Left temporal low-frequency rTMS for the treatment of tinnitus: clinical predictors of treatment outcome--a retrospective study.

Abstract:

BACKGROUND:There is increasing evidence that repetitive transcranial magnetic stimulation (rTMS) can reduce chronic tinnitus. However, treatment results are characterized by high interindividual variability. Therefore, the identification of predictors for treatment response is of high clinical relevance. METHODS:Clinical data of 194 patients with tinnitus were evaluated. All patients were treated with a standardized rTMS procedure (1 Hz, 10 days, 2000 stimuli/day, over the left temporal cortex). A potential influence on the outcome was analysed for the following parameters: age, gender, depression scores in Beck Depression Inventory (BDI) and tinnitus severity (TQ) before rTMS, lateralization, frequency and duration of tinnitus and extent of hearing loss. RESULTS:An effect of tinnitus laterality was observed. In patients with left-sided or bilateral tinnitus, rTMS resulted in a statistically significant reduction of TQ scores, whereas patients with right-sided tinnitus did not show a significant improvement after rTMS treatment. However, in correlation analyses, we found a trend which did not reach statistical significance that in the subgroup of treatment responders tinnitus duration influenced rTMS outcome. In addition, a multiple regression analysis identified the TQ score at baseline as a significant predictor for treatment outcome. For all other investigated parameters, no statistically significant effects were found. CONCLUSIONS:This study suggests that left temporal low-frequency rTMS has beneficial effects in left-sided and bilateral tinnitus, but not in right-sided tinnitus. In line with the results from earlier studies involving smaller samples, tinnitus duration was found to influence rTMS outcome.

journal_name

Eur J Neurol

authors

Frank G,Kleinjung T,Landgrebe M,Vielsmeier V,Steffenhagen C,Burger J,Frank E,Vollberg G,Hajak G,Langguth B

doi

10.1111/j.1468-1331.2010.02956.x

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

951-6

issue

7

eissn

1351-5101

issn

1468-1331

pii

ENE2956

journal_volume

17

pub_type

杂志文章
  • Current evidence for the use of botulinum toxin type A in the management of children with cerebral palsy: a systematic review.

    abstract::Management of children with cerebral palsy (CP) is the focus of considerable resources in many countries, so that evaluation of the efficacy for new and established treatments is imperative. Botulinum toxin type A (BTX-A) is a relatively new method of spasticity management in children with cerebral palsy. It has been ...

    journal_title:European journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1468-1331.2001.00034.x

    authors: Boyd RN,Hays RM

    更新日期:2001-11-01 00:00:00

  • Minocycline and matrix metalloproteinase inhibition in acute intracerebral hemorrhage: a pilot study.

    abstract:BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) is a devastating cerebrovascular disorder with high morbidity and mortality. Minocycline is a matrix metalloproteinase-9 (MMP-9) inhibitor that may attenuate secondary mechanisms of injury in ICH. The feasibility and safety of minocycline in ICH patients were evalua...

    journal_title:European journal of neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ene.13403

    authors: Chang JJ,Kim-Tenser M,Emanuel BA,Jones GM,Chapple K,Alikhani A,Sanossian N,Mack WJ,Tsivgoulis G,Alexandrov AV,Pourmotabbed T

    更新日期:2017-11-01 00:00:00

  • Intrafusal effects of botulinum toxin in post-stroke upper limb spasticity.

    abstract::A previous study in subjects with focal dystonia suggested that the greater and longer-lasting effect induced by botulinum toxin type A (BoNT-A) on the tonic vibration reflex (TVR) than on the maximal M-wave (M-max) might be the physiological marker of the toxin's action at the level of intrafusal muscle fibres. With ...

    journal_title:European journal of neurology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1468-1331.2008.02076.x

    authors: Trompetto C,Bove M,Avanzino L,Francavilla G,Berardelli A,Abbruzzese G

    更新日期:2008-04-01 00:00:00

  • Vitamin D, HLA-DRB1 and Epstein-Barr virus antibody levels in a prospective cohort of multiple sclerosis patients.

    abstract:BACKGROUND AND PURPOSE:Our objective was to study the association between serum levels of anti Epstein-Barr virus nuclear antigen 1 (EBNA-1) antibody and 25-hydroxyvitamin D (25(OH)D) in a prospective cohort of patients with relapsing-remitting multiple sclerosis. METHOD:The study comprised 90 patients with relapsing-...

    journal_title:European journal of neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ene.12986

    authors: Wergeland S,Myhr KM,Løken-Amsrud KI,Beiske AG,Bjerve KS,Hovdal H,Midgard R,Kvistad SS,Holmøy T,Riise T,Torkildsen Ø

    更新日期:2016-06-01 00:00:00

  • Primary progressive multiple sclerosis: clinical and paraclinical characteristics with application of the new diagnostic criteria.

    abstract::The aim of our study was to analyse clinical and paraclinical characteristics of patients with multiple sclerosis (MS) with previous diagnosis of primary-progressive (PP) MS according to the Poser's criteria and further investigate if they fulfil the McDonald's diagnostic criteria for this disorder. A total of 561 MS ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2004.00797.x

    authors: Dujmović I,Mesaros S,Pekmezović T,Lević Z,Drulović J

    更新日期:2004-07-01 00:00:00

  • Parkinsonism and tardive antecollis in frontotemporal dementia--increased sensitivity to newer antipsychotics?

    abstract::Frontotemporal dementia (FTD) often presents with behavioural changes warranting treatment with antipsychotic medications. It is known that patients with Lewy body dementia are sensitive to developing extrapyramidal symptoms (EPS) from these medications. This has not been emphasized in FTD. We report three patients wi...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2007.02032.x

    authors: Czarnecki K,Kumar N,Josephs KA

    更新日期:2008-02-01 00:00:00

  • Inflammation, edema and poor outcome are associated with hyperthermia in hypertensive intracerebral hemorrhages.

    abstract:BACKGROUND AND PURPOSE:The deleterious effect of hyperthermia on intracerebral hemorrhage (ICH) has been studied. However, the results are not conclusive and new studies are needed to elucidate clinical factors that influence the poor outcome. The aim of this study was to identify the clinical factors (including ICH et...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13677

    authors: Iglesias-Rey R,Rodríguez-Yáñez M,Arias S,Santamaría M,Rodríguez-Castro E,López-Dequidt I,Hervella P,Sobrino T,Campos F,Castillo J

    更新日期:2018-09-01 00:00:00

  • Neurophysiological study of critical illness polyneuropathy and myopathy in mechanically ventilated children; additional aspects in paediatric critical illness comorbidities.

    abstract:BACKGROUND AND PURPOSE:Critical illness polyneuropathy and myopathy (CIP/CIM) is being increasingly recognized as a significant clinical problem in critically ill children especially if they have spent long periods in the intensive care unit. So the aim was to determine the frequency of CIP/CIM amongst mechanically ven...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13649

    authors: Thabet Mahmoud A,Tawfik MAM,Abd El Naby SA,Abo El Fotoh WMM,Saleh NY,Abd El Hady NMS

    更新日期:2018-07-01 00:00:00

  • Headache in primary Sjøgren's syndrome: a population-based retrospective cohort study.

    abstract:BACKGROUND:We investigated whether the prevalence of primary headaches was higher in patients with primary Sjøgren's syndrome (PSS) than in healthy individuals. METHODS:This retrospective cohort study included 71 patients with PSS (patients) based on the American European Consensus Classification criteria, and 71 age-...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.12033

    authors: Tjensvoll AB,Harboe E,Gøransson LG,Beyer MK,Greve OJ,Kvaløy JT,Omdal R

    更新日期:2013-03-01 00:00:00

  • Calculi and memory.

    abstract::We describe a case of transient global amnesia related to symptomatic renal stones. Transient global amnesia has been related to intense emotional or painful experiences, such as sexual intercourse, cold water bathing and trigeminal stimulation. Renal stones may be at the origin of a painful experience and thus may in...

    journal_title:European journal of neurology

    pub_type: 信件

    doi:10.1046/j.1468-1331.2001.00205.x

    authors: Kettaneh A,Gobron C,Fain O,Mohib S,Thomas M

    更新日期:2001-03-01 00:00:00

  • Clinical and laboratory-reconfirmed myasthenia gravis: a population-based study.

    abstract::The aim of this study was to compare the clinically based prevalence of myasthenia gravis (MG) with the prevalence of laboratory-confirmed cases. All patients with a diagnosis of MG living in Estonia as on 1 January 1997 were asked to participate in re-examination. The criteria for laboratory-supported MG were weaknes...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2007.02038.x

    authors: Oöpik M,Puksa L,Lüüs SM,Kaasik AE,Jakobsen J

    更新日期:2008-03-01 00:00:00

  • Treatment of miscellaneous idiopathic headache disorders (Group 4 of the IHS classification)--report of an EFNS task force.

    abstract:BACKGROUND AND PURPOSE:Certain miscellaneous idiopathic headache disorders, which are regarded as entities, are grouped in Chapter 4 of the International Classification of Headache Disorders. Recent epidemiological research suggests that these headache disorders are underdiagnosed. OBJECTIVES:To give expert recommenda...

    journal_title:European journal of neurology

    pub_type: 杂志文章,实务指引

    doi:10.1111/j.1468-1331.2011.03389.x

    authors: Evers S,Goadsby P,Jensen R,May A,Pascual J,Sixt G,EFNS task force.

    更新日期:2011-06-01 00:00:00

  • A critical appraisal of randomized controlled trials on intravenous phenytoin in convulsive status epilepticus.

    abstract::Since the 1970s, intravenous (IV) phenytoin (PHT) has traditionally been used as second-stage treatment for convulsive status epilepticus (SE) after failure of benzodiazepines. The aim of this review was to critically assess the evidence supporting the use of IV PHT as treatment of convulsive SE in patients of any age...

    journal_title:European journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1111/ene.13560

    authors: Brigo F,Bragazzi NL,Lattanzi S,Nardone R,Trinka E

    更新日期:2018-03-01 00:00:00

  • No difference in efficacy of two different doses of intravenous immunoglobulins in MS: clinical and MRI assessment.

    abstract::We performed a double-blind, placebo-controlled study to evaluate the efficacy of low and high dose of intravenous immunoglobulins (IVIG) in relapsing/remitting (RR) multiple sclerosis (MS). Patients (n = 49) with clinical definite RR MS were randomly allocated to three groups and treated with 0.2 g/kg (n = 17) or 0.4...

    journal_title:European journal of neurology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1468-1331.2002.00500.x

    authors: Lewańska M,Siger-Zajdel M,Selmaj K

    更新日期:2002-11-01 00:00:00

  • Association between remote diffusion-weighted imaging lesions and cerebral small vessel disease in primary intracerebral hemorrhage.

    abstract:BACKGROUND AND PURPOSE:The aim of this study was to examine the association amongst remote diffusion-weighted imaging lesions (R-DWILs), imaging markers of cerebral small vessel disease (cSVD) and total cSVD burden in patients with primary intracerebral haemorrhage (ICH). METHODS:In total, 344 consecutive primary ICH ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13915

    authors: Xu XH,Ye XH,Li JW,Cai JS,Gao T,Zhang WJ,Zhao GH,Tong LS,Gao F

    更新日期:2019-07-01 00:00:00

  • Evolution of striatal degeneration in McLeod syndrome.

    abstract:BACKGROUND AND PURPOSE:McLeod neuroacanthocytosis syndrome (MLS) is an X-linked multisystem disorder with CNS manifestations resembling Huntington disease. Neuroimaging studies revealed striatal atrophy with predominance of the caudate nucleus. Our previous cross-sectional MRI study showed an association of volume loss...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2009.02872.x

    authors: Valko PO,Hänggi J,Meyer M,Jung HH

    更新日期:2010-04-01 00:00:00

  • Constitutional risk factors for focal neuropathies in patients referred for electromyography.

    abstract:BACKGROUND AND PURPOSE:It is well established that patient-related constitutional features predispose to focal peripheral neuropathies. Some of these risk factors were investigated in common focal neuropathies encountered in patients referred for electromyography. METHODS:Gender, age, height and body mass index (BMI) ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14118

    authors: Martínez-Aparicio C,Jääskeläinen SK,Puksa L,Reche-Lorite F,Torné-Poyatos P,Paniagua Soto J,Falck B

    更新日期:2020-03-01 00:00:00

  • Homocysteine and holo-transcobalamin and the risk of dementia and Alzheimers disease: a prospective study.

    abstract:BACKGROUND:Elevated total homocysteine (tHcy) levels may be caused by vitamin B12 deficiency and are linked to Alzheimers disease (AD) in some studies, although the evidence is mixed. Another marker of vitamin B12 deficiency, holo-transcobalamin (holo-TC), has not been studied in a prospective setting. OBJECTIVE:To in...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2009.02590.x

    authors: Kivipelto M,Annerbo S,Hultdin J,Bäckman L,Viitanen M,Fratiglioni L,Lökk J

    更新日期:2009-07-01 00:00:00

  • Improvement of medical judgments by numerical training in patients with multiple sclerosis.

    abstract:BACKGROUND AND PURPOSE:People with multiple sclerosis (MS) have to face important decisions with regard to their medical treatment. The aim of this study was to evaluate whether a targeted cognitive training reduces framing effects and thus improves medical judgments. METHODS:This was a randomized, double-blind, cross...

    journal_title:European journal of neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ene.13778

    authors: Zamarian L,Delazer M,Ehling R,Pertl MT,Bsteh G,Wenter J,Glatzl S,Brenneis C,Benke T,Berger T

    更新日期:2019-01-01 00:00:00

  • Dimethyl fumarate-induced lymphocyte count drop is related to clinical effectiveness in relapsing-remitting multiple sclerosis.

    abstract:BACKGROUND AND PURPOSE:Dimethyl fumarate (DMF) causes a mean lymphocyte count drop of approximately 30% in relapsing-remitting multiple sclerosis (RRMS) patients. The relationship between this reduction and DMF effectiveness is controversial. The objective was to investigate if the decrease in absolute lymphocyte count...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14538

    authors: Tsantes E,Curti E,Ferraro D,Lugaresi A,Baldi E,Montepietra S,Immovilli P,Simone AM,Mancinelli L,Strumia S,Vitetta F,Foschi M,Ferri C,Ferrarini C,Sola P,Granella F

    更新日期:2021-01-01 00:00:00

  • Neurology and psychiatry: waking up to opportunities of sleep. : State of the art and clinical/research priorities for the next decade.

    abstract::In recent years, evidence has emerged for a bidirectional relationship between sleep and neurological and psychiatric disorders. First, sleep-wake disorders (SWDs) are very common and may be the first/main manifestation of underlying neurological and psychiatric disorders. Secondly, SWDs may represent an independent r...

    journal_title:European journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1111/ene.12781

    authors: Bassetti CL,Ferini-Strambi L,Brown S,Adamantidis A,Benedetti F,Bruni O,Cajochen C,Dolenc-Groselj L,Ferri R,Gais S,Huber R,Khatami R,Lammers GJ,Luppi PH,Manconi M,Nissen C,Nobili L,Peigneux P,Pollmächer T,Randerath W

    更新日期:2015-10-01 00:00:00

  • Perimysial microarteriopathy in dermatomyositis with anti-nuclear matrix protein-2 antibodies.

    abstract:BACKGROUND AND PURPOSE:Dermatomyositis (DM) with anti-nuclear matrix protein-2 (NXP-2) antibodies usually shows multifocal ischaemic lesions in muscle. Here, we aimed to investigate the microarteriopathy underlying muscle ischaemia in anti-NXP-2-positive DM. METHODS:A total of 16 patients diagnosed with anti-NXP-2-pos...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14097

    authors: Liu Y,Zheng Y,Gang Q,Xie Z,Jin Y,Zhang X,Deng X,Hao H,Gao F,Zhang Z,Xiong H,Zhang W,Wang Z,Yuan Y

    更新日期:2020-03-01 00:00:00

  • The segmental diffusivity profile of amyotrophic lateral sclerosis associated white matter degeneration.

    abstract:BACKGROUND AND PURPOSE:Magnetic resonance diffusivity indices have been repeatedly proposed as biomarkers of neurodegeneration in amyotrophic lateral sclerosis (ALS), but no consensus exists as to which diffusivity parameter is the most sensitive to identify early degenerative changes. Despite numerous studies, surpris...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13038

    authors: Schuster C,Elamin M,Hardiman O,Bede P

    更新日期:2016-08-01 00:00:00

  • Growth hormone/IGF-1 axis longitudinal evaluation in clinically isolated syndrome patients on interferon β-1b therapy: stimulation tests and correlations with clinical and radiological conversion to multiple sclerosis.

    abstract:BACKGROUND AND PURPOSE:Growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis abnormalities in multiple sclerosis (MS) suggest their role in its pathogenesis. Interferon β (IFN-β) efficacy could be mediated also by an increase of IGF-1 levels. A 2-year longitudinal study was performed to estimate the prevalence ...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13207

    authors: Lanzillo R,Di Somma C,Quarantelli M,Carotenuto A,Pivonello C,Moccia M,Cianflone A,Marsili A,Puorro G,Saccà F,Russo CV,De Luca Picione C,Ausiello F,Colao A,Brescia Morra V

    更新日期:2017-02-01 00:00:00

  • Prescribing patterns of antiepileptic drugs in Italy: a nationwide population-based study in the years 2000-2005.

    abstract::To evaluate prevalence of use and prescribing patterns of antiepileptic drugs (AEDs) in Italian general practice. Primary care data were obtained from the Health Search Database, a longitudinal observational database implemented by the Italian College of General Practitioners (GPs). We selected 465 061 subjects regist...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2007.01970.x

    authors: Savica R,Beghi E,Mazzaglia G,Innocenti F,Brignoli O,Cricelli C,Caputi AP,Musolino R,Spina E,Trifirò G

    更新日期:2007-12-01 00:00:00

  • Adult-onset very-long-chain acyl-CoA dehydrogenase deficiency (VLCADD).

    abstract:BACKGROUND AND PURPOSE:Very-long-chain acyl-CoA dehydrogenase deficiency (VLCADD) is a hereditary disorder of mitochondrial long-chain fatty acid oxidation that has variable presentations, including exercise intolerance, cardiomyopathy and liver disease. The aim of this study was to describe the clinical and genetic ma...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.14402

    authors: Fatehi F,Okhovat AA,Nilipour Y,Mroczek M,Straub V,Töpf A,Palibrk A,Peric S,Rakocevic Stojanovic V,Najmabadi H,Nafissi S

    更新日期:2020-11-01 00:00:00

  • Chronic obstructive pulmonary disease as a risk factor for stroke-related seizures.

    abstract::Chronic obstructive pulmonary disease (COPD) is a risk factor for cardiovascular disorders and different types of stroke. The present retrospective study investigates whether COPD is also a risk factor for the development of seizures in stroke patients. The study population consisted of 237 patients with stroke-relate...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2007.01829.x

    authors: De Reuck J,Proot P,Van Maele G

    更新日期:2007-09-01 00:00:00

  • A 2-year follow-up study of cigarette smoking and risk of dementia.

    abstract::The report focused on investigating the relationship between cigarette smoking and dementia in elderly people through prospective studies. We did a 2-year follow-up study of elderly people. A total of 2820 participants aged 60 years old and over from six communities of Chongqing agreed to take part. Dementia was diagn...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1046/j.1468-1331.2003.00779.x

    authors: Juan D,Zhou DH,Li J,Wang JY,Gao C,Chen M

    更新日期:2004-04-01 00:00:00

  • Increased levels of inflammatory chemokines in amyotrophic lateral sclerosis.

    abstract:BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS) is classically assumed to be a neurodegenerative disorder. Inflammation has been observed in CNS tissue in ALS patients. We investigated the expression and prognostic relevance of proinflammatory chemokines in ALS. METHODS:We analyzed nine chemokines, eotaxin,...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/j.1468-1331.2009.02560.x

    authors: Kuhle J,Lindberg RL,Regeniter A,Mehling M,Steck AJ,Kappos L,Czaplinski A

    更新日期:2009-06-01 00:00:00

  • Cerebrospinal fluid:serum glucose ratio in the ventricular and lumbar compartments: implications for clinical practice.

    abstract:BACKGROUND AND PURPOSE:Calculation of the cerebrospinal fluid:serum glucose (CSF:SGlu ) ratio is part of the routine cerebrospinal fluid (CSF) work-up. Reference values have been defined for lumbar CSF, but are lacking for ventricular CSF. The objective of this study was to investigate whether the CSF:SGlu ratio is sim...

    journal_title:European journal of neurology

    pub_type: 杂志文章

    doi:10.1111/ene.13513

    authors: Hegen H,Walde J,Auer M,Deisenhammer F

    更新日期:2018-02-01 00:00:00