Immunomodulatory therapy of cutaneous T-cell lymphoma: a multimodality approach in advanced disease.

Abstract:

:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Jacqueline M. Junkins-Hopkins, MD, are provided after each discussion as a topic summary and are provided here as a special service to readers of the Journal of the American Academy of Dermatology.

journal_name

J Am Acad Dermatol

authors

Junkins-Hopkins JM

doi

10.1016/j.jaad.2009.09.024

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

1056-8

issue

6

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(09)01221-3

journal_volume

61

pub_type

杂志文章
  • Treatment of cicatricial (benign mucous membrane) pemphigoid with dapsone.

    abstract::Treatment of cicatricial pemphigoid is a problem because patients afflicted are elderly, the disease is chronic, systemic agents required for control are potentially toxic (particularly to older patients), and the disease is often in an advanced stage when the diagnosis is established and requires aggressive therapy f...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(82)70014-3

    authors: Rogers RS 3rd,Seehafer JR,Perry HO

    更新日期:1982-02-01 00:00:00

  • Angioinvasive fungal infections impacting the skin: Diagnosis, management, and complications.

    abstract::As discussed in the first article in this continuing medical education series, angioinvasive fungal infections pose a significant risk to immunocompromised and immunocompetent patients alike, with a potential for severe morbidity and high mortality. The first article in this series focused on the epidemiology and clin...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2018.04.058

    authors: Berger AP,Ford BA,Brown-Joel Z,Shields BE,Rosenbach M,Wanat KA

    更新日期:2019-04-01 00:00:00

  • Electrocardiography electrode and hand dermatitis from parachlorometaxylenol.

    abstract::Parachlorometaxylenol is used as a germicide in many topical products. To our knowledge, this is the first case of dermatitis from parachlorometaxylenol in electrocardiograph electrodes used with cardiac monitors. The patient also had hand eczema from a germicidal soap containing parachlorometaxylenol. In addition, ou...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(86)70175-8

    authors: Ranchoff RE,Steck WD,Taylor JS,Evey P

    更新日期:1986-08-01 00:00:00

  • CD30 (Ki-1)-positive large-cell cutaneous T-cell lymphoma with secondary xanthomatous changes after radiation therapy.

    abstract::A 72-year-old woman with a large mass on her forehead was found to have primary cutaneous CD30-positive large T-cell lymphoma and was treated with radiation therapy. Five weeks after the completion of radiation therapy, a large, yellow plaque developed on the forehead. Histopathologic examination showed numerous xanth...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2003.123

    authors: Chung HG,Chung YL,Kang JM,Yang WI,Suh CO,Hahn JS,Leea MG

    更新日期:2003-02-01 00:00:00

  • Hyperkeratosis lenticularis perstans (Flegel's disease). Case report and literature review.

    abstract::A case of Flegel's disease, or hyperkeratosis lenticularis perstans, is reported. This rare chronic disorder is characterized by asymptomatic hyperkeratotic papules, usually located on the lower extremities. Most reported cases have been from Europe. We report a case of hyperkeratosis lenticularis perstans from our in...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(87)80060-9

    authors: Pearson LH,Smith JG Jr,Chalker DK

    更新日期:1987-01-01 00:00:00

  • An unusual case of non-Langerhans cell histiocytosis.

    abstract::A 28-month-old boy had firm, red nodules for 4 months that were mostly localized to the face. The eruption was preceded by conjunctivitis, eyelid edema, and swelling of the root of the nose. He also had dyspnea, anisocoria with areflexia, swelling of the parotid glands, and hepatosplenomegaly. A bone marrow aspirate s...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(94)70042-7

    authors: Caputo R,Grimalt R,Ermacora E,Cavicchini S,Portaleone D

    更新日期:1994-02-01 00:00:00

  • In vivo percutaneous absorption of hydrocortisone in psoriatic patients and normal volunteers.

    abstract::Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(83)70072-1

    authors: Wester RC,Bucks DA,Maibach HI

    更新日期:1983-05-01 00:00:00

  • Use of topical antibiotics as prophylaxis in clean dermatologic procedures.

    abstract:BACKGROUND:Topical antibiotics are not indicated for routine postoperative care in clean dermatologic procedures, but may be widely used. OBJECTIVE:We sought to describe topical antibiotic use in clean dermatologic surgical procedures in the United States. METHODS:The 1993 to 2007 National Ambulatory Medical Care Sur...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2011.02.005

    authors: Levender MM,Davis SA,Kwatra SG,Williford PM,Feldman SR

    更新日期:2012-03-01 00:00:00

  • Prevalence of sunburn, sun protection, and indoor tanning behaviors among Americans: review from national surveys and case studies of 3 states.

    abstract:BACKGROUND:Exposure to ultraviolet radiation (from solar and nonsolar sources) is a risk factor for skin cancer. OBJECTIVE:We sought to summarize recent estimates on sunburns, sun-protection behaviors, and indoor tanning available from national and selected statewide behavioral surveys. METHODS:Estimates of the preva...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2011.05.033

    authors: Buller DB,Cokkinides V,Hall HI,Hartman AM,Saraiya M,Miller E,Paddock L,Glanz K

    更新日期:2011-11-01 00:00:00

  • Congenital melanocytic nevi in young children: Histopathologic features and clinical outcomes.

    abstract:BACKGROUND:Although only large congenital melanocytic nevi (CMN) are associated with a significantly high risk for malignant transformation, CMN of all sizes are prone to changes in clinical appearance in early childhood and thus are often biopsied or excised. While CMNs typically exhibit benign behavior, atypical hist...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2016.12.026

    authors: Simons EA,Huang JT,Schmidt B

    更新日期:2017-05-01 00:00:00

  • The PASE questionnaire: pilot-testing a psoriatic arthritis screening and evaluation tool.

    abstract:BACKGROUND:Complications associated with psoriatic arthritis (PsA) may be prevented with early diagnosis and initiation of therapy. Up to one third of psoriasis patients may have PsA. There is a need to screen psoriasis patients early for symptoms of PsA. OBJECTIVE:To develop and validate a patient self-administered t...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2007.04.001

    authors: Husni ME,Meyer KH,Cohen DS,Mody E,Qureshi AA

    更新日期:2007-10-01 00:00:00

  • A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis siné myositis): a missing link within the spectrum of the idiopathic inflammatory myopathies.

    abstract:OBJECTIVE:Classical dermatomyositis (CDM) patients display the hallmark cutaneous manifestations of dermatomyositis (DM), proximal muscle weakness, and laboratory evidence of myositis. The epidemiology and management of both adult-onset and juvenile-onset CDM has been well characterized. However, the clinical significa...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.10.041

    authors: Gerami P,Schope JM,McDonald L,Walling HW,Sontheimer RD

    更新日期:2006-04-01 00:00:00

  • T-cell clonality of peripheral blood lymphocytes in patients with lymphomatoid papulosis.

    abstract::Six patients with lymphomatoid papulosis demonstrated a clonal T-cell population in skin lesions by polymerase chain reaction methods. Two of these patients showed identical T-cell clones in their peripheral blood T cells as well. In one case, the clone persisted in the blood despite clearing of skin lesions with meth...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2005.01.014

    authors: Schultz JC,Granados S,Vonderheid EC,Hwang ST

    更新日期:2005-07-01 00:00:00

  • Medium-dose is more effective than low-dose ultraviolet A1 phototherapy for localized scleroderma as shown by 20-MHz ultrasound assessment.

    abstract:BACKGROUND:Recent studies suggest that ultraviolet (UV) A1 phototherapy is an effective treatment for localized scleroderma (LS); however, the optimum UVA1 dose remains to be determined. OBJECTIVE:We sought to compare the immediate and long-term efficacy of low- versus medium-dose UVA1 phototherapy for plaque-type LS....

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2008.12.013

    authors: Sator PG,Radakovic S,Schulmeister K,Hönigsmann H,Tanew A

    更新日期:2009-05-01 00:00:00

  • B-RAF and melanocytic neoplasia.

    abstract::High frequency of B-RAF gene mutations has recently been identified in benign melanocytic nevi and melanoma. This review focuses on clinical studies that evaluate the role of B-RAF in melanocytic neoplasia. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.04.013

    authors: Gill M,Celebi JT

    更新日期:2005-07-01 00:00:00

  • Mechanisms of action of topical therapies and the rationale for combination therapy.

    abstract::The advent of new topical agents such as topical calcineurin inhibitors, as well as the reformulations of older agents in new vehicles, has broadened the treatment approaches to psoriasis and atopic dermatitis. The clinician must now consider additional novel physiologic pathways and mechanisms of action as well as ex...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.04.027

    authors: Norris DA

    更新日期:2005-07-01 00:00:00

  • Transient myeloproliferative disorder with vesiculopustular eruption: Early smear is useful for quick diagnosis.

    abstract::We report a male infant with Down syndrome who had a transient myeloproliferative disorder associated with skin lesions. He was transferred to a neonatal intensive care unit because of low body weight, fetal edema, disseminated intravascular coagulation, and 10% blast cells in the peripheral blood. On postnatal day (P...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2008.09.029

    authors: Uhara H,Shiohara M,Baba A,Shiohara J,Saida T

    更新日期:2009-05-01 00:00:00

  • Basaloid squamous cell carcinoma of the skin.

    abstract:BACKGROUND:Basaloid squamous cell carcinoma (BSCC), an aggressive tumor of the aerodigestive tract, was described over 20 years ago, and its defining histologic parameters remain largely unchanged. While rare reports have noted cutaneous metastatic deposition, primary tumors have not been previously described. OBJECTI...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2010.02.051

    authors: Boyd AS,Stasko TS,Tang YW

    更新日期:2011-01-01 00:00:00

  • Elastin staining patterns in primary cicatricial alopecia.

    abstract:BACKGROUND:Most biopsy specimens of cicatricial (scarring) alopecia can be readily subclassified as lymphocytic versus neutrophilic, but specific diagnosis remains difficult, particularly when a late stage of the disease is sampled. OBJECTIVE:We sought to document patterns of scarring highlighted by elastic tissue sta...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2013.07.018

    authors: Fung MA,Sharon VR,Ratnarathorn M,Konia TH,Barr KL,Mirmirani P

    更新日期:2013-11-01 00:00:00

  • Patterns of distribution of giant congenital melanocytic nevi (GCMN): The 6B rule.

    abstract:BACKGROUND:Garment-related terms have been used to describe the pattern of distribution of giant congenital melanocytic nevi (GCMN). OBJECTIVE:We sought to describe patterns of distribution of GCMN and propose a classification scheme. METHODS:Photographic records of patients with GCMN from the Hospital Clinic of Barc...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2016.05.042

    authors: Martins da Silva VP,Marghoob A,Pigem R,Carrera C,Aguilera P,Puig-Butillé JA,Puig S,Malvehy J

    更新日期:2017-04-01 00:00:00

  • Psoriasis herpeticum: three cases of Kaposi's varicelliform eruption in psoriasis.

    abstract:BACKGROUND:Kaposi's varicelliform eruption (KVE), first described in 1887 by Moritz Kaposi, refers to a disseminated cutaneous infection with herpesvirus type 1 or 2, vaccinia virus, or coxsackievirus A16 in a patient with another underlying dermatosis. When herpesvirus type 1 or 2 is the pathogenic virus, the term "ec...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.01.140

    authors: Santmyire-Rosenberger BR,Nigra TP

    更新日期:2005-07-01 00:00:00

  • Cutaneous lesions of hemophagocytic syndrome in a patient with T-cell lymphoma and active Epstein-Barr infection.

    abstract::The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(91)70284-9

    authors: Smith KJ,Skelton HG 3rd,Giblin WL,James WD

    更新日期:1991-11-01 00:00:00

  • The pharmacology of methotrexate.

    abstract::Methotrexate is a useful antimetabolite for the treatment of both benign and malignant proliferative disorders. When the pharmacokinetics and potential toxicity of this drug are understood, treatment regimens can be tailored to the underlying kinetics of the target population. With the appropriate knowledge of the imp...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/0190-9622(91)70199-c

    authors: Olsen EA

    更新日期:1991-08-01 00:00:00

  • Reactive perforating collagenosis in a setting of double disaster: acquired immunodeficiency syndrome and end-stage renal disease.

    abstract::We report reactive perforating collagenosis in an intravenous heroin abuser with acquired immunodeficiency syndrome and end-stage renal disease. The literature on perforating disorders in patients with acquired immunodeficiency syndrome and the pathogenesis of reactive perforating collagenosis in this setting is revie...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(89)80037-4

    authors: Bank DE,Cohen PR,Kohn SR

    更新日期:1989-08-01 00:00:00

  • Heart disease in psoriasis.

    abstract::Psoriasis has been traditionally viewed as an inflammatory skin disorder of unknown origin. Recent advances in the immunopathogenesis and genetics of psoriasis have broadened our understanding of psoriasis. Psoriasis is now considered a systemic inflammatory condition analogous to other inflammatory immune disorders. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2007.02.007

    authors: Kremers HM,McEvoy MT,Dann FJ,Gabriel SE

    更新日期:2007-08-01 00:00:00

  • Lipoid proteinosis with pseudomembranous conjunctivitis.

    abstract::Lipoid proteinosis is a rare autosomal recessive condition characterized by a diffuse mucocutaneous infiltration with histopathologic deposits that are positive for periodic acid-Schiff reagent and a sudanophil substance. We present a 9-year-old boy with lipoid proteinosis. His parents are siblings. He had classical m...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(86)70045-5

    authors: Barthelemy H,Mauduit G,Kanitakis J,Cambazard F,Thivolet J

    更新日期:1986-02-01 00:00:00

  • Occurrence of Langerhans cells and expression of class II antigens on keratinocytes in malignant and benign epithelial tumors of the skin: an immunohistopathologic study with monoclonal antibodies.

    abstract::We used an avidin-biotin complex immunoperoxidase technique with various monoclonal antibodies to determine Langerhans cell densities, class II antigen expression on keratinocytes, and phenotypes of other infiltrating cells in several malignant and benign epithelial tumors of the skin. Our observations indicate (1) th...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(89)70125-0

    authors: Chen HD,Zhao YM,Sun G,Yang CY

    更新日期:1989-06-01 00:00:00

  • Mastocytosis and the mast cell.

    abstract::Mastocytosis is a disease in which the mast cell population is increased in various tissues. Although the mechanism for the increased density of mast cells is not understood, recent research into mast cell structure and function has improved our understanding of the symptomatology and prompted newer and better approac...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(82)70152-5

    authors: DiBacco RS,DeLeo VA

    更新日期:1982-12-01 00:00:00

  • Cutaneous lentiginosis with atrial myxomas.

    abstract::This report describes a 25-year-old white woman with lentigines, cutaneous myxomas, bilateral atrial myxomas, and cerebral artery aneurysms. We believe this case to be the fifth reported case of this unusual association in the medical literature, with the additional finding of a central nervous system aneurysm. In the...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(86)70188-6

    authors: Reed OM,Mellette JR Jr,Fitzpatrick JE

    更新日期:1986-08-01 00:00:00

  • Pityriasis rubra pilaris and HIV infection.

    abstract::Many cutaneous diseases have been reported in patients with human immunodeficiency virus infection. We report two patients with pityriasis rubra pilaris and human immunodeficiency virus infection. In one patient, the onset of pityriasis rubra pilaris preceded the discovery of human immunodeficiency virus infection. In...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(91)70106-c

    authors: Blauvelt A,Nahass GT,Pardo RJ,Kerdel FA

    更新日期:1991-05-01 00:00:00