Abstract：
:We performed a histologic study to support our clinical observations on the mechanisms responsible for traction retinal detachment after a penetrating injury in the rhesus monkey eye. The monkey eyes (40 eyes; 40 monkeys) were characterized by intraocular fibrosis with the formation of a cyclitic membrane and epiretinal and subretinal membranes. The progression to a fibrous ingrowth from the wound occurred only in eyes with blood in the vitreous. The intravitreal fibroblastic proliferation had its origin mainly from the stroma of the ciliary body and choroid at the wound but probably also from the nonpigmented ciliary epithelium. A fibroblastic response was present within the vitreous as early as four days after injury, and had progressed to form a cyclitic membrane by six weeks. Epiretinal membranes were identified as early as four weeks after injury. They were most prominent over the peripheral retina anterior to the equator. It is likely that they are derived from multiple cellular sources including the fibrous ingrowth from the wound but they were also connected to the surface of the retina by bridges of tissue indicating a glial origin. The subretinal membranes appeared to be derived from both retinal pigment epithelium cells and glial cells.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Cleary PE,Ryan SJdoi
10.1016/0002-9394(79)90469-0subject
Has Abstractpub_date
1979-08-01 00:00:00pages
221-31issue
2eissn
0002-9394issn
1879-1891pii
0002-9394(79)90469-0journal_volume
88pub_type
杂志文章abstract：PURPOSE:To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with 1 to 7 years of follow-up. DESIGN:Retrospective, noncomparative, consecutive case series. METHODS:Eighty-seven consecutive eyes of 79 patients with previous closure of the macular ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.11.006
更新日期：2011-05-01 00:00:00
abstract：PURPOSE:To describe a Japanese patient with incomplete congenital stationary night blindness (iCSNB) with atypical retinal atrophy and kinetic visual field defects. METHODS:An ophthalmologic examination was performed, and the CACNA1F gene was analyzed by direct genomic sequencing. RESULTS:The patient had a hemizygous...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01541-6
更新日期：2002-09-01 00:00:00
abstract：PURPOSE:To evaluate the rate of peripapillary choroidal thinning in glaucoma patients and healthy controls using spectral domain optical coherence tomography. DESIGN:Cohort study. METHODS:Participants from the multicenter African Descent and Glaucoma Evaluation Study and Diagnostic Innovations in Glaucoma Study were ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2017.10.025
更新日期：2018-02-01 00:00:00
abstract：:A 71-year-old woman had von Willebrand's disease, an inheritable abnormality of platelet activity, and developed diabetic retinal neovascularization. A 59-year-old man had a myeoloproliferative disorder with thrombocythemia but may have had retinal changes before the development of his platelet dysfunction. The occurr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90749-9
更新日期：1979-07-01 00:00:00
abstract：PURPOSE:To estimate incidence of age-related macular degeneration (AMD) by subtype in American whites aged ≥50 years. DESIGN:Systematic review and meta-analysis. METHODS: SETTING:Prospective cohort studies of AMD incidence in populations of white European ancestry published in MEDLINE, EMBASE, and Web of Science. S...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ajo.2015.04.003
更新日期：2015-07-01 00:00:00
abstract：PURPOSE:To determine the association between cystoid macular edema and vascular endothelial growth factor concentration in the aqueous humor and plasma of uveitis patients. METHODS:Cross-sectional study. Vascular endothelial growth factor concentrations were measured by enzyme-linked immunosorbent assay in the aqueous...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01103-5
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:To perform a comprehensive review and to investigate the presence and role of autoimmune antibodies in 25 cases of acute zonal occult outer retinopathy (AZOOR) identified using the classification originally proposed by J. Donald Gass. DESIGN:Observational case series. METHODS:Setting: Institutional. STUDY PO...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.12.001
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:To compare the outcome of primary anterior chamber vs secondary scleral-fixated intraocular lens (IOL) implantation in complicated cataract surgeries. DESIGN:Retrospective, comparative study. METHODS:A consecutive series of complicated cataract surgeries with primary anterior chamber (ACIOL) or secondary scle...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.10.016
更新日期：2015-02-01 00:00:00
abstract：PURPOSE:To describe a modified technique of haptic externalization during repositioning of dislocated posterior chamber lens implants, which facilitates placement of scleral fixation sutures around the haptic for implant stabilization. METHODS:We describe a technique of repositioning a dislocated posterior chamber imp...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00650-4
更新日期：2001-01-01 00:00:00
abstract：:We studied 1,000 eyes of 500 subjects in an attempt to discover a relationship between lattice and snail track degenerations of the peripheral retina. Because of the clinical similarities between these two degeneration lesions, we suggest that snail track degeneration is either a variant of or an early stage of lattic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90639-5
更新日期：1981-10-01 00:00:00
abstract：PURPOSE:To evaluate the effects of a dexamethasone intravitreous drug delivery system (dexamethasone DDS) in patients with persistent macular edema (ME) resulting from uveitis or Irvine-Gass syndrome. DESIGN:Randomized, prospective, single-masked, controlled trial. METHODS:Three hundred and fifteen patients with pers...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ajo.2008.12.033
更新日期：2009-06-01 00:00:00
abstract：:In several tumors of different organ sites, the amount of DNA in a cell (ploidy) is associated with malignancy. We performed DNA quantitation in 21 choroidal melanomas and compared flow cytometry with image analysis in 11 of these melanomas. We modified our preparation technique to overcome problems with pigment and c...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73592-5
更新日期：1993-03-15 00:00:00
abstract：PURPOSE:To compare the intraocular pressure (IOP) values during a 3-month period after implantation of the new Visian Implantable Collamer Lens (ICL; STAAR Surgical Company, Nidau, Switzerland) V4c design with CentraFLOW technology without iridotomy using a standard procedure followed by implantation of the conventiona...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.05.018
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:To investigate the value of whole-body positron emission tomography/computed tomography (PET/CT) as a screening tool for patients with uveal metastasis. DESIGN:Retrospective observational case series. METHODS:setting: Clinical practice. study population: Eighteen patients with uveal metastatic tumors were eva...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.09.028
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:To report a case of bilateral acute retinal necrosis caused by cytomegalovirus. METHODS:A diagnostic vitrectomy was performed on a patient with non-Hodgkin lymphoma who presented with a bilateral, rapidly progressing necrotizing retinitis and uveitis. RESULTS:Immunohistochemical studies and polymerase chain r...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00250-5
更新日期：1999-01-01 00:00:00
abstract：:The extent of visual function loss from nuclear cataractous change can be estimated by observing the extinction of blue light compared to white light as a function of sagittal lens depth in standard slit lamps. Apparent extinction (loss of transmissivity) of 50% or more of the depth of the lens in blue light of maxima...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90057-x
更新日期：1981-05-01 00:00:00
abstract：PURPOSE:We performed a histopathologic and immunohistologic study to determine the macromolecular and cellular components of subfoveal neovascular membranes removed at the time of submacular surgery. METHODS:Subfoveal neovascular membranes were surgically removed from ten patients (seven with age-related macular degen...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72158-0
更新日期：1995-09-01 00:00:00
abstract：PURPOSE:To evaluate the postoperative status of the macula after vitreous surgery with internal limiting membrane removal for macular hole related retinal detachment in patients with severe myopia. DESIGN:Interventional case series. METHODS:We prospectively examined 10 eyes with retinal detachment associated with a m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00186-7
更新日期：2003-08-01 00:00:00
abstract：:In a retrospective review from 1972 through 1987 of patients with microbial keratitis, fungal infection occurred in four (4%) of 90 cosmetic or aphakic contact lens wearers and in four (27%) of 15 patients using a therapeutic soft contact lens. Predisposing factors included improper lens care by the refractive lens we...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90705-2
更新日期：1988-12-15 00:00:00
abstract：:We reviewed the results of vitreous surgery in 12 eyes of 12 patients with tractional macular detachment from Toxocara canis. We performed a vitrectomy and membrane peeling in all eyes, with additional scleral buckling in four eyes. After a minimum of six months' follow-up, ten of the 12 eyes (83%) had complete retina...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73253-2
更新日期：1989-07-15 00:00:00
abstract：PURPOSE:To report the incidence and risk factors of elevated IOP following deep anterior lamellar keratoplasty (DALK). DESIGN:A retrospective case series. METHODS:A retrospective study investigating the 5-year incidence of raised IOP following DALK cases performed from 2004 to 2008 in a tertiary center. Patients with...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.07.025
更新日期：2016-10-01 00:00:00
abstract：:Fluorescein angiography was safely performed in 100 consecutive cases of cataract extraction during the first postoperative week. Seventy-five percent of the 100 eyes had good quality fluorescein angiograms. Four eyes demonstrated cystoid macular edema. Therefore, the incidence of cystoid macular edema in the first we...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90126-4
更新日期：1976-05-01 00:00:00
abstract：PURPOSE:To assess the long-term stability of sutured scleral-fixated posterior chamber intraocular lenses (PCIOLs) performed in combination with pars plana vitrectomy. DESIGN:Retrospective, consecutive, interventional case series. METHODS:Retrospective single-surgeon study of 118 eyes of 111 patients seen at Retina C...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.01.034
更新日期：2018-05-01 00:00:00
abstract：:A patient, initially examined at the age of 16 years and monitored for almost two decades, had corneal warpage and keratoconus associated with contact lens wear. Although the patient was advised repeatedly of the risk of continued contact lens use, she persisted. Contact-lens corrected visual acuity continued to deter...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90678-6
更新日期：1985-10-15 00:00:00
abstract：PURPOSE:To report the clinicopathologic findings in patient with optic nerve sheath hemangiopericytoma. DESIGN:Clinicopathologic report. METHODS:The clinical, histologic, and immunohistochemical findings of a patient with optic nerve sheath hemangiopericytoma were reviewed. RESULTS:An excisional biopsy of an optic n...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.11.046
更新日期：2007-05-01 00:00:00
abstract：PURPOSE:Patients with idiopathic nystagmus syndrome often develop an abnormal head position. A horizontal face turn can be treated with the augmented Kestenbaum procedure, while patients with a chin up or chin down position can be treated with surgery on the vertical recti and/or oblique muscles. Although rare, some pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.04.034
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To evaluate an optical coherence tomography (OCT)-guided, variable-dosing regimen with intravitreal ranibizumab for the treatment of patients with neovascular age-related macular degeneration (AMD). DESIGN:Open-label, prospective, single-center, nonrandomized, investigator-sponsored clinical study. METHODS:In...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/j.ajo.2007.01.028
更新日期：2007-04-01 00:00:00
abstract：:A 68-year-old white man with a documented family history of Reis-Bücklers' corneal dystrophy had a penetrating keratoplasty of the right eye in 1962. In 1977, vision decreased and foreign body sensation returned. Examination indicated a Reis-Bücklers' dystrophy that had appeared in the graft 15 years after the transpl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75256-0
更新日期：1978-04-01 00:00:00
abstract：PURPOSE:To compare optic disk size in eyes of subjects classified as normal with the eyes of subjects with open-angle glaucoma, ocular hypertension, or pseudoexfoliation syndrome in an older population-based sample. METHODS:The Blue Mountains Eye Study examined 3,654 subjects. Vertical disk diameter was measured from ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00195-6
更新日期：1999-10-01 00:00:00
abstract：PURPOSE:The purpose of this study was to compare the perioperative parameters of quadrant, sextant, and grid lens fragmentation patterns in femtosecond laser-assisted cataract surgery (FLACS). DESIGN:Prospective randomized clinical trial. METHODS:Setting: Eye Center of the Second Affiliated Hospital, School of Medici...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2019.12.017
更新日期：2020-05-01 00:00:00
