Abstract:
:Apoptosis, a genetically regulated form of cell death with distinct biochemical and morphological features, plays a relevant physiological and pathological role in the organism, being pivotal in the maintenance of tissue development and homeostasis in the adult as well as in the regulation of immune responses. Deregulation of this process causes several human disorders including cancer, autoimmune and neurodegenerative diseases. Thus, modulation of the apoptotic process and of cell death in general, is a potential therapeutic approach for the treatment of several human pathologies.
journal_name
Biochem Biophys Res Communjournal_title
Biochemical and biophysical research communicationsauthors
Agostini M,Tucci P,Melino Gdoi
10.1016/j.bbrc.2011.09.081subject
Has Abstractpub_date
2011-10-28 00:00:00pages
451-5issue
3eissn
0006-291Xissn
1090-2104pii
S0006-291X(11)01685-8journal_volume
414pub_type
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