Rotavirus hospitalizations among children

Abstract:

BACKGROUND:In January 2015, Tajikistan introduced the monovalent rotavirus vaccine into the national immunization program. Our objective was to estimate pre-vaccine burden of rotavirus-associated hospitalizations in children <5 years of age in Tajikistan. METHODS:During January 2013-December 2014, active surveillance for acute gastroenteritis (AGE)-associated hospitalizations in children <5 years of age was conducted by sentinel surveillance site staff. Patients' demographic and clinical data were summarized and a stool sample was collected. An Enzyme Linked Immunosorbent Assay was used for diagnosis of rotavirus infection and subset of the specimens was sent for polymerase chain reaction (PCR) genotyping. RESULTS:Of 2860 eligible children enrolled and tested, 1207 (42%) were positive for rotavirus. An increase in the number and proportion of rotavirus cases attributed to rotavirus season, with positivity rates >40%, was annually observed during June-September. The median age of rotavirus patients was 9 months and 939/1207 (78%) rotavirus patients were aged 6-23 months. Most (1097/1203; 91%) rotavirus patients were treated with intravenous fluids. G1P[8] was the predominant genotype during both years of surveillance, accounting for 133/222 (60%) of genotyped cases. CONCLUSION:Rotavirus is a major cause of hospitalization due to severe AGE in children <5 years of age in Tajikistan, accounting for >40% of cases. Continued, enhanced rotavirus surveillance may allow documentation of changes in rotavirus disease burden following vaccine introduction and assessment of vaccine effectiveness.

journal_name

Vaccine

journal_title

Vaccine

authors

Nazurdinov AB,Azizov ZA,Tishkova F,Turkov SM,Daniels DS,Leshem E

doi

10.1016/j.vaccine.2017.08.031

subject

Has Abstract

pub_date

2018-12-14 00:00:00

pages

7794-7797

issue

51

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(17)31115-5

journal_volume

36

pub_type

杂志文章

相关文献

VACCINE文献大全
  • N-fragment of edema factor as a candidate antigen for immunization against anthrax.

    abstract::The nontoxic N-terminal fragment of Bacillus anthracis edema factor (EF) was evaluated as a candidate antigen in an anthrax vaccine using a replication-incompetent adenoviral vector. An E1/E3 deleted adenovirus (Ad/EFn) encoding the N-terminal region 1-254 amino acids of the edema factor (EFn) was constructed using th...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.08.056

    authors: Zeng M,Xu Q,Hesek ED,Pichichero ME

    更新日期:2006-01-30 00:00:00

  • Humoral immunity against tick-borne encephalitis virus following manifest disease and active immunization.

    abstract::Humoral immunity against tick-borne encephalitis virus (TBEV) in patients with a well-documented history of naturally acquired tick-borne encephalitis (TBE) was compared with immunity resulting from vaccination in a carefully controlled immunization programme. The vaccination study was performed with a highly purified...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0264-410x(91)90315-w

    authors: Klockmann U,Bock HL,Kwasny H,Praus M,Cihlová V,Tomková E,Krivanec K

    更新日期:1991-01-01 00:00:00

  • Efficacy of a modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs naturally exposed to a heterologous European (Italian cluster) field strain: Clinical protection and cell-mediated immunity.

    abstract::The purpose of this study was to assess clinical protection in pigs vaccinated with a commercially available attenuated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine (Porcilis) PRRS) and then naturally exposed under field conditions to a heterologous (Italian cluster) strain of virulent PRRSV. A ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.03.028

    authors: Martelli P,Gozio S,Ferrari L,Rosina S,De Angelis E,Quintavalla C,Bottarelli E,Borghetti P

    更新日期:2009-06-08 00:00:00

  • Enterobactin-specific antibodies inhibit in vitro growth of different gram-negative bacterial pathogens.

    abstract::Enterobactin (Ent)-mediated high affinity iron acquisition is critically important for Gram-negative bacterial pathogens to survive and infect the host. Recently, we reported an efficient method to prepare novel Ent conjugate vaccines for inducing high level of Ent-specific antibodies, which displayed similar bacterio...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2020.10.040

    authors: Wang H,Zeng X,Lin J

    更新日期:2020-11-17 00:00:00

  • Efficacy of the oral pentavalent rotavirus vaccine in Mali.

    abstract::The oral, pentavalent rotavirus vaccine (PRV), RotaTeq was assessed for prevention of severe rotavirus gastroenteritis (RVGE) in young children in two multi-site, randomized, placebo-controlled field trials; one in Asia (Vietnam and Bangladesh) and the other in sub-Saharan Africa (Ghana, Kenya and Mali). The efficacy ...

    journal_title:Vaccine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.vaccine.2011.11.094

    authors: Sow SO,Tapia M,Haidara FC,Ciarlet M,Diallo F,Kodio M,Doumbia M,Dembélé RD,Traoré O,Onwuchekwa UU,Lewis KD,Victor JC,Steele AD,Neuzil KM,Kotloff KL,Levine MM

    更新日期:2012-04-27 00:00:00

  • Pneumococcal vaccination for splenectomized patients with thalassemia major in Indonesia.

    abstract:INTRODUCTION:Streptococcus pneumoniae is a capsulated bacterium that can cause severe infection in patients with thalassemia major, particularly those who have undergone splenectomy. The absence of the spleen as well as zinc deficiency in splenectomized patients with thalassemia major increases the possibility of devel...

    journal_title:Vaccine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.vaccine.2017.07.011

    authors: Sari TT,Akib AAP,Gatot D,Roswita Harahap A,Bardosono S,Hadinegoro SRS

    更新日期:2017-08-16 00:00:00

  • Foot-and-mouth disease vaccine potency testing in cattle using homologous and heterologous challenge strains: precision of the "Protection against Podal Generalisation" test.

    abstract::The level of protection conferred by foot-and-mouth disease (FMD) vaccines in primovaccinated animals primarily depends on the potency of the vaccine and the relatedness of the vaccine strain and circulating field isolate. The "Gold Standard" FMD vaccine potency test is the in vivo test performed in the target species...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2008.04.034

    authors: Goris N,Maradei E,D'Aloia R,Fondevila N,Mattion N,Perez A,Smitsaart E,Nauwynck HJ,La Torre J,Palma E,De Clercq K

    更新日期:2008-06-25 00:00:00

  • Adjuvant activity of immunopotentiating reconstituted influenza virosomes (IRIVs).

    abstract::Using immunopotentiating, reconstituted influenza virosomes (IRIV) as a delivery vehicle, a number of vaccines have been developed. In humans, IRIV-based vaccines containing hepatitis A and influenza antigens have been found to possess enhanced immunogenicity compared to alum-adsorbed vaccine for hepatitis A or commer...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(98)00440-x

    authors: Glück R

    更新日期:1999-03-26 00:00:00

  • The use of transgenic Plasmodium berghei expressing the Plasmodium vivax antigen P25 to determine the transmission-blocking activity of sera from malaria vaccine trials.

    abstract::P25 is a major surface protein of Plasmodium ookinetes. Antibodies against P25 prevent the formation of oocysts in the mosquito and thereby block transmission of the parasite through an endemic population. Plasmodium vivax transmission-blocking vaccines based on Pv25 have undergone human trials and inhibit transmissio...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2006.09.035

    authors: Ramjanee S,Robertson JS,Franke-Fayard B,Sinha R,Waters AP,Janse CJ,Wu Y,Blagborough AM,Saul A,Sinden RE

    更新日期:2007-01-15 00:00:00

  • Midwife attitudes: an important determinant of maternal postpartum pertussis booster vaccination.

    abstract:BACKGROUND:The study was designed to determine the feasibility of implementing routine dTpa vaccination in the maternity ward to new mothers and to assess midwives' attitudes toward pertussis booster vaccination, their perceived susceptibility and severity of pertussis in their patients' communities, the perceived barr...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2011.05.049

    authors: Robbins SC,Leask J,Hayles EH,Sinn JK

    更新日期:2011-08-05 00:00:00

  • Induction of pulmonary mucosal immune responses with a protein vaccine targeted to the DEC-205/CD205 receptor.

    abstract::It is of great interest to develop a pneumonic plague vaccine that would induce combined humoral and cellular immunity in the lung. Here we investigate a novel approach based on targeting of dendritic cells using the DEC-205/CD205 receptor (DEC) via the intranasal route as way to improve mucosal cellular immunity to t...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2012.08.051

    authors: Do Y,Didierlaurent AM,Ryu S,Koh H,Park CG,Park S,Perlin DS,Powell BS,Steinman RM

    更新日期:2012-10-05 00:00:00

  • Immune responses to intradermal and intramuscular inactivated influenza vaccine among older age group.

    abstract:BACKGROUD:Influenza viruses cause substantial morbidity, especially in older age groups. Thus, they are amongst high priority groups for routine vaccination. However, vaccine-induced immune responses and effectiveness were reported as relatively low. This study aims to systemically compare the immune responses elicited...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.vaccine.2017.10.106

    authors: Boonnak K,Dhitavat J,Thantamnu N,Kosoltanapiwat N,Auayporn M,Jiang L,Puthavathana P,Pitisuttithum P

    更新日期:2017-12-19 00:00:00

  • Decreasing invasive pneumococcal disease in the elderly: a state-level analysis.

    abstract::Evidence has accumulated supporting the relationship between the use of 7-valent pneumococcal conjugate vaccine (PCV7) in children and a decline in invasive pneumococcal disease (IPD) in the elderly. We conducted a state-level analysis of vaccination coverage rates among children 19-35 months of age and IPD hospitaliz...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2006.04.055

    authors: McBean AM,Jung K,Hebert PL

    更新日期:2006-07-07 00:00:00

  • Influenza virus antigens conjugated with a synthetic polyelectrolyte: a novel model of vaccines.

    abstract::Haemagglutinin (HA), a mixture of haemagglutinin and neuraminidase (HA + NA), and matrix (M) protein were isolated from the influenza A virus and covalently coupled to a synthetic polyelectrolyte (P). A single injection into mice of the resultant conjugates (virogates) brought about efficient stimulation of the primar...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(85)90130-6

    authors: Petrov RV,Khaitov RM,Zhdanov VM,Sinyakov MS,Norimov ASh,Nekrasov AV,Podchernyaeva RYa,Kharitonenkov IG,Shchipanova MV

    更新日期:1985-12-01 00:00:00

  • Mumps disease in Beijing in the era of two-dose vaccination policy, 2005-2016.

    abstract:BACKGROUND:Since the introduction of mumps-containing vaccines (MuCV) in 1995 in Beijing, two-dose MuCV vaccination policy has been used, with the 1st and 2nd doses given at 18 months and 6 years of age, respectively. METHODS:Mumps epidemiology during 2005-2016 was described using surveillance data. Vaccine effectiven...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2018.03.074

    authors: Ma R,Lu L,Zhou T,Pan J,Chen M,Pang X

    更新日期:2018-05-03 00:00:00

  • Designing and engineering of DNA-vaccine construction encoding multiple CTL-epitopes of major HIV-1 antigens.

    abstract::A synthetic T cell immunogen (TCI) has been designed as a candidate DNA-based vaccine against Human immunodeficiency virus (HIV)-1 using cytotoxic T lymphocytes (CD8(+) CTL) and T-helper lymphocytes (CD4(+) Th) epitopes retrieved from the Los Alamos HIV Molecular Immunology Database. The protein 392 amino acids in len...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2003.09.048

    authors: Bazhan SI,Belavin PA,Seregin SV,Danilyuk NK,Babkina IN,Karpenko LI,Nekrasova NA,Lebedev LR,Ignatyev GM,Agafonov AP,Poryvaeva VA,Aborneva IV,Ilyichev AA

    更新日期:2004-04-16 00:00:00

  • Expression of Cathepsin S in BCG converts it into a pro-apoptotic and highly immunogenic strain.

    abstract:BACKGROUND:BCG vaccine, introduced almost 100years ago, is the only option to prevent TB disease. It effectively protects newborns from meningeal TB but fails to prevent adult pulmonary TB. TB kills 1.3million people annually in areas where BCG vaccination is widely practiced. Thus, more effective TB vaccines are urgen...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2017.02.065

    authors: Lau A,Singh V,Soualhine H,Hmama Z

    更新日期:2017-04-11 00:00:00

  • Vaccines and the regulatory arm of the immune system. An overview from the Trypanosoma cruzi infection model.

    abstract::The knowledge that the immune system is composed of a regulatory/suppressor arm added a new point of view to better understand the nature of several pathologies including cancer, transplants, infections and autoimmune diseases. The striking discoveries concerning molecules and cells involved in this kind of regulation...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2019.05.015

    authors: Cabrera G,Marcipar I

    更新日期:2019-06-19 00:00:00

  • A novel therapeutic fusion protein vaccine by two different families of heat shock proteins linked with HPV16 E7 generates potent antitumor immunity and antiangiogenesis.

    abstract::Human papillomaviruses (HPV), particularly HPV16, is considered a necessary cause of cervical and oral cancer. Thus, the development of a therapeutic vaccine against HPV is important for the control of cervical cancer. However, therapeutic vaccination has been limited by inadequate antigen-specific immune responses. H...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2007.12.034

    authors: Liu B,Ye D,Song X,Zhao X,Yi L,Song J,Zhang Z,Zhao Q

    更新日期:2008-03-04 00:00:00

  • Precise answers to the wrong question: prospective clinical trials and the meta-analyses of pneumococcal vaccine in elderly and high-risk adults.

    abstract::Ten prospective clinical trials conducted in elderly and high-risk adults have failed to show that pneumococcal vaccine prevents pneumococcal bacteraemia and all pneumonia. Several of these trials focused on unrepresentative populations and most had serious methodological problems. Few adequately considered sample siz...

    journal_title:Vaccine

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.vaccine.2003.09.027

    authors: Fedson DS,Liss C

    更新日期:2004-02-25 00:00:00

  • Assessing potential introduction of universal or targeted hepatitis A vaccination in the Netherlands.

    abstract::In many industrialized countries, hepatitis A incidence rates have declined steadily in the past decades. Since future cohorts of non-vaccinated elderly will lack protection against disease and the burden of hepatitis A is higher with increasing age, this could be an argument in favour of taking preventive measures su...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2012.06.014

    authors: Suijkerbuijk AW,Lugnér AK,van Pelt W,Wallinga J,Verhoef LP,de Melker HE,de Wit GA

    更新日期:2012-07-27 00:00:00

  • Carrier-dependent specificity of antibodies to a conserved peptide determinant of gp120.

    abstract::Amino acid residues 421-436 constitute a comparatively conserved determinant of gp120 that participates in the binding of host cell CD4 receptors by HIV-1. We compared the immunogenicity of synthetic Cys-gp120 (421-436) conjugated to KLH via the N terminal Cys residue (KLH-I) and gp120 (421-436) extended at its N term...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(02)00504-2

    authors: Karle S,Nishiyama Y,Taguchi H,Zhou YX,Luo J,Planque S,Hanson C,Paul S

    更新日期:2003-03-07 00:00:00

  • Intranasal immunization with recombinant gD2 reduces disease severity and mortality following genital challenge with herpes simplex virus type 2 in guinea pigs.

    abstract::The ability of a genetically detoxified mutant of heat labile enterotoxin (LTK63) to act as a mucosal adjuvant following intranasal immunization with recombinant gD2 has previously been reported in mice [Ugozzoli M, O'Hagan DT, Ott GS. Intranasal immunization of mice with herpes simplex virus type 2 recombinant gD2: t...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(99)00009-2

    authors: O'Hagan D,Goldbeck C,Ugozzoli M,Ott G,Burke RL

    更新日期:1999-05-04 00:00:00

  • Feasibility of a pilot intervention to reduce pain and syncope during adolescent vaccination.

    abstract:PURPOSE:Vaccines recommended for adolescents are considered safe and effective, however administration may occasionally result in acute pain at the injection site or syncope (fainting). These adverse effects pose a risk to patient safety and are potential barriers to adherence to future vaccinations. We assessed a nove...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2018.05.070

    authors: Henninger ML,Kuntz JL,Firemark AJ,Varga AM,Bok K,Naleway AL

    更新日期:2018-06-22 00:00:00

  • Monitoring the process of measles elimination by serosurveillance data: The Apulian 2012 study.

    abstract::In 2003 Italy adopted the National Plan for Measles and Congenital Rubella Elimination, but some outbreaks of measles are still occurring, as the target coverage rate (≥ 95%) for new-borns has currently not been achieved. In order to support the monitoring of the measles elimination programme, the authors carried out ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.03.011

    authors: Tafuri S,Gallone MS,Gallone MF,Pappagallo MT,Larocca A,Germinario C

    更新日期:2016-04-19 00:00:00

  • Strengthening of causality assessment of adverse events following immunization in the WHO South East Asia and Western Pacific regions: Lessons from the 2014 SEAR inter-country workshop.

    abstract:BACKGROUND:Poorly managed AEFI undermine immunization programs. Improved surveillance in SEAR countries means more AEFIs but management varies. SEAR brought countries together to share AEFI experiences, and learn more about causality assessment. METHODS:Three day 10 country workshop (9 SEAR; 1 WPR). Participants outli...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2015.01.033

    authors: MacDonald NE,Guichard S,Amarasinghe A,Balakrishnan MR,2014 Inter-country SEAR Workshop Participants.

    更新日期:2015-11-27 00:00:00

  • Correlation of antibody titres induced by vaccination with protection in mouse typhoid.

    abstract::The ELISA method was used to titrate the humoral immune response in vaccinated mice. When mice were given two doses of a heat-killed salmonella vaccine 6 days apart, there was a steady but low-level increase of antibody synthesis. In contrast, if a booster vaccination was administered 21 days after the primary inocula...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(93)90256-w

    authors: Xu HR,Hsu HS,Moncure CW,King RA

    更新日期:1993-01-01 00:00:00

  • Safety and immunogenicity of a new formulation of an inactivated hepatitis A vaccine.

    abstract::The safety and immunogenicity of a new formulation of the inactivated hepatitis A vaccine, Avaxim, was evaluated in 189 children, aged 18 months to 15 years in a monocentric, open trial. Two vaccinations were given six months apart. Enrollment was balanced within three age groups: 18 months to 3 years, 4-8 years and 9...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0264-410x(98)00461-7

    authors: Dagan R,Greenberg D,Goldenbertg-Gehtman P,Vidor E,Briantais P,Pinsk V,Athias O,Dumas R

    更新日期:1999-04-09 00:00:00

  • Evaluation of immunization injection safety in China, 2010: achievements, future sustainability.

    abstract:OBJECTIVE:The study objectives were to evaluate injection practices in China in the post GAVI project era and provide guidance for policy makers to update national standards for injection practices and further improve vaccination services. METHODS:We conducted a national stratified, cross-sectional survey in October 2...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2012.11.057

    authors: Wu Z,Cui F,Chen Y,Miao N,Gong X,Luo H,Wang F,Zheng H,Kane M,Hadler SC,Hutin YJ,Liang X,Yang W

    更新日期:2013-12-27 00:00:00

  • Barriers to human papillomavirus vaccine acceptability in Israel.

    abstract::Barriers to human papillomavirus (HPV) vaccine acceptability in Israel include Israel's relatively low incidence of cervical cancer; the religiously-based 80% circumcision rate in Israel, which is regarded as contributing to the lower incidence of HPV infection in the country; the fact that HPV vaccine provides immuni...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2013.06.107

    authors: Fisher WA,Laniado H,Shoval H,Hakim M,Bornstein J

    更新日期:2013-11-22 00:00:00