Abstract：
PURPOSE:To demonstrate techniques of iris reconstruction (pupilloplasty) at the time of penetrating keratoplasty (PKP) for a variety of pupil abnormalities, and to evaluate the effect of pupilloplasty on graft survival and visual outcome. DESIGN:Case-control study. METHODS:Thirty-five cases (combined PKP and pupilloplasty) and 70 controls (PKP alone) were included. Various pupil abnormalities and the surgical techniques used to correct them were reviewed and categorized. The Chi-square and Student t tests were used to compare the baseline risk factors and demographic variables between treatment and control groups. The known risk factors for corneal graft survival were analyzed by Kaplan-Meier and Cox regression methods. RESULTS:Twenty men and 15 women in the age range, 27 to 77 years underwent combined iris reconstruction and PKP with pseudophakic/aphakic bullous keratopathy being the most common indication. The mean follow-up duration was 39.12 months and eight (22.9%) grafts failed during follow-up. Iris reconstruction during PKP has a significant positive effect on long-term graft survival (hazard ratio 2.52; 95% CI, 1.14 to 5.57; P = .022). Patients with pupilloplasty also tended to have a better mean postoperative visual acuity compared to the control group (P = .40). CONCLUSIONS:Iris reconstruction is a relatively simple procedure that should be performed in eyes with substantial pupil abnormalities at the time of PKP. Pupilloplasty significantly improves graft survival, renders the pupil cosmetically more acceptable, and may improve visual outcome.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Arundhati A,Jun BZ,Janardhan P,Tan DTdoi
10.1016/j.ajo.2007.10.006subject
Has Abstractpub_date
2008-02-01 00:00:00pages
203-209issue
2eissn
0002-9394issn
1879-1891pii
S0002-9394(07)00883-5journal_volume
145pub_type
杂志文章abstract：:We studied four patients with idiopathic dilated episcleral vessels. Three of these patients had asymmetric or unilateral open-angle glaucoma in the eye with the greater degree of episcleral vascular anomaly. The fourth patient showed dilated episcleral vessels, but the intraocular pressure (IOP) was not increased. In...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90010-7
更新日期：1978-07-01 00:00:00
abstract：PURPOSE:To examine the effects of lutein and zeaxanthin supplementation on retinal function using multifocal electroretinograms (mfERG) in patients with early age-related macular degeneration (AMD). DESIGN:Randomized, double-masked, placebo-controlled trial. METHODS:One hundred eight subjects with early AMD were rand...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2012.04.014
更新日期：2012-10-01 00:00:00
abstract：PURPOSE:To determine whether patients can guess their intraocular pressure (IOP). DESIGN:Patient survey. METHODS:We asked consecutive patients to guess their IOP and then indicate the IOP and the symptoms that allowed them to guess. RESULTS:Of 132 patients, 22 (17%) believed they could guess their IOP, usually based...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/S0002-9394(03)00861-4
更新日期：2004-02-01 00:00:00
abstract：:A graft of hard palate mucosa is a satisfactory substitute for the posterior lamella of tarsus and conjunctiva in eyelid reconstruction. The graft may be harvested after administration of local anesthesia in adults, provides structural support as well as a mucosal surface, and contracts minimally. The palatal donor si...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90257-2
更新日期：1989-06-15 00:00:00
abstract：PURPOSE:To analyze the effect of intensified topical steroid therapy after Descemet membrane endothelial keratoplasty combined with cataract surgery (triple-DMEK) on the incidence of postoperative cystoid macular edema (CME). DESIGN:Single-center comparative clinical study with historical controls. METHODS: SETTING:...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.12.008
更新日期：2016-03-01 00:00:00
abstract：:Using immunohistochemical techniques, we studied ligneous conjunctival lesions from two patients. A significant immune reaction was detected that was characterized by activated T lymphocytes and focal accumulation of plasma cells and B lymphocytes. Immunofluorescent studies demonstrated that IgG was a prominent compon...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90216-x
更新日期：1989-02-15 00:00:00
abstract：:Posterior scleritis was diagnosed in four adolescent boys. These patients represented a distinct subgroup of patients with posterior scleritis that differed from the adult variant by gender, lack of systemic disease, and absence of the associated ocular findings often seen in the adult variant of the disorder. The fou...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71579-x
更新日期：1992-03-15 00:00:00
abstract：PURPOSE:To evaluate the efficacy of autologous plasmin (AP)-assisted vitrectomy for stage 5 retinopathy of prematurity (ROP). DESIGN:Interventional case series. METHODS:Six consecutive eyes of four children with stage 5 ROP were treated. The patients' ages at the surgery ranged from five to eight months after birth. ...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/j.ajo.2007.03.020
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:To determine the safety and efficacy of verteporfin photodynamic therapy (PDT) for the treatment of persistent choroidal neovascularization (CNV) previously treated with external beam radiotherapy (EBRT). DESIGN:Retrospective case series. METHODS:Verteporfin PDT was performed on 14 eyes of 13 patients with sy...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.09.019
更新日期：2005-03-01 00:00:00
abstract：:We studied accommodation and vergence eye movements in a patient with a left middle cerebral artery embolism. Accommodation was monitored by an infrared optometer with the accommodative target being controlled by a microcomputer. Computed tomography showed low-density areas in the left cortex, with intact brainstem. T...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76389-5
更新日期：1988-07-15 00:00:00
abstract：PURPOSE:To determine the relationship between quantitative nerve fiber layer measurements and visual field testing in patients with large cup-to-disk ratios. METHODS:Seventy-six patients with vertical cup-to-disk ratios by contour of at least 0.8 on stereoscopic photographs and 50 normal subjects were included. One ey...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(01)01107-2
更新日期：2001-10-01 00:00:00
abstract：PURPOSE:To determine the ciliary body thickness and other biometric findings in eyes with narrow angles. METHODS:Eighteen otherwise normal eyes with narrow angles in 18 Japanese patients and 18 normal control eyes with open angles in 18 age-matched and sex-matched Japanese patients were studied. A-scan ultrasonography...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00353-0
更新日期：2000-03-01 00:00:00
abstract：PURPOSE:To evaluate the correlation between tear film lipid layer thickness and other objective measurements such as tear film break-up time (TBUT), upper and lower meibomian gland losses, and Schirmer 1 test in patients with obstructive meibomian gland dysfunction (MGD) and normal controls. DESIGN:Cross-sectional stu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.01.008
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To evaluate the repeatability of an extensive number of relevant indices with the Pentacam HR in keratoconus of varying severity and normal eyes. DESIGN:Reliability analysis. METHODS:This study was performed at Antwerp University Hospital, Belgium, and enrolled 20 healthy volunteers (20 eyes) and 69 patients ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.06.013
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:To describe rifabutin-associated uveitis with opacities in the inferior and posterior vitreous in three patients with acquired immunodeficiency syndrome. METHOD:Case reports of the three patients are presented. RESULTS:The patients, who were being treated with rifabutin and fluconazole, developed anterior and...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72124-5
更新日期：1996-10-01 00:00:00
abstract：PURPOSE:To examine the occurrence and outcome of methicillin-resistant Staphylococcus aureus ophthalmologic infections in a newborn intensive care unit cohort. DESIGN:Noninterventional case series. METHODS:Over a 13-month period, 29 neonates were colonized with methicillin-resistant S. aureus in a newborn intensive c...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.02.019
更新日期：2006-07-01 00:00:00
abstract：PURPOSE:To report a series of patients in whom infectious scleritis developed after vitreoretinal surgery. DESIGN:Interventional case series of four patients. METHODS:Medical records of patients at a single institution in whom infectious scleritis developed after vitreoretinal surgery were reviewed. RESULTS:In three...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.11.024
更新日期：2008-04-01 00:00:00
abstract：:Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxyribonucleic acid (mtDNA). Each cell contains thousands of mitochondrial DNA molecules. We demonstrated that in certain isolated instances, the proband and close maternal lineage relatives can have mixtures of mutant a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72429-8
更新日期：1990-06-15 00:00:00
abstract：:Sebaceous adenocarcinoma (meibomian gland cancer) can be localized at times to one specific area of the eyelid; at other times, it spreads diffusely by pagetoid invasion throughout the conjunctiva. The pagetoid spread is often impossible to visualize. I used a map biopsy of the conjunctiva to determine the extent of i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90214-x
更新日期：1986-07-15 00:00:00
abstract：PURPOSE:To evaluate and compare the recurrence rates and complications between 2 therapeutic methods for primary pterygium: subconjunctival injection of mitomycin C (MMC) 1 month before bare scleral excision and conjunctival rotational flap with intraoperative MMC use. DESIGN:Prospective, interventional, randomized cl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2010.03.006
更新日期：2010-08-01 00:00:00
abstract：:A clinicopathologic and follow-up study of 56 intraocular medulloepitheliomas in the Registry of Ophthalmic Pathology revealed a mean age of five years at the time of definitive diagnosis, most patients having had a delay in surgical therapy of more than one year after onset of signs or symptoms. Histologic evidence o...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77739-6
更新日期：1978-03-01 00:00:00
abstract：PURPOSE:To document clinical features of uveitis in patients with familial juvenile systemic granulomatosis. DESIGN:Retrospective chart review. METHODS:Ophthalmologic examination, medical history, and clinical course in 16 patients from eight families examined at six academic medical centers. RESULTS:Of the 16 patie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01709-9
更新日期：2002-12-01 00:00:00
abstract：PURPOSE:To report angiographically documented cystoid macula edema associated with the use of each of the three newly available ocular hypotensive lipids: unoprostone, travaprost, and bimatoprost. DESIGN:Observational case series. METHODS:Retrospective review of three patients in a clinical practice who had uncontrol...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01411-8
更新日期：2002-03-01 00:00:00
abstract：PURPOSE:To demonstrate that hairy cell leukemia may involve the eye. METHODS:We examined a patient who had a unique ocular manifestation of hairy cell leukemia with severe panuveitis in one eye and leukemic retinopathy in the fellow eye. RESULTS:Therapy with 2-chloro-deoxy-adenosine, a drug recently introduced for tr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70543-4
更新日期：1996-01-01 00:00:00
abstract：:Senior-Loken syndrome is a rare hereditary disease that combines a disorder resembling familial juvenile nephronophthisis with retinitis pigmentosa. Retinitis pigmentosa is even less frequently associated with exudative retinopathy. The patient, a 15-year-old boy, had hereditary renal-retinal dystrophy combined with a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73374-4
更新日期：1985-12-15 00:00:00
abstract：PURPOSE:The purpose of this report is to review the clinical variations and natural course of Coats disease, using strict diagnostic guidelines. METHODS:In a retrospective, consecutive series, Coats disease was defined as idiopathic retinal telangiectasia with intraretinal or subretinal exudation without appreciable s...
journal_title：American journal of ophthalmology
pub_type：
doi：10.1016/s0002-9394(00)00883-7
更新日期：2001-05-01 00:00:00
abstract：:The prevalence of diabetic retinopathy was lower in a rural diabetic population when compared to the prevalence of diabetic retinopathy in medical center clinic populations. Adult-onset (Type II) diabetics were at greater risk for developing diabetic retinopathy shortly after diagnosis than newly diagnosed cases of ju...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90502-6
更新日期：1984-06-01 00:00:00
abstract：PURPOSE:To assess the relative distribution in the cornea of amyloid and (beta)ig-h3 gene product in lattice corneal dystrophy type IIIA (LCD-IIIA). METHODS:Serial sections from the cornea of a patient with LCD-IIIA were subjected to either Congo red staining or immunohistochemistry employing an antibody to (beta)ig-h...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00360-2
更新日期：1999-04-01 00:00:00
abstract：:Amyloid fibrils occurring in primary and myeloma-associated (AL), secondary (AA), and certain neuropathic hereditary forms of systemic amyloidosis can be distinguished biochemically or immunohistologically as being composed of immunoglobulin light chain, protein AA, or prealbumin respectively. All types of systemic an...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(87)90357-6
更新日期：1984-08-15 00:00:00
abstract：PURPOSE:To study patients diagnosed with retinal angiomatous proliferation (RAP) based on conventional imaging techniques with phase-resolved Doppler optical coherence tomography (OCT) to detect and localize blood flow in RAP lesions; and to compare these findings to conventional imaging, which are mostly invasive and ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.07.026
更新日期：2015-11-01 00:00:00
