An unusual case of non-Langerhans cell histiocytosis.

abstract：:In this randomized, double-blind, phase III trial, patients with psoriasis received etanercept for 24 weeks or placebo for 12 weeks followed by etanercept for 12 weeks. At week 12, improvement in Dermatology Life Quality Index was 47% to 61% with etanercept compared with 11% with placebo (P < .0001). Etanercept rapidl...

journal_title：Journal of the American Academy of Dermatology

authors： Feldman SR,Kimball AB,Krueger GG,Woolley JM,Lalla D,Jahreis A

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Isotretinoin is a very effective drug for treating severe recalcitrant nodular acne. A new micronized formulation of isotretinoin has been shown to be clinically equivalent to standard isotretinoin with improved bioavailability and minimal food effect. The safety profile of the micronized formulation has not...

journal_title：Journal of the American Academy of Dermatology

authors： Strauss JS,Leyden JJ,Lucky AW,Lookingbill DP,Drake LA,Hanifin JM,Lowe NJ,Jones TM,Stewart DM,Jarratt MT,Katz I,Pariser DM,Pariser RJ,Tschen E,Chalker DK,Rafal ES,Savin RP,Roth HL,Chang LK,Baginski DJ,Kempers S,M

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Vascular cell adhesion molecule-1 (VCAM-1) is an endothelial protein with adhesive properties for inflammatory cells including lymphocytes. Its role in skin disease and regulation in vivo are uncertain. OBJECTIVE:Our purpose was to determine expression of VCAM-1 in normal and inflamed skin and the effect on...

journal_title：Journal of the American Academy of Dermatology

authors： Groves RW,Ross EL,Barker JN,MacDonald DM

更新日期：1993-07-01 00:00:00

abstract：:We present the case of two patients with an unusual form of discoid lupus erythematosus that was confined almost exclusively to the palms and soles. In both patients this form of discoid lupus erythematosus did not respond to conventional therapies, which included topical steroids, intralesional steroids, prednisone, ...

journal_title：Journal of the American Academy of Dermatology

authors： Ashinoff R,Werth VP,Franks AG Jr

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Necrolytic migratory erythema (NME) is an uncommon inflammatory dermatosis with a distinct clinical and histologic appearance. NME is usually associated with glucagonoma. Only a few cases of NME in the absence of glucagonoma have been previously reported. OBJECTIVE:We sought to understand further the pathog...

journal_title：Journal of the American Academy of Dermatology

authors： Marinkovich MP,Botella R,Datloff J,Sangueza OP

更新日期：1995-04-01 00:00:00

abstract：CAPSULE SUMMARY:In this article, we try to use the syringes without the piston part to control the amount of saline fluid in dermabrasion surgery. It is very convenient to obtain materials and simple to operate in skin surgery. ...

journal_title：Journal of the American Academy of Dermatology

authors： Cao C,Li H,Shao Z

更新日期：2020-10-10 00:00:00

abstract：BACKGROUND:Indoor tanning may increase the risk of melanoma and other health problems. Frequent users of indoor tanning facilities may be at particularly high risk. OBJECTIVE:In study 1 our purpose was to assess the prevalence and nature of indoor tanning advertisements; in study 2 we aimed to assess tanning facility ...

journal_title：Journal of the American Academy of Dermatology

authors： Kwon HT,Mayer JA,Walker KK,Yu H,Lewis EC,Belch GE

更新日期：2002-05-01 00:00:00

abstract：:Sulfur is a time-honored therapeutic agent useful in a variety of dermatologic disorders. Its keratolytic action is due to formation of hydrogen sulfide through a reaction that depends upon direct interaction between sulfur particles and keratinocytes. The smaller the particle size, the greater the degree of such inte...

journal_title：Journal of the American Academy of Dermatology

authors： Lin AN,Reimer RJ,Carter DM

更新日期：1988-03-01 00:00:00

abstract：:Alendronate is a bisphosphonate compound used to treat diseases of pathologic bone resorption. Cutaneous reactions to this medication are rare. We report the case of a superficial gyrate erythema that occurred as a reaction to weekly alendronate therapy used in the treatment of postmenopausal osteoporosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Cohen JB,Wetherington W,Cockerell CJ

更新日期：2003-06-01 00:00:00

abstract：:We report a case of a 10-month-old male infant with GM1 type 1 gangliosidosis who also had hyperpigmented macules and patches. Light and electron microscopic findings correlated with previously published reports on findings in skin biopsy specimens of patients with lipid storage disorders. The hyperpigmented macules a...

journal_title：Journal of the American Academy of Dermatology

authors： Selsor LC,Lesher JL Jr

更新日期：1989-05-01 00:00:00

abstract：:Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

journal_title：Journal of the American Academy of Dermatology

authors： Elias PM

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Patients with pemphigus vulgaris (PV) are genetically linked to two alleles of the HLA subgroup, and circulating antibodies were found in first-degree relatives of these patients, thus showing genetic predisposition. OBJECTIVE:Our purpose was to determine the occurrence of circulating true PV-IgG in patient...

journal_title：Journal of the American Academy of Dermatology

authors： Brandsen R,Frusic-Zlotkin M,Lyubimov H,Yunes F,Michel B,Tamir A,Milner Y,Brenner S

更新日期：1997-01-01 00:00:00

abstract：:A new technic is described for more accurately checking the surgical margins of skin tumors removed by standard surgical excision. Vertical sections of surgical specimens represent check points of the margin only 7 microns thick. This means most of the surgical margin is not checked microscopically, allowing small tum...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz BC,Roenigk HH Jr

更新日期：1982-10-01 00:00:00

abstract：:This prospective study (1977-1980) of cosmetic adverse reactions by eleven dermatologists identified 487 cases of cosmetic-induced dermatitis. Approximately half of the cases were covert in nature. Eight percent were due to allergic contact dermatitis; the face, eye, and upper arm were the most involved sites. Skin ca...

journal_title：Journal of the American Academy of Dermatology

authors： Eiermann HJ,Larsen W,Maibach HI,Taylor JS

更新日期：1982-05-01 00:00:00

abstract：:Lupus pernio has been associated with sarcoidosis of the upper respiratory tract. The semantic differences in the use of the designation "lupus pernio" are such that American dermatologists may not consider patients with nasal rim papules of sarcoidosis to have lupus pernio. During a 12-month period, we referred each ...

journal_title：Journal of the American Academy of Dermatology

authors： Jorizzo JL,Koufman JA,Thompson JN,White WL,Shar GG,Schreiner DJ

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:The results of a recent study suggested that ultraviolet A1 radiation (UVA1R; 340-400 nm) phototherapy for atopic dermatitis works through induction of apoptosis in skin-infiltrating helper T cells, indicating the possibility that other helper T cell-mediated skin diseases may respond to UVA1R as well. OBJE...

journal_title：Journal of the American Academy of Dermatology

authors： Plettenberg H,Stege H,Megahed M,Ruzicka T,Hosokawa Y,Tsuji T,Morita A,Krutmann J

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:Cyclosporine is highly effective in the treatment of a multitude of dermatoses. Concern over its side effect profile has limited its use in dermatology. Adverse effects are, for the most part, dose dependent and related to duration of therapy. Using the recommended monitoring protocols results in a significa...

journal_title：Journal of the American Academy of Dermatology

authors： Ryan C,Amor KT,Menter A

更新日期：2010-12-01 00:00:00

abstract：:There is no topical antiacne medication that acts against all four of the major pathophysiologic features of acne: hyperkeratinization, sebum production, bacterial proliferation, and inflammation. Topical azelaic acid cream helps both to normalize keratinization and to reduce the proliferation of Propionibacterium acn...

journal_title：Journal of the American Academy of Dermatology

authors： Webster G

更新日期：2000-08-01 00:00:00

abstract：:A new, quantitative modification of the vasoconstrictor assay was used to measure bioavailability of generic topical corticosteroid products in two categories: betamethasone valerate 0.1% cream and triamcinolone 0.1% cream. Betamethasone valerate products could be separated into two distinct categories, and triamcinol...

journal_title：Journal of the American Academy of Dermatology

authors： Jackson DB,Thompson C,McCormack JR,Guin JD

更新日期：1989-05-01 00:00:00

abstract：:Myospherulosis is an uncommon subcutaneous disorder believed initially to be caused by an endosporulating fungus. Recently investigators have disproved an infectious cause and have shown that the disease represents an alteration in red blood cells, usually produced by petrolatum or lanolin, with an accompanying foreig...

journal_title：Journal of the American Academy of Dermatology

authors： Waldman JS,Barr RJ,Espinoza FP,Simmons GE

更新日期：1989-08-01 00:00:00

abstract：:A 72-year-old woman with a large mass on her forehead was found to have primary cutaneous CD30-positive large T-cell lymphoma and was treated with radiation therapy. Five weeks after the completion of radiation therapy, a large, yellow plaque developed on the forehead. Histopathologic examination showed numerous xanth...

journal_title：Journal of the American Academy of Dermatology

authors： Chung HG,Chung YL,Kang JM,Yang WI,Suh CO,Hahn JS,Leea MG

更新日期：2003-02-01 00:00:00

abstract：:Carcinoma erysipelatodes, also known as inflammatory metastatic carcinoma, is a type of cutaneous metastatic disease. We describe a 64-year-old woman with metastatic breast carcinoma who presented with a blistering erythematous eruption resembling erysipelas with formation of vesicles and bullae. She was found to have...

journal_title：Journal of the American Academy of Dermatology

authors： Meadows KP,Egan CA

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Ultraviolet B phototherapy is underused because of costs and inconvenience. Home phototherapy may alleviate these issues, but training is spotty, and many physicians are not comfortable prescribing home phototherapy. OBJECTIVE:The purpose of this review is to provide a practical guide for recognizing approp...

journal_title：Journal of the American Academy of Dermatology

authors： Anderson KL,Feldman SR

更新日期：2015-05-01 00:00:00

abstract：:Seborrheic dermatitis is generally treated with topical steroids, antifungals, or both. This pilot study was undertaken to examine the possibility of tacrolimus as a useful therapy for seborrheic dermatitis. In a single-center, open-label study, 18 consecutive patients with seborrheic dermatitis were treated with 0.1%...

journal_title：Journal of the American Academy of Dermatology

authors： Meshkinpour A,Sun J,Weinstein G

更新日期：2003-07-01 00:00:00

abstract：:Lupus erythematosus (LE) is a multisystem disease. Genetic predisposition, altered immunity, hormones, drugs, viruses, and ultraviolet light all may play a role in etiology. A wide range of cutaneous lesions occur, and variants such as subacute cutaneous LE, complement-deficient LE, and neonatal LE have recently been ...

journal_title：Journal of the American Academy of Dermatology

authors： Tuffanelli DL

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:The adult burden of atopic dermatitis (AD) is poorly characterized. OBJECTIVE:We sought to characterize AD burden in adults with moderate to severe disease from the patient's perspective. METHODS:Patient-reported outcomes collected at screening in a phase 2b clinical trial of dupilumab included pruritus nu...

journal_title：Journal of the American Academy of Dermatology

authors： Simpson EL,Bieber T,Eckert L,Wu R,Ardeleanu M,Graham NM,Pirozzi G,Mastey V

更新日期：2016-03-01 00:00:00

abstract：:Scleromyxedema is a rare cutaneous disease with occasional systemic involvement and characteristic poor response to treatment. A case of scleromyxedema associated with renal scleroderma and acute psychosis is presented, along with a review of treatment and associated internal disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kantor GR,Bergfeld WF,Katzin WE,Reynolds OD,Biscardi AP,Lobur DM,Box TA,Schreiber MJ Jr,Ratliff NB

更新日期：1986-05-01 00:00:00

abstract：:Incontinentia pigmenti is a rare genodermatosis of unknown etiology. A female infant with features typical of this disease was found to have basophils in early vesicular lesions. Mediators from these cells may be responsible for the accumulation of eosinophils in these lesions. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schmalstieg FC,Jorizzo JL,Tschen J,Subrt P

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Poor compliance with treatment advice in chronic conditions, such as psoriasis, represents a major challenge to health care professionals. Previous research suggests that the rate of noncompliance in chronic conditions may be as high as 40%. OBJECTIVE:This study was designed to examine self-reported complia...

journal_title：Journal of the American Academy of Dermatology

authors： Richards HL,Fortune DG,O'Sullivan TM,Main CJ,Griffiths CE

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Increasing incidence and mortality rates from cutaneous melanoma are a major public health concern. As part of a national effort to enhance early detection of melanoma/skin cancer, the American Academy of Dermatology (AAD) has sponsored an annual education and early detection program that couples provision o...

journal_title：Journal of the American Academy of Dermatology

authors： Koh HK,Norton LA,Geller AC,Sun T,Rigel DS,Miller DR,Sikes RG,Vigeland K,Bachenberg EU,Menon PA,Billon SF,Goldberg G,Scarborough DA,Ramsdell WM,Muscarella VA,Lew RA

更新日期：1996-06-01 00:00:00