Abstract:
:Yersiniabactin (Ybt) is a siderophore-dependent iron uptake system encoded on a pathogenicity island that is widespread among pathogenic bacteria including the Yersiniae. While biosynthesis of the siderophore has been elucidated, the secretion mechanism and a few components of the uptake/utilization pathway are unidentified. ybt genes are transcriptionally repressed by Fur but activated by YbtA, likely in combination with the siderophore itself. The Ybt system is essential for the ability of Yersinia pestis to cause bubonic plague and important in pneumonic plague as well. However, the ability to cause fatal septicemic plague is independent of Ybt.
journal_name
Microbes Infectjournal_title
Microbes and infectionauthors
Perry RD,Fetherston JDdoi
10.1016/j.micinf.2011.04.008subject
Has Abstractpub_date
2011-09-01 00:00:00pages
808-17issue
10eissn
1286-4579issn
1769-714Xpii
S1286-4579(11)00116-Xjournal_volume
13pub_type
杂志文章,评审abstract::Microbes use numerous strategies to invade the central nervous system. Leukocyte-facilitated entry is one such mechanism whereby intracellular pathogens establish infection by taking advantage of leukocyte trafficking to the central nervous system. Key components of this process include peripheral infection and activa...
journal_title:Microbes and infection
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journal_title:Microbes and infection
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journal_title:Microbes and infection
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journal_title:Microbes and infection
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journal_title:Microbes and infection
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更新日期:2017-01-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章
doi:10.1016/j.micinf.2011.06.002
更新日期:2011-11-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章,评审
doi:10.1016/j.micinf.2006.04.009
更新日期:2006-07-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章
doi:10.1016/s1286-4579(00)00366-x
更新日期:2000-05-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章
doi:10.1016/j.micinf.2004.11.007
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journal_title:Microbes and infection
pub_type: 杂志文章,评审
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更新日期:2012-12-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章
doi:10.1016/j.micinf.2004.01.009
更新日期:2004-04-01 00:00:00
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journal_title:Microbes and infection
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doi:10.1016/j.micinf.2017.11.003
更新日期:2018-03-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章
doi:10.1016/j.micinf.2008.07.009
更新日期:2008-07-01 00:00:00
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journal_title:Microbes and infection
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doi:10.1016/j.micinf.2008.01.001
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更新日期:1999-08-01 00:00:00
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journal_title:Microbes and infection
pub_type: 杂志文章
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journal_title:Microbes and infection
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journal_title:Microbes and infection
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journal_title:Microbes and infection
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journal_title:Microbes and infection
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journal_title:Microbes and infection
pub_type: 杂志文章,评审
doi:10.1016/j.micinf.2004.05.002
更新日期:2004-08-01 00:00:00
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