Abstract：
PURPOSE:To report a case of peripheral retinal nonperfusion and chronic myeloid leukemia in a 23-year-old woman. DESIGN:Observational case report. METHODS:A complete ophthalmic and systemic evaluation was performed. RESULTS:Ophthalmic examination revealed peripheral retinal nonperfusion with retinal neovascularization in both eyes. Fluorescein angiography of both eyes showed a marked midperipheral and peripheral avascular retina temporally with arteriovenous anastomosis and seafan neovascularizations. Blood work showed no abnormalities, although marked leucocytosis (up to 750 x 10(9)/l) and thrombocytosis (646 x 10(9)/l) were present in 1998 when the patient was diagnosed with leukemia. Following treatment, the patient has been in remission. CONCLUSIONS:Peripheral retinal nonperfusion with retinal neovascularization may occur as a complication of chronic myeloid leukemia. In contrast to other studies describing this association, our patient had a bilateral peripheral retinal nonperfusion with seafan neovascularizations without relapse of the myeloid leukemia and without any of the other retinal signs associated with chronic myeloid leukemia, such as tortuosity of veins, intraretinal or preretinal hemorrhages, and cotton-wool exudates.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Nobacht S,Vandoninck KF,Deutman AF,Klevering BJdoi
10.1016/s0002-9394(02)01956-6subject
Has Abstractpub_date
2003-03-01 00:00:00pages
404-6issue
3eissn
0002-9394issn
1879-1891pii
S0002939402019566journal_volume
135pub_type
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