Variation in complement component C1 inhibitor in age-related macular degeneration.

abstract：:We investigated the effects of ML I and its isolated chains, A and B, in regard to selected functions of phagocytes (human granulocytes, paraffin-oil stimulated M phi from guinea pigs). On these cells, ML I has no cytotoxic effect between 10(-14) and 10(-8) (trypan blue exclusion and ethidium bromide exclusion). Over ...

journal_title：Immunobiology

authors： Metzner G,Franz H,Kindt A,Fahlbusch B,Süss J

更新日期：1985-07-01 00:00:00

abstract：:The major target organ of systemic infection with the intracellular bacterium Listeria monocytogenes is the liver, to where inflammatory leukocytes are rapidly recruited. We determined by reverse transcriptase polymerase chain reaction the early chemokine response in the liver after systemic infection of mice with lis...

journal_title：Immunobiology

authors： Barsig J,Flesch IE,Kaufmann SH

更新日期：1998-07-01 00:00:00

abstract：:Asthma is characterized by inflammation, pulmonary remodeling and bronchial hyperresponsiveness. We have previously shown that treatment with angiotensin-(1-7) [Ang-(1-7)] promotes resolution of eosinophilic inflammation and prevents chronic allergic lung inflammation. Here, we evaluated the effect of treatment with t...

journal_title：Immunobiology

authors： Magalhães GS,Gregório JF,Ramos KE,Cançado-Ribeiro ATP,Baroni IF,Barcelos LS,Pinho V,Teixeira MM,Santos RAS,Rodrigues-Machado MG,Campagnole-Santos MJ

更新日期：2020-05-01 00:00:00

abstract：:Based on the similar effects that HIV-1 gp41 like human type I interferons (IFN-alpha and -beta) upregulated MHC expression and inhibited lymphocyte proliferation, we compared amino acid sequences of gp41 and human type I interferons (IFN-alpha and -beta), and found sequence-similarity existing between the immunosuppr...

journal_title：Immunobiology

authors： Chen YH,Dierich MP

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Following any acute irritation lung function declines rapidly. Reasons for pulmonary deterioration in humans had been attributed to the action of either interleukin-6 or interleukin-8 in the lungs. OBJECTIVES:The present study investigates the association between immune response and decline in lung function...

journal_title：Immunobiology

authors： Wölbeling F,Munder A,Kerber-Momot T,Neumann D,Hennig C,Hansen G,Tümmler B,Baumann U

更新日期：2011-08-01 00:00:00

abstract：:Three different anti-CD26 monoclonal antibodies (mAbs) are described, which specifically inhibited proliferation of human T lymphocytes after stimulation with PHA, tetanus toxoid or soluble anti-CD3 mAb. Anti-CD26 mAbs induced in T cells a dose-dependent shift of the maximum of DNA synthesis, which was due to a transi...

journal_title：Immunobiology

authors： Mattern T,Ansorge S,Flad HD,Ulmer AJ

更新日期：1993-06-01 00:00:00

abstract：:Mugwort pollen allergy is frequent in parts of Europe. As mugwort pollen contains only one major allergen, Art v 1, which harbors only one T cell epitope, we employed mugwort pollen allergy as a model to study allergen-specific T cell responses. However, after 2004, we noticed a drastic decrease in the T cell response...

journal_title：Immunobiology

authors： Van Hemelen D,Hemmer W,Kmenta M,Berger UB,Kinaciyan T,Bohle B,Jahn-Schmid B

更新日期：2019-09-01 00:00:00

abstract：:The homotypic cell aggregation of leukocytes is an unique adhesive event which is caused by cellular activation. Anti-CD44 monoclonal antibody (mAb) induces homotypic cell aggregation of hematopoietic cell lines expressing CD44, but the mechanism of homotypic cell aggregation is poorly understood. We used four mAbs ag...

journal_title：Immunobiology

authors： Cao L,Yoshino T,Nishiuchi R,Yamadori I,Akagi T

更新日期：1995-06-01 00:00:00

abstract：:Toll-like receptors (TLR) initiate innate and often affect adaptive immune response. This study aimed to determine if TLR response and T regulatory cell (Treg) function in peripheral blood mononuclear cells (PBMC) correlate with clinical severity in non-infectious asthma. TLR1-9 expression and representative response ...

journal_title：Immunobiology

authors： Lee WI,Yao TC,Yeh KW,Chen LC,Ou LS,Huang JL,PATCH Study Group.

更新日期：2013-02-01 00:00:00

abstract：:Phagocytosis Inhibitory Factor (PIF), a small (< 3000 D) molecule, was partially purified from human red blood cell membranes. This factor inhibits latex phagocytosis by monocytic cells. PIF is not toxic under the experimental conditions employed and the phagocytosis inhibitory activity is reversible since removal of ...

journal_title：Immunobiology

authors： Baranyi L,Baranji K,Yoshida T,Okada N,Okada H

更新日期：1994-12-01 00:00:00

abstract：:Pythiosis is a life-threatening disease caused by the fungus-like microorganism Pythium insidiosum that can lead to death if not treated. Since P. insidiosum has particular cell wall characteristics, pythiosis is difficult to treat, as it does not respond well to traditional antifungal drugs. In our study, we investig...

journal_title：Immunobiology

authors： Ledur PC,Tondolo JSM,Jesus FPK,Verdi CM,Loreto ÉS,Alves SH,Santurio JM

更新日期：2018-03-01 00:00:00

abstract：:Respiratory viral infections have been implicated in the origin of, protection from and exacerbation of allergy-related symptoms in a variety of ways. Viral infections are closely linked to infantile wheezing. Severe bronchiolitis in early infancy may predispose to chronic childhood asthma as well as allergic sensitiz...

journal_title：Immunobiology

authors： Xepapadaki P,Papadopoulos NG

更新日期：2007-01-01 00:00:00

abstract：:This study investigated the actin scavenger function of the vitamin D binding protein (DBP) in vivo using DBP null (-/-) mice. Intravenous injection of G-actin into wild-type (DBP+/+) and DBP-/- mice showed that contrary to expectations, DBP+/+ mice developed more severe acute lung inflammation. Inflammation was restr...

journal_title：Immunobiology

authors： Ge L,Trujillo G,Miller EJ,Kew RR

更新日期：2014-03-01 00:00:00

abstract：:High Mphi:T cell ratios suppress the immune response to the retroviral superantigen Mls by IFNgamma-triggered production of the arg- and trp-consuming enzymes iNOS and IDO. Attempts to reverse suppression by treatment with pro-inflammatory cytokines revealed that IL-6 improved the T cell response to Mls and the pro-he...

journal_title：Immunobiology

authors： Silberman D,Bucknum A,Kozlowski M,Matlack R,Riggs J

更新日期：2010-01-01 00:00:00

abstract：:A cyclophosphamide (CP)-induced tolerance system in mice that primarily consists of donor cell injection followed by CP-treatment was found useful for inducing a long-lasting allo- or xeno-tolerance to various solid organs. In the cells-followed-by-CP system, the sequential mechanisms of tolerance were clarified using...

journal_title：Immunobiology

authors： Mayumi H,Umesue M,Nomoto K

更新日期：1996-07-01 00:00:00

abstract：:Dogs with lymphoma are established as good model for human non-Hodgkin lymphoma studies. Canine cell lines derived from lymphomas may be valuable tools for testing new therapeutic drugs. In this context, we established a canine T-cell line, PER-VAS, from a primary aggressive T-cell lymphoma with large granular morphol...

journal_title：Immunobiology

authors： Bonnefont-Rebeix C,Fournel-Fleury C,Ponce F,Belluco S,Watrelot D,Bouteille SE,Rapiteau S,Razanajaona-Doll D,Pin JJ,Leroux C,Marchal T

更新日期：2016-01-01 00:00:00

abstract：:Interleukin-6 (IL-6) induced increased, leukocyte and platelet counts on around day 20 when it was administered into [BALB/c-->C3H/He] bone marrow chimeras from day 1 to day 12. Increased leukocyte counts and hemoglobin (Hb) levels were also observed at around day 60 and from day 41 to 80, respectively. On the other h...

journal_title：Immunobiology

authors： Imamura M,Hashino S,Kobayashi H,Tanaka J,Imai K,Han M,Fujii Y,Kobayashi M,Higa T,Kasai M

更新日期：1994-06-01 00:00:00

abstract：:The phagocyte pattern recognition receptor Toll-like receptor 2 (TLR2) and the multi-receptor adaptor MyD88 contribute to the reduction of bacterial load in infections with intra- and extra-cellular Gram-positive bacteria. Their mechanism of antibacterial action is mostly unresolved but evident in vivo by an increased...

journal_title：Immunobiology

authors： Echchannaoui H,Bachmann P,Letiembre M,Espinosa M,Landmann R

更新日期：2005-01-01 00:00:00

abstract：:Although there have been numerous attempts to develop a successful vaccine against leishmaniasis, based on the clinical trial in this field, no vaccine against Leishmania in routine way can be found for globally effective vaccination in human. Amongst, first generation vaccines consisting of parasite fractions or whol...

journal_title：Immunobiology

authors： Jafari I,Heravi Shargh V,Shahryari M,Abbasi A,Jaafari MR,Khamesipour A,Badiee A

更新日期：2018-01-01 00:00:00

abstract：:Cartilage-hair hypoplasia (CHH), or McKusick type metaphyseal chondrodysplasia, was first recognized as a distinct entity in the Old Order Amish in the USA, but was later identified in other groups, and found to be unusually frequent among Finns. CHH is highly pleiotropic with manifestations that include short stature...

journal_title：Immunobiology

authors： Muñoz-Robles J,Allende LM,Clemente J,Calleja S,Varela P,Gonzalez L,de Pablos P,Paz E,Morales P

更新日期：2006-01-01 00:00:00

abstract：:In this study the SEB-activated LAK cytotoxicity was identified and characterized in human peripheral blood lymphocytes (PBMC). After 3 days of SEB stimulation, the PBMC acquired a cytotoxicity against traditional LAK targets, K-562 and Daudi, beside that human glomerular endothelial cells (HGEC) were effectively lyse...

journal_title：Immunobiology

authors： Seprényi G,Shibata T,Onody R,Kohsaka T

更新日期：1997-06-01 00:00:00

abstract：:A case of a 35-year-old female with multiple sclerosis is reported who developed without apparent prior sensitization a lymphocytotoxic antibody with anti-HLA-B8 specificity. The antibody persisted for several years with the same titer. The cytotoxic activity of the patient's serum was contained within the IgM fractio...

journal_title：Immunobiology

authors： Lenhard V,Diehm H,Römer W,Rauterberg EW,Kownatzki E,Roelcke D

更新日期：1982-02-01 00:00:00

abstract：:Macrophages located in airways and the alveolar space are continually exposed to different signals from the respiratory mucosa. In this respect, epithelial cells represent an important source of cytokines and mediators modulating the state of activation and/or differentiation of mononuclear phagocytes. Many of the pro...

journal_title：Immunobiology

authors： Striz I,Brabcova E,Kolesar L,Liu XD,Brabcova I,Sekerkova A,Poole JA,Jaresova M,Slavcev A,Rennard SI

更新日期：2011-10-01 00:00:00

abstract：:Culture supernatants (CS) from Hodgkin derived cell lines have previously been shown to contain colony stimulating activity (CSF) for human cord blood cells, fetal bone marrow and fetal liver cells. In this study 3-day CS from four Hodgkin lines (L428, L538, L540, L591) and two sublines (L428KS, L428KSA) were examined...

journal_title：Immunobiology

authors： Kortmann C,Burrichter H,Monner D,Jahn G,Diehl V,Peter HH

更新日期：1984-05-01 00:00:00

abstract：:Signal transduction by the Toll-like receptors (TLRs) is a key component of innate immunity against many pathogens and also underlies a large burden of human diseases. Therefore, the mechanisms and regulation of signaling from the TLRs are of considerable interest. Here we seek to determine the molecular mechanism by ...

journal_title：Immunobiology

authors： Zsengellér ZK,Gerard NP

更新日期：2020-03-01 00:00:00

abstract：:Cell walls from Streptococcus pyogenes strain Sv (Group A, M type 3) were lysed with M1 endo-N-acetylmuramidase, and the group A-specific carbohydrate antigen was purified by Sephadex G-100 gel filtration. The initial eluting antigen (M1gA) peak was assessed for mitogenic and polyclonal lymphocyte-activating propertie...

journal_title：Immunobiology

authors： Morisaki I,Kimura S,Torii M,Michalek SM,McGhee JR,Okahashi N,Hamada S

更新日期：1985-11-01 00:00:00

abstract：:Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium frequently isolated from lesions of patients with localized aggressive periodontitis. Lipopolysaccharide (LPS), a major cell wall component of Gram-negative bacteria, stimulates innate immune cells via Toll-like receptor 4 (TLR4) to initiate inflammato...

journal_title：Immunobiology

authors： Park OJ,Cho MK,Yun CH,Han SH

更新日期：2015-09-01 00:00:00

abstract：:IL-33 targeting ST2 receptor (T1/ST2), expressed on Th2 cell surface, regulates the production of cytokines like IL-17A and IL-31. We studied the role of IL-33/ST2 axis in IL-31 and IL-17A production in patients with allergic rhinitis (AR) and with concomitant allergic asthma and rhinitis (AAR). 20 healthy control sub...

journal_title：Immunobiology

authors： Vocca L,Di Sano C,Uasuf CG,Sala A,Riccobono L,Gangemi S,Albano GD,Bonanno A,Gagliardo R,Profita M

更新日期：2015-08-01 00:00:00

abstract：:Macrophage pre-treatment with bacterial lipopolysaccharide (LPS) boosts subsequent activation of the NLRP3 inflammasome, which controls caspase-1-dependent pro-inflammatory cytokine maturation. Previous work has attributed this phenomenon (known as LPS 'priming') to LPS-dependent induction of NLRP3 expression. Whilst ...

journal_title：Immunobiology

authors： Schroder K,Sagulenko V,Zamoshnikova A,Richards AA,Cridland JA,Irvine KM,Stacey KJ,Sweet MJ

更新日期：2012-12-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Immunobiology

authors： Luo HL,Wang DY,Wang HJ,Nie K,Huang WY

更新日期：2011-12-16 00:00:00