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Alteration in L-type pyruvate kinase gene expression is not associated with the LF-B1 mRNA level.

Abstract：

:The relation of expression of the LF-B1 gene with the L-type pyruvate kinase (L-PK) mRNA level in rat liver and hepatoma cells was investigated. The L-PK mRNA level in rat liver changed after partial hepatectomy, during development and on intake of a high carbohydrate diet, while the level of LF-B1 mRNA remained unchanged or altered reciprocally. Dedifferentiated AH-130 cells, which did not express L-PK mRNA, expressed LF-B1 mRNA. These results suggest that transcription of the pyruvate kinase L gene is not simply regulated by the level of LF-B1 mRNA.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Imai E,Noguchi T,Takenaka M,Yamada K,Matsuda T,Monaci P,Nicosia A,Tanaka T

doi

10.1016/0006-291x(91)90393-l

subject

Has Abstract

pub_date

1991-05-15 00:00:00

pages

1074-8

issue

3

eissn

0006-291X

issn

1090-2104

pii

0006-291X(91)90393-L

journal_volume

176

pub_type

杂志文章

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