Ocular and cerebral involvement in familial lymphohistiocytosis.

abstract：:We conducted a two-part study to determine whether any positive association between the use of allopurinol and the development of cataracts could be demonstrated. Study 1 included 251 Boston-area patients hospitalized for cataract and 753 matched controls. Two cataract patients were regular allopurinol users as compar...

journal_title：American journal of ophthalmology

authors： Jick H,Brandt DE

更新日期：1984-09-15 00:00:00

abstract：PURPOSE:To report the clinical outcomes of penetrating keratoplasty (PK) after autologous cultivated limbal epithelial transplantation in eyes with limbal stem cell deficiency (LSCD) after ocular surface burns. DESIGN:Retrospective case series. METHODS:This study included 47 patients with unilateral LSCD treated by a...

journal_title：American journal of ophthalmology

authors： Basu S,Mohamed A,Chaurasia S,Sejpal K,Vemuganti GK,Sangwan VS

更新日期：2011-12-01 00:00:00

abstract：:We used wide-field color specular microscopy of the human corneal surface to study the morphologic changes that occur under extended-wear contact lenses. There was a shift in the frequency distribution of surface cells by size to larger cells, suggesting a prolonged residence time on the ocular surface. Other abnormal...

journal_title：American journal of ophthalmology

authors： Lemp MA,Gold JB

更新日期：1986-03-15 00:00:00

abstract：PURPOSE:To compare the clinical outcomes of two treatment approaches for bilateral nasolacrimal duct obstruction (NLDO) in infancy. DESIGN:Multicenter, randomized clinical trial. METHODS:We studied 57 infants between the ages of 6 and <10 months who had bilateral NLDO. Participants were randomized to receive either (...

journal_title：American journal of ophthalmology

authors： Lee KA,Chandler DL,Repka MX,Melia M,Beck RW,Summers CG,Frick KD,Foster NC,Kraker RT,Atkinson S,PEDIG.

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To assess the clinical outcomes of currently used refractive surgery procedures performed in 2015. DESIGN:Prospective, multicenter cohort study. METHODS:This prospective study included 15 011 eyes of 7622 consecutive patients who underwent laser in situ keratomileusis (LASIK), surface ablation, refractive len...

journal_title：American journal of ophthalmology

authors： Kamiya K,Igarashi A,Hayashi K,Negishi K,Sato M,Bissen-Miyajima H,Survey Working Group of the Japanese Society of Cataract and Refractive Surgery.

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:To describe a case of bone marrow transplantation retinopathy in a patient in the absence of prior radiation therapy. METHODS:Case report. RESULTS:Bilateral scotomata developed in a 26-year-old woman because of a retinal microvasculopathy two years after receiving an autologous bone marrow transplantation for...

journal_title：American journal of ophthalmology

authors： Cunningham ET Jr,Irvine AR,Rugo HS

更新日期：1996-08-01 00:00:00

abstract：PURPOSE:To determine the frequency of ocular adverse effects associated with vemurafenib (PLX4032) treatment for metastatic cutaneous melanoma. DESIGN:Retrospective review of the clinical study reports from the clinical pharmacology, phase 1, phase 2, and phase 3 trials of vemurafenib. METHODS:The vemurafenib clinica...

journal_title：American journal of ophthalmology

authors： Choe CH,McArthur GA,Caro I,Kempen JH,Amaravadi RK

更新日期：2014-10-01 00:00:00

abstract：:Of a series of 57 formerly amblyopic patients who attained equal visual acuities (20/20 or better in each eye), only 29 were able to alternate after treatment. The oldest patient was 5 years old. The pattern visual-evoked response of the previously amblyopic eye in nonalternators showed a reduced amplitude as compared...

journal_title：American journal of ophthalmology

authors： Campos EC,Gulli R

更新日期：1985-01-15 00:00:00

abstract：PURPOSE:To evaluate changes in postoperative refractive outcomes following combined phacoemulsification and pars plana vitrectomy for rhegmatogenous retinal detachment (RRD) compared with other retinal diseases. DESIGN:Retrospective observational case-control study. METHODS:A total of 55 patients who had combined sur...

journal_title：American journal of ophthalmology

authors： Cho KH,Park IW,Kwon SI

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:To study the clinical characteristics of microrips of the retinal pigment epithelium (RPE) in polypoidal choroidal vasculopathy (PCV). DESIGN:Retrospective case series. METHODS:For this study, we retrospectively reviewed 156 consecutive eyes of 136 patients with PCV. The lesions were examined with fluorescein...

journal_title：American journal of ophthalmology

authors： Musashi K,Tsujikawa A,Hirami Y,Otani A,Yodoi Y,Tamura H,Yoshimura N

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To compare the prevalence of dengue maculopathy among patients hospitalized for dengue fever during a 2007 epidemic with its prevalence during the 2005 epidemic. DESIGN:Cross-sectional observational study of consecutive patients hospitalized in two general hospitals with dengue fever during the dengue epidemic...

journal_title：American journal of ophthalmology

authors： Chee E,Sims JL,Jap A,Tan BH,Oh H,Chee SP

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:To perform a quantitative trait locus (QTL) analysis and evaluate whether a locus between SIX1 and SIX6 is associated with retinal nerve fiber layer (RNFL) thickness in individuals of European descent. DESIGN:Observational, multicenter, cross-sectional study. METHODS:A total of 231 participants were recruited...

journal_title：American journal of ophthalmology

authors： Kuo JZ,Zangwill LM,Medeiros FA,Liebmann JM,Girkin CA,Hammel N,Rotter JI,Weinreb RN

更新日期：2015-07-01 00:00:00

abstract：:We studied 216 eyes of 160 patients who underwent combined phacoemulsification and posterior chamber intraocular lens implantation with trabeculectomy. The mean follow-up was 18.7 months, with a minimum follow-up of six months. To assess the safety and efficacy of a recently developed 3-mm incision procedure with fold...

journal_title：American journal of ophthalmology

authors： Lyle WA,Jin JC

更新日期：1991-02-15 00:00:00

abstract：:A 13-year-old boy developed an osteogenic sarcoma of the right humerus ten years after treatment for bilateral retinoblastoma. The bilateral retinoblastoma has been managed with enucleation of one eye and successful treatment of the solitary tumor in the other eye with a single application of a local 10-mm round cobal...

journal_title：American journal of ophthalmology

authors： Abramson DH,Ellsworth RM,Kitchin FD

更新日期：1980-09-01 00:00:00

abstract：PURPOSE:To evaluate the mechanism of spontaneous resolution of foveal detachments and idiopathic macular breaks. METHODS:We reviewed the records of 139 consecutive eyes (94 patients) with either a foveal detachment or a macular break in patients who were examined between 1989 and 1992. There were 26 men and 68 women (...

journal_title：American journal of ophthalmology

authors： Kakehashi A,Schepens CL,Akiba J,Hikichi T,Trempe CL

更新日期：1995-12-01 00:00:00

abstract：:Nine patients with polyradiculomyeloneuropathy after acute hemorrhagic conjunctivitis (AHC) infection were studied serologically. All except one patient had neutralization titers larger than or equal to 1:16 against the prototype J670/71 strain of AHC virus in at least one of their serum samples. The development of a ...

journal_title：American journal of ophthalmology

authors： Hung TP,Green IJ,Sung SM

更新日期：1975-11-01 00:00:00

abstract：:Primary oculomotor nerve synkinesis is almost always caused by an intracavernous meningioma or aneurysm. We treated a patient who had signs of primary oculomotor nerve synkinesis from an unruptured extracavernous aneurysm located at the junction of the internal carotid artery and the posterior communicating artery. Th...

journal_title：American journal of ophthalmology

authors： Varma R,Miller NR

更新日期：1994-07-15 00:00:00

abstract：:Forty-three patients who initially presented with Krikenberg's spindles but with no glaucomatous field defects were observed for an average of 5.8 years in an attempt to evaluate the prognostic implication of spindle presence. Twenty-two of the patients had been followed for a minimum of five years. Analysis of the st...

journal_title：American journal of ophthalmology

authors： Wilensky JT,Buerk KM,Podos SM

更新日期：1975-02-01 00:00:00

abstract：PURPOSE:To determine factors of uveal malignant melanoma that would help to predict prognosis in Japanese patients. METHODS:From 1969 to 1994, 23 eyes with uveal malignant melanoma were enucleated from 23 Japanese patients, and 16 of these patients were studied. In the 16 patients, enucleated eyes were evaluated for t...

journal_title：American journal of ophthalmology

authors： Sakamoto T,Sakamoto M,Yoshikawa H,Hata Y,Ishibashi T,Ohnishi Y,Inomata H

更新日期：1996-03-01 00:00:00

abstract：PURPOSE:To compare the effects of extracapsular cataract extraction with posterior chamber intraocular lens (ECCE/PC-IOL) vs intracapsular cataract extraction with aphakic glasses (ICCE-AG) on everyday visual functioning and quality of life. METHODS:In a nonmasked randomized controlled clinical trial, 3,400 bilateral ...

journal_title：American journal of ophthalmology

authors： Fletcher A,Vijaykumar V,Selvaraj S,Thulasiraj RD,Ellwein LB

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of autologous plasmin (AP)-assisted vitrectomy for stage 5 retinopathy of prematurity (ROP). DESIGN:Interventional case series. METHODS:Six consecutive eyes of four children with stage 5 ROP were treated. The patients' ages at the surgery ranged from five to eight months after birth. ...

journal_title：American journal of ophthalmology

authors： Tsukahara Y,Honda S,Imai H,Kondo N,Fujii S,Yokoyama N,Hirata A,Kawaji T,Fukushima M,Tanihara H,Negi A

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:To evaluate the ocular surface inflammatory response to the presence of preservatives in nonselective beta-blocker eyedrops. DESIGN:Prospective, crossover, single-masked, randomized clinical study. METHODS:study population: Twenty primary open-angle glaucoma or ocular hypertensive patients were divided in two...

journal_title：American journal of ophthalmology

authors： Manni G,Centofanti M,Oddone F,Parravano M,Bucci MG

更新日期：2005-01-01 00:00:00

abstract：:The technique of keratoprosthesis was used in 21 cases of severe and intractable forms of keratopathy during the past 3 1/2 years. The results in terms of visual acuity were satisfactory in more than half the cases. Significant problems that occurred after this procedure included the diagnosis and management of glauc...

journal_title：American journal of ophthalmology

authors： Rao GN,Blatt HL,Aquavella JV

更新日期：1979-08-01 00:00:00

abstract：:Bleomycin was administered to 126 normal or human-tumor-bearing baby rats we observed for the development of cataracts. Eighty-four percent of the rats receiving this drug before the age of 10 days developed lens opacities. Bleomycin given to 10-day-old rats or older did not induce cataract formation. The cataracts in...

journal_title：American journal of ophthalmology

authors： Edwards GA,Bernardino VB Jr,Babcock VI,Southam CM

更新日期：1975-09-01 00:00:00

abstract：:Fine-needle aspiration was used as a primary orbital diagnostic technique in 156 patients. A 20-mm syringe, a 22-gauge, 3.75-cm needle, and a plastic pistol grip were used. Local anesthetic was not necessary. When the needle is in the lesion, small to-and-fro movements with a minimum of angulation are helpful. The asp...

journal_title：American journal of ophthalmology

authors： Kennerdell JS,Slamovits TL,Dekker A,Johnson BL

更新日期：1985-05-15 00:00:00

abstract：PURPOSE:To evaluate the effects of a dexamethasone intravitreous drug delivery system (dexamethasone DDS) in patients with persistent macular edema (ME) resulting from uveitis or Irvine-Gass syndrome. DESIGN:Randomized, prospective, single-masked, controlled trial. METHODS:Three hundred and fifteen patients with pers...

journal_title：American journal of ophthalmology

authors： Williams GA,Haller JA,Kuppermann BD,Blumenkranz MS,Weinberg DV,Chou C,Whitcup SM,Dexamethasone DDS Phase II Study Group.

更新日期：2009-06-01 00:00:00

abstract：:Twenty-six eyes of 25 patients with chronic open-angle glaucoma and surgical aphakia with inadequate control of intraocular pressure (IOP) despite maximal medical treatment were treated with cyclocryotherapy, according to a prospective protocol and specific technique. (Neovascular and synechial glaucoma were excluded ...

journal_title：American journal of ophthalmology

authors： Bellows AR,Grant WM

更新日期：1978-05-01 00:00:00

abstract：:A 57-year-old man had a clinically suspected malignant melanoma in his left eye. On microscopic study, the enucleated eye harbored an unusual choroidal tumor that had extended extraocularly. This tumor had been variously interpreted microscopically as an angiosarcoma, an atpical angioma, a glioma, or a neurilemoma. El...

journal_title：American journal of ophthalmology

authors： Jakobiec FA,Witschel H,Zimmerman LE

更新日期：1976-08-01 00:00:00

abstract：PURPOSE:To evaluate the importance of nutritional supplements, dietary pattern, and genetic associations in age-related macular degeneration (AMD); and to discuss the technique of artificial intelligence/deep learning to potentially enhance research in detecting and classifying AMD. DESIGN:Retrospective literature rev...

journal_title：American journal of ophthalmology

authors： Chew EY

更新日期：2020-09-01 00:00:00

abstract：:To evaluate the ability of the Friedmann visual field analyzer to determine visual threshold and the depth of visual field defects, we correlated the visual threshold determined kinetically (Goldmann perimeter) with the static threshold (Friedmann analyzer) in various parts of the central field. We found the following...

journal_title：American journal of ophthalmology

authors： Hicks BC,Anderson DR

更新日期：1983-05-01 00:00:00