Correlation of antibody titres induced by vaccination with protection in mouse typhoid.

abstract：:In March 2010, Brazil introduced the 10-valent pneumococcal conjugate vaccine (PCV10) in the routine infant immunization program using a 4-dose schedule and catch-up for children <23months. We investigated PCV10 effect on nasopharyngeal carriage with vaccine-type Streptococcus pneumoniae (Spn) and non-typeable Haemoph...

journal_title：Vaccine

authors： Brandileone MC,Zanella RC,Almeida SCG,Brandao AP,Ribeiro AF,Carvalhanas TMP,Sato H,Andrade AL,Verani JR,Pneumococcal Carriage Study Group.

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:Dengue diagnosis confirmation and surveillance are widely based on serological assays to detect anti-dengue IgM or IgG antibodies since such tests are affordable/user-friendly. The World Health Organization identified serological based diagnosis as a potential tool to define probable dengue cases in the cont...

journal_title：Vaccine

authors： Plennevaux E,Sabchareon A,Limkittikul K,Chanthavanich P,Sirivichayakul C,Moureau A,Boaz M,Wartel TA,Saville M,Bouckenooghe A

更新日期：2016-05-23 00:00:00

abstract：:Prior to routine immunisation, Haemophilus influenzae serotype b (Hib) was a major cause of serious bacterial infections, particularly in young children. In the United Kingdom, introduction of the Hib conjugate vaccine into the national childhood immunisation schedule has led to a sustained decline in invasive Hib dis...

journal_title：Vaccine

authors： Townsend K,Ladhani SN,Findlow H,Borrow R

更新日期：2014-09-29 00:00:00

abstract：INTRODUCTION:It is important to quickly identify parent beliefs, intentions, and behaviors toward childhood vaccination, especially parents of children 19 to 35 months. This paper describes parental immunization beliefs, intentions, and behaviors; assesses the relationships between beliefs and intentions regarding chil...

journal_title：Vaccine

authors： Boyle J,Berman L,Nowak GJ,Iachan R,Middleton D,Deng Y

更新日期：2020-02-28 00:00:00

abstract：:Classical swine fever virus (CSFV) causes significant losses in pig industry in many countries in Asia and Europe. The E2 glycoprotein of CSFV is the main target for neutralizing antibodies. Recently, the replicon of alphaviruses, such as Semliki Forest virus (SFV), has been developed as replicative expression vectors...

journal_title：Vaccine

authors： Li N,Qiu HJ,Zhao JJ,Li Y,Wang MJ,Lu BW,Han CG,Hou Q,Wang ZH,Gao H,Peng WP,Li GX,Zhu QH,Tong GZ

更新日期：2007-04-12 00:00:00

abstract：:In the present paper, an in vitro model was established in which the interaction between influenza virus-specific CD8+ T cells and human airway epithelial cells can be studied. To this end, the human lung epithelial cell line A549 was transduced with the HLA-A*0201 gene. This MHC class I allele is involved in the pres...

journal_title：Vaccine

authors： Rimmelzwaan GF,Boon AC,Geelhoed-Mieras MM,Voeten JT,Fouchier RA,Osterhaus AD

更新日期：2004-07-29 00:00:00

abstract：:Vaccination of poultry against coccidiosis caused by the Eimeria species is almost entirely based upon varied formulations of live parasites. The recent development of a series of protocols that support genetic complementation by transfection in Eimeria now provides an opportunity to utilise live anticoccidial vaccine...

journal_title：Vaccine

authors： Clark JD,Oakes RD,Redhead K,Crouch CF,Francis MJ,Tomley FM,Blake DP

更新日期：2012-03-30 00:00:00

abstract：:This randomized, double-blind trial conducted in the US and Canada was conducted to compare the safety and immunogenicity of two dosages of live attenuated oral monovalent G1 human rotavirus (HRV) vaccine administered orally at a 2-month interval concomitantly with routine childhood vaccines to healthy infants 5-15 we...

journal_title：Vaccine

authors： Dennehy PH,North American Human Rotavirus Vaccine Study Group.

更新日期：2006-05-01 00:00:00

abstract：:M2 is the third integral membrane protein of influenza A. M2e, the extracellular, 23 amino acid residues of M2, has been remarkably conserved in all human influenza A strains. This prompted us to evaluate the use of M2e as a potential broad-spectrum immunogen in a mouse model for influenza infection. Genetic fusion of...

journal_title：Vaccine

authors： De Filette M,Fiers W,Martens W,Birkett A,Ramne A,Löwenadler B,Lycke N,Jou WM,Saelens X

更新日期：2006-11-10 00:00:00

abstract：:Mumps virus is still circulating and annual mumps outbreaks occur with fluctuating magnitudes in Japan. Aseptic meningitis has been reported after vaccination and it would be of importance to determine whether this was related to the vaccination. The objective of this study was to develop a sensitive, specific and rap...

journal_title：Vaccine

authors： Yoshida N,Fujino M,Ota Y,Notomi T,Nakayama T

更新日期：2007-01-26 00:00:00

abstract：:To determine the potential for biodegradable alginate microspheres to be used as a delivery vehicle for DNA based vaccines, we constructed a plasmid, pMNe-gal-SV40, containing the bacterial beta-galactosidase (LacZ) gene under the control of the murine cytomegalovirus (MCMV) immediate-early promoter and the simian vir...

journal_title：Vaccine

authors： Mittal SK,Aggarwal N,Sailaja G,van Olphen A,HogenEsch H,North A,Hays J,Moffatt S

更新日期：2000-09-15 00:00:00

abstract：BACKGROUND:Patients with inflammatory rheumatic diseases are at higher risk for influenza and current guidelines recommend vaccination for this group of patients. The aim of this study was to evaluate the vaccination coverage and predictors for influenza vaccination among patients with inflammatory rheumatic diseases. ...

journal_title：Vaccine

authors： Harrison N,Poeppl W,Miksch M,Machold K,Kiener H,Aletaha D,Smolen JS,Forstner C,Burgmann H,Lagler H

更新日期：2018-08-06 00:00:00

abstract：:Although largely considered benign, Plasmodium vivax causes disease in nearly 75 million people each year and the available strategies are not sufficient to reduce the burden of disease, therefore pointing to vaccine development as a cost-effective control measure. In this study, the P. vivax merozoite surface protein...

journal_title：Vaccine

authors： Giraldo MA,Arevalo-Pinzon G,Rojas-Caraballo J,Mongui A,Rodriguez R,Patarroyo MA

更新日期：2009-12-10 00:00:00

abstract：:Streptococcus pneumoniae (pneumococcus) is responsible for significant morbidity and mortality in worldwide. After introduction of current pneumococcal vaccines, a marked decrease in the incidence of pneumococcal disease was observed. Unfortunately, serotype shifts in carriage and disease, including capsular switch an...

journal_title：Vaccine

authors： Kim EH,Choi SY,Kwon MK,Tran TD,Park SS,Lee KJ,Bae SM,Briles DE,Rhee DK

更新日期：2012-03-02 00:00:00

abstract：:The adenylate cyclase (CyaA) produced by Bordetella pertussis is able to deliver CD8+ and CD4+ T-cell epitopes genetically grafted within the catalytic domain of the molecule into antigen presenting cells in vivo. We develop now a new approach in which peptides containing CD8+ epitopes are chemically linked to CyaA. W...

journal_title：Vaccine

authors： Fayolle C,Bauche C,Ladant D,Leclerc C

更新日期：2004-12-16 00:00:00

abstract：:Heat killed spores of the Gram-positive bacterium Bacillus subtilis have been evaluated as a vaccine delivery system with mucosal adjuvant properties for influenza. Killed spores were able to bind H5N1 virions (NIBRG-14; clade 1) and, when intra-nasally administered to mice, resulting immune responses, both humoral an...

journal_title：Vaccine

authors： Song M,Hong HA,Huang JM,Colenutt C,Khang DD,Nguyen TV,Park SM,Shim BS,Song HH,Cheon IS,Jang JE,Choi JA,Choi YK,Stadler K,Cutting SM

更新日期：2012-05-09 00:00:00

abstract：BACKGROUND:This randomised, open label, phase I, immunotherapeutic study investigated the effects of interleukin (IL)-2, granulocyte-macrophage colony-stimulating factor (GM-CSF), recombinant human growth hormone (rhGH), and therapeutic immunisation (a Clade B DNA vaccine) on combination antiretroviral therapy (cART)-t...

journal_title：Vaccine

authors： Herasimtschuk A,Downey J,Nelson M,Moyle G,Mandalia S,Sikut R,Adojaan M,Stanescu I,Gotch F,Imami N

更新日期：2014-12-05 00:00:00

abstract：:Enterohemorrhagic Escherichia coli (EHEC) produces Stx1 and Stx2 causing severe diseases. Their B-subunits (StxBs) exhibit low immunogenicity and the anti-StxB antibodies neutralizing both Stxs has not been prepared yet. By intranasal vaccination with His-tagged-StxB (Stx1B-His or Stx2B-His) plus a mutant heat-labile ...

journal_title：Vaccine

authors： Tsuji T,Shimizu T,Sasaki K,Tsukamoto K,Arimitsu H,Ochi S,Shimizu T,Taniguchi K,Noda M,Neri P,Mori H

更新日期：2008-04-16 00:00:00

abstract：:Neutralizing antibody is associated with the prevention and clearance of influenza virus infection. Microneutralization (MN) and hemagglutination inhibition (HI) assays are currently used to evaluate neutralizing antibody responses against human and avian influenza viruses, including H5N1. The MN assay is somewhat lab...

journal_title：Vaccine

authors： Tsai C,Caillet C,Hu H,Zhou F,Ding H,Zhang G,Zhou B,Wang S,Lu S,Buchy P,Deubel V,Vogel FR,Zhou P

更新日期：2009-11-12 00:00:00

abstract：INTRODUCTION:The Global Vaccine Action Plan and the Regional Immunization Action Plan of the Americas call for countries to improve immunization data quality. Immunization information systems, particularly electronic immunization registries (EIRs), can help to facilitate program management and increase coverage. Howeve...

journal_title：Vaccine

authors： Trumbo SP,Contreras M,García AGF,Díaz FAE,Gómez M,Carrión V,Ruiz KJP,Aquije R,Danovaro-Holliday MC,Velandia-González M

更新日期：2018-11-29 00:00:00

abstract：:In this study, the impact of Th1-inducing cytokine gene co-delivery and antigen boosting on humoral and cellular responses induced by multiepitopic DNA immunization in mice have been investigated. Intramuscular injection of mixed DNA constructs encoding for HIV-1 Gag, Tat and Nef proteins, co-administered with the DNA...

journal_title：Vaccine

authors： Billaut-Mulot O,Idziorek T,Loyens M,Capron A,Bahr GM

更新日期：2001-04-06 00:00:00

abstract：BACKGROUND:Data on duration of protection against invasive meningococcal disease post-vaccination with the recombinant, 4-component, meningococcal serogroup B vaccine (4CMenB) are limited. We evaluated bactericidal activity persistence in adolescents/young adults up to 7.5 years post-primary vaccination with 4CMenB, an...

journal_title：Vaccine

authors： Nolan T,Santolaya ME,de Looze F,Marshall H,Richmond P,Henein S,Rheault P,Heaton K,Perrett KP,Garfield H,Gupta A,Ferguson M,D'Agostino D,Toneatto D,O'Ryan M

更新日期：2019-02-21 00:00:00

abstract：:Purified Vero cell culture rabies vaccine "Abhayrab" manufactured by Human Biologicals Institute, Ooty, India was subjected for immunogenicity studies. Pre-exposure study was undertaken on 60 healthy volunteers (Group I) with vaccination on days 0, 7 and 21. A group of 75 patients of category II (Group II), 67 of cate...

journal_title：Vaccine

authors： Sampath G,Reddy SV,Rao ML,Rao YU,Palaniappan C

更新日期：2005-01-04 00:00:00

abstract：INTRODUCTION:Ghana introduced monovalent rotavirus vaccine in April 2012. We sought to determine the long-term impact of routine rotavirus vaccination on rotavirus gastroenteritis hospitalizations in Ghana during the first 4 years following rotavirus vaccine introduction. METHODS:Active sentinel surveillance for acute...

journal_title：Vaccine

authors： Enweronu-Laryea CC,Armah G,Sagoe KW,Ansong D,Addo-Yobo E,Diamenu SK,Mwenda JM,Parashar UD,Tate JE

更新日期：2018-11-12 00:00:00

abstract：:The development of strategies to augment the immunogenicity of plasmid DNA vaccines is critical for improving their clinical utility. One such strategy involves the coadministration of plasmid cytokine adjuvants with DNA vaccines. Although a large number of plasmid cytokines have shown promise as adjuvants in preclini...

journal_title：Vaccine

authors： Barouch DH,Truitt DM,Letvin NL

更新日期：2004-08-13 00:00:00

abstract：:Human metapneumovirus (HMPV) expresses the major surface glycoproteins F and G. We evaluated the protective efficacy of immunization with G. We generated a recombinant form of G ectodomain (GDeltaTM) that was secreted from mammalian cells and purified by affinity chromatography. We tested the immunogenicity of GDeltaT...

journal_title：Vaccine

authors： Ryder AB,Tollefson SJ,Podsiad AB,Johnson JE,Williams JV

更新日期：2010-06-07 00:00:00

abstract：:Shigellosis, a major cause of diarrhea worldwide, exhibits high morbidity and mortality in children. Specificity of Shigella immunity is determined by the structure of the main protective O-antigen polysaccharide component incorporated into the lipopolysaccharide (LPS) molecule. Endotoxicity, however, precludes LPS cl...

journal_title：Vaccine

authors： Ledov VA,Golovina ME,Markina AA,Knirel YA,L'vov VL,Kovalchuk AL,Aparin PG

更新日期：2019-02-14 00:00:00

abstract：BACKGROUND:The compliance with influenza vaccination among health-care workers (HCWs) is known to be low. A multi-nationality survey to explore the reasons for such poor compliance has not been studied in depth. MATERIALS AND METHODS:An epidemiologic survey to evaluate the compliance rates with influenza vaccination a...

journal_title：Vaccine

authors： Al-Tawfiq JA,Antony A,Abed MS

更新日期：2009-09-04 00:00:00

abstract：:In the present study, we have produced recombinant paraflagellar rod proteins (PFR) and report their use for successful vaccination of mice against Trypanosoma cruzi. This protection is associated with a highly polarized type 1 cytokine production profile. Additionally, we have analyzed the gene sequence encoding PFR-...

journal_title：Vaccine

authors： Luhrs KA,Fouts DL,Manning JE

更新日期：2003-06-20 00:00:00

abstract：:We produced a Vero cell-derived inactivated Japanese encephalitis vaccine using a serum-free medium, as a substitute for the conventional mouse brain-derived Japanese encephalitis vaccine. The immunogenicity of this cell-derived vaccine was higher than that of the conventional mouse brain-derived vaccine. The results ...

journal_title：Vaccine

authors： Toriniwa H,Komiya T

更新日期：2011-02-24 00:00:00