Relating cognitive function to military aviator performance in early HIV infection.

abstract：:Post-licensure vaccine safety studies often monitor for seizures using automated screening of ICD-9 codes. This study assessed the positive predictive value (PPV) of ICD-9 codes used to identify seizure visits in children aged 6 weeks to 23 months who were enrolled in seven managed care organizations during January 20...

journal_title：Vaccine

authors： Shui IM,Shi P,Dutta-Linn MM,Weintraub ES,Hambidge SJ,Nordin JD,Lieu TA,Vaccine Safety Datalink Research Team.

更新日期：2009-08-27 00:00:00

abstract：:Cell culture-based manufacturing of influenza vaccines is ideally based on easily scalable platforms using suspension cells that grow in chemically defined media. Consequently, different adherent cell lines selected for high virus yields were adapted to grow in suspension culture. This includes the MDCK suspension cel...

journal_title：Vaccine

authors： Peschel B,Frentzel S,Laske T,Genzel Y,Reichl U

更新日期：2013-11-19 00:00:00

abstract：:Enterobactin (Ent)-mediated high affinity iron acquisition is critically important for Gram-negative bacterial pathogens to survive and infect the host. Recently, we reported an efficient method to prepare novel Ent conjugate vaccines for inducing high level of Ent-specific antibodies, which displayed similar bacterio...

journal_title：Vaccine

authors： Wang H,Zeng X,Lin J

更新日期：2020-11-17 00:00:00

abstract：:Reconstituted influenza virus (A/PR/8 strain) envelopes (RIVE) and influenza virus (A/Sichuan/87 (H3N2) strain) surface antigens were entrapped in dehydration-rehydration vesicles (DRV liposomes) composed of egg phosphatidylcholine (PC) or distearoyl phosphatidylcholine (DSPC DRV) and equimolar (32 mumol) cholesterol....

journal_title：Vaccine

authors： Gregoriadis G,Tan L,Ben-Ahmeida ET,Jennings R

更新日期：1992-01-01 00:00:00

abstract：:Enterohemorrhagic Escherichia coli (EHEC) comprise an important group of enteric pathogens causing hemorrhagic colitis and hemolytic uremic syndrome. These bacteria need EspA (E) as a conduct for Tir (T) delivery to the host cell and surface arrayed intimin (I) which docks the bacterium to the translocated Tir. This p...

journal_title：Vaccine

authors： Amani J,Salmanian AH,Rafati S,Mousavi SL

更新日期：2010-10-04 00:00:00

abstract：:The development of effective vaccines against serogroup B meningococci is of great public health importance. We assessed a novel genetically engineered vaccine containing six meningococcal class 1 (PorA) outer membrane proteins representing 80% of prevalent strains in the UK. 103 infants were given the meningococcal v...

journal_title：Vaccine

authors： Cartwright K,Morris R,Rümke H,Fox A,Borrow R,Begg N,Richmond P,Poolman J

更新日期：1999-06-04 00:00:00

abstract：:Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines. Here we used a rabbit model to compare quantitatively and qualitatively the antibody responses induced by poly(D,L-lactide) nanoparticles (PLA) and by emulsion adjuvant MF59 using three HIV-1 antigens: p24ga...

journal_title：Vaccine

authors： Guillon C,Mayol K,Terrat C,Compagnon C,Primard C,Charles MH,Delair T,Munier S,Verrier B

更新日期：2007-10-23 00:00:00

abstract：:Recent studies have revealed that the interface of gp120 and gp41 and some parts of gp41 are also critical epitopes for elicitation of broadly neutralizing antibodies. Therefore, potential trimeric gp41 or gp140 immunogen candidates are needed. Previously, we developed a trimer motif MTQ and demonstrated that it could...

journal_title：Vaccine

authors： Yao L,Wang JY,Bao LN,Fan MX,Bai Y,Chen WJ,Yuan C,Yuan L,Wang J,Li Y,Zhuang M,Ling H

更新日期：2020-11-03 00:00:00

abstract：:A post hoc analysis was performed using combined data from two Phase I tolerability/immunogenicity studies of monovalent human papillomavirus type 11 (HPV11) or HPV16 L1 virus-like particle (VLP) vaccines. The goal was to determine if the HPV16 L1 VLP vaccine protected against HPV16 infection. Vaccine or placebo was g...

journal_title：Vaccine

authors： Brown DR,Fife KH,Wheeler CM,Koutsky LA,Lupinacci LM,Railkar R,Suhr G,Barr E,Dicello A,Li W,Smith JF,Tadesse A,Jansen KU

更新日期：2004-07-29 00:00:00

abstract：:Prior work shows that an attenuated West Nile virus (WNV), the nonstructural (NS)4B-P38G mutant infection in mice induced strong immune responses and protected host from subsequent lethal wild-type WNV infection. Here, we investigated NS4B-P38G mutant infection in myeloid differentiation factor 88-deficient (MyD88(-/-...

journal_title：Vaccine

authors： Xie G,Welte T,Wang J,Whiteman MC,Wicker JA,Saxena V,Cong Y,Barrett AD,Wang T

更新日期：2013-08-28 00:00:00

abstract：:Biodegradable microspheres (MS) based on poly(D,L-lactide) and poly(D,L-lactide-coglycolide) have the capacity to release encapsulated antigens over defined lengths of time depending on their composition and to elicit and sustain strong and long-lasting immune responses to protein antigens. In the present study, two s...

journal_title：Vaccine

authors： Men Y,Gander B,Merkle HP,Corradin G

更新日期：1996-10-01 00:00:00

abstract：:There is an emerging interest to develop human vaccines against medically-important fungal pathogens and a need for a preclinical animal model to assess vaccine efficacies and protective correlates. HLA-DR4 (DRB1∗0401 allele) transgenic mice express a human major histocompatibility complex class II (MHC II) receptor i...

journal_title：Vaccine

authors： Hurtgen BJ,Castro-Lopez N,Jiménez-Alzate MDP,Cole GT,Hung CY

更新日期：2016-10-17 00:00:00

abstract：:Many influenza vaccines targeted to hemagglutinin (HA) show efficient immunogenicity for protecting subjects against influenza virus infection. Major antigenic changes to HA molecules can help influenza virus to develop resistance against HA-targeted vaccines. DNA vaccines encoding conserved antigens protect animals a...

journal_title：Vaccine

authors： Ohba K,Yoshida S,Zahidunnabi Dewan M,Shimura H,Sakamaki N,Takeshita F,Yamamoto N,Okuda K

更新日期：2007-05-22 00:00:00

abstract：:Recombinant hepatitis B vaccine has been used widely in the world since 1991. The side effects of hepatitis B vaccine are seen rarely. In this paper, we present clinical and laboratory progress of an infant who gets severe thrombocytopenia after the second dosage hepatitis B vaccine. Our case is different from other c...

journal_title：Vaccine

authors： Polat A,Akca H,Dagdeviren E

更新日期：2008-12-02 00:00:00

abstract：:In a previous study, children 18 to 36 months of age and seropositive for respiratory syncytial virus (RSV) were vaccinated with an RSV subunit vaccine (PFP-1) consisting of the viral fusion protein. Vaccines developed substantial increases in anti-fusion and neutralizing antibody and exhibited protection against RSV ...

journal_title：Vaccine

authors： Tristram DA,Welliver RC,Hogerman DA,Hildreth SW,Paradiso P

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Pandemic planning has historically been oriented to respond to an influenza virus, with vaccination strategy being a key focus. As the current COVID-19 pandemic plays out, the Australian government is closely monitoring progress towards development of SARS-CoV2 vaccines as a definitive intervention. However,...

journal_title：Vaccine

authors： Degeling C,Williams J,Carter SM,Moss R,Massey P,Gilbert GL,Shih P,Braunack-Mayer A,Crooks K,Brown D,McVernon J

更新日期：2021-01-08 00:00:00

abstract：:Cholera toxin B subunit (CTB) and Escherichia coli heat-labile toxin (LTB) (2 micrograms), each supplemented with a trace amount of cholera toxin (CT) (0.02-20 ng), were examined for the adjuvant effect on antibody (Ab) response against influenza inactivated HA (haemagglutinin) vaccine in Balb/c mice. Each mouse recei...

journal_title：Vaccine

authors： Tamura S,Yamanaka A,Shimohara M,Tomita T,Komase K,Tsuda Y,Suzuki Y,Nagamine T,Kawahara K,Danbara H

更新日期：1994-04-01 00:00:00

abstract：:This study uses a dynamic influenza transmission model to directly compare the cost-effectiveness of various policies of annual paediatric influenza vaccination in England and Wales, varying the target age range and level of coverage. The model accounts for both the protection of those immunised and the indirect prote...

journal_title：Vaccine

authors： Pitman RJ,Nagy LD,Sculpher MJ

更新日期：2013-01-30 00:00:00

abstract：BACKGROUND:In Bogotá, the Heptavalent Conjugate Vaccine (PCV7) was introduced into childhood immunization schedule since 2009. The aim of this study was to assess the changes in serotype distribution and penicillin susceptibility of Streptococcus pneumoniae isolates recovered from nasopharyngeal samples and invasive di...

journal_title：Vaccine

authors： Parra EL,De La Hoz F,Díaz PL,Sanabria O,Realpe ME,Moreno J

更新日期：2013-08-20 00:00:00

abstract：:The live bacterial vaccine Mycobacterium bovis BCG (BCG) is a vehicle worth noticing for various protective antigens. The gene encoding the B-cell epitope of the oligopeptide repeating in the circumsporozoite protein (C.S. protein) of the rodent malaria parasite, Plasmodium yoelii, was inserted into the plasmid vector...

journal_title：Vaccine

authors： Matsumoto S,Yanagi T,Ohara N,Wada N,Kanbara H,Yamada T

更新日期：1996-01-01 00:00:00

abstract：:By using a baculovirus expression system, we have successfully produced simian immunodeficiency virus (SIV)-like particles (VLPs) with high levels of biologically active SIV envelope (Env) incorporated on their surfaces. To study whether SIV VLPs represent effective mucosal immunogens, we immunized groups of mice with...

journal_title：Vaccine

authors： Yao Q,Vuong V,Li M,Compans RW

更新日期：2002-06-07 00:00:00

abstract：BACKGROUND:Elimination of congenital rubella syndrome depends not only on effective childhood immunization but also on the identification and immunization of rubella susceptible women. We assessed rubella susceptibility among pregnant women and evaluated the adherence and response to postpartum immunization with measle...

journal_title：Vaccine

authors： Vilajeliu A,García-Basteiro AL,Valencia S,Barreales S,Oliveras L,Calvente V,Goncé A,Bayas JM

更新日期：2015-04-08 00:00:00

abstract：:Vaccines utilizing poorly immunogenic subunit antigens are dependent upon adjuvants to drive the appropriate T cell responses. In an effort to determine the ability of several adjuvants to promote cell-mediated immunity (CMI), we assessed delayed-type hypersensitivity (DTH) in mice inoculated with heat-killed Listeria...

journal_title：Vaccine

authors： Baldridge JR,Ward JR

更新日期：1997-03-01 00:00:00

abstract：:Vector-directed lymphokine expression represents a novel approach to the attenuation of live recombinant viruses which might be used as vaccines. Expression of interleukin-2 (IL-2) by recombinant vaccinia virus has been shown to significantly attenuate virus virulence in rodent species without diminishing immunogenici...

journal_title：Vaccine

authors： Flexner C,Moss B,London WT,Murphy BR

更新日期：1990-02-01 00:00:00

abstract：:The immunoscreening of Brugia malayi adult cDNA library with pooled endemic normal sera identified several seroreactive clones including, EC-SOD which contained a 612 bp insert and showed significant nucleotide and deduced amino acid sequence homologies with superoxide dismutase (SOD) of other nematode parasites. The ...

journal_title：Vaccine

authors： Dabir S,Dabir P,Goswami K,Reddy MV

更新日期：2008-07-04 00:00:00

abstract：:Recently the urgency of developing a pandemic influenza vaccine has lead to the re-evaluation of the use of whole virus vaccine. We have compared the humoral immune response and the protective efficacy of whole and split influenza virus vaccines in mice. Whole virus vaccine was more immunogenic particularly after the ...

journal_title：Vaccine

authors： Cox RJ,Hovden AO,Brokstad KA,Szyszko E,Madhun AS,Haaheim LR

更新日期：2006-11-10 00:00:00

abstract：:A reassortant virus possessing RNA segment 7, which codes for the M1 and M2 proteins, of the avian influenza A/Mallard/New York/6750/78 (H2N2) virus and the other seven RNA segments of the human influenza A/Udorn/307/72 (H3N2) virus had been shown previously to be markedly restricted in replication in the respiratory ...

journal_title：Vaccine

authors： Murphy BR,Buckler-White AJ,London WT,Snyder MH

更新日期：1989-12-01 00:00:00

abstract：:Prior to routine immunisation, Haemophilus influenzae serotype b (Hib) was a major cause of serious bacterial infections, particularly in young children. In the United Kingdom, introduction of the Hib conjugate vaccine into the national childhood immunisation schedule has led to a sustained decline in invasive Hib dis...

journal_title：Vaccine

authors： Townsend K,Ladhani SN,Findlow H,Borrow R

更新日期：2014-09-29 00:00:00

abstract：:Human adenoviruses (AdVs) have been extensively studied as vectors for gene therapy and vaccination. However, little attention has been paid to AdV vaccine development and treatment. Currently, there is a lack of information concerning the immunogenicity of AdV major capsid proteins. Here, using AdV7 as a model, we co...

journal_title：Vaccine

authors： Hu K,Fu M,Guan X,Zhang D,Deng X,Xiao Y,Chen R,Liu H,Hu Q

更新日期：2018-07-05 00:00:00

abstract：:Every year, meningococcal meningitis causes thousands of deaths within the meningitis belt in sub-Saharan African countries. Large epidemic waves occur with a periodicity of 5-12 years. The waves do correspond to molecular changes in the expression of capsular or subcapsular antigens, which allow the bug to spread in ...

journal_title：Vaccine

authors： Teyssou R,Muros-Le Rouzic E

更新日期：2007-09-03 00:00:00