Melanocytoma of the ciliary body and iris.

abstract：PURPOSE:To describe patients with late-onset pseudoxanthoma elasticum (PXE) associated with a likely hypomorphic ABCC6 variant. DESIGN:Retrospective observational case series. METHODS:Clinical evaluation, multimodal retinal imaging, genetic testing, and molecular modeling. RESULTS:Three patients, in whom vision symp...

journal_title：American journal of ophthalmology

authors： Charbel Issa P,Tysoe C,Caswell R

更新日期：2020-10-01 00:00:00

abstract：:In August 1989, the Tokyo Metropolitan Government officially began a vision screening program for children aged 3 years 1 month. A 1988 pilot study of 1,303 children this age disclosed five cases (0.38%) of amblyopia. The home vision test, which uses picture cards of familiar figures, proved to be an efficient and ine...

journal_title：American journal of ophthalmology

authors： Yazawa K,Suga J,Wakita S,Sumitomo M,Uemura Y

更新日期：1992-10-15 00:00:00

abstract：PURPOSE:To report a rare case of craniodiaphysial dysplasia (CDD) that resulted in a profound loss of vision in both eyes. DESIGN:Observational case report. METHODS:A 2-year-old girl presented with midfacial anomaly. Marked thickening and sclerosis in the calvaria and facial bones were detected on the plain x-rays, w...

journal_title：American journal of ophthalmology

authors： Kim CH,Oh DE,Kim YD

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:To report outcomes of Vogt-Koyanagi-Harada (VKH) disease from a clinical trial of antimetabolite therapies. DESIGN:Subanalysis from an observer-masked randomized clinical trial for noninfectious intermediate, posterior, and panuveitis. METHODS:setting: Clinical practice at Aravind Eye Hospitals, India. PATIE...

journal_title：American journal of ophthalmology

authors： Shen E,Rathinam SR,Babu M,Kanakath A,Thundikandy R,Lee SM,Browne EN,Porco TC,Acharya NR

更新日期：2016-08-01 00:00:00

abstract：:Ocular abnormalities were present in five of 11 patients with Freeman-Sheldon syndrome. The predominant ocular findings were strabismus and blepharoptosis. Stiffness of the extraocular muscles, demonstrated in three patients by forced duction testing, made surgery difficult. Two patients underwent frontalis muscle sli...

journal_title：American journal of ophthalmology

authors： O'Keefe M,Crawford JS,Young JD,Macrae WG

更新日期：1986-09-15 00:00:00

abstract：PURPOSE:To report a case of conjunctival intraepithelial neoplasia presenting as corneal ulcer. METHOD:Case report of a 28-year-old man who presented with sudden onset of pain, redness, and watering in the right eye. Examination of right cornea revealed deep stromal infiltrate inferonasally. Adjacent to the infiltrate...

journal_title：American journal of ophthalmology

authors： Sridhar MS,Honavar SG,Vemuganti G,Rao GN

更新日期：2000-01-01 00:00:00

abstract：:A 5-month-old infant girl died of familial lymphohistiocytosis. The central nervous system showed widespread perivascular infiltration of the cerebral pia and arachnoid, the cerebral white matter and deep gray matter, the cerebellum, and brain stem by lymphocytes, benign appearing histiocytes, and macrophages with ery...

journal_title：American journal of ophthalmology

authors： Appen RE,Weber SW,de Venecia G,Rhein GM

更新日期：1976-11-01 00:00:00

abstract：:Subconjunctival 5-fluorouracil has been an effective adjunct in glaucoma filtering surgery. We investigated the effectiveness of 5-fluorouracil in primary trabeculectomy combined with phacoemulsification and posterior chamber intraocular lens implantation (glaucoma triple procedure). Seventy-four patients were enrolle...

journal_title：American journal of ophthalmology

authors： O'Grady JM,Juzych MS,Shin DH,Lemon LC,Swendris RP

更新日期：1993-11-15 00:00:00

abstract：PURPOSE:To analyze the comparative safety and efficacy of two techniques of corneal neurotization (CN) (direct corneal neurotization [DCN] vs indirect corneal neurotization [ICN]) for the treatment of neurotrophic keratopathy (NK). DESIGN:Multicenter interventional prospective comparative case series. METHODS:This st...

journal_title：American journal of ophthalmology

authors： Fogagnolo P,Giannaccare G,Bolognesi F,Digiuni M,Tranchina L,Rossetti L,Dipinto A,Allevi F,Lozza A,Rabbiosi D,Mariani S,Pellegrini M,Cazzola FE,Bagaglia S,Mazzotta C,Gabriele G,Gennaro P,Badiali G,Marchetti C,Campos

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:To determine whether patients can guess their intraocular pressure (IOP). DESIGN:Patient survey. METHODS:We asked consecutive patients to guess their IOP and then indicate the IOP and the symptoms that allowed them to guess. RESULTS:Of 132 patients, 22 (17%) believed they could guess their IOP, usually based...

journal_title：American journal of ophthalmology

authors： Stewart WC,Jackson AL,Jenkins JN

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:To correlate visual acuity measured with the Optec 800 to the gold-standard Early Treatment Diabetic Retinopathy Study (ETDRS) chart. DESIGN:Prospective, cross-sectional study. METHODS:Forty patients of the Vanderbilt Eye Institute agreed to undergo visual acuity testing. Five patients were excluded because o...

journal_title：American journal of ophthalmology

authors： Kehler LF,Kehler KB,Merin LM,Tsai JC

更新日期：2007-03-01 00:00:00

abstract：:Upshoot and downshoot of the adducted eye in Duane's retraction syndrome is thought to be caused by a bridle effect of the co-contracting horizontal recti muscles. A recession of both of these muscles transposes their insertions posteriorly in relation to the center of rotation of the globe, which reduces the bridle e...

journal_title：American journal of ophthalmology

authors： von Noorden GK

更新日期：1992-09-15 00:00:00

abstract：PURPOSE:To determine the prevalence of drusen-like deposits (DLDs) and choroidal changes in patients with systemic lupus erythematosus (SLE), with or without glomerulonephritis; and to correlate ocular findings with systemic features. DESIGN:Case-control study. METHODS:Sixty patients with SLE (age, 18-55 years; 30 wi...

journal_title：American journal of ophthalmology

authors： Invernizzi A,dell'Arti L,Leone G,Galimberti D,Garoli E,Moroni G,Santaniello A,Agarwal A,Viola F

更新日期：2017-03-01 00:00:00

abstract：:There is no single method of perimetric examination which is applicable to all types of visual field defects. Perimetry is a subjective psychophysical sensory examination. It is not an exact science unless one includes the objective measurement of visual evoked response in the optic cortex. Until such a method becomes...

journal_title：American journal of ophthalmology

authors： Harrington DO

更新日期：1975-09-01 00:00:00

abstract：PURPOSE:To evaluate the association between scleritis and systemic disease in a non-university, non-tertiary referral practice and to describe our experience with scleritis treatment. DESIGN:Retrospective chart review. METHODS:The medical records of patients with scleritis between 2001 and 2007 were reviewed for asso...

journal_title：American journal of ophthalmology

authors： Raiji VR,Palestine AG,Parver DL

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:To characterize spontaneous dislocation of the fluocinolone acetonide sustained release implant (Retisert; Bausch & Lomb) drug pellet from its strut. DESIGN:Retrospective, observational case series. METHODS:The medical records of 224 patients in whom 407 fluocinolone acetonide implants were placed by either o...

journal_title：American journal of ophthalmology

authors： Itty S,Callanan D,Jones R,Pecen P,Martel J,Jaffe GJ

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To report the echographic appearance of a scleral fold in hypotony. METHOD:We performed ultrasonography on a patient who, after trabeculectomy with mitomycin C, had an intraocular pressure of 1 mm Hg, an opaque cataract, and suspected hypotonous maculopathy in the left eye. RESULTS:An area of dome-shaped eyew...

journal_title：American journal of ophthalmology

authors： Loewenstein A,McKinnon S,DiBernardo C

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:In juvenile X-linked retinoschisis (XLRS), fluorescein angiography is usually unremarkable and contributes poorly to the diagnosis. However, indocyanine green (ICG) angiography features in eyes that are affected with XLRS were not yet described. DESIGN:Retrospective observational case series. METHODS:A comple...

journal_title：American journal of ophthalmology

authors： Souied EH,Goritsa A,Querques G,Coscas G,Soubrane G

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:Periocular injection of corticosteroids is a common treatment for vision loss in patients with intermediate uveitis. However, this treatment has the potential for serious side effects. We sought to determine the effects of such injections in a series of patients. METHODS:We reviewed charts of 20 consecutive pa...

journal_title：American journal of ophthalmology

authors： Helm CJ,Holland GN

更新日期：1995-07-01 00:00:00

abstract：:A 61-year-old white woman, who had progressive arthritis over a two-year period, developed bilateral peripheral corneal degeneration. The superior cornea thinned to a thickness of approximately two thirds of normal. She died suddenly in the hospital and a primary occlusive vasculitis of the anterior ciliary arteries w...

journal_title：American journal of ophthalmology

authors： Austin P,Green WR,Sallyer DC,Walsh FB,Kleinfelter HT

更新日期：1978-03-01 00:00:00

abstract：PURPOSE:To determine whether cataract in patients with atopic dermatitis is associated with higher levels of aqueous flare or cells. METHODS:In a prospective study, 35 consecutive patients examined during a 6-month period at the atopic dermatitis service in a university hospital underwent standardized ophthalmologic e...

journal_title：American journal of ophthalmology

authors： Matsuo T,Saito H,Matsuo N

更新日期：1997-07-01 00:00:00

abstract：:We performed a histologic study to support our clinical observations on the mechanisms responsible for traction retinal detachment after a penetrating injury in the rhesus monkey eye. The monkey eyes (40 eyes; 40 monkeys) were characterized by intraocular fibrosis with the formation of a cyclitic membrane and epiretin...

journal_title：American journal of ophthalmology

authors： Cleary PE,Ryan SJ

更新日期：1979-08-01 00:00:00

abstract：PURPOSE:To investigate the effect of refractive astigmatism on all-distance visual acuity (VA) in eyes implanted with a diffractive trifocal or bifocal intraocular lens (IOL). DESIGN:Cross-sectional study. METHODS:Fifty eyes with trifocal IOLs (PanOptix; Alcon) and 50 eyes with bifocal IOLs (ReSTOR +3D) were enrolled...

journal_title：American journal of ophthalmology

authors： Hayashi K,Yoshida M,Igarashi C,Hirata A

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:Immune checkpoint inhibitors (ICI) targeting the programmed cell death protein 1 (PD-1), or its ligand PD-L1, are the mainstay of metastatic cancer treatment. Patients receiving these treatments may develop immune-related adverse events (irAEs). This study aimed to estimate the prevalence and describe the clini...

journal_title：American journal of ophthalmology

authors： Bitton K,Michot JM,Barreau E,Lambotte O,Haigh O,Marabelle A,Voisin AL,Mateus C,Rémond AL,Couret C,Champiat S,Labetoulle M,Rousseau A

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To report histopathologic confirmation of the internal limiting membrane (ILM) using triamcinolone acetonide (TA). DESIGN:Interventional case report. METHODS:One eye of one patient who underwent macular hole repair using TA suspension to help visualize the internal limiting membrane (ILM). The specimen was se...

journal_title：American journal of ophthalmology

authors： Shah GK,Rosenblatt BJ,Smith M

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:To describe hypotony caused by erosion of the conjunctiva and sclera by a silicone scleral buckle. METHODS:Interventional case report. A 33-year-old man with Marfan syndrome presented with hypotony maculopathy and a collapsed globe 17 months after repair of retinal detachment with a silicone sponge and silicon...

journal_title：American journal of ophthalmology

authors： Deramo VA,Haupert CL,Fekrat S,Postel EA

更新日期：2001-09-01 00:00:00

abstract：PURPOSE:To compare the intraocular pressure (IOP)-lowering efficacy and safety of netarsudil once daily (QD) and timolol twice daily (BID). DESIGN:Double-masked, randomized, phase 3, noninferiority study. METHODS:Patients with open-angle glaucoma or ocular hypertension (unmedicated baseline IOP >20 to <30 mm Hg at 8:...

journal_title：American journal of ophthalmology

authors： Khouri AS,Serle JB,Bacharach J,Usner DW,Lewis RA,Braswell P,Kopczynski CC,Heah T,Rocket-4 Study Group.

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To determine whether delayed repair of traumatic canalicular laceration affects the final outcome. DESIGN:Retrospective case series. METHODS:The medical records of 334 patients who underwent primary traumatic canalicular laceration repair were retrospectively reviewed. Patients were divided into 2 groups acco...

journal_title：American journal of ophthalmology

authors： Chu YC,Wu SY,Tsai YJ,Liao YL,Chu HY

更新日期：2017-10-01 00:00:00

abstract：:Although asymmetric or unilateral optic disk swelling is unusual in patients with increased intracranial pressure, we treated three such patients. Two (a 31-year-old man and a 31-year-old woman, both of whom were overweight) had benign intracranial hypertension. The third patient (a 64-year-old man) had a posterior fo...

journal_title：American journal of ophthalmology

authors： Sedwick LA,Burde RM

更新日期：1983-10-01 00:00:00

abstract：:Sebaceous adenocarcinoma (meibomian gland cancer) can be localized at times to one specific area of the eyelid; at other times, it spreads diffusely by pagetoid invasion throughout the conjunctiva. The pagetoid spread is often impossible to visualize. I used a map biopsy of the conjunctiva to determine the extent of i...

journal_title：American journal of ophthalmology

authors： Putterman AM

更新日期：1986-07-15 00:00:00