Phenylketonuria-related synaptic changes in a BTBR-Pah(enu2) mouse model.

abstract：:Since the first identification of an association between mutations in the connexin26 (Cx26) gene and autosomal recessive non-syndromic deafness it has been shown that several mutations in this gene cause recessive, sporadic, and dominant non-syndromic deafness. Three novel mutations in the Cx26 gene were identified in...

journal_title：Neuroreport

authors： Fuse Y,Doi K,Hasegawa T,Sugii A,Hibino H,Kubo T

更新日期：1999-06-23 00:00:00

abstract：:Bicuculline- and baclofen-insensitive GABA receptors (GABAC receptors) on bipolar cells acutely dissociated from carp retina were investigated with using the whole-cell patch-clamp recording technique. The currents of these cells mediated by GABAC receptors showed striking desensitization, even at low concentrations o...

journal_title：Neuroreport

authors： Han MH,Li Y,Yang XL

更新日期：1997-04-14 00:00:00

abstract：:In order to clarify whether neurophysiological profiles affect the performance of brain machine interfaces (BMI), we examined the relationships between amplitudes of movement-related cortical fields (MRCFs) and decoding performances during movement. Neuromagnetic activities were recorded in nine healthy participants d...

journal_title：Neuroreport

authors： Sugata H,Goto T,Hirata M,Yanagisawa T,Shayne M,Matsushita K,Yoshimine T,Yorifuji S

更新日期：2012-01-04 00:00:00

abstract：:Mammals react to acute hypoxia with an initial augmentation and a secondary depression of the respiratory rhythm generated by brain stem neuronal networks. To investigate the cytosolic level of energy rich phosphorus metabolites during these responses, we developed 31P nuclear magnetic resonance spectroscopy of the br...

journal_title：Neuroreport

authors： Piérard C,Champagnat J,Denavit-Saubie M,Gillet B,Beloeil JC,Guezennec CY,Barrère B,Pérès M

更新日期：1995-12-29 00:00:00

abstract：:The purpose of the present study was to determine the cortical areas contributing to the influence of the previous movement on the current movement. Right-handed healthy human participants abducted and then adducted the left index finger in response to a start cue. Twenty consecutive trials with 10 s intertrial interv...

journal_title：Neuroreport

authors： Oda H,Sawaguchi Y,Kunimura H,Kawasaki T,Hiraoka K

更新日期：2020-12-30 00:00:00

abstract：:Damage to central nervous system white matter is observed following hypoglycemia, raising the possibility that hypoglycemia influences oligodendrocytes and myelination. To examine effects of hypoglycemia on oligodendrocytes and myelin formation, we studied cultured oligodendrocyte precursor cells and cerebellar slice ...

journal_title：Neuroreport

authors： Yan H,Rivkees SA

更新日期：2006-01-23 00:00:00

abstract：:We investigated the effect of nitric oxide (NO) on N-methyl-D-aspartate (NMDA)-induced changes in levels of dopamine (DA) and its metabolite in the striatum using in vivo microdialysis. Local administration of 1mM NMDA into the striatum significantly augmented DA release in the striatum. Simultaneous administration of...

journal_title：Neuroreport

authors： Shibata M,Araki N,Ohta K,Hamada J,Shimazu K,Fukuuchi Y

更新日期：1996-01-31 00:00:00

abstract：:Neuroblastoma is an important problem in children. Long noncoding RNAs (lncRNAs) exhibit important roles in tumorigenicity of neuroblastoma. However, the role and mechanism of lncRNA small nucleolar RNA host gene 16 (SNHG16) in neuroblastoma tumorigenicity remain poorly understood. Forty-six neuroblastoma samples and ...

journal_title：Neuroreport

authors： Ge Y,Tan S,Bi J,Rao M,Yu Y,Tian L

更新日期：2020-12-09 00:00:00

abstract：:Retinal ganglion cells of the fish have the spontaneous capacity to regenerate after nerve crush, a phenomenon known to be facilitated by nerve growth factor (NGF). We have studied the high-affinity NGF receptor TrkA, during the regeneration of the tench (Tinca tinca L.) optic nerve, using immunocytochemical technique...

journal_title：Neuroreport

authors： Vecino E,Caminos E,Becker E,Rudkin BB,Evan GI,Martín-Zanca D

更新日期：1998-10-26 00:00:00

abstract：:Previous event-related potential studies in Indo-European languages reported a surprising finding that failed syntactic category processing appears to block lexical-semantic integration, suggesting a functional primacy of syntax over semantics. An event-related potential experiment was conducted to test whether there ...

journal_title：Neuroreport

authors： Yu J,Zhang Y

更新日期：2008-05-07 00:00:00

abstract：:High K+- or caffeine-induced Ca2+ signal was studied in freshly dissociated carp retinal ON-type bipolar cells using a confocal laser-scanning microscope. In response to 35 mM K+ exposure, a rise in [Ca2+]i appeared in both the terminal and soma, but was absent after removal of external Ca2+ or in the presence of 100 ...

journal_title：Neuroreport

authors： Wu D,Zhu PH

更新日期：1999-12-16 00:00:00

abstract：:Chromodomain on Y-like (CDYL) is a chromodomain protein that has sequence homology to members of the enoyl CoA hydratase family. Although the chromodomain of CDYL has been implicated in chromatin remodeling during mammalian spermatogenesis, the function of the Cdyl gene remains unclear. Recently, induced pluripotent s...

journal_title：Neuroreport

authors： Wan L,Hu XJ,Yan SX,Chen F,Cai B,Zhang XM,Wang T,Yu XB,Xiang AP,Li WQ

更新日期：2013-02-13 00:00:00

abstract：:Human scalp EEG has demonstrated that global coherence among distant areas increases during cognitive tasks, suggesting that oscillating neural activities work to generate global neuronal assemblies for cognitive functions. The theta oscillation in a frequency range of 4-8 Hz with large amplitudes which emerges during...

journal_title：Neuroreport

authors： Mizuhara H,Wang LQ,Kobayashi K,Yamaguchi Y

更新日期：2004-06-07 00:00:00

abstract：:Benevolence is widespread in our societies. It is defined as considering a subordinate group nicely but condescendingly, that is, with charity. Deleterious consequences for the target have been reported in the literature. In this experiment, we used functional MRI (fMRI) to identify whether being the target of (sexist...

journal_title：Neuroreport

authors： Dardenne B,Dumont M,Sarlet M,Phillips C,Balteau E,Degueldre C,Luxen A,Salmon E,Maquet P,Collette F

更新日期：2013-07-10 00:00:00

abstract：:The relation between neuronal activity in the superior parietal lobule with working memory capacity in an elderly population was investigated. Using functional magnetic resonance imaging we examined effects associated with the performance of a reading span test and individual differences in executive function and shor...

journal_title：Neuroreport

authors： Otsuka Y,Osaka N,Osaka M

更新日期：2008-09-17 00:00:00

abstract：:Neuronotrophic factors (e.g. basic fibroblast growth factor, bFGF and nerve growth factor, NGF) have been demonstrated to respectively promote survival and neuritogenesis in cultures of dissociated adult rat spiral ganglia. Transforming growth factor beta (TGF beta 1) has been shown to modulate the response of culture...

journal_title：Neuroreport

authors： Lefebvre PP,Martin D,Staecker H,Weber T,Moonen G,Van de Water TR

更新日期：1992-04-01 00:00:00

abstract：:The organization of the main olfactory bulb of an insectivore, the laboratory shrew (Suncus murinus), was studied morphologically. We found particular small spherical regions, nidi, at the border between the glomerular and external plexiform layer (EPL), which were intensely GAD positive, 30-60 microm in diameter, and...

journal_title：Neuroreport

authors： Kosaka K,Kosaka T

更新日期：1999-02-05 00:00:00

abstract：:Emerging evidence has suggested that alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) protects neurons from glutamate-induced neurotoxicity. In this study, we examined the effect of AMPA on the cell surface expression of the N-methyl-D-aspartate (NMDA) receptor, a central player in glutamate-induced neurot...

journal_title：Neuroreport

authors： Nishimoto T,Kihara T,Akaike A,Niidome T,Sugimoto H

更新日期：2009-01-28 00:00:00

abstract：:SCN1A gene mutations are associated with epilepsy and neurodevelopmental disorders. This study aimed to explore the genotype and phenotype spectrum of SCN1A gene related epilepsy. Epileptic patients who were treated in the Children's Hospital of Chongqing Medical University from January 2015 to July 2018 and identifie...

journal_title：Neuroreport

authors： Fang ZX,Hong SQ,Li TS,Wang J,Xie LL,Han W,Jiang L

更新日期：2019-06-12 00:00:00

abstract：:The serotonin transporter is a strong candidate for aetiological involvement in affective disorders and psychosis. We analysed a VNTR in intron 2 of the human serotonin transporter gene (hSERT) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. An increased frequency of all...

journal_title：Neuroreport

authors： Collier DA,Arranz MJ,Sham P,Battersby S,Vallada H,Gill P,Aitchison KJ,Sodhi M,Li T,Roberts GW,Smith B,Morton J,Murray RM,Smith D,Kirov G

更新日期：1996-07-08 00:00:00

abstract：:Prepulse inhibition (PPI) and reactivity of the acoustic startle response are widely used biobehavioral markers in psychopathology research. Previous studies have demonstrated that PPI and startle reactivity exhibit substantial within-site stability; however, between-site stability has not been established. In two sep...

journal_title：Neuroreport

authors： Cadenhead KS,Addington J,Cannon TD,Cornblatt BA,de la Fuente-Sandoval C,Mathalon DH,Perkins DO,Seidman LJ,Tsuang M,Walker EF,Woods SW,Bachman P,Belger A,Carrión RE,Donkers FC,Duncan E,Johannesen J,León-Ortiz P,Light G

更新日期：2013-08-07 00:00:00

abstract：:To determine whether physical match between studied and tested items influences blood flow increases in the hippocampal formation associated with recognition memory, positron emission tomography (PET) was used to measure changes in regional cerebral blood flow while healthy volunteers made old/new judgements about lin...

journal_title：Neuroreport

authors： Schacter DL,Uecker A,Reiman E,Yun LS,Bandy D,Chen K,Cooper LA,Curran T

更新日期：1997-12-22 00:00:00

abstract：:Axotomy-induced death of corticospinal neurons (CSN) is prevented by intracotrical infusions of BDNF or NT-3 within the first week after axotomy. The present study examined whether this represents merely a delay of CSN death or whether BDNF and NT-3 can promote long-term survival of these neurons in vivo. The neurotro...

journal_title：Neuroreport

authors： Hammond EN,Tetzlaff W,Mestres P,Giehl KM

更新日期：1999-08-20 00:00:00

abstract：:This study examined the effects of cocaine HCl and ambient temperature on the core body temperature of the rat. To further examine the mechanisms of cocaine-induced changes in temperature regulation, the effects of cocaine on behavioral thermoregulatory responses were also observed. At normal room temperature (20 degr...

journal_title：Neuroreport

authors： Gonzalez LP

更新日期：1993-01-01 00:00:00

abstract：:In mammals, cytosine methylation is important for the regulation of gene expression and chromatin structure. Recently, we have found evidence indicating that the maintained DNA methyltransferase activity is critical for neuronal cell differentiation. In the present study, we have investigated the effect of the DNA met...

journal_title：Neuroreport

authors： Persengiev SP,Kilpatrick DL

更新日期：1997-07-07 00:00:00

abstract：:This study tested whether adult rat brain stem neurons could respond to growth or trophic factors provided after an extended post-injury period. The number of neurons that regenerated their axon into a peripheral nerve graft following exposure to ciliary neurotrophic factor (CNTF) 8 weeks after a cervical lesion was c...

journal_title：Neuroreport

authors： Houle JD,Ye JH

更新日期：1997-02-10 00:00:00

abstract：:We investigated the expression for fibroblast growth factor-2 (FGF-2), in cultured rat cerebellar granule cells and its modulation by Ca2+ regulating agents. There were no significant differences in the levels of FGF-2 mRNA in cells cultured in high vs low K+. The expression of the trophic factor is induced by Ca2+ en...

journal_title：Neuroreport

authors： Roceri M,Molteni R,Racagni G,Riva MA

更新日期：2000-11-09 00:00:00

abstract：:Homotopic and isochronic transplantation of the alar plate of the rhombomeres 7 and 8 was performed between chick and quail embryos at the stage of 10-14 somites. Analysis of the graft derivatives in 12-day-old chimeric embryos by means of the quail nucleolar marker showed that the ipsilateral inferior olive is formed...

journal_title：Neuroreport

authors： Ambrosiani J,Armengol JA,Martinez S,Puelles L

更新日期：1996-05-17 00:00:00

abstract：OBJECTIVE:This study aimed to observe the effect of glutamine (Gln) on brain damage in septic rats and explore its possible mechanism. METHODS:Ninety-three Sprague-Dawley rats were randomly divided into five groups: sham operation group, sepsis group, Gln-treated group, quercetin/Gln-treated group, and alloxan/Gln-tre...

journal_title：Neuroreport

authors： Wang J,Lu X,Zheng K,Jing L

更新日期：2021-01-18 00:00:00

abstract：:The steady-state visual evoked potential (SSVEP) is a powerful tool to study basic perceptual functions in the human electroencephalogram (EEG) (e.g. selective attention). The present study aimed at finding support for the SSVEP's sensitivity to higher cognitive functions (e.g. memory). We tagged pictures of meaningle...

journal_title：Neuroreport

authors： Martens U,Gert AL,Gruber T

更新日期：2012-04-18 00:00:00