Abstract：
:Humoral immunity against tick-borne encephalitis virus (TBEV) in patients with a well-documented history of naturally acquired tick-borne encephalitis (TBE) was compared with immunity resulting from vaccination in a carefully controlled immunization programme. The vaccination study was performed with a highly purified, inactivated virus particle vaccine and the immune response was followed by tracing the course of IgG antibody formation in an enzyme-linked immunosorbent assay and a neutralization assay. It was shown that this TBE vaccine induced a strong immune response. TBE IgG antibody titres measured after three vaccinations were of the same order of magnitude as those determined in patients recovered from manifest TBE.
journal_name
Vaccinejournal_title
Vaccineauthors
Klockmann U,Bock HL,Kwasny H,Praus M,Cihlová V,Tomková E,Krivanec Kdoi
10.1016/0264-410x(91)90315-wsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
42-6issue
1eissn
0264-410Xissn
1873-2518pii
0264-410X(91)90315-Wjournal_volume
9pub_type
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