当前位置： SCI文献检索 > AMERICAN JOURNAL OF OPHTHALMOLOGY期刊下所有文献 > Verteporfin photodynamic therapy for the treatment of persistent subfoveal choroidal neovascularization after external beam radiotherapy: one-year results.

Verteporfin photodynamic therapy for the treatment of persistent subfoveal choroidal neovascularization after external beam radiotherapy: one-year results.

Abstract：

PURPOSE:To determine the safety and efficacy of verteporfin photodynamic therapy (PDT) for the treatment of persistent choroidal neovascularization (CNV) previously treated with external beam radiotherapy (EBRT). DESIGN:Retrospective case series. METHODS:Verteporfin PDT was performed on 14 eyes of 13 patients with symptomatic leakage from CNV previously treated by EBRT. Principal outcome measures were: comparison of visual acuity at 12 months post-PDT with baseline and the recording of any ocular or systemic adverse events. RESULTS:At baseline, the mean logMAR (+/-SD) VA was 0.81 +/- 0.33, whereas at the 12-month point it was 0.89 +/- 0.43 (P = .326). At the 12-month examination 10 eyes had lost less than 3 lines of VA, and 8 eyes had lost less than 1.5 lines. During this time, there were 2.1 PDT treatment sessions per eye on average (range = 1 to 4). There were no ocular or systemic adverse events recorded. CONCLUSIONS:This short-term study shows that verteporfin PDT is safe after EBRT and may be of benefit for recalcitrant CNV.

journal_name

Am J Ophthalmol

journal_title

American journal of ophthalmology

authors

Gupta R,Browning AC,Wu K,Sokal M,Amoaku WM

doi

10.1016/j.ajo.2004.09.019

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

561-2

issue

3

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(04)01110-9

journal_volume

139

pub_type

杂志文章

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