Abstract:
:Plant sucking heteropteran bugs feed regularly on small amounts of K(+)-rich plant material, in contrast to their hematophagous relatives which imbibe large volumes of Na(+)-rich blood. It was anticipated that this would be reflected in the endocrine control of Malpighian tubule (MT) secretion. To explore this, neuroendocrine factors known to influence MT secretion were tested on MT of the pentatomid plant sucking stink bugs, Acrosternum hilare and Nezara viridula, and the results compared with previously published data from Rhodnius prolixus. Serotonin had no effect on N. viridula MT, although it stimulates secretion by R. prolixus MT >1000-fold, and initiates a rapid diuresis to remove excess salt and water from the blood meal. Kinins had no effect on stink bug MT, but secretion was increased by Zoone-DH, a CRF-like peptide, although the response was a modest 2-3-fold acceleration compared with 1000-fold in R. prolixus. Native CAPA peptides, which have diuretic activity in dipteran flies, had antidiuretic activity in MT of the stink bug (Acrhi/Nezvi-CAPA-1 and -2), as previously shown with Rhopr-CAPA-2 in R. prolixus. The antidiuretic activity of Rhopr-CAPA-2 has been linked with terminating the rapid diuresis, but results with stink bugs suggest it is a general feature of heteropteran MT.
journal_name
Peptidesjournal_title
Peptidesauthors
Coast GM,TeBrugge VA,Nachman RJ,Lopez J,Aldrich JR,Lange A,Orchard Idoi
10.1016/j.peptides.2009.09.017subject
Has Abstractpub_date
2010-03-01 00:00:00pages
468-73issue
3eissn
0196-9781issn
1873-5169pii
S0196-9781(09)00375-1journal_volume
31pub_type
杂志文章相关文献
PEPTIDES文献大全abstract::Obestatin is purported to be a peptide hormone encoded in preproghrelin. We studied the metabolic effects of continuous infusion of obestatin via subcutaneously implanted osmotic mini-pumps. Administration of up to 500nmol/kg body weight/day obestatin did not change 24h cumulative food intake or body weight in rats. S...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2008.03.023
更新日期:2008-08-01 00:00:00
abstract::A lectin was isolated from extracts of fruiting bodies of the mushroom Xerocomus spadiceus using a procedure that involved ion exchange chromatography on DEAE-cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on CM-cellulose, and gel filtration by fast protein liquid chromatography o...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2003.11.013
更新日期:2004-01-01 00:00:00
abstract::To study structure-activity relationships of growth hormone-releasing hormone (GHRH), a competitive binding assay was developed using cloned porcine adenopituitary GHRH receptors expressed in human kidney 293 cells. Specific binding of [His1, 125I-Tyr10,Nle27]hGHRH(1-32)-NH2 increased linearly with protein concentrati...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(95)02026-8
更新日期:1995-01-01 00:00:00
abstract::The major active product of ghrelin gene is a 28-amino acid peptide acylated at the serine 3 position with an octanoyl group, called simply ghrelin. Ghrelin has a multiplicity of physiological functions, affecting GH release, food intake, energy and glucose homeostasis, gastrointestinal, cardiovascular, pulmonary and ...
journal_title:Peptides
pub_type: 杂志文章,评审
doi:10.1016/j.peptides.2008.02.018
更新日期:2008-07-01 00:00:00
abstract::Since its discovery, many physiologic functions have been ascribed to ghrelin, a gut derived hormone. The presence of a median fatty acid side chain on the ghrelin peptide is required for the binding and activation of the classical ghrelin receptor, the growth hormone secretagogue receptor (GHSR)-1a. Ghrelin O-acyl tr...
journal_title:Peptides
pub_type: 杂志文章,评审
doi:10.1016/j.peptides.2011.08.020
更新日期:2011-11-01 00:00:00
abstract::The C-terminus of the transcription factor p53 seems to play an important role by controlling the specific DNA-binding activity, which is directly associated with sensing damaged DNA. Another region located in the N-terminus of the protein has also been shown to regulate the DNA-binding activity of the protein. This a...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(03)00047-0
更新日期:2003-03-01 00:00:00
abstract::Peptides of the short neuropeptide F (sNPF) family have been shown to modulate feeding behavior in a wide variety of insect species. While these peptides stimulate feeding and food-searching behavior in Drosophila melanogaster and Apis mellifera, an opposite effect has recently been demonstrated in the desert locust, ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2013.09.018
更新日期:2014-03-01 00:00:00
abstract::Mastoparan (MP) peptides, distributed in insect venoms, induce a local inflammatory response post envenomation. Most endogenous MPs share common structural elements within a tetradecapeptide sequence that adopts an amphipathic helix whilst traversing biological membranes and when bound to an intracellular protein targ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2018.01.007
更新日期:2018-03-01 00:00:00
abstract::Obesity is a chronic inflammatory disease significantly risen worldwide, especially among children. Adipokines, secreted from adipose tissue, are hormones involved in various cellular processes such as energy metabolism and inflammation. Among the others, adiponectin is gaining increasing interest for its insulin-sent...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2014.11.007
更新日期:2015-01-01 00:00:00
abstract::Guinea pig VIP differs from VIP of several mammals by its amino acids in positions 5, 9, 19 and 26. We tested a) its ability to occupy VIP receptors in liver and lung membranes of rat and guinea pig and in the human lymphoblastic SUP-T1 cell line and b) the ensuing adenylate cyclase stimulation. In liver and lung memb...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(91)90180-w
更新日期:1991-01-01 00:00:00
abstract::A functional study has been performed to characterise the Y receptors responsible for NPY, PYY and PP-stimulated responses in mouse colonic mucosal preparations. Electrogenic ion secretion was stimulated with VIP following which NPY, PYY and PP analogues were, to varying degrees, inhibitory. PYY(3-36), hPP, Gln(23)hPP...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(01)00355-2
更新日期:2001-03-01 00:00:00
abstract::Angiotensin (Ang)--a peptide that is part of the renin-angiotensin system-induces vasoconstriction and a subsequent increase in blood pressure; Ang peptides, especially AngII, can also act as potent pro-inflammatory mediators. Platelet-activating factor (PAF) is a potent phospholipid mediator that is implicated in man...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2015.09.002
更新日期:2015-11-01 00:00:00
abstract::Amylin and the structurally and functionally related peptide calcitonin gene-related peptide (CGRP) have been shown to reduce food intake in rats. The aim of the present study was to compare the anorectic potency of both peptides over a wide dose range when administered into the lateral brain ventricle (ICV). Furtherm...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(98)00114-4
更新日期:1998-01-01 00:00:00
abstract::An antifungal peptide with a molecular mass of 9412 and an N-terminal sequence exhibiting notable homology to those of lipid transfer proteins was isolated from seeds of the vegetable Brassica campestris. The purification protocol entailed ion exchange chromatography on Q-Sepharose, affinity chromatography on Affi-gel...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2007.06.028
更新日期:2007-08-01 00:00:00
abstract::Originally characterized in terms of its gastric acid inhibitory properties, GIP (gastric inhibitory polypeptide) expressed in the upper small intestine, was subsequently shown to exert strong glucose-dependent insulin-releasing properties. This action is generally attributed to GIP(1-42) and, so far, no evidence for ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(95)00090-7
更新日期:1995-01-01 00:00:00
abstract::Histidyl-proline diketopiperazine (cyclo(His-Pro), a metabolite of the neuropeptide thyrotropin releasing hormone, has been shown to possess intrinsic biological activities. The binding of this peptide to various tissue particulate preparations was investigated. While the peptide showed no apparent binding to particul...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(83)90172-9
更新日期:1983-01-01 00:00:00
abstract::A 20-kDa protein with substantial N-terminal sequence homology to thaumatin-like proteins was isolated from ripe fruits of the emperor banana, Musa basjoo cv. 'emperor banana'. The isolation procedure entailed (NH(4))(2)SO(4) precipitation, ion exchange chromatography on DEAE-cellulose, and affinity chromatography on ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2007.01.005
更新日期:2007-04-01 00:00:00
abstract::Pharmacological experiments suggest that satiation associated with intestinal infusion of several nutrients is mediated by CCK-A receptors. Otsuka Long-Evans Tokushima Fatty, (OLETF), rats do not express CCK-A receptors and are insensitive to the satiation-producing effects of exogenous CCK. To further evaluate the ro...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(01)00461-2
更新日期:2001-08-01 00:00:00
abstract::A comparison of the conformational characteristics of the related hormones [Nle(15)] gastrin-17 and [Tyr(9)-SO(3)] cholecystokinin-15, in membrane-mimetic solutions of dodecylphosphocholine micelles and water, was undertaken using NMR spectroscopy to investigate the possibility of a structural motif responsible for th...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2007.09.008
更新日期:2007-11-01 00:00:00
abstract::Dermorphin, injected intracerebroventricularly (ICV) to rats, provokes, like to morphine, an inhibition of intestinal propulsion linearly related to the log of the administered doses (in the range from 0.06 to 0.56 micrograms/rat), but it is 143 times more active than morphine. Naloxone, ICV or IP, antagonizes dermorp...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(83)90165-1
更新日期:1983-01-01 00:00:00
abstract::The pentapeptide pGlu-Asn-Cyt-Pro-Arg [AVP(4-8), termed ZNC(C)PR in this article] has been found as a metabolite of arginine-vasopressin (AVP) in rat brain and has been shown to have potent memory-enhancing activity and to yield a series of biochemical events in brain tissues. [35S]ZNC(C)PR was chemically synthesized ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(94)90153-8
更新日期:1994-01-01 00:00:00
abstract::The role of central neuropeptide Y (NPY) in the cardiovascular response to social stress was evaluated in freely moving rats using telemetry. In unstressed rats, intracerebroventricular (ICV) administration of NPY and the selective Y1 receptor agonist [Leu31, Pro34]-NPY decreased blood pressure and heart rate, while t...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(97)00266-0
更新日期:1998-01-01 00:00:00
abstract::The opioid peptides, [3H]DAGO and [3H]DPDPE, bound to rat and guinea pig brain homogenates with a high, nanomolar affinity and to a high density of mu and delta receptors, respectively. [3H]DAGO binding to mu receptors was competitively inhibited by unlabelled opioids with the following rank order of potency: DAGO gre...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(89)90135-6
更新日期:1989-05-01 00:00:00
abstract::Peptides may act through G protein-coupled receptors to influence cardiovascular performance; thus, delineating mechanisms involved in signaling is a molecular-based strategy to influence health. Molecular switches, often represented by conserved motifs, maintain a receptor in an inactive state. However, once the swit...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2015.07.012
更新日期:2015-09-01 00:00:00
abstract::The effect of arginine vasopressin (AVP) on rat antinociception was investigated. Intraventricular injection of 50 or 100 ng AVP dose-dependently increased the pain threshold; in contrast, intraventricular injection of 10 microl anti-AVP serum decreased the pain threshold; both intrathecal injection of 200 ng AVP or 1...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2006.08.019
更新日期:2006-12-01 00:00:00
abstract::To determine if insulin-like growth factor (IGF)-1 and -2, FSH, or leptin alter IGF-binding protein (IGFBP)-2, -3, -4, and -5 mRNA levels in bovine granulosa and (or) theca cells, granulosa and theca cells were collected from bovine ovarian follicles, plated for 48 h in 10% FCS and then treated for 24 h in serum-free ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2004.07.008
更新日期:2004-12-01 00:00:00
abstract::As a novel vasoactive peptide, plasma coupling factor 6 (CF6) was shown to be elevated in patients with diabetes mellitus, yet the mechanism involved is unknown. We studied CF6 protein release and its potential mechanism in human umbilical vein endothelial cells (HUVECs) incubated with high glucose levels. High glucos...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2006.11.006
更新日期:2007-03-01 00:00:00
abstract::Growing evidence suggests that the neuropeptide Y (NPY) system plays an important role in the immune system. Yet, little is known about the expression of NPY and receptors in the immune system. Moreover, original contradicting results have confused the picture and hampered a clear understanding of its role in the immu...
journal_title:Peptides
pub_type: 杂志文章,评审
doi:10.1016/j.peptides.2006.09.030
更新日期:2007-02-01 00:00:00
abstract::Previous studies have shown that different calcitonins interact with planar lipid membranes to form ion channels. In this study, glycosylation of eel calcitonin (eCt) at different positions (Ct3-GlcNAc, Ct14-GlcNAc, Ct20-GlcNAc, Ct26-GlcNAc) is shown to preserve molecular structure and slightly change the energy of in...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2005.09.011
更新日期:2006-04-01 00:00:00
abstract::The puromycin-sensitive aminopeptidase (ApPS) is a zinc metallopeptidase involved in the degradation of neuropeptides. Putative catalytic residues of the enzyme, Cys146, Glu338, and Lys396 were mutated, and the resultant mutant enzymes characterized. ApPS C146S exhibited normal catalytic activity, ApPS E338A exhibited...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2003.07.012
更新日期:2003-09-01 00:00:00