Iris color and intraocular pressure: the Blue Mountains Eye Study.

Abstract:

PURPOSE:To assess the relationship between iris color and intraocular pressure (IOP). DESIGN:Population-based, cross-sectional study. METHODS:The Blue Mountains Eye Study examined 3,654 largely Caucasian participants, aged 49 to 97 years, from 1992 to 1994. Information was collected about glaucoma risk factors, and Goldmann applanation IOP measurements were taken. Iris color was assessed by comparing the undilated appearance of each eye with three standard photographs. Participants who had previous cataract or glaucoma surgery and those using glaucoma medications were excluded. RESULTS:Mean IOP measurements increased with increasing grades of iris pigmentation. After simultaneous adjustment for variables associated with IOP, mean measurements were 15.92 mm Hg for blue iris color, 16.04 mm Hg for hazel or green, 16.11 mm Hg for tan-brown, and 16.49 mm Hg for dark brown (P for trend = .001). CONCLUSIONS:This study demonstrates a modest but statistically significant association between increasing iris color and IOP.

journal_name

Am J Ophthalmol

authors

Mitchell R,Rochtchina E,Lee A,Wang JJ,Mitchell P,Blue Mountains Eye Study.

doi

10.1016/s0002-9394(02)01967-0

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

384-6

issue

3

eissn

0002-9394

issn

1879-1891

pii

S0002939402019670

journal_volume

135

pub_type

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