journal of neurology

authors： Famularo G,Corsi FM,Minisola G,De Simone C,Nicotra GC

更新日期：2007-08-01 00:00:00

abstract：:We reviewed the magnetic resonance imaging (MRI) database of the Dent Neurologic Institute to study the abnormal findings in myelitis. We identified 22 patients, and compared non-MS-related acute transverse myelitis (ATM, n = 9), to myelitis associated with multiple sclerosis (MS-myelitis, n = 13). The ATM patients we...

journal_title：European journal of neurology

authors： Bakshi R,Kinkel PR,Mechtler LL,Bates VE,Lindsay BD,Esposito SE,Kinkel WR

更新日期：1998-01-01 00:00:00

abstract：:Phosphorylated α-synuclein (phosαSYN) containing inclusions in neurons (Lewy bodies, LB) and nerve terminals (Lewy neurites, LN), the pathological hallmark of Parkinson's disease (PD), are not confined to the central nervous system, but have also been reported in peripheral tissues. However, the usefulness of αSYN/pho...

journal_title：European journal of neurology

authors： Schneider SA,Boettner M,Alexoudi A,Zorenkov D,Deuschl G,Wedel T

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Superficial siderosis of the central nervous system is a sporadic finding in magnetic resonance imaging, resulting from recurrent bleedings into the subarachnoid space. This study aimed to determine the frequency of spinal dural cerebrospinal fluid (CSF) leaks amongst patients with a symmetric in...

journal_title：European journal of neurology

authors： Friedauer L,Rezny-Kasprzak B,Steinmetz H,du Mesnil de Rochemont R,Foerch C

更新日期：2020-10-24 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with acute ischemic stroke are at high-risk for contracting COVID-19 infection. Additionally, healthcare professionals including neurovascular ultrasound providers are also at risk of being infected by SARS-CoV-2 virus. Yet, preparedness to continue to guarantee hyperacute treatment is v...

journal_title：European journal of neurology

authors： Baracchini C,Pieroni A,Kneihsl M,Azevedo E,Diomedi M,Pascazio L,Wojczal J,Lucas C,Bartels E,Bornstein NM,Csiba L,Valdueza J,Tsivgoulis G,Malojcic B

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Information about metabolic comorbidities in patients with multiple sclerosis (MS) is scarce. Our aim was to examine the prevalence of the metabolic syndrome (MetS) and its components in patients with long duration of MS and significant disability. METHODS:Demographic and clinical data, weight, ...

journal_title：European journal of neurology

authors： Pinhas-Hamiel O,Livne M,Harari G,Achiron A

更新日期：2015-09-01 00:00:00

abstract：:The activities of the metalloproteinase gelatinase B, and the presence of IL-6, an inducer of metalloproteinase inhibitors, were investigated in CSF samples of 190 patients with multiple sclerosis (MS; n = 55), optic neuritis (ON; n = 46), other inflammatory neurological diseases (OIND; n = 27) or control patients (CO...

journal_title：European journal of neurology

authors： Paemen L,Olsson T,Söderström M,van Damme J,Opdenakker G

更新日期：1994-09-01 00:00:00

abstract：:Astasia, inability to stand unsupported despite good strength, resembles the marked balance impairment of patients with vestibulocerebellar disease. We describe a patient with unilateral thalamic infarct that presented with astasia. A 76-year-old hypertensive woman was admitted to our hospital because of marked unstea...

journal_title：European journal of neurology

authors： Lee PH,Lee JH,Joo US

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Spastic pes equinovarus is a frequent pathological posture of the lower extremity. Botulinum toxin (BoNT/A) has been successfully applied to treat lower limb spasticity. However, the best time to initiate treatment remains unclear. A beneficial effect of an early treatment has been suggested in p...

journal_title：European journal of neurology

authors： Fietzek UM,Kossmehl P,Schelosky L,Ebersbach G,Wissel J

更新日期：2014-08-01 00:00:00

abstract：:Autosomal dominant cerebellar ataxias (ADCAs) are a complex group of slowly progressive neurodegenerative disorders characterized by gait and stance ataxia, dysarthria and other symptoms of nervous system involvement. ADCA type I is the commonest form and is genetically heterogeneous; several loci have been identified...

journal_title：European journal of neurology

authors： Giuffrida S,Lanza S,Restivo DA,Saponara R,Valvo SC,Le Pira F,Trovato Salinaro A,Spinella F,Nicoletti A,Condorelli DF

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A transient ischemic attack (TIA) can occur without self-awareness of symptoms. We aimed to investigate characteristics of patients with a tissue-based diagnosis of TIA but having no self-awareness of their symptoms and whose symptoms were witnessed by bystanders. METHODS:We used data from the m...

journal_title：European journal of neurology

authors： Tanaka K,Uehara T,Ohara T,Sato S,Hayakawa M,Kimura K,Okada Y,Hasegawa Y,Tanahashi N,Suzuki A,Nakagawara J,Arii K,Nagahiro S,Ogasawara K,Uchiyama S,Matsumoto M,Iihara K,Toyoda K,Minematsu K,PROMISE-TIA study Investig

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to analyse the long-term impact of Guillain-Barré syndrome (GBS) on quality of life, and the relationship between clinical variables at disease onset and symptoms at follow-up to general health status. METHODS:Forty-two GBS patients were examined at median 6 years a...

journal_title：European journal of neurology

authors： Rudolph T,Larsen JP,Farbu E

更新日期：2008-12-01 00:00:00

abstract：:An alanin-9valin (Ala-9Val) polymorphism in the mitochondrial targeting sequence of manganese-containing superoxide dismutase (Mn-SOD) has recently been described. We studied this polymorphism in 72 Swedish patients with sporadic motor neuron diseases (MND) and controls using an oligonucleotide ligation assay. There w...

journal_title：European journal of neurology

authors： Van Landeghem GF,Tabatabaie P,Beckman G,Beckman L,Andersen PM

更新日期：1999-11-01 00:00:00