Abstract:
PURPOSE:To evaluate the influence of the extent of myopia on the progression rate of normal-tension glaucoma (NTG). DESIGN:Retrospective, observational case series. METHODS:One hundred forty-three eyes of 143 patients with NTG who were treated from 1994 through 2006 and followed up with standard automated perimetry were evaluated in this study. The participants were divided into 4 groups: mild myopia (-0.76 to -2.99 diopters [D]), moderate myopia (-3 to -5.99 D), severe myopia (-6 D or less), and nonmyopia (emmetropia and hyperopia, -0.75 D or more) groups. The change in mean deviation, corrected pattern standard deviation, mean thresholds of 10 zones corresponding to the glaucoma hemifield test, and thresholds of 52 points of the nonmyopia group were compared with those of the other myopia groups. Additionally, we controlled each analysis for age and posttherapeutic intraocular pressure to preclude the possibility of these covariates influencing the analysis of the effect of myopia on the progression of glaucoma. RESULTS:There was no statistically significant difference between the nonmyopia group and each of the myopia groups in terms of mean deviation, corrected pattern standard deviation, mean thresholds of 10 zones corresponding to the glaucoma hemifield test, and the thresholds of 52 point changes against refraction. Moreover, with the control of the other covariates (age and posttherapeutic intraocular pressure), no statistically significant differences were noted (multivariate analysis using mixed model, P > .1). CONCLUSIONS:Although a high incidence of open-angle glaucoma among myopic patients has been reported previously, myopia did not influence the progression rate of NTG after treatment.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Sohn SW,Song JS,Kee Cdoi
10.1016/j.ajo.2009.12.033subject
Has Abstractpub_date
2010-05-01 00:00:00pages
831-8issue
5eissn
0002-9394issn
1879-1891pii
S0002-9394(09)00974-Xjournal_volume
149pub_type
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journal_title:American journal of ophthalmology
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更新日期:1987-11-15 00:00:00
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pub_type: 杂志文章,meta分析
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更新日期:2009-07-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70189-8
更新日期:1997-04-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2002-02-01 00:00:00
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doi:10.1016/s0002-9394(00)00924-7
更新日期:2001-03-01 00:00:00
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更新日期:2012-12-01 00:00:00
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更新日期:1998-12-01 00:00:00
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更新日期:2006-11-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2000-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-09-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2018-09-01 00:00:00