Abstract：
:Dipivalyl epinephrine, 0.1%, though slightly less effective in decreasing intraocular pressure, showed significantly fewer side effects than epinephrine hydrochloride, 2%. Seventeen patients with symmetrically increased intraocular pressures who completed a six-month double-masked crossover study showed a significant decrease in intraocular pressure averaging 23.7% for dipivalyl epinephrine over the entire study and 27.4% for epinephrine. In the first treatment period, dipivalyl epinephrine was slightly less effective than epinephrine. In the second treatment period, dipivalyl epinephrine was statistically less effective than epinephrine. Two of the original 25 patients were dropped from the study because of epinephrine allergy or intolerance, one had uncontrolled pressures with either drug, and five failed to maintain adequate follow-up. Complaints of side effects such as burning and irritation occurred much more frequently in eyes receiving epinephrine (24%) than dipivalyl epinephrine (3%). Mild mydriasis occurred with each drug, averaging +0.65 mm with dipivalyl epinephrine and +0.55 mm Hg with epinephrine. No effect on blood pressure or pulse rate was found for the two drugs.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Kohn AN,Moss AP,Hargett NA,Ritch R,Smith H Jr,Podos SMdoi
10.1016/0002-9394(79)90142-9subject
Has Abstractpub_date
1979-02-01 00:00:00pages
196-201issue
2eissn
0002-9394issn
1879-1891pii
0002-9394(79)90142-9journal_volume
87pub_type
临床试验,杂志文章,随机对照试验abstract：:A prospective study of ophthalmologic findings in 20 African patients with the acquired immunodeficiency syndrome (Group 1) and nine patients with acquired immune deficiency syndrome related complex (Group 2) disclosed that 11 patients in Group 1 and two patients in Group 2 had ocular involvement. Cotton-wool spots, R...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90787-1
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abstract：:Although asymmetric or unilateral optic disk swelling is unusual in patients with increased intracranial pressure, we treated three such patients. Two (a 31-year-old man and a 31-year-old woman, both of whom were overweight) had benign intracranial hypertension. The third patient (a 64-year-old man) had a posterior fo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77912-7
更新日期：1983-10-01 00:00:00
abstract：PURPOSE:To assess agreement between structural and functional testing in classifying eyes as normal or abnormal and their repeatability on two consecutive visits by means of standard automated perimetry (SAP) and confocal scanning laser ophthalmoscopy. DESIGN:Analysis of selected data obtained from a prospective longi...
journal_title：American journal of ophthalmology
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更新日期：2006-09-01 00:00:00
abstract：PURPOSE:To assess the efficacy and safety of adjunctive daunorubicin during vitrectomy surgery in eyes with idiopathic proliferative vitreoretinopathy (PVR). METHODS:Two hundred eighty-six eyes (286 patients) with stage C2 (Retina Society Classification, 1983) or more advanced preoperative PVR in which surgery with si...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期：1998-10-01 00:00:00
abstract：PURPOSE:To compare the surgical outcomes of ocular surface squamous neoplasia (OSSN) following wide excisional biopsy with and without primary simple limbal epithelial transplantation (p-SLET). DESIGN:Nonrandomized clinical study with historical controls. METHODS:setting: Single-institutional study. PATIENTS:Eight p...
journal_title：American journal of ophthalmology
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abstract：:We performed visual contrast sensitivity testing with Regan's low-contrast letter charts on 30 patients with optic neuropathies and good Snellen visual acuity. Results of this testing were compared with color vision and the presence of an afferent pupillary defect. Regan's low-contrast letter charts were found to be 9...
journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
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abstract：:Pars plana vitrectomy and scleral buckling were performed on 22 eyes of 19 patients for treatment of perforating eye injuries from shotgun pellets. We reviewed the intraoperative findings at the time of vitrectomy to determine what factors might influence final visual acuity. The presence of a total retinal detachment...
journal_title：American journal of ophthalmology
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更新日期：1992-07-15 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：1979-10-01 00:00:00
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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更新日期：1999-12-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2002-07-01 00:00:00
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journal_title：American journal of ophthalmology
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doi：10.1016/j.ajo.2005.06.022
更新日期：2005-10-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：2014-11-01 00:00:00
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1981-04-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1980-05-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：2006-01-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：1983-12-01 00:00:00
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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更新日期：1975-07-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：2006-08-01 00:00:00
abstract：PURPOSE:To determine the spectrum of conjunctival flora and the antibiotic susceptibility profiles of patients undergoing cataract surgery at a Midwestern university. DESIGN:Prospective in vitro laboratory investigation of a patient cohort. METHODS:Conjunctival cultures were obtained from patients undergoing cataract...
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journal_title：American journal of ophthalmology
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