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Correlation between clinical suspicion and polymerase chain reaction verification of infectious vitritis.

Abstract：

PURPOSE:To compare polymerase chain reaction (PCR) results to presumptive clinical diagnosis in patients with vitritis. DESIGN:Retrospective review of PCR laboratory records from vitreous samples. METHODS:Fifty consecutive laboratory records of vitreous samples sent for PCR testing were reviewed. Three reviewers with uveitis training ranked the clinical suspicion of a specific diagnosis using a classification system (scale of 1 to 4) and were masked to the PCR results. RESULTS:The degree of clinical suspicion of a particular diagnosis was significantly associated with a positive PCR result (P = .048). Higher clinical suspicion was significantly more associated with a positive PCR result compared with cases with lower clinical suspicion (P = .01). CONCLUSIONS:If the clinical suspicion of a specific diagnosis is low, the PCR for any infectious etiology is unlikely to be positive.

journal_name

Am J Ophthalmol

journal_title

American journal of ophthalmology

authors

Acharya N,Lietman T,Cevallos V,Whitcher JP,Saidel M,Stone D,Duncan J,Margolis TP

doi

10.1016/j.ajo.2005.10.011

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

584-5

issue

3

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(05)01088-3

journal_volume

141

pub_type

杂志文章

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