Clinical and echocardiographic characteristics of cardioembolic stroke.

abstract：BACKGROUND AND PURPOSE:The expanded repeat length in ATXN1 negatively correlates with age at onset (AAO) of spinocerebellar ataxia type 1 (SCA1) but can explain only part of it, indicating that other factors affect AAO. Some studies have explored the influence of non-causative CAG repeats on the AAO of SCA patients. Ho...

journal_title：European journal of neurology

authors： Wang P,Chen Z,Peng Y,Cao L,Li X,Wang C,Yang H,Peng H,Shi Y,Zhou X,Li T,Feng L,Wu C,Qiu R,Xia K,Tang B,Jiang H

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is an urgent need for early predictive markers for the course of disease in prodromal α-synucleinopathies such as idiopathic rapid eye movement (REM) sleep behaviour disorder. Autonomic cardiac/vascular dysfunction is a prominent feature in advanced α-synucleinopathies, but its diagnostic v...

journal_title：European journal of neurology

authors： Dahms C,Guenther A,Schwab M,Schultze T,Nowack S,Hoyer D,Ehrhardt J,Witte OW,Mayer G,Rupprecht S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The association between vascular risk factors and dementia is of interest. Several studies have shown that cerebral small vessel disease (SVD) is associated with dementia. However, the association between cerebral large vessel disease (LVD) and dementia has not been thoroughly examined. METHODS:...

journal_title：European journal of neurology

authors： Kitagawa K,Miwa K,Yagita Y,Okazaki S,Sakaguchi M,Mochizuki H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Cardiac (123) I-metaiodobenzylguanidine ((123) I-MIBG) uptake in patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) is markedly reduced, as in Parkinson's disease (PD). METHODS:We performed (123) I-MIBG scintigrams on patients with iRBD and PD. After the initial (123) I-MIBG sc...

journal_title：European journal of neurology

authors： Miyamoto T,Miyamoto M,Iwanami M,Hirata K

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Pre-treatment with antiplatelet agents (AP) is present amongst 30% of acute stroke patients. Previous studies have shown conflicting results on the effect of these drugs regarding haemorrhagic transformation after thrombolytic therapy. The hypothesis that pre-treatment with AP may increase the risk of cerebr...

journal_title：European journal of neurology

authors： Dorado L,Millán M,de la Ossa NP,Guerrero C,Gomis M,López-Cancio E,Ricciardi AC,Dávalos A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anosognosia refers to a deficit of self-awareness or impaired insight for cognitive and behavioral problems. Cognitive anosognosia was explored in de novo patients with Parkinson's disease (PD) and its relationship to cognitive function and neuropsychiatric symptoms was investigated. METHODS:The...

journal_title：European journal of neurology

authors： Yoo HS,Chung SJ,Lee YH,Ye BS,Sohn YH,Lee PH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In multiple sclerosis (MS), disease-related factors and dysfunctional coping might favor the development of mental distress induced by COVID-19 containment measures. Aim of this study was exploring the relationship between disability, coping strategies, daily life reorganization and neuropsychiat...

journal_title：European journal of neurology

authors： Costabile T,Carotenuto A,Lavorgna L,Borriello G,Moiola L,Inglese M,Petruzzo M,Trojsi F,Ianniello A,Nozzolillo A,Cellerino M,Boffa G,Rosa L,Servillo G,Moccia M,Bonavita S,Filippi M,Lanzillo R,Brescia Morra V,Petracca

更新日期：2020-10-11 00:00:00

abstract：BACKGROUND:Depigmentation of the substantia nigra (SN) and locus coeruleus (LC) is a conspicuous pathological feature of Parkinson's disease (PD) and is related to the loss of neuromelanin, whose paramagnetic properties result in high signal on specific T1-weighted magnetic resonance imaging (MRI). Recent studies have ...

journal_title：European journal of neurology

authors： Reimão S,Pita Lobo P,Neutel D,Correia Guedes L,Coelho M,Rosa MM,Ferreira J,Abreu D,Gonçalves N,Morgado C,Nunes RG,Campos J,Ferreira JJ

更新日期：2015-03-01 00:00:00

abstract：:In the present study we have explored antigliadin (AGA) and antireticulin (ARA) antibody tests for the serological screening for coeliac disease (CD) of 206 children with neurological disorders. IgA- or/and IgG-type AGA was discovered in 17 (8.3%) patients and IgA-type ARA in one (0.5%) patient. A small intestinal bio...

journal_title：European journal of neurology

authors： Salur L,Uibo O,Talvik I,Justus I,Metsküla K,Talvik T,Uibo R

更新日期：2000-11-01 00:00:00

abstract：:In recent years, a number of potential new therapeutic indications of botulinum toxin injections have emerged, amongst which sialorrhea has attracted considerable attention. Based on open-label and controlled studies, botulinum toxin can be used to improve sialorrhea in patients with Parkinson's disease, parkinsonian ...

journal_title：European journal of neurology

authors： Tan EK

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Dopamine is an important neurotransmitter in the regulation of the sleep-wake cycle, and parkinsonian patients suffer from prominent sleep abnormalities. Hence, the question arises whether the disrupted sleep pattern in Parkinson's disease (PD) is responsive to dopaminergic treatment. METHODS:Thirty-two pat...

journal_title：European journal of neurology

authors： Wailke S,Herzog J,Witt K,Deuschl G,Volkmann J

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dermatomyositis (DM) with anti-nuclear matrix protein-2 (NXP-2) antibodies usually shows multifocal ischaemic lesions in muscle. Here, we aimed to investigate the microarteriopathy underlying muscle ischaemia in anti-NXP-2-positive DM. METHODS:A total of 16 patients diagnosed with anti-NXP-2-pos...

journal_title：European journal of neurology

authors： Liu Y,Zheng Y,Gang Q,Xie Z,Jin Y,Zhang X,Deng X,Hao H,Gao F,Zhang Z,Xiong H,Zhang W,Wang Z,Yuan Y

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Whether the neuromelanin-positive substantia nigra pars compacta area (NM-SNc) on neuromelanin magnetic resonance imaging (NM-MRI) and the specific binding ratio (SBR) on 123 I-N-v-fluoropropyl-2b-carbomethoxy3b-(4-iodophenyl)nortropane single photon emission computed tomography (DaT-SPECT) can b...

journal_title：European journal of neurology

authors： Okuzumi A,Hatano T,Kamagata K,Hori M,Mori A,Oji Y,Taniguchi D,Daida K,Shimo Y,Yanagisawa N,Nojiri S,Aoki S,Hattori N

更新日期：2019-11-01 00:00:00

abstract：:Normal subjects use an open-loop motor control strategy in handwriting, but they are able to switch to closed-loop motor control when the demands on accuracy increase. These closed-loop handwriting movements of normal subjects resemble the inefficient movements found in writing-impaired patients. The hypothesis that s...

journal_title：European journal of neurology

authors： Schenk T,Walther EU,Mai N

更新日期：2000-05-01 00:00:00

abstract：:High socioeconomic status (SES) is generally associated with better health outcomes, but some research has linked it with an increased risk of multiple sclerosis (MS). The evidence for this association is inconsistent and has not previously been systematically reviewed. A systematic review of cohort and case-control s...

journal_title：European journal of neurology

authors： Goulden R,Ibrahim T,Wolfson C

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:A Task Force was convened by the EFNS/MDS-ES Scientist Panel on Parkinson's disease (PD) and other movement disorders to systemically review relevant publications on the diagnosis of PD. METHODS:Following the EFNS instruction for the preparation of neurological diagnostic guidelines, recommendation levels h...

journal_title：European journal of neurology

authors： Berardelli A,Wenning GK,Antonini A,Berg D,Bloem BR,Bonifati V,Brooks D,Burn DJ,Colosimo C,Fanciulli A,Ferreira J,Gasser T,Grandas F,Kanovsky P,Kostic V,Kulisevsky J,Oertel W,Poewe W,Reese JP,Relja M,Ruzicka E,Sc

更新日期：2013-01-01 00:00:00

abstract：:Visual system dysfunction has been reported in Parkinson's disease (PD). The objective of the present study was to evaluate a putative association of distorted colour vision and delayed initiation and execution of movement in PD. We performed the Farnsworth-Munsell 100-hue test and estimated the total error score in 3...

journal_title：European journal of neurology

authors： Müller T,Kuhn W,Büttner T,Przuntek H

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dimethyl fumarate (DMF) causes a mean lymphocyte count drop of approximately 30% in relapsing-remitting multiple sclerosis (RRMS) patients. The relationship between this reduction and DMF effectiveness is controversial. The objective was to investigate if the decrease in absolute lymphocyte count...

journal_title：European journal of neurology

authors： Tsantes E,Curti E,Ferraro D,Lugaresi A,Baldi E,Montepietra S,Immovilli P,Simone AM,Mancinelli L,Strumia S,Vitetta F,Foschi M,Ferri C,Ferrarini C,Sola P,Granella F

更新日期：2021-01-01 00:00:00

abstract：:A PARK8 form of Parkinson's disease (PD) is caused by a novel gene, leucine-rich repeat kinase 2 (LRRK2), and a single mutation G2019S was found in a proportion of LRRK2-associated cases of diverse ethnic origins. We performed the LRRK2 G2019S mutation analysis in 304 Russian patients with PD, including 291 sporadic a...

journal_title：European journal of neurology

authors： Illarioshkin SN,Shadrina MI,Slominsky PA,Bespalova EV,Zagorovskaya TB,Bagyeva GKh,Markova ED,Limborska SA,Ivanova-Smolenskaya IA

更新日期：2007-04-01 00:00:00

abstract：:The aim of this narrative review is to evaluate the pathogenesis, clinical features, diagnosis, treatment and prognosis of intracranial artery dissection (IAD). IAD is a rare and often unrecognized cause of stroke or subarachnoid haemorrhage (SAH), especially in young adults. Two types of IAD can be identified: a subi...

journal_title：European journal of neurology

authors： Sikkema T,Uyttenboogaart M,Eshghi O,De Keyser J,Brouns R,van Dijk JM,Luijckx GJ

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our study aims to evaluate retinal function and neural conduction in post-retinal visual pathways of patients with non-arteritic ischaemic optic neuropathy (NION). METHODS:Twenty patients (mean age: 63.7 +/- 5.96 year) with NION and 20 age-similar control subjects were enrolled. Simultaneous rec...

journal_title：European journal of neurology

authors： Parisi V,Gallinaro G,Ziccardi L,Coppola G

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Since the outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, several reports indicated neurological involvement in COVID-19 disease. Muscle involvement has also been reported as evidenced by creatine kinase (CK) elevations and reports of myalgia. METHODS:Creat...

journal_title：European journal of neurology

authors： Pitscheider L,Karolyi M,Burkert FR,Helbok R,Wanschitz JV,Horlings C,Pawelka E,Omid S,Traugott M,Seitz T,Zoufaly A,Lindeck-Pozza E,Wöll E,Beer R,Seiwald S,Bellmann-Weiler R,Hegen H,Löscher WN

更新日期：2020-09-30 00:00:00

abstract：:A previous study in subjects with focal dystonia suggested that the greater and longer-lasting effect induced by botulinum toxin type A (BoNT-A) on the tonic vibration reflex (TVR) than on the maximal M-wave (M-max) might be the physiological marker of the toxin's action at the level of intrafusal muscle fibres. With ...

journal_title：European journal of neurology

authors： Trompetto C,Bove M,Avanzino L,Francavilla G,Berardelli A,Abbruzzese G

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Investigations on cause of death may provide valuable information about life expectancy and on conditions of terminal dementia care, which perhaps can be ameliorated. METHODS:The autopsy reports were studied on all patients (n = 524; 55.3% females; median age 80 years) with a clinically and neuropathologica...

journal_title：European journal of neurology

authors： Brunnström HR,Englund EM

更新日期：2009-04-01 00:00:00

abstract：:Urinary dysfunction is very common in idiopathic Parkinson's disease (PD) and manifests primarily with symptoms of overactive bladder (OAB). Affection of central serotonergic systems has been suggested to play a role in OAB. The objective of this study was to evaluate whether in PD patients with OAB symptoms a specifi...

journal_title：European journal of neurology

authors： Walter U,Dressler D,Wolters A,Wittstock M,Benecke R

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Blood pressure (BP) levels in acute intracerebral hemorrhage (ICH) and mortality have not been thoroughly studied in the young. METHODS:The relationship between BP and mortality was assessed in consecutive patients with first-ever, non-traumatic acute ICH at ≤50 years of age, enrolled in the Hel...

journal_title：European journal of neurology

authors： Mustanoja S,Putaala J,Koivunen RJ,Surakka I,Tatlisumak T

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We previously reported that certain optical coherence tomography (OCT) measures were sensitive and reliable in identifying idiopathic intracranial hypertension (IIH). This prospective study aimed to define OCT measures that allow differentiation of IIH with and without papilledema, thereby helpin...

journal_title：European journal of neurology

authors： Huang-Link Y,Eleftheriou A,Yang G,Johansson JM,Apostolou A,Link H,Jin YP

更新日期：2019-05-01 00:00:00

abstract：:To establish the phenotypic variation and frequency of SPAST mutations or deletions in Norwegian patients with hereditary spastic paraplegia (HSP), we examined 59 unrelated patients with HSP and screened for DNA point mutations and microdeletions in SPG4. Forty-one had a familial history, 35 had a clear dominant inher...

journal_title：European journal of neurology

authors： Erichsen AK,Inderhaug E,Mattingsdal M,Eiklid K,Tallaksen CM

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Quantification of intraepidermal nerve fibers (IENFs) in skin biopsies is now the tool of choice to diagnose small fiber neuropathies. An adequate normative dataset, necessary to assess normality cutoffs, is available for brightfield microscopy but not for immunofluorescence. METHODS:Intraepider...

journal_title：European journal of neurology

authors： Provitera V,Gibbons CH,Wendelschafer-Crabb G,Donadio V,Vitale DF,Stancanelli A,Caporaso G,Liguori R,Wang N,Santoro L,Kennedy WR,Nolano M

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CACNA1S encodes Cav 1.1, a voltage sensor for muscle excitation-contraction coupling, which activates the ryanodine receptor 1 (RYR1) leading to calcium release from the sarcoplasmic reticulum. CACNA1S mutations cause hypokalemic periodic paralysis, malignant hyperthermia and congenital myopathy....

journal_title：European journal of neurology

authors： Anandan C,Cipriani MA,Laughlin RS,Niu Z,Milone M

更新日期：2018-02-01 00:00:00