Heritability of young- and old-onset ischaemic stroke.

abstract：BACKGROUND AND PURPOSE:Although Labrune syndrome is a well-known disorder characterized by a typical neuroradiological triad, namely leukoencephalopathy, intracranial calcifications and cysts, there are no reports of systemic involvement in this disorder. This paper attempts to describe a peculiar clinical manifestatio...

journal_title：European journal of neurology

authors： Bonomo G,Monfrini E,Borellini L,Bonomo R,Arienti F,Saetti MC,Di Fonzo A,Locatelli M

更新日期：2020-11-01 00:00:00

abstract：:Autoantibodies in patients with paraneoplastic neurological syndromes (PNS) have been reported to be predominantly IgG1 and IgG3 isotypes. However, no data are available about the IgG subclass distribution of the total serum IgG in these patients. Therefore, we investigated the IgG subclass distribution (given as perc...

journal_title：European journal of neurology

authors： Blaes F,Klotz M,Funke D,Strittmatter M,Kraus J,Kaps M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The association between vascular risk factors and dementia is of interest. Several studies have shown that cerebral small vessel disease (SVD) is associated with dementia. However, the association between cerebral large vessel disease (LVD) and dementia has not been thoroughly examined. METHODS:...

journal_title：European journal of neurology

authors： Kitagawa K,Miwa K,Yagita Y,Okazaki S,Sakaguchi M,Mochizuki H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To examine the relative risk (RR) for living in nursing homes for patients with Parkinson's disease (PD) compared with the general population and to ascertain society's costs related to nursing home placement for this patient group. METHODS:We evaluated the frequency of admission to nursing home...

journal_title：European journal of neurology

authors： Vossius C,Nilsen OB,Larsen JP

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:McLeod neuroacanthocytosis syndrome (MLS) is an X-linked multisystem disorder with CNS manifestations resembling Huntington disease. Neuroimaging studies revealed striatal atrophy with predominance of the caudate nucleus. Our previous cross-sectional MRI study showed an association of volume loss...

journal_title：European journal of neurology

authors： Valko PO,Hänggi J,Meyer M,Jung HH

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Frontotemporal dementia (FTD) is a degenerative disorder characterized, in its frontal variant, by psychiatric onset, deficits in executive functions and sparing of memory and visuo-spatial abilities. Studies on visuo-spatial abilities in FTD and Alzheimer's disease (AD) have mainly focused on co...

journal_title：European journal of neurology

authors： Gasparini M,Masciarelli G,Vanacore N,Ottaviani D,Salati E,Talarico G,Lenzi GL,Bruno G

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A transient ischemic attack (TIA) can occur without self-awareness of symptoms. We aimed to investigate characteristics of patients with a tissue-based diagnosis of TIA but having no self-awareness of their symptoms and whose symptoms were witnessed by bystanders. METHODS:We used data from the m...

journal_title：European journal of neurology

authors： Tanaka K,Uehara T,Ohara T,Sato S,Hayakawa M,Kimura K,Okada Y,Hasegawa Y,Tanahashi N,Suzuki A,Nakagawara J,Arii K,Nagahiro S,Ogasawara K,Uchiyama S,Matsumoto M,Iihara K,Toyoda K,Minematsu K,PROMISE-TIA study Investig

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The clinical predictors of health-related quality of life (HRQoL) in multiple sclerosis (MS) have mainly been studied in patients with long-standing disease. The objective of this study was to investigate the longitudinal association among HRQoL and clinical characteristics in early MS. METHODS:...

journal_title：European journal of neurology

authors： Nourbakhsh B,Julian L,Waubant E

更新日期：2016-09-01 00:00:00

abstract：:We examined the peripheral-central sensory conduction by using somatosensory evoked potential (SEP) in a 48 year old diabetic patient with acute painful neuropathy. The sural, ulnar and median sensory nerve conduction and SEP elicited by wrist stimulation showed no abnormalities, nevertheless, the tibial nerve SEP rev...

journal_title：European journal of neurology

authors： Shimamura H,Baba M,Ozaki I,Matsunaga M,Onuma T

更新日期：1996-05-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic and potentially highly disabling disorder with considerable social impact and economic consequences. It is the major cause of non-traumatic disability in young adults. The social costs associated with MS are high because of its long duration, the early loss of productivity, the nee...

journal_title：European journal of neurology

authors： Pugliatti M,Rosati G,Carton H,Riise T,Drulovic J,Vécsei L,Milanov I

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS) is classically assumed to be a neurodegenerative disorder. Inflammation has been observed in CNS tissue in ALS patients. We investigated the expression and prognostic relevance of proinflammatory chemokines in ALS. METHODS:We analyzed nine chemokines, eotaxin,...

journal_title：European journal of neurology

authors： Kuhle J,Lindberg RL,Regeniter A,Mehling M,Steck AJ,Kappos L,Czaplinski A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subthreshold depression (SubD) is characterized by clinically relevant depressive symptoms not meeting criteria for major depression. The possible association of SubD with subjective cognitive complaints and/or objective cognitive impairments was investigated in a sample of consecutive, non-demen...

journal_title：European journal of neurology

authors： Santangelo G,Vitale C,Trojano L,Angrisano MG,Picillo M,Errico D,Agosti V,Grossi D,Barone P

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mutations in the glucocerebrosidase (GBA) gene have been implicated in the development of Parkinson's disease (PD). However, recent screenings for GBA mutations in PD subjects from different ethnic populations have yielded contradictory results. METHODS:We performed a case-control study to look ...

journal_title：European journal of neurology

authors： Hu FY,Xi J,Guo J,Yu LH,Liu L,He XH,Liu ZL,Zou XY,Xu YM

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:For Parkinson's disease (PD), an extended-release (ER) pramipexole formulation taken once daily, has shown efficacy, safety, and tolerability resembling those of immediate-release (IR) pramipexole taken three times daily. The present study assessed, in advanced PD, the success of an overnight swi...

journal_title：European journal of neurology

authors： Schapira AH,Barone P,Hauser RA,Mizuno Y,Rascol O,Busse M,Debieuvre C,Fraessdorf M,Poewe W

更新日期：2013-01-01 00:00:00

abstract：:To establish the phenotypic variation and frequency of SPAST mutations or deletions in Norwegian patients with hereditary spastic paraplegia (HSP), we examined 59 unrelated patients with HSP and screened for DNA point mutations and microdeletions in SPG4. Forty-one had a familial history, 35 had a clear dominant inher...

journal_title：European journal of neurology

authors： Erichsen AK,Inderhaug E,Mattingsdal M,Eiklid K,Tallaksen CM

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The ataxias are a challenging group of neurological diseases due the aetiological heterogeneity and the complexity of the genetic subtypes. This guideline focuses on the heredodegenerative ataxias. The aim is to provide a peer-reviewed evidence-based guideline for clinical neurologists and oth...

journal_title：European journal of neurology

authors： van de Warrenburg BP,van Gaalen J,Boesch S,Burgunder JM,Dürr A,Giunti P,Klockgether T,Mariotti C,Pandolfo M,Riess O

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Conversion disorder (CD), or functional neurological disorder, is manifested as a neurological disturbance that is not macroscopically visible on clinical structural neuroimaging and is instead ascribed to underlying psychological stress. Known for many years in neuropsychiatry, a comprehensive e...

journal_title：European journal of neurology

authors： Monsa R,Peer M,Arzy S

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Charcot-Marie-Tooth (CMT) disease is a chronic, slowly progressing disorder. The lack of specific disease progression biomarkers limits the execution of clinical trials. However, neurofilament light chain (NfL) has been suggested as a potential biomarker for peripheral nervous system disorders. ...

journal_title：European journal of neurology

authors： Millere E,Rots D,Simrén J,Ashton NJ,Kupats E,Micule I,Priedite V,Kurjane N,Blennow K,Gailite L,Zetterberg H,Kenina V

更新日期：2020-12-19 00:00:00

abstract：BACKGROUND AND PURPOSE:Non-Western immigrants to Norway acquire an increased risk of multiple sclerosis (MS) after migration. Ethnicity and the presence of oligoclonal bands (OCBs) in the cerebrospinal fluid (CSF) might influence the disease course. The aim of this study was to investigate differences in disease severi...

journal_title：European journal of neurology

authors： Berg-Hansen P,Smestad C,Sandvik L,Harbo HF,Celius EG

更新日期：2013-12-01 00:00:00

abstract：:Treadmill training with partial body weight support can restore the gait ability of chronic non-ambulatory hemiparetic subjects. A combination of physiotherapy and treadmill training may accelerate the rate of recovery. Therefore a randomized study was planned. Twenty-eight non-ambulatory hemiparetic patients were ran...

journal_title：European journal of neurology

authors： Werner C,Bardeleben A,Mauritz KH,Kirker S,Hesse S

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Superficial siderosis of the central nervous system is a sporadic finding in magnetic resonance imaging, resulting from recurrent bleedings into the subarachnoid space. This study aimed to determine the frequency of spinal dural cerebrospinal fluid (CSF) leaks amongst patients with a symmetric in...

journal_title：European journal of neurology

authors： Friedauer L,Rezny-Kasprzak B,Steinmetz H,du Mesnil de Rochemont R,Foerch C

更新日期：2020-10-24 00:00:00

abstract：:Phosphorylated α-synuclein (phosαSYN) containing inclusions in neurons (Lewy bodies, LB) and nerve terminals (Lewy neurites, LN), the pathological hallmark of Parkinson's disease (PD), are not confined to the central nervous system, but have also been reported in peripheral tissues. However, the usefulness of αSYN/pho...

journal_title：European journal of neurology

authors： Schneider SA,Boettner M,Alexoudi A,Zorenkov D,Deuschl G,Wedel T

更新日期：2016-02-01 00:00:00

abstract：:We evaluated the cerebral hemodynamic features of severe bilateral carotid stenosis by assessing and comparing cerebral vasomotor reactivity (VMR) in the middle cerebral (MCA) and vertebral arteries (VA) by transcranial Doppler and the Diamox (1 g acetazolamide i.v.) test. VMR was evaluated by recording the percentage...

journal_title：European journal of neurology

authors： Gur AY,Bornstein NM

更新日期：2006-02-01 00:00:00

abstract：:There are about 25.7 million stroke survivors worldwide. Ischaemic stroke remains the most common type of stroke. Numerous modifiable risk factors have been identified, including behaviors such as cigarette smoking and sedentary lifestyle and treatable medical comorbidities such as hypertension, hyperlipidemia and atr...

journal_title：European journal of neurology

authors： Meschia JF,Brott T

更新日期：2018-01-01 00:00:00

abstract：:Botulinum A toxin (BT) has been successfully used for the management of spasticity in cerebral palsy (CP). However, the long-term results of BT have not yet been determined. We have studied the evolution of a homogeneous group of patients with CP treated with BT. All these patients had an equinus gait resulting from c...

journal_title：European journal of neurology

authors： García Ruiz PJ,Pascual Pascual I,Sánchez Bernardos V

更新日期：2000-03-01 00:00:00

abstract：:We describe a patient who, three years after the onset of an olivopontocerebellar atrophy, developed a right cerebral tumour. The cerebellar symptomatology also included, as in other cerebellar patients previously described, a peripheral dysgraphia. Because this deficit of writing is generally reported in patients wit...

journal_title：European journal of neurology

authors： Silveri MC,Misciagna S,Laudisio A,Colosimo C

更新日期：2000-05-01 00:00:00

abstract：:Malignancy-related thromboembolism, so-called Trousseau's syndrome, can present as acute cerebral infarction, non-bacterial thrombotic endocarditis (NBTE) and migratory thrombophlebitis. It is usually attributed to a cancer-related hypercoagulable state, chronic disseminated intravascular coagulopathy (DIC), or tumour...

journal_title：European journal of neurology

authors： Tasi SH,Juan CJ,Dai MS,Kao WY

更新日期：2004-07-01 00:00:00

abstract：:Intracranial internal carotid artery (ICA) aneurysms are frequently treated either by microsurgical clipping of the aneurysm neck, by endovascular coiling of the aneurysm sac or by balloon occlusion of the parent vessel. For some broad-based aneurysms that may not be suitable for any of these options, microsurgical wr...

journal_title：European journal of neurology

authors： Berger C,Hartmann M,Wildemann B

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischaemic stroke frequently has a cardioembolic (CE) source. Clinical and echocardiographic parameters associated with CE stroke were evaluated. METHODS:In all, 93 consecutive ischaemic stroke patients who underwent a transthoracic echocardiogram were retrospectively analysed; strokes were class...

journal_title：European journal of neurology

authors： Ferkh A,Brown P,O'Keefe E,Zada M,Duggins A,Thiagalingam A,Altman M,Boyd A,Byth K,Kizana E,Denniss AR,Thomas L

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of cardiovascular risk factors in the pathogenesis of cognitive impairment and dementia remains still unclear. We examined the impact of cardiovascular risk factors on cognitive function in a large longitudinal population study. METHODS:Subjects were 5033 stroke-free men and women who p...

journal_title：European journal of neurology

authors： Arntzen KA,Schirmer H,Wilsgaard T,Mathiesen EB

更新日期：2011-05-01 00:00:00