Effect of pioglitazone on systemic inflammation is independent of metabolic control and cardiac autonomic function in patients with type 2 diabetes.

abstract：:Studies suggest that diabetes may specifically elevate the risk of sudden cardiac death in excess of other heart disease outcomes. In this study, we examined the association of type 2 diabetes with the incidence of sudden cardiac death when compared to the incidence of non-sudden cardiac death and non-fatal myocardial...

journal_title：Acta diabetologica

authors： Kucharska-Newton AM,Couper DJ,Pankow JS,Prineas RJ,Rea TD,Sotoodehnia N,Chakravarti A,Folsom AR,Siscovick DS,Rosamond WD

更新日期：2010-12-01 00:00:00

abstract：:Bacterial endotoxins have been associated with chronic inflammation and the development and progression of diabetic nephropathy. We hypothesized that subjects with high serum lipopolysaccharide activity also carry remains of bacterial DNA in their system. Serum-derived bacterial DNA clones were isolated and identified...

journal_title：Acta diabetologica

authors： Peräneva L,Fogarty CL,Pussinen PJ,Forsblom C,Groop PH,Lehto M

更新日期：2013-06-01 00:00:00

abstract：:Serum total bilirubin (TB) is a potent antioxidant and inversely associated with metabolic syndrome (MetS) in Asian populations. However, there has been no study which is aimed to investigate whether TB is a risk factor for MetS or not. We investigated cross-sectional and longitudinal associations between TB and MetS ...

journal_title：Acta diabetologica

authors： Oda E,Aizawa Y

更新日期：2013-06-01 00:00:00

abstract：AIM:To assess the association between alcohol consumption and/or cigarette smoking with other unhealthy behaviors and clinical cardiovascular risk factors in youth with type 1 diabetes. METHODS:Two hundred and twenty-eight youth with type 1 diabetes (age 13-19 years) were consecutively enrolled in three Regional Pedia...

journal_title：Acta diabetologica

authors： Valerio G,Mozzillo E,Zito E,De Nitto E,Maltoni G,Marigliano M,Zucchini S,Maffeis C,Franzese A

更新日期：2019-12-01 00:00:00

abstract：:(31)P-magnetic resonance spectroscopy ((31)P-MRS) is a non-invasive tool to study high-energy phosphate (HEP) metabolism. We evaluate whether 31P-MRS can detect early changes in kidney HEP metabolism during a 6-month trial with Valsartan. Twenty consecutive stable and normotensive kidney-transplanted patients were enr...

journal_title：Acta diabetologica

authors： Fiorina P,Bassi R,Gremizzi C,Vergani A,Caldara R,Mello A,Del Maschio A,De Cobelli F,Perseghin G,Secchi A

更新日期：2012-12-01 00:00:00

abstract：:Diabetes mellitus is an independent risk factor for falling, particularly in the elderly. Due to chronic hyperglycemia and hyperinsulinemia patients with diabetes mellitus may have neurological deficits as peripheral neuropathy that is a debilitating micro-vascular complication affecting the proximal and distal periph...

journal_title：Acta diabetologica

authors： Gioacchini FM,Albera R,Re M,Scarpa A,Cassandro C,Cassandro E

更新日期：2018-12-01 00:00:00

abstract：:Islet autotransplantation (IAT) is performed at the time of total pancreatectomy (TP) to prevent or minimize post-surgical diabetes. Corticosteroids induce insulin resistance and present a risk to islet autografts, through glucotoxicity and increased metabolic demand on a marginal islet mass. We present four IAT recip...

journal_title：Acta diabetologica

authors： Ngo A,Sutherland DE,Beilman GJ,Bellin MD

更新日期：2014-02-01 00:00:00

abstract：AIMS:Increasing evidence suggests a potential role of circulating miRNAs as clinical biomarkers, and loss of miRNA-126 has been proposed as a predictor of type 2 diabetes onset. However, a systematic analysis of circulating miRNAs in type 1 diabetic patients with micro-/macrovascular complications has not yet been perf...

journal_title：Acta diabetologica

authors： Barutta F,Bruno G,Matullo G,Chaturvedi N,Grimaldi S,Schalkwijk C,Stehouwer CD,Fuller JH,Gruden G

更新日期：2017-02-01 00:00:00

abstract：:We investigated whether food supplementation within the first year life or age at introduction of gluten-containing foods influenced the risk of developing islet autoimmunity and type 1 diabetes. A total of 2,291 children with a family history of type 1 diabetes were prospectively followed from birth for 28,983 patien...

journal_title：Acta diabetologica

authors： Chmiel R,Beyerlein A,Knopff A,Hummel S,Ziegler AG,Winkler C

更新日期：2015-06-01 00:00:00

abstract：:The relationship between insulin responses to glucose and to arginine was studied in non-obese women with previous gestational diabetes (PGD). One group, n = 10, had normal glucose tolerance (NGT) by WHO criteria and another, n = 8, had impaired glucose tolerance (IGT). A third group of women without PGD, n = 12, was ...

journal_title：Acta diabetologica

authors： Alvarsson M,Wajngot A,Efendic S,Grill V

更新日期：1995-06-01 00:00:00

abstract：:The aim of this research was the evaluation of polymorphonuclear leukocyte (PMN) membrane fluidity in subjects with insulin resistance. Insulin sensitivity, in fact, may be influenced by plasma membrane fluidity. We enrolled 19 subjects with insulin resistance previously demonstrated during an euglycemic hyperinsuline...

journal_title：Acta diabetologica

authors： Caimi G,Sinagra D,Canino B,Scarpitta AM,Montana M,Bonaventura V,Lo Presti R

更新日期：2000-03-01 00:00:00

abstract：AIMS:To examine the relationships between type 2 diabetes (T2D) status, glycemic control, and T2D duration with magnetic resonance imaging (MRI)-derived neuroimaging measures in European Americans from the Diabetes Heart Study (DHS) Mind cohort. METHODS:Relationships were examined using marginal models with generalize...

journal_title：Acta diabetologica

authors： Raffield LM,Cox AJ,Freedman BI,Hugenschmidt CE,Hsu FC,Wagner BC,Xu J,Maldjian JA,Bowden DW

更新日期：2016-06-01 00:00:00

abstract：AIMS:This study aimed to assess islet insulin secretion and insulin resistance in Chinese patients with latent autoimmune diabetes in adults (LADA). METHODS:Twelve patients with LADA, 10 with type 1 diabetes mellitus (T1DM), 10 with type 2 diabetes mellitus (T2DM), and 10 nondiabetic healthy controls (HCs) were includ...

journal_title：Acta diabetologica

authors： Yang L,Liu X,Liang H,Cheng Y,Huang G,Zhou Z

更新日期：2019-11-01 00:00:00

abstract：:Consistent with the postulated role of oxidative stress in the etiology of late diabetic complications, pharmacological interventions based on biological antioxidants have been suggested. The aim of the present study was to investigate the effect of dietary supplementation with the pyridoindole antioxidant stobadine o...

journal_title：Acta diabetologica

authors： Stefek M,Sotnikova R,Okruhlicova L,Volkovova K,Kucharska J,Gajdosik A,Gajdosikova A,Mihalova D,Hozova R,Tribulova N,Gvozdjakova A

更新日期：2000-01-01 00:00:00

abstract：:Autonomic nervous dysfunction is considered to be one of the mechanisms of metabolic syndrome (MetS). The aim of this study is to investigate whether resting heart rate, a marker of autonomic nervous dysfunction, is a predictor of MetS in apparently healthy non-obese [body mass index (BMI) <25 kg/m(2)] Japanese men. T...

journal_title：Acta diabetologica

authors： Oda E,Aizawa Y

更新日期：2014-02-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate and compare continuous subcutaneous insulin infusion (CSII) use in pediatric and adult age groups. METHODS:Data were collected with a questionnaire sent by e-mail to CSII-experienced Diabetes Centers. The questionnaire assessed: (1) number of CSII-treated patients; (2) patient...

journal_title：Acta diabetologica

authors： Bonfanti R,Lepore G,Bozzetto L,Corsi A,Di Blasi V,Girelli A,Grassi G,Iafusco D,Rabbone I,Schiaffini R,Laviola L,Bruttomesso D,Italian Study Group on Diffusion of CSII in Italy.

更新日期：2016-06-01 00:00:00

abstract：AIMS:Familial partial lipodystrophy (FPLD) is a rare autosomal dominant disorder, mostly due to mutations in lamin A (LMNA) or in peroxisome proliferator-activated receptor gamma (PPARG) genes. In the present study, we aimed to identify and functionally characterize the genetic defect underlying FPLD in an Italian fami...

journal_title：Acta diabetologica

authors： Padova G,Prudente S,Vinciguerra F,Sudano D,Baratta R,Bellacchio E,Trischitta V,Vallone A,Sciacca L,Frittitta L

更新日期：2020-05-01 00:00:00

abstract：:Urinary angiotensin-converting enzyme (ACE) and urinary N-acetyl-beta-D-glucosaminidase (NAG) were measured after a 5-year interval in 38 non-azotemic type 2 diabetic patients. Of these patients at baseline, 16 had nil nephropathy, 15 had incipient nephropathy, and 7 had overt nephropathy. During the follow-up, 6 and ...

journal_title：Acta diabetologica

authors： Miyauchi E,Hosojima H,Morimoto S

更新日期：1995-10-01 00:00:00

abstract：AIM:To identify the potential metabolite markers in diabetic retinopathy (DR) by using gas chromatography coupled with time-of-flight mass spectrometry (GC-TOFMS). METHODS:GC-TOFMS spectra were acquired from vitreous and aqueous humor (AH) samples of patients with DR and non-diabetic participants. Comparative analysis...

journal_title：Acta diabetologica

authors： Wang H,Fang J,Chen F,Sun Q,Xu X,Lin SH,Liu K

更新日期：2020-01-01 00:00:00

abstract：AIMS:We sought to investigate temporal trends in prediabetes prevalence among US adolescents using two definitions and evaluate relationships with obesity and a MetS-severity score. METHODS:We evaluated data from 5418 non-Hispanic white, non-Hispanic black, and Hispanic adolescents aged 12-19 participating in the Nati...

journal_title：Acta diabetologica

authors： Lee AM,Fermin CR,Filipp SL,Gurka MJ,DeBoer MD

更新日期：2017-04-01 00:00:00

abstract：:The purpose of this study is to identify the recent characteristics and the developments of therapeutic education in diabetes through an analysis of the international articles published from 2004 to 2007. Studies were selected from several databases: Medline, Embase, Eric, Cochrane central database, using the followin...

journal_title：Acta diabetologica

authors： Albano MG,Crozet C,d'Ivernois JF

更新日期：2008-12-01 00:00:00

abstract：:We assessed the efficacy of noninsulin antidiabetic medications used in current clinical practice (metformin, sulfonylureas, α-glucosidase inhibitors, thiazolidinediones, glinides, dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 agonists) to reach the HbA1c target <7% in people with type 2 diabetes. MEDLINE...

journal_title：Acta diabetologica

authors： Esposito K,Chiodini P,Ceriello A,Giugliano D

更新日期：2014-04-01 00:00:00

abstract：:Cardiovascular risk is determined by multiple risk factors, all of which greatly increase the chance of morbidity and mortality. So-called "normal" levels of these factors are not biologically normal, so current strategy is based on estimations of a person's global cardiovascular risk, and then using appropriate combi...

journal_title：Acta diabetologica

authors： Sleight P

更新日期：2005-04-01 00:00:00

abstract：:The aim of the study was to report the prevalence of obesity indices in individuals with diabetes and find out their association with diabetic retinopathy in the urban Indian population. Subjects (n = 1,414) were recruited from Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular Genetics Study (SN-DREAM...

journal_title：Acta diabetologica

authors： Raman R,Rani PK,Gnanamoorthy P,Sudhir RR,Kumaramanikavel G,Sharma T

更新日期：2010-09-01 00:00:00

abstract：AIMS:Type 2 diabetes (DM2) is associated to oxidative modifications of high-density lipoproteins (HDL), which can interfere with their function. Pioglitazone has proved effective in raising HDL cholesterol (HDL-C) and lowering small dense low-density lipoprotein (LDL), but no clinical studies have examined its effect o...

journal_title：Acta diabetologica

authors： Sartore G,Chilelli NC,Seraglia R,Ragazzi E,Marin R,Roverso M,Cosma C,Vaccaro O,Burlina S,Lapolla A

更新日期：2019-05-01 00:00:00

abstract：AIMS:To investigate whether intravitreal conbercept injection affects contralateral untreated eyes in bilateral diabetic macular edema (DME) patients. METHODS:In this retrospective study, 15 patients (30 eyes) with type 2 diabetes were followed after bilateral DME diagnosis in the Department of Ophthalmology, Peking U...

journal_title：Acta diabetologica

authors： Di Y,Li Z,Ye J,Li L,Li B,Yu R

更新日期：2020-08-01 00:00:00

abstract：AIMS:In patients with type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) and liver fibrosis is frequent and presumably associated with increased cardiovascular disease risk and mortality. The objective was to investigate risk factors associated with hepatic fibrosis in patients with type 2 diabetes and NAFLD to...

journal_title：Acta diabetologica

authors： Mansour A,Mohajeri-Tehrani MR,Samadi M,Gerami H,Qorbani M,Bellissimo N,Poustchi H,Hekmatdoost A

更新日期：2019-11-01 00:00:00

abstract：AIMS:To assess the metabolic health of obese and non-obese women at high GDM risk 5 years postpartum. METHODS:This is a secondary analysis of the 5-year follow-up of the RADIEL GDM prevention study including 333 women at high GDM risk (BMI ≥ 30 kg/m2 and/or previous GDM). Five years postpartum metabolic health was ass...

journal_title：Acta diabetologica

authors： Huvinen E,Eriksson JG,Koivusalo SB,Grotenfelt N,Tiitinen A,Stach-Lempinen B,Rönö K

更新日期：2018-05-01 00:00:00

abstract：:Elevated plasma CT-pro-vasopressin (copeptin) has been described as biomarkers for type 2 diabetes (T2D) and the metabolic syndrome (MetS), which, however, was not confirmed by all studies. Here, we analyzed the association of copeptin with T2D, MetS and MetS components in the population-based KORA F4 study. Plasma co...

journal_title：Acta diabetologica

authors： Then C,Kowall B,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Rathmann W,Seissler J

更新日期：2015-02-01 00:00:00

abstract：:The objective is to assess the effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar rats, 8-week-old, were categorized into four groups, which were the control (n = 9), diabetes (n = 9), infliximab-treated diabetes (n = 10), and FR167653-treated diabetes (n = 9) groups...

journal_title：Acta diabetologica

authors： Moriwaki Y,Inokuchi T,Yamamoto A,Ka T,Tsutsumi Z,Takahashi S,Yamamoto T

更新日期：2007-12-01 00:00:00