From the patient perspective: the economic value of seasonal and H1N1 influenza vaccination.

abstract：:Financial sustainability plans (FSPs) were developed by over 50 of the world's poorest countries receiving funding support from the Global Alliance for Vaccines and Immunization (GAVI) to introduce new and underused vaccines, injection safety and immunization service support between 2000 and 2006. These plans were ana...

journal_title：Vaccine

authors： Kamara L,Milstien JB,Patyna M,Lydon P,Levin A,Brenzel L

更新日期：2008-12-02 00:00:00

abstract：:The human adenovirus type 19a/64 (hAd19a) is a rare serotype in the human population that transduces human dendritic cells (DCs) and human muscle cells more efficiently than the well-characterized human adenovirus type 5 (hAd5). To further characterize the potential of this vector as a vaccine we designed replication ...

journal_title：Vaccine

authors： Ragonnaud E,Schroedel S,Mariya S,Iskandriati D,Pamungkas J,Fougeroux C,Daradoumis J,Thomsen AR,Neukirch L,Ruzsics Z,Salomon M,Thirion C,Holst PJ

更新日期：2018-10-01 00:00:00

abstract：:Antigens protective against Ixodes scapularis infestations were identified by cDNA expression library immunization (ELI) and analysis of expressed sequenced tags (EST). Three cDNAs protective against larval tick infestations, 4F8, with homology to a nucleotidase, and 4D8 and 4E6 of unknown function, were characterized...

journal_title：Vaccine

authors： Almazán C,Kocan KM,Blouin EF,de la Fuente J

更新日期：2005-11-16 00:00:00

abstract：:H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing the need for a broadly protective influenza vaccine. Here, we constructed BV-Dual-3M2e-LTB, a recombinant baculo...

journal_title：Vaccine

authors： Zhang J,Fan HY,Zhang Z,Zhang J,Zhang J,Huang JN,Ye Y,Liao M

更新日期：2016-01-27 00:00:00

abstract：:Although West Nile virus (WNV) causes annual cases of neurological disease and deaths in humans, a vaccine has not been licensed for human use. Several WNV genes have been targeted for mutagenesis in attempts to generate live attenuated vaccine candidates, including the non-structural protein NS5. Specifically, mutati...

journal_title：Vaccine

authors： Kaiser JA,Luo H,Widen SG,Wood TG,Huang CY,Wang T,Barrett ADT

更新日期：2019-11-15 00:00:00

abstract：:Pneumococcal conjugate vaccines (PCV) may reduce nasopharyngeal carriage (NPC) of Streptococcus pneumoniae vaccine strains (VT), but serotype replacement with non-vaccine strains (NVT) has been reported. Bacterial NPC after PHiD-CV vaccination was assessed in the second year of life. Open descriptive study of NPC repo...

journal_title：Vaccine

authors： Prymula R,Hanovcova I,Splino M,Kriz P,Motlova J,Lebedova V,Lommel P,Kaliskova E,Pascal T,Borys D,Schuerman L

更新日期：2011-02-24 00:00:00

abstract：:Respiratory syncytial virus (RSV) causes severe respiratory illness in infants. There are no licensed vaccines to prevent RSV infection. The neonate receives short-term protection from maternally derived antibodies, which, however, can also interfere with the active response to vaccination. A RSV vaccine consisting of...

journal_title：Vaccine

authors： Garg R,Latimer L,Gerdts V,Potter A,van Drunen Littel-van den Hurk S

更新日期：2015-03-10 00:00:00

abstract：:Because of delays in the manufacturing of the 2000-2001, trivalent inactivated influenza vaccine in the US, there were concerns that there might be shortages of vaccine supply in the US. Therefore, we conducted a prospective, randomized, open-label, multicenter trial at six academic medical centers in the US, to evalu...

journal_title：Vaccine

authors： Treanor J,Keitel W,Belshe R,Campbell J,Schiff G,Zangwill K,Wolff M,Klimov A,Levandowski R,Lambert L

更新日期：2002-01-15 00:00:00

abstract：:Optimized DNA vectors were constructed comprising the proteome of SIV including the structural, enzymatic, regulatory, and accessory proteins. In addition to native antigens as produced by the virus, fusion proteins and modified antigens with altered secretion, cellular localization and stability characteristics were ...

journal_title：Vaccine

authors： Kulkarni V,Jalah R,Ganneru B,Bergamaschi C,Alicea C,von Gegerfelt A,Patel V,Zhang GM,Chowdhury B,Broderick KE,Sardesai NY,Valentin A,Rosati M,Felber BK,Pavlakis GN

更新日期：2011-09-09 00:00:00

abstract：:Following routine childhood vaccination against Haemophilus influenzae type b (Hib) disease in Brazil in 1999, passive laboratory surveillance reported increasing numbers of non-b serotypes and nontypeable H. influenzae (NTHi) from meningitis cases. To characterize this increase, we analyzed data on 3910 H. influenzae...

journal_title：Vaccine

authors： Zanella RC,Bokermann S,Andrade AL,Flannery B,Brandileone MC

更新日期：2011-11-08 00:00:00

abstract：:Paediatric patients with antibody deficiency may either be delayed in development of humoral immunity or may be persistently deficient in antibody production. To differentiate between these entities, we examined the 23-valent pneumococcal polysaccharide (PnPS) vaccine-induced IgM-, IgG- and IgA antibody responses in a...

journal_title：Vaccine

authors： Janssen WJ,Nierkens S,Sanders EA,Boes M,van Montfrans JM

更新日期：2015-11-17 00:00:00

abstract：:Immunization with Mycobacterium bovis Bacille Calmette-Guerin (BCG) did not induce adequate Th1 responses to the latency antigen, HspX of M. tuberculosis. To increase the immunogenicity and protective efficacy of BCG, a recombinant BCG strain over-expressing antigen HspX (rBCG::X) was constructed. The recombinant stra...

journal_title：Vaccine

authors： Shi C,Chen L,Chen Z,Zhang Y,Zhou Z,Lu J,Fu R,Wang C,Fang Z,Fan X

更新日期：2010-07-19 00:00:00

abstract：:The expression and secretion of pertussis toxin subunits S1 to S5 in Bacillus subtilis by the aid of a bacillary signal sequence has been reported. While secretion of subunit S1 was high, that of others was low. Ways have now been explored to improve the yield, using S4 as an example. The addition of a protease inhibi...

journal_title：Vaccine

authors： Himanen JP,Taira S,Sarvas M,Saris P,Runeberg-Nyman K

更新日期：1990-12-01 00:00:00

abstract：:As a step in the development of an oral vaccine against ETEC, we evaluated the safety and immunogenicity of CS6, a polymeric protein commonly found on the surface of ETEC. Formulations included 1 and 5mg doses of CS6, either encapsulated in biodegradable polymer poly(D, L)-lactide-co-glycolide (PLG), or as free protei...

journal_title：Vaccine

authors： Katz DE,DeLorimier AJ,Wolf MK,Hall ER,Cassels FJ,van Hamont JE,Newcomer RL,Davachi MA,Taylor DN,McQueen CE

更新日期：2003-01-17 00:00:00

abstract：BACKGROUND:In January 2015, Tajikistan introduced the monovalent rotavirus vaccine into the national immunization program. Our objective was to estimate pre-vaccine burden of rotavirus-associated hospitalizations in children <5 years of age in Tajikistan. METHODS:During January 2013-December 2014, active surveillance ...

journal_title：Vaccine

authors： Nazurdinov AB,Azizov ZA,Tishkova F,Turkov SM,Daniels DS,Leshem E

更新日期：2018-12-14 00:00:00

abstract：:The field of vaccinology is increasingly moving toward the generation, analysis, and modeling of extremely large and complex high-dimensional datasets. We have used data such as these in the development and advancement of the field of vaccinomics to enable prediction of vaccine responses and to develop new vaccine can...

journal_title：Vaccine

authors： Oberg AL,McKinney BA,Schaid DJ,Pankratz VS,Kennedy RB,Poland GA

更新日期：2015-09-29 00:00:00

abstract：:The target animals and vaccination regimes for vaccines against the bovine rhinotracheitis (IBR) and the bovine viral diarrhoea virus (BVDV) are very similar. Therefore, we have compared different schedules for the combined use of a live IBR marker vaccine and an inactivated BVD vaccine. The neutralizing antibody resp...

journal_title：Vaccine

authors： Alvarez M,Bielsa JM,Santos L,Makoschey B

更新日期：2007-09-04 00:00:00

abstract：:There has been controversy about whether cognitive changes occur in early human immunodeficiency virus (HIV) disease. In those studies reporting cognitive changes, these are typically subclinical, and their relationship to daily and/or occupational functioning has not been addressed. The potential effects of changes m...

journal_title：Vaccine

authors： Mapou RL,Rundell JR,Kay GG,Tramont EC

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The effectiveness of inactivated influenza vaccine (IIV) immunization in preventing all cause respiratory illness (RI) in children with pre-existing medical conditions has not been fully established and varies from season to season. This study aims to quantify the overall impact of IIV immunization on primar...

journal_title：Vaccine

authors： de Hoog MLA,Venekamp RP,Meijer A,Sanders EAM,Bruijning-Verhagen PCJL

更新日期：2020-04-09 00:00:00

abstract：:Oral administration of antigen is known to be appropriate for some vaccine purposes as well as oral tolerance induction. In the present study, oral administration of beta-lactoglobulin (BLG) loaded poly(D,L-lactide-co-glycolide) (D,L-PLG) microspheres induced tolerance was evaluated. A single feeding of 5 micrograms o...

journal_title：Vaccine

authors： Pecquet S,Leo E,Fritsché R,Pfeifer A,Couvreur P,Fattal E

更新日期：2000-01-18 00:00:00

abstract：:This report reflects the discussion and conclusions of a WHO group of experts from National Regulatory Authorities (NRAs), National Control Laboratories (NCLs), vaccine industries and other relevant institutions involved in standardization and control of diphtheria, tetanus and pertussis vaccines (DTP), held on 20-21 ...

journal_title：Vaccine

authors： Corbel MJ,Das RG,Lei D,Xing DK,Horiuchi Y,Dobbelaer R,WHO Working Group.

更新日期：2008-04-07 00:00:00

abstract：:A phase III, randomized, double-blind study evaluated the efficacy, reactogenicity, safety and immunogenicity of a human rotavirus vaccine, RIX4414 in Japanese infants aged 6-14 weeks when administered as two doses (0, 1-month schedule). Efficacy against any and severe rotavirus gastroenteritis leading to medical inte...

journal_title：Vaccine

authors： Kawamura N,Tokoeda Y,Oshima M,Okahata H,Tsutsumi H,Van Doorn LJ,Muto H,Smolenov I,Suryakiran PV,Han HH

更新日期：2011-08-26 00:00:00

abstract：:We previously demonstrated that intradermal and intramuscular vaccination with Leishmania amazonensis promastigote antigens (LaAg) increases the susceptibility of BALB/c mice to cutaneous leishmaniasis. In this study, we investigated the role played by serine and cysteine proteases as disease-promoting components of L...

journal_title：Vaccine

authors： de Matos Guedes HL,Pinheiro RO,Chaves SP,De-Simone SG,Rossi-Bergmann B

更新日期：2010-07-26 00:00:00

abstract：:Haemophilus parasuis (H. parasuis) is a swine pathogen responsible for the Glässer's disease, which has received more attention in the past decade due to the increasing economic losses in the pig industry worldwide. As traditional inactive vaccine of H. parasuis has obvious disadvantage, to identify efficient immunopr...

journal_title：Vaccine

authors： Li M,Song S,Yang D,Li C,Li G

更新日期：2015-03-30 00:00:00

abstract：:Two H1N1 progeny viruses derived by mating the attenuated donor virus, the A/Ningxia/72-ts (H3N2), and the A/Beijing/70 (H1N1) wild type virus were characterized for their genotype and their level of attenuation in susceptible adult volunteers. One progeny virus, clone PX62, was not a reassortant since it received eac...

journal_title：Vaccine

authors： Tian SF,Zhang LX,Murphy BR

更新日期：1984-09-01 00:00:00

abstract：:Amid provider reports of financial barriers as an impediment to adult immunization, this study explores the time and costs of vaccination in adult provider practices. Both a Vaccination Time-Motion Study and Vaccine Practice Management Survey were conducted (March - October 2017) in a convenience sample of 19 family m...

journal_title：Vaccine

authors： Shen A,Khavjou O,King G,Bates L,Zhou F,Leidner AJ,Yarnoff B

更新日期：2019-02-04 00:00:00

abstract：:Capsular polysaccharides of Streptococcus pneumoniae are used to formulate polyvalent pneumococcal vaccines. A sensitive method, using high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD), has been developed to quantify the contamination of pneumococcal capsular polysaccharides...

journal_title：Vaccine

authors： Talaga P,Bellamy L,Moreau M

更新日期：2001-04-06 00:00:00

abstract：:In a Phase 2a trial of the RTS,S/AS vaccine, we described significant association between protection against infection and vaccine-induced CD4 T cells. To determine whether processing of the circumsporozoite protein as a component of the RTS,S particulate antigen yields the same HLA-DR-restricted epitopes as those rec...

journal_title：Vaccine

authors： Schwenk R,Lumsden JM,Rein LE,Juompan L,Kester KE,Heppner DG,Krzych U

更新日期：2011-11-08 00:00:00

abstract：:The potential outcomes of a Phase II schistosomiasis vaccine trial are explored using mathematical models which assume some natural immunity and a vaccine providing partial protection for a limited time. Analyses suggest that vaccination may have only a limited impact on life-long cumulative worm burdens and may lead ...

journal_title：Vaccine

authors： Woolhouse ME

更新日期：1995-08-01 00:00:00

abstract：INTRODUCTION:We performed a pooled analysis of randomised clinical trials (RCT) on HPV vaccine efficacy in preventing cervical persistent infection. METHODS:We carried out a bibliographic search on electronic databases and we selected RCT to perform the meta-analyses. RESULTS:We selected five studies. The first meta-...

journal_title：Vaccine

authors： La Torre G,de Waure C,Chiaradia G,Mannocci A,Ricciardi W

更新日期：2007-12-05 00:00:00