Incidence of cystoid macular edema after cataract surgery in patients with and without uveitis using optical coherence tomography.

Abstract:

PURPOSE:To determine the incidence of cystoid macular edema (CME) after cataract surgery among eyes with and without uveitis using optical coherence tomography (OCT) and to determine risk factors for postoperative CME among eyes with uveitis. DESIGN:Prospective, comparative cohort study. METHODS:Single-center, academic practice. Forty-one eyes with uveitis and 52 eyes without uveitis underwent clinical examination and OCT testing within 4 weeks before cataract surgery and at 1-month and 3-month postoperative visits. The main outcome measure was incidence of CME at 1 and 3 months after surgery. RESULTS:Both uveitic and control eyes gained approximately 3 lines of vision (P = .6). Incidence of CME at 1 month was 12% (5 eyes) for uveitis and 4% (2 eyes) for controls (P = .2). Incidence of CME at 3 months was 8% (3 eyes) for uveitis and 0% for eyes without uveitis (P = .08). Eyes with uveitis treated with perioperative oral corticosteroids had a 7-fold reduction in postoperative CME (relative risk [RR], 0.14; P = .05). In uveitic eyes, active inflammation within 3 months before surgery increased the risk of CME when compared with eyes without inflammation (RR, 6.19; P = .04). CME was significantly associated with poorer vision (P = .01). CONCLUSIONS:Eyes with well-controlled uveitis may obtain similar outcomes to control eyes after cataract surgery (up to 3 months). Use of perioperative oral corticosteroids and control of uveitis for more than 3 months before surgery seemed to decrease the risk of postoperative CME among uveitic eyes in this study.

journal_name

Am J Ophthalmol

authors

Bélair ML,Kim SJ,Thorne JE,Dunn JP,Kedhar SR,Brown DM,Jabs DA

doi

10.1016/j.ajo.2009.02.029

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

128-35.e2

issue

1

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(09)00151-2

journal_volume

148

pub_type

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