Effect of controlled-release levodopa on the microstructure of sleep in Parkinson's disease.

abstract：:In the international neurological literature, neuroimaging research plays an important role. Neuroimaging techniques are also of steadily increasing importance for clinical diagnosis and treatment monitoring. Therefore, neuroimaging research activities were surveyed by a questionnaire, which was completed by 100 neuro...

journal_title：European journal of neurology

authors： Herholz K,Perani D,Fazekas F,Markus H,Baumgartner RW,Baron JC

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Screening batteries to narrow down a target-at-risk population are essential for trials testing neuroprotective compounds aiming to delay or prevent onset of Parkinson's disease (PD). METHODS:The PRIPS study focuses on early detection of incident PD in 1847 at baseline PD-free subjects, and asse...

journal_title：European journal of neurology

authors： Berg D,Godau J,Seppi K,Behnke S,Liepelt-Scarfone I,Lerche S,Stockner H,Gaenslen A,Mahlknecht P,Huber H,Srulijes K,Klenk J,Fassbender K,Maetzler W,Poewe W,PRIPS study group.

更新日期：2013-01-01 00:00:00

abstract：:A recently symptomatic carotid artery stenosis carries a high risk of subsequent ischaemic events and thus requires rapid treatment. We investigated the influence of the time delay between the last symptomatic event of a carotid stenosis and subsequent carotid artery stenting (CAS) with respect to the combined 30-day ...

journal_title：European journal of neurology

authors： Gröschel K,Knauth M,Ernemann U,Pilgram SM,Schnaudigel S,Kastrup A

更新日期：2008-01-01 00:00:00

abstract：:We studied specific aspects of speed performance in neuropsychological tests and functional and vocational long-term outcome among moderate or severe traumatic brain injury (TBI) patients admitted to a rehabilitation programme. A group of 140 patients with mild, moderate or severe TBI was followed up for a minimum of ...

journal_title：European journal of neurology

authors： Asikainen I,Nybo T,Muller K,Sarna S,Kaste M

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To assess the efficacy and safety of olesoxime, a molecule with neuroprotective properties, in patients with amyotrophic lateral sclerosis (ALS) treated with riluzole. METHODS:A double-blind, randomized, placebo-controlled, multicenter trial of 18 months' duration was conducted in 512 subjects, ...

journal_title：European journal of neurology

authors： Lenglet T,Lacomblez L,Abitbol JL,Ludolph A,Mora JS,Robberecht W,Shaw PJ,Pruss RM,Cuvier V,Meininger V,Mitotarget study group.

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is an urgent need for early predictive markers for the course of disease in prodromal α-synucleinopathies such as idiopathic rapid eye movement (REM) sleep behaviour disorder. Autonomic cardiac/vascular dysfunction is a prominent feature in advanced α-synucleinopathies, but its diagnostic v...

journal_title：European journal of neurology

authors： Dahms C,Guenther A,Schwab M,Schultze T,Nowack S,Hoyer D,Ehrhardt J,Witte OW,Mayer G,Rupprecht S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite numerous studies, the role of patent foramen ovale (PFO) as a risk factor for stroke due to paradoxical embolism is still controversial. On the assumption that specific lesion patterns, in particular multiple acute ischaemic lesions on diffusion-weighted magnetic resonance imaging, indica...

journal_title：European journal of neurology

authors： Feurer R,Sadikovic S,Esposito L,Schwarze J,Bockelbrink A,Hemmer B,Sander D,Poppert H

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiological classification of patients with transient ischaemic attack (TIA) is a difficult endeavor and the use of serum biomarkers could improve the diagnostic accuracy. The aim of this study was to correlate atrial fibrillation, the main cardioembolic etiology (CE), with different serum bi...

journal_title：European journal of neurology

authors： Purroy F,Suárez-Luis I,Mauri-Capdevila G,Cambray S,Farré J,Sanahuja J,Piñol-Ripoll G,Quílez A,González-Mingot C,Begué R,Gil MI,Fernández E,Benabdelhak I

更新日期：2014-04-01 00:00:00

abstract：:We evaluated the cerebral hemodynamic features of severe bilateral carotid stenosis by assessing and comparing cerebral vasomotor reactivity (VMR) in the middle cerebral (MCA) and vertebral arteries (VA) by transcranial Doppler and the Diamox (1 g acetazolamide i.v.) test. VMR was evaluated by recording the percentage...

journal_title：European journal of neurology

authors： Gur AY,Bornstein NM

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased arterial stiffness causes vessel damage in the end-organs. Therefore small vessels in the brain may be susceptible to increased arterial stiffness. Cerebral microbleeds (CMBs) are topographically or pathophysiologically categorized as deep or infratentorial type and strictly lobar type....

journal_title：European journal of neurology

authors： Song TJ,Kim J,Kim YD,Nam HS,Lee HS,Nam CM,Heo JH

更新日期：2014-03-01 00:00:00

abstract：:The natural history of thymoma remains unpredictable because of the possibility of recurrence not infrequent after resection, but generally confined to the mediastinum Rufini et al. (1997). ...

journal_title：European journal of neurology

authors： Moretti R,Nasuelli D,Torre P,Antonello RM,Cazzato G,Stanta G

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS)-related genes and mutations have been increasingly discovered recently and an improved understanding of genotype-phenotype relationships may help to predict the disease course and refine genetic diagnosis. METHODS:We collected clinical data and blood samples f...

journal_title：European journal of neurology

authors： Chen W,Xie Y,Zheng M,Lin J,Huang P,Pei Z,Yao X

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies investigating the association between 25-hydroxyvitamin D [25(OH)D] and cognition in the very old (85+) are lacking. METHODS:Cross-sectional (baseline) and prospective data (up to 3 years follow-up) from 775 participants in the Newcastle 85+ Study were analysed for global (measured by th...

journal_title：European journal of neurology

authors： Granic A,Hill TR,Kirkwood TB,Davies K,Collerton J,Martin-Ruiz C,von Zglinicki T,Saxby BK,Wesnes KA,Collerton D,Mathers JC,Jagger C

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Calculation of the cerebrospinal fluid:serum glucose (CSF:SGlu ) ratio is part of the routine cerebrospinal fluid (CSF) work-up. Reference values have been defined for lumbar CSF, but are lacking for ventricular CSF. The objective of this study was to investigate whether the CSF:SGlu ratio is sim...

journal_title：European journal of neurology

authors： Hegen H,Walde J,Auer M,Deisenhammer F

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Myasthenia gravis (MG) is an autoimmune disease caused by antibody mediated impairment in the neuromuscular junction. Seronegative MG (SNMG) without antibodies against acetylcholine receptor (AChR) and muscle-specific kinase (MuSK) by routine assays accounts for about 20% of all MG patients. MET...

journal_title：European journal of neurology

authors： Hong Y,Zisimopoulou P,Trakas N,Karagiorgou K,Stergiou C,Skeie GO,Hao HJ,Gao X,Owe JF,Zhang X,Yue YX,Romi F,Wang Q,Li HF,Gilhus NE,Tzartos SJ

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is limited data of neurovascular coupling on stroke patients, especially on comparison of different etiologies. We aim to test the hypothesis that patients with small vessel disease (SVD) are impaired on neurovascular coupling rather than stroke patient with large intracranial artery stenos...

journal_title：European journal of neurology

authors： Lin WH,Hao Q,Rosengarten B,Leung WH,Wong KS

更新日期：2011-05-01 00:00:00

abstract：:We examined clinical presentations, neuropsychological findings, and perfusion patterns of (99m)Tc-ethyl cysteinate dimer (ECD) single photon emission computed tomography (SPECT) in patients with early stage dementia with Lewy bodies (DLB) (n = 17) and Parkinson's disease (PD) (n = 16), with age-matched healthy contro...

journal_title：European journal of neurology

authors： Chang CC,Liu JS,Chang YY,Chang WN,Chen SS,Lee CH

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this prospective study was to show and compare the rate of large-fiber involvement with near-nerve needle sensory (NNNS) nerve conduction study (NCS) and with medial plantar NCS recorded with surface electrodes in a group of patients who had clinically pure small-fiber sensory neuropat...

journal_title：European journal of neurology

authors： Uluc K,Temucin CM,Ozdamar SE,Demirci M,Tan E

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Better understanding the incidence, predictors and mechanisms of early neurological deterioration (END) following intravenous thrombolysis (IVT) for acute stroke with mild symptoms and isolated internal carotid artery occlusion (iICAo) may inform therapeutic decisions. METHODS:From a multicenter...

journal_title：European journal of neurology

authors： Boulenoir N,Turc G,Henon H,Laksiri N,Mounier-Véhier F,Girard Buttaz I,Duong DL,Papassin J,Yger M,Triquenot A,Lyoubi A,Ter Schiphorst A,Denier C,Baron JC,Seners P,MINOR-STROKE Collaborators.

更新日期：2021-02-01 00:00:00

abstract：:The authors performed neurological, visual evoked potentials (VEP) and electroneurography (ENG) examinations on three groups of workers with occupational exposure to mercury vapors (Hg(0)), and on a control group. The exposure of dental professionals (n = 36) was mild, that of chloralkali plant workers (n = 36) was in...

journal_title：European journal of neurology

authors： Urban P,Lukás E,Nerudová J,Cábelková Z,Cikrt M

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Botulinum toxin type A (BoNT/A) is a highly effective and well-tolerated treatment for focal dystonias. The BoNT/A in Botox and Dysport is part of a high-molecular-weight complex that contains hemagglutinins and other non-toxic proteins, whilst Xeomin is a highly purified BoNT/A free of such comp...

journal_title：European journal of neurology

authors： Benecke R

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To examine the frequencies and clinical characteristics of fallers and non-fallers at different stages of Parkinson's disease (PD). METHODS:The sample consisted of 232 patients in an unselected cross-sectional cohort of patients with PD, 207 newly diagnosed and drug naive patients and 175 contro...

journal_title：European journal of neurology

authors： Hiorth YH,Lode K,Larsen JP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that repetitive transcranial magnetic stimulation (rTMS) can reduce chronic tinnitus. However, treatment results are characterized by high interindividual variability. Therefore, the identification of predictors for treatment response is of high clinical relevance. METHODS:Clini...

journal_title：European journal of neurology

authors： Frank G,Kleinjung T,Landgrebe M,Vielsmeier V,Steffenhagen C,Burger J,Frank E,Vollberg G,Hajak G,Langguth B

更新日期：2010-07-01 00:00:00

abstract：:Visual system dysfunction has been reported in Parkinson's disease (PD). The objective of the present study was to evaluate a putative association of distorted colour vision and delayed initiation and execution of movement in PD. We performed the Farnsworth-Munsell 100-hue test and estimated the total error score in 3...

journal_title：European journal of neurology

authors： Müller T,Kuhn W,Büttner T,Przuntek H

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Data on the role of endogenous sex steroids in cerebrovascular disease are sparse. Estradiol is a hormone with diverse actions on the central nervous system. Our aim was to investigate the role of circulating estradiol levels in a postmenopausal acute stroke population. METHODS:During a time-period of 2 yea...

journal_title：European journal of neurology

authors： Pappa T,Vemmos K,Mantzou E,Savvari P,Stamatelopoulos K,Alevizaki M

更新日期：2012-10-01 00:00:00

abstract：:Jaw-opening dystonia (oromandibular dystonia with jaw-opening; Brueghel's syndrome) is a rare condition, and only a limited number of cases have been reported in the literature. However, many patients may remain undiscovered or misdiagnosed, like a patient described previously. A case (40-year-old man) of jaw-opening ...

journal_title：European journal of neurology

authors： Miyaoka T,Miura S,Seno H,Inagaki T,Horiguchi J

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High levels of glutamic acid decarboxylase (GAD)-ab were initially described in patients with stiff person syndrome, and have since also been observed in patients with other neurological diseases. Temporal lobe epilepsy (TLE) seems to be specially associated. Our purpose is to describe the preval...

journal_title：European journal of neurology

authors： Falip M,Carreño M,Miró J,Saiz A,Villanueva V,Quílez A,Molins A,Barceló I,Sierra A,Graus F

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Predicting the course of behavioural variant frontotemporal dementia (bvFTD) remains a major clinical challenge. This study aimed to identify factors that predict survival and clinical progression in bvFTD. METHODS:Consecutive patients with clinically probable bvFTD were prospectively followed u...

journal_title：European journal of neurology

authors： Agarwal S,Ahmed RM,D'Mello M,Foxe D,Kaizik C,Kiernan MC,Halliday GM,Piguet O,Hodges JR

更新日期：2019-05-01 00:00:00

abstract：:We report on a patient who presented with isolated transient headache as the only manifestation of pituitary apoplexy. A high index of suspicion and MRI led to the diagnosis. Copyright 1998 Lippincott Williams & Wilkins ...

journal_title：European journal of neurology

authors： Hernandez A,Angeles Del Real M,Aguirre M,Vaamonde J,Gudin M,Ibanez R

更新日期：1998-09-01 00:00:00

abstract：:We present the baseline characteristics of 101 patients with normal pressure hydrocephalus (NPH), entering a study that evaluates the diagnostic reliability of CSF outflow resistance. Patients were assessed by a gait scale consisting of 10 features of walking and the number of steps and seconds necessary for 10 m, a d...

journal_title：European journal of neurology

authors： Boon AJ,Tans JT,Delwel EJ,Egeler-Peerdeman SM,Hanlo PW,Wurzer JA,Hermans J

更新日期：1997-01-01 00:00:00