Abstract：
:Japanese encephalitis virus (JEV) is an arbovirus belonging to the family Flaviviridae. It is maintained in a zoonotic cycle involving pigs, ardeid birds and Culex species of mosquitoes. Humans are accidental/dead end hosts of JEV infection because they cannot sustain high viral titers. Factors affecting the clinical manifestations and pathogenesis of JEV infection are not well understood. Though, vaccines are currently available against JEV, it has to be further improved. Here we review the literature on the JEV life cycle, pathogenesis and host immune responses to JEV infection.
journal_name
Microbes Infectjournal_title
Microbes and infectionauthors
Unni SK,Růžek D,Chhatbar C,Mishra R,Johri MK,Singh SKdoi
10.1016/j.micinf.2011.01.002subject
Has Abstractpub_date
2011-04-01 00:00:00pages
312-21issue
4eissn
1286-4579issn
1769-714Xpii
S1286-4579(11)00018-9journal_volume
13pub_type
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