Corticosteroid therapy for optic disc neovascularization secondary to chronic uveitis.

Abstract:

PURPOSE:To report successful corticosteroid treatment of optic disc neovascularization associated with uveitis. METHODS:Retrospective review of medical records. RESULTS:Nine patients were identified with chronic uveitis and optic disc neovascularization without clinical or angiographic evidence of retinal ischemia. Ages ranged from 14 to 37 years (median age, 27). All patients were treated with either oral and/or subtenon's corticosteroids. Partial regression of the neovascularization was observed in all patients within 2 to 6 weeks (median, 5 weeks) after initiating treatment. Eight of nine patients had complete resolution of disc neovascularization at a median of 3 months (range, 2 to 42 months) after initiation of treatment and a median follow-up of 24 months (range, 7 to 144 months). Recurrence of disc neovascularization occurred in two patients, but it regressed again after further corticosteroid therapy. CONCLUSIONS:Optic disc neovascularization may occur in patients with chronic uveitis in the absence of retinal ischemia. This neovascularization can be successfully treated with corticosteroids.

journal_name

Am J Ophthalmol

authors

Sanislo SR,Lowder CY,Kaiser PK,Gutman FA,Zegarra H,Dodds EM,Dailey JP,Meisler DM,Cunningham ET

doi

10.1016/s0002-9394(00)00598-5

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

724-31

issue

6

eissn

0002-9394

issn

1879-1891

pii

S0002939400005985

journal_volume

130

pub_type

杂志文章
  • Broken semiflexible intraocular lens implant.

    abstract::The haptic of a semiflexible anterior chamber intraocular lens (Kelman Quadraflex) broke inside the eye of a 70-year-old man. No history of major eye or head trauma could be elicited from the patient. Clinical manifestations included inferior corneal edema progressing toward the optical axis resulting from a free-floa...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(85)90226-0

    authors: Maguen E,Nesburn AB,Jackman N,Macy JI

    更新日期:1985-02-15 00:00:00

  • Corneal toxicity and inflammation secondary to retained perfluorodecalin.

    abstract:PURPOSE:To describe a case with bullous keratopathy and anterior segment inflammation associated with heavy liquids. DESIGN:Observational case report. METHODS:Review of clinical and histopathologic changes. RESULTS:A 65-year-old patient underwent a pars plana vitrectomy for a rhegmatogenous retinal detachment. Perfl...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2005.01.034

    authors: Cauchi P,Azuara-Blanco A,McKenzie J

    更新日期:2005-08-01 00:00:00

  • Vitrectomy for a persisting macular fold in a case of resolved hypotony maculopathy.

    abstract:PURPOSE:To describe a patient with resolved hypotony maculopathy with a persistent retinal fold (despite normalization of intraocular pressure [IOP]) who underwent successful surgical intervention by vitrectomy, internal limiting membrane peel, and gas tamponade. DESIGN:Interventional case report. METHODS:A 55-year-o...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.03.024

    authors: Benson SE,Barton K,Gregor ZJ

    更新日期:2004-09-01 00:00:00

  • Subfoveal choroidal thickness as a potential predictor of visual outcome and treatment response after intravitreal ranibizumab injections for typical exudative age-related macular degeneration.

    abstract:PURPOSE:To investigate the prognostic implication of subfoveal choroidal thickness on treatment outcome after intravitreal ranibizumab injections for typical exudative age-related macular degeneration (AMD). DESIGN:Retrospective study. METHODS:A total of 40 eyes of 37 patients who completed 6-month follow-up were ana...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2014.01.019

    authors: Kang HM,Kwon HJ,Yi JH,Lee CS,Lee SC

    更新日期:2014-05-01 00:00:00

  • Bacterial endophthalmitis associated with exposed monofilament sutures following corneal transplantation.

    abstract::Three cases of bacterial endophthalmitis following corneal transplantation resulted from suture abscesses that were initiated by loose or broken exposed sutures. Histopathologic examination clearly demonstrated that the infection gained access to the anterior chamber by following a deeply placed suture that traversed ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(85)90217-x

    authors: Confino J,Brown SI

    更新日期:1985-02-15 00:00:00

  • Separate and combined effects of timolol maleate and acetazolamide in open-angle glaucoma.

    abstract::We compared the intraocular pressure-decreasing effect of timolol maleate alone, acetazolamide alone, and combined timolol and acetazolamide therapy in nine patients with bilateral chronic open-angle glaucoma. Timolol decreased intraocular pressure at least as effectively as acetazolamide. The two medications together...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)75631-4

    authors: Berson FG,Epstein DL

    更新日期:1981-12-01 00:00:00

  • The effects of posterior subtenon injection of triamcinolone acetonide in patients with intermediate uveitis.

    abstract:PURPOSE:Periocular injection of corticosteroids is a common treatment for vision loss in patients with intermediate uveitis. However, this treatment has the potential for serious side effects. We sought to determine the effects of such injections in a series of patients. METHODS:We reviewed charts of 20 consecutive pa...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)73759-6

    authors: Helm CJ,Holland GN

    更新日期:1995-07-01 00:00:00

  • Biochmical aspects of contact lens wear.

    abstract::Glycogen, adenosine triphosphate, and hydration were measured in rabbit corneal epithelium to determine whether the corneal epithelium glycogen decrease, increase in epithelial hydration, and decrease in epithelial adenosine triphosphate stores, seen as a result of contact lens wear, were secondary only to anoxia or m...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(75)90884-3

    authors: Thoft RA,Friend J

    更新日期:1975-07-01 00:00:00

  • Frequency Doubling Technology Perimetry and Changes in Quality of Life of Glaucoma Patients: A Longitudinal Study.

    abstract:PURPOSE:To evaluate the relationship between rates of change on frequency doubling technology (FDT) perimetry and longitudinal changes in quality of life (QoL) of glaucoma patients. DESIGN:Prospective observational cohort study. METHODS:One hundred fifty-two subjects (127 glaucoma and 25 healthy) were followed for an...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2015.04.007

    authors: Abe RY,Gracitelli CP,Diniz-Filho A,Zangwill LM,Weinreb RN,Medeiros FA

    更新日期:2015-07-01 00:00:00

  • Surgical treatment of retinal detachments complicated by proliferative vitreoretinopathy.

    abstract::During the last four years we treated 82 consecutive patients (83 eyes) with retinal detachments complicated by proliferative vitreoretinopathy. We used pars plana vitrectomy combined with a broad scleral buckle, cryotherapy to the retinal breaks, and a temporary intraocular gas bubble. The retina was successfully rea...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(84)90683-4

    authors: de Bustros S,Michels RG

    更新日期:1984-12-15 00:00:00

  • Prevalence of ocular disease in a population study of subjects 65 years old and older.

    abstract::During a two-year period a randomly selected age-stratified sample of subjects 65 years old and older living in Gisborne, New Zealand, was examined by an ophthalmologist to investigate visual acuity and the prevalence of the major disorders of vision in old age. A total of 481 subjects (a response rate of 86.2%) compl...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(82)90073-3

    authors: Martinez GS,Campbell AJ,Reinken J,Allan BC

    更新日期:1982-08-01 00:00:00

  • Optic nerve infarction.

    abstract::In three cases infarction in the inferotemporal prelaminar portion of the optic disk resulted in shallow cupping and arcuate visual field defects. Such changes occurred acutely, were not progressive, and required no treatment. ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)77720-7

    authors: Lichter PR,Henderson JW

    更新日期:1978-03-01 00:00:00

  • Chronic central serous chorioretinopathy imaged by optical coherence tomographic angiography.

    abstract:PURPOSE:To describe optical coherence tomographic (OCT) angiography findings in chronic central serous chorioretinopathy (CSC), and to characterize their OCT B-scans by means of the split-spectrum amplitude-decorrelation angiography algorithm. DESIGN:Evaluation of an imaging technique in a cohort of patients. METHODS...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2015.06.016

    authors: Quaranta-El Maftouhi M,El Maftouhi A,Eandi CM

    更新日期:2015-09-01 00:00:00

  • Diabetic retinopathy and insulin therapy in a rural diabetic population.

    abstract::The prevalence of diabetic retinopathy was lower in a rural diabetic population when compared to the prevalence of diabetic retinopathy in medical center clinic populations. Adult-onset (Type II) diabetics were at greater risk for developing diabetic retinopathy shortly after diagnosis than newly diagnosed cases of ju...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(84)90502-6

    authors: Kollarits CR,Kiess RD,Das A,Hall AM,Jordan EL Jr,Donovan JE

    更新日期:1984-06-01 00:00:00

  • Extraocular muscle cysticercosis presenting as Brown syndrome.

    abstract:PURPOSE:Report of a case of acquired Brown syndrome caused by infestation of the superior oblique muscle by Cysticercus cellulosae. METHOD:Case seen in a referral practice. A 20-year-old man presented with recurrent attacks of conjunctivitis and diplopia in upgaze. Clinical examination of ocular motility established a...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(00)00818-7

    authors: Pandey PK,Chaudhuri Z,Bhatia A

    更新日期:2001-04-01 00:00:00

  • Asymmetric canthaxanthin retinopathy.

    abstract:PURPOSE/METHODS:We studied a case of crystalline retinopathy occurring after prolonged use of oral canthaxanthin. The patient was followed up for 38 months during which time she sustained a branch retinal vein occlusion in her left eye. RESULTS/CONCLUSIONS:An asymmetric appearance to the crystalline deposition was not...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)72791-6

    authors: Chang TS,Aylward W,Clarkson JG,Gass JD

    更新日期:1995-06-01 00:00:00

  • Microkeratome-assisted mushroom keratoplasty with minimal endothelial replacement.

    abstract:PURPOSE:To report the outcome of a new keratoplasty technique aimed at treating full-thickness opacities with minimal removal of recipient endothelium. DESIGN:Interventional case report. METHODS:A deep central scar was removed using microkeratome-assisted mushroom-shaped keratoplasty, consisting of a large anterior s...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.12.024

    authors: Busin M,Arffa RC

    更新日期:2005-07-01 00:00:00

  • Nonaccommodative convergence excess.

    abstract::Nonaccommodative convergence excess is a condition in which a patient has orthotropia or a small-angle esophoria or esotropia at distance and a large-angle esotropia at near, not significantly reduced by the addition of spherical plus lenses. The AC/A ratio, determined with the gradient method, is normal or subnormal....

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(86)90466-6

    authors: von Noorden GK,Avilla CW

    更新日期:1986-01-15 00:00:00

  • Cystoid macular edema associated with ocular hypotensive lipids.

    abstract:PURPOSE:To report angiographically documented cystoid macula edema associated with the use of each of the three newly available ocular hypotensive lipids: unoprostone, travaprost, and bimatoprost. DESIGN:Observational case series. METHODS:Retrospective review of three patients in a clinical practice who had uncontrol...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(01)01411-8

    authors: Wand M,Gaudio AR

    更新日期:2002-03-01 00:00:00

  • Hyperopia as a risk factor for nonarteritic anterior ischemic optic neuropathy.

    abstract::The most convincing morphologic component in the pathogenesis of nonarteritic anterior ischemic optic neuropathy is the anatomically small and crowded optic nerve head. Because the appearance of the optic disk is presumed to be related to underlying refractive error, we sought to determine if a particular refractive e...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)73477-4

    authors: Katz B,Spencer WH

    更新日期:1993-12-15 00:00:00

  • Objective Evaluation of Corneal and Lens Clarity in Children With Type 1 Diabetes Mellitus.

    abstract:PURPOSE:To investigate whether abnormal glucose metabolism and duration of diabetes mellitus (DM) affected the corneal and lens clarity in children with well-controlled type 1 DM and to compare the results obtained with those in healthy children. DESIGN:Cross-sectional prospective study. METHODS:This multicenter stud...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ajo.2017.05.010

    authors: Tekin K,Inanc M,Kurnaz E,Bayramoglu E,Aydemir E,Koc M,Aycan Z

    更新日期:2017-07-01 00:00:00

  • Corneal higher-order aberrations induced by overnight orthokeratology.

    abstract:PURPOSE:To evaluate corneal higher-order aberrations induced by overnight orthokeratology for myopia. DESIGN:Prospective, noncomparative, consecutive, interventional case series. METHODS:A prospective study was conducted in 64 eyes of 39 patients with overnight orthokeratology for myopia, who were followed up for at ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.10.006

    authors: Hiraoka T,Matsumoto Y,Okamoto F,Yamaguchi T,Hirohara Y,Mihashi T,Oshika T

    更新日期:2005-03-01 00:00:00

  • Intensified Topical Steroids as Prophylaxis for Macular Edema After Posterior Lamellar Keratoplasty Combined With Cataract Surgery.

    abstract:PURPOSE:To analyze the effect of intensified topical steroid therapy after Descemet membrane endothelial keratoplasty combined with cataract surgery (triple-DMEK) on the incidence of postoperative cystoid macular edema (CME). DESIGN:Single-center comparative clinical study with historical controls. METHODS: SETTING:...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2015.12.008

    authors: Hoerster R,Stanzel TP,Bachmann BO,Siebelmann S,Felsch M,Cursiefen C

    更新日期:2016-03-01 00:00:00

  • Iris suture fixation of subluxated intraocular lenses.

    abstract:PURPOSE:To assess the results of iris suture fixation of subluxated intraocular lenses. DESIGN:Retrospective study. METHODS:This was a nonrandomized chart review of eyes with subluxated intraocular lenses that underwent iris suture fixation at an academic institutional care center. Seventy-two eyes of 67 consecutive ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2014.11.009

    authors: Soiberman U,Pan Q,Daoud Y,Murakami P,Stark WJ

    更新日期:2015-02-01 00:00:00

  • Photoreceptor oxidative damage in sympathetic ophthalmia.

    abstract:PURPOSE:To determine photoreceptor oxidative stress and damage in sympathetic ophthalmia (SO). DESIGN:Immunohistologic study. METHODS:Eight formalin-fixed and paraffin-embedded human globes with typical histologic features of SO and five age-matched globes without intraocular inflammation (controls) were retrieved fr...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2008.03.026

    authors: Parikh JG,Saraswathy S,Rao NA

    更新日期:2008-12-01 00:00:00

  • Late recurrence of retinal detachment following successful vitreous surgery for stages 4B and 5 retinopathy of prematurity.

    abstract:PURPOSE:To determine the incidence and possible causes of a late recurrence of a retinal detachment (RD) in eyes with stages 4B and 5 retinopathy of prematurity (ROP), in which the retina was once reattached by lensectomy and vitrectomy. DESIGN:Retrospective, comparative case series. METHODS:The medical records of 12...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2008.10.006

    authors: Kondo H,Arita N,Osato M,Hayashi H,Oshima K,Uchio E

    更新日期:2009-04-01 00:00:00

  • Traumatic chiasmal syndrome associated with pneumocephalus and sellar fracture.

    abstract::A 50-year-old man sustained severe head injury, including a brief loss of consciousness, in an automobile accident. Skull X-ray films disclosed a fracture of the right superior orbit. Computed tomography demonstrated pneumocephalus and extension of the fracture into the sella turcica. Perimetric testing disclosed a bi...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(81)90778-9

    authors: Resneck JD,Lederman IR

    更新日期:1981-08-01 00:00:00

  • Sudden retinal manifestations of intranasal cocaine and methamphetamine abuse.

    abstract::We examined two patients who had sudden decrease in vision after intranasal cocaine or methamphetamine abuse. A 38-year-old woman with a history of systemic arterial hypertension developed a central retinal artery occlusion four hours after intranasal use of cocaine. A 26-year-old woman had blurred vision and intraret...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)73979-0

    authors: Wallace RT,Brown GC,Benson W,Sivalingham A

    更新日期:1992-08-15 00:00:00

  • Laser photocoagulation for choroidal neovascularization associated with sympathetic ophthalmia.

    abstract:PURPOSE:To present a case of choroidal neovascularization associated with sympathetic ophthalmia successfully treated with photocoagulation. DESIGN:Interventional case report. METHODS:A 41-year-old man with a history of penetrating injury right eye, as well as sympathetic ophthalmia left eye, developed a classic chor...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(01)01044-3

    authors: Borkowski LM,Weinberg DV,Delany CM,Milsow L

    更新日期:2001-10-01 00:00:00

  • Safety and effectiveness of concomitant administration of dipivefrin and timolol maleate.

    abstract::Dipivefrin, an epinephrine prodromal drug, was used in conjunction with timolol maleate to evaluate the safety and effectiveness of combined therapy. Seventeen patients who had used timolol maleate for at least six months added dipivefrin (Group 1) and seven patients who had used dipivefrin for at least six months add...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(81)90182-3

    authors: Keates EU,Stone RA

    更新日期:1981-02-01 00:00:00