mRNA levels of enzymes and receptors implicated in arachidonic acid metabolism in gliomas.

abstract：OBJECTIVE:Effects of metamizol and magnesium sulfate on erythrocyte glucose 6-phosphate dehydrogenase enzyme activity were investigated in in vitro and in vivo conditions. METHODS:For in vitro studies, glucose 6-phosphate dehydrogenase was purified from human erythrocyte and rats were used for in vivo studies. Enzyme ...

journal_title：Clinical biochemistry

authors： Ciftçi M,Ozmen I,Büyükokuroğlu ME,Pençe S,Küfrevioğlu OI

更新日期：2001-06-01 00:00:00

abstract：:We compared results of urine drug analysis with clinical data and history to test the usefulness of peripartum drug screening and to establish guidelines for optimal testing. Urine from 28 mothers and 52 babies was analysed. Drugs not suspected by history were found in 10 mothers and six babies. Results assisted in th...

journal_title：Clinical biochemistry

authors： Halstead AC,Godolphin W,Lockitch G,Segal S

更新日期：1988-01-01 00:00:00

abstract：AIM:Medical laboratories are the key partners in patient safety. Laboratory results influence 70% of medical diagnoses. Quality of laboratory service is the major factor which directly affects the quality of health care. The clinical laboratory as a whole has to provide the best patient care promoting excellence. METH...

journal_title：Clinical biochemistry

authors： Guzel O,Guner EI

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:Breast cancer is the most common malignancy among Egyptian women. The aim of this study is to evaluate the role of both telomerase and TPS estimation in assessment of breast cancer. METHODS:The study included 40 patients with breast cancer, and 20 patients with benign breast diseases. Telomerase activity in...

journal_title：Clinical biochemistry

authors： Kassim SK,Fawzy H,El Rassad MM,Khalil FK,Khalifa A

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The gold standard test for the diagnosis of urinary tract infection is bacterial culture. However, urine cultures are labor intensive and costly. Furthermore, since results take 1-2 days many patients are treated presumptively prior to culture results being known. METHODS:We evaluated the Sysmex UF-1000i fo...

journal_title：Clinical biochemistry

authors： Giesen CD,Greeno AM,Thompson KA,Patel R,Jenkins SM,Lieske JC

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:The relationship between the severity of atherosclerotic coronary artery disease (CAD) and circulating levels of salusin-α, salusin-β and heregulin-β1 has been investigated. In addition, the relationship with these peptides and high sensitive C-reactive protein (hsCRP) has been investigated. METHODS:The stud...

journal_title：Clinical biochemistry

authors： Arkan A,Atukeren P,Ikitimur B,Simsek G,Koksal S,Gelisgen R,Ongen Z,Uzun H

更新日期：2021-01-01 00:00:00

abstract：:Cytosolic proteins that specifically bind cyclosporine A and FK-506 were isolated and purified from the JURKAT human T-helper cell line. These binding proteins were purified by affinity, molecular weight exclusion and weak cation exchange column chromatography. Radiolabeled cyclosporine A specifically bound to a appro...

journal_title：Clinical biochemistry

authors： Palaszynski EW,Donnelly JG,Soldin SJ

更新日期：1991-02-01 00:00:00

abstract：PURPOSE:Dermatan sulfate (DS) plays a number of roles in a wide range of biological activities such as cell signaling and tissue morphogenesis through interactions with various extracellular matrix proteins including collagen. Mutations in the carbohydrate sulfotransferase 14 gene (CHST14) encoding CHST14/dermatan 4-O-...

journal_title：Clinical biochemistry

authors： Mizumoto S,Kosho T,Hatamochi A,Honda T,Yamaguchi T,Okamoto N,Miyake N,Yamada S,Sugahara K

更新日期：2017-08-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Clinical biochemistry

authors： Delvin EE

更新日期：2006-04-27 00:00:00

abstract：:This review discusses the question: which steps are essential or need to be optimized so that maternal plasma RNA sequencing for pre-eclampsia and related syndromes will become as specific and sensitive as maternal plasma DNA sequencing for trisomy? ...

journal_title：Clinical biochemistry

authors： Oudejans CB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Vitamin B12 insufficiency/deficiency is common in mixed patient populations. However there is no single marker which can reliably diagnose B12 insufficiency/deficiency. Elevated concentrations of methylmalonic acid (MMA) are considered the most representative marker of metabolic vitamin B12 insufficiency, bu...

journal_title：Clinical biochemistry

authors： Sobczyńska-Malefora A,Gorska R,Pelisser M,Ruwona P,Witchlow B,Harrington DJ

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Mycophenolic acid requires routine therapeutic drug monitoring. We evaluated the suitability of a new PETINIA (particle enhanced turbidimetric inhibition immunoassay) assay on the Dimension EXL analyzer for monitoring of mycophenolic acid by comparing values obtained by this assay with a HPLC-UV method. DESI...

journal_title：Clinical biochemistry

authors： Dasgupta A,Tso G,Chow L

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:The non-invasive differentiation of ischemic and non-ischemic acute heart failure (AHF) not resulting from acute myocardial infarction is difficult and has therapeutic and prognostic implications. The aim of this study was to assess whether plasma B-type natriuretic peptide (BNP) can identify ischemic etiolo...

journal_title：Clinical biochemistry

authors： Kim SE,Park S,Kim JK,Kim SG,Kim HJ,Song YR

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:To develop a tandem mass spectrometry (MS/MS) method for plasma free and total carnitine, incorporating acid hydrolysis for total carnitine measurement, for improved accuracy and sample throughput. DESIGN AND METHODS:Limit of detection (LOD), limit of quantitation (LOQ), linearity, accuracy, precision coeff...

journal_title：Clinical biochemistry

authors： Johnson DW

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:It has recently been suggested that when adjusting doses of cyclosporine (CsA), determining its concentration in blood samples taken 2 h postdose (C(2)) is more clinically beneficial than using the predose concentration (C(0)). We determined C(0) and C(2) concentrations of CsA and their metabolites in sample...

journal_title：Clinical biochemistry

authors： Fernández-Marmiesse A,Hermida J,Tutor JC

更新日期：2000-07-01 00:00:00

abstract：:We describe a simple direct extraction method for the gas-liquid chromatography determination of serum valproic acid. The working range for the assay is 2-180 mg/L and our within-run precision was 5.8 and 4.3% at the 40 and 90 mg/L concentrations respectively. Hemolyzed and lipemic sera as well as samples from patient...

journal_title：Clinical biochemistry

authors： Leroux M,Budnik D,Hall K,Irvine-Meek J,Otten N,Seshia S

更新日期：1981-04-01 00:00:00

abstract：OBJECTIVES:An increase in oxidative stress may contribute to the development of oxidative protein damage in the aging rat skeletal muscle. Our aim was to reveal protein carbonyl (PCO), advanced oxidation protein products (AOPP), a novel marker of oxidative stress, and protein thiol (P-SH) levels as markers of protein o...

journal_title：Clinical biochemistry

authors： Cakatay U,Telci A,Kayali R,Tekeli F,Akçay T,Sivas A

更新日期：2003-02-01 00:00:00

abstract：:A method is described for xylose determination on the Ciba-Corning 550 Express that utilizes the slower enzymatic action of glucose dehydrogenase (GDH) on D-xylose, after prior removal of glucose. Glucose oxidase is added to serum or urine and incubated for 120 min at 37 degrees C. After incubation, a perchloric acid ...

journal_title：Clinical biochemistry

authors： Mori L

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Vitamin D (25-OHD) physiological functions have been expanded beyond traditional bone health, increasing the importance of its estimation in Laboratory Medicine, which renders validation of available methods mandatory. AIMS AND METHODS:We evaluated some preanalytical and analytical aspects of 25-OHD determi...

journal_title：Clinical biochemistry

authors： Bianchi S,Maffei S,Prontera C,Battaglia D,Vassalle C

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:Plasma retinol-binding protein (RBP) has been linked to insulin resistance and cardiovascular risk, yet little is know of its natural variation in plasma. We examined this in normal subjects and compared plasma levels and variability in lean subjects and subjects with the metabolic syndrome. METHODS:We esta...

journal_title：Clinical biochemistry

authors： Lewis JG,Shand BI,Frampton CM,Elder PA

更新日期：2007-07-01 00:00:00

abstract：:High-sensitivity cardiac troponin (hs-cTn) assays have been used clinically by thousands of physicians in many countries throughout the world since their clinical introduction seven years ago. In the early diagnosis of myocardial infarction (MI), beyond doubt the most important indication of hs-cTn assays, these simpl...

journal_title：Clinical biochemistry

authors： Twerenbold R,Boeddinghaus J,Nestelberger T,Wildi K,Rubini Gimenez M,Badertscher P,Mueller C

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:We determined the frequencies of apolipoprotein E (apo E) gene alleles and examined the association between apo E polymorphism and lipid parameters in a sample of the Tunisian population. DESIGN AND METHODS:Apo E polymorphism was investigated using PCR, and plasma lipid parameters were measured in 122 men a...

journal_title：Clinical biochemistry

authors： Jemaa R,Elasmi M,Naouali C,Feki M,Kallel A,Souissi M,Sanhaji H,Hadj Taïeb S,Souheil O,Kaabachi N

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to measure soluble receptor for advanced glycation end products (sRAGE) in plasma and synovial fluid of knee osteoarthritis (OA) patients and to determine the correlation between sRAGE levels and disease severity. DESIGN AND METHODS:Thirty-six OA patients and 15 healthy controls we...

journal_title：Clinical biochemistry

authors： Chayanupatkul M,Honsawek S

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:The relationship between glycated hemoglobin A1c (HbA1c) and average glucose has been described by the empirically derived estimated average glucose (eAG) equation in the A1c-Derived Average Glucose (ADAG) study, with extensive calibration efforts in four secondary reference HbA1c methods. It is not known if...

journal_title：Clinical biochemistry

authors： Loh TP,Sethi SK,Wong MS,Tai ES,Kao SL

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:The immune-inflammatory system has been implicated in the pathogenesis of diabetic nephropathy; however, many of the mechanisms involved remain unclear. Chitotriosidase enzyme is an active human chitinase and a major protein product of activated macrophages. Although playing an important role in innate and ac...

journal_title：Clinical biochemistry

authors： Elmonem MA,Amin HS,El-Essawy RA,Mehaney DA,Nabil M,Kamel LN,Farid IM

更新日期：2016-04-01 00:00:00

abstract：:Immunoglobulin levels are elevated in the acquired immune deficiency syndrome (AIDS) and one class, IgA, has been suggested as a marker of disease progression. IgA is composed of two subclasses, IgA1 and IgA2; circulating IgA1 is roughly 85% of the total in healthy individuals. We have attempted to determine if the su...

journal_title：Clinical biochemistry

authors： Cassulis P,Farhangfar R,DeBari VA

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVES:We have previously identified three minor immunophilins of molecular weights 37 kDa, 14 kDa, and 5-8 kDa capable of binding tacrolimus and sirolimus. DESIGN AND METHODS:When tested against pure preparations of five sirolimus metabolites, the 14 kDa protein had almost no cross-reactivity, the 37 kDa protein ...

journal_title：Clinical biochemistry

authors： Davis DL,Murthy JN,Gallant-Haidner H,Yatscoff RW,Soldin SJ

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Genetic variations of UDP-glucuronyltransferase 1A1 (UGT1A1) influence the concentration of serum bilirubin. We investigated the association of four common polymorphisms including UGT1A1-53(TA)(n), and common haplotypes of the UGT1A1 gene with bilirubin levels in 218 Caucasian volunteers. METHODS:Total bili...

journal_title：Clinical biochemistry

authors： Borucki K,Weikert C,Fisher E,Jakubiczka S,Luley C,Westphal S,Dierkes J

更新日期：2009-11-01 00:00:00

abstract：:Lipoprotein lipase (LPL) of adipose cells is present only in membrane compartments, mainly in the Golgi apparatus. LPL is a typical secretory protein which appears to be active as a homodimer. The process of LPL synthesis and maturation requires multiple steps. LPL is synthesized in the endoplasmic reticulum as an ina...

journal_title：Clinical biochemistry

authors： Ailhaud G

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:Prostate specific antigen (PSA) is a widely used and clinically valuable marker for prostate disease. In order to enable the development of new PSA assays and progress the understanding of the biology of PSA we have analyzed PSA in seminal plasma. DESIGN AND METHODS:PSA in seminal plasma from men attending ...

journal_title：Clinical biochemistry

authors： Végvári Á,Rezeli M,Sihlbom C,Häkkinen J,Carlsohn E,Malm J,Lilja H,Laurell T,Marko-Varga G

更新日期：2012-03-01 00:00:00