Abstract:
:We compared the intraocular pressure-decreasing effect of timolol maleate alone, acetazolamide alone, and combined timolol and acetazolamide therapy in nine patients with bilateral chronic open-angle glaucoma. Timolol decreased intraocular pressure at least as effectively as acetazolamide. The two medications together were more effective than either medication alone, but they did not have a fully additive effect. Episcleral venous pressures and outflow facilities did not vary significantly with any of the three treatment regimens.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Berson FG,Epstein DLdoi
10.1016/s0002-9394(14)75631-4subject
Has Abstractpub_date
1981-12-01 00:00:00pages
788-91issue
6eissn
0002-9394issn
1879-1891pii
S0002-9394(14)75631-4journal_volume
92pub_type
杂志文章abstract:PURPOSE:To evaluate corneal higher-order aberrations induced by overnight orthokeratology for myopia. DESIGN:Prospective, noncomparative, consecutive, interventional case series. METHODS:A prospective study was conducted in 64 eyes of 39 patients with overnight orthokeratology for myopia, who were followed up for at ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.10.006
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:The Drusen Laser Study evaluated macular laser to prevent choroidal neovascularization (CNV) and vision loss in high-risk age-related maculopathy (ARM). DESIGN:Prospective, interventional, randomized, controlled clinical trial in five hospital centers. METHODS:Patients in the unilateral group had neovascular ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2005.08.019
更新日期:2006-02-01 00:00:00
abstract::A 32-year-old obese woman with hypertension and a three-year history of pseudotumor cerebri developed bilateral juxtapapillary subretinal neovascular membranes. To our knowledge, this is the first reported case of bilateral subretinal neovascular membranes complicating the course of this disease. The subretinal neovas...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90282-8
更新日期:1981-03-01 00:00:00
abstract:PURPOSE:To study the glistening formation in various hydrophobic-acrylic intraocular lens (IOL) models, and to evaluate the effect of glistenings on light scattering in these IOLs. DESIGN:Laboratory investigation. METHODS:The susceptibility of the hydrophobic-acrylic material to develop glistenings was evaluated in 6...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.08.032
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To evaluate the outcomes of epiretinal membrane (ERM) surgery in highly myopic eyes without traction maculopathy, and to compare them with those from non-highly myopic eyes. DESIGN:Retrospective nested case-control study from a cohort of 509 consecutive patients (509 eyes) who underwent pars plana vitrectomy w...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.03.035
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:Anterior segment optical coherence tomography (AS-OCT) provides an objective imaging modality for visually identifying anterior segment structures. An automated detection system could assist ophthalmologists in interpreting AS-OCT images for the presence of angle closure. DESIGN:Development of an artificial in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2019.02.028
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:To assess the efficacy and safety of adjunctive daunorubicin during vitrectomy surgery in eyes with idiopathic proliferative vitreoretinopathy (PVR). METHODS:Two hundred eighty-six eyes (286 patients) with stage C2 (Retina Society Classification, 1983) or more advanced preoperative PVR in which surgery with si...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(98)00115-9
更新日期:1998-10-01 00:00:00
abstract:PURPOSE:To examine the usefulness of fluorescein angiography (FA) in identifying the macular center and diagnosis of zone in patients with retinopathy of prematurity (ROP). DESIGN:Validity and reliability analysis of diagnostic tools. METHODS:Thirty-two sets (16 color fundus photographs and 16 color fundus photograph...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.01.027
更新日期:2015-05-01 00:00:00
abstract::The pathogenesis of reversible cupping of the optic disk in congenital glaucoma was examined by two approaches. Human fetal, neonatal, and adult eyes were examined by histochemistry and electron microscopy to delineate the embryologic development of the optic nerve head. While the neural, glial, and vascular elements ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(77)90680-8
更新日期:1977-09-01 00:00:00
abstract::In August 1989, the Tokyo Metropolitan Government officially began a vision screening program for children aged 3 years 1 month. A 1988 pilot study of 1,303 children this age disclosed five cases (0.38%) of amblyopia. The home vision test, which uses picture cards of familiar figures, proved to be an efficient and ine...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71851-3
更新日期:1992-10-15 00:00:00
abstract:PURPOSE:To perform a quantitative trait locus (QTL) analysis and evaluate whether a locus between SIX1 and SIX6 is associated with retinal nerve fiber layer (RNFL) thickness in individuals of European descent. DESIGN:Observational, multicenter, cross-sectional study. METHODS:A total of 231 participants were recruited...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2015.04.001
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:To determine the safety of pars plana vitrectomy in eyes containing a treated posterior uveal melanoma. DESIGN:Interventional case series. METHODS:Retrospective case series of patients with posterior uveal melanoma who underwent pars plana vitrectomy. Complications, vitreous cytology, local tumor control, and...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00244-7
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:To determine whether cataract in patients with atopic dermatitis is associated with higher levels of aqueous flare or cells. METHODS:In a prospective study, 35 consecutive patients examined during a 6-month period at the atopic dermatitis service in a university hospital underwent standardized ophthalmologic e...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71641-1
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:To perform a cross-sectional study on the distribution of central corneal thickness and its association with intraocular pressure in an elderly population. METHODS:We measured central corneal thickness and intraocular pressure in 395 subjects (352 control subjects, 13 patients with ocular hypertension, and 30 ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71125-0
更新日期:1997-06-01 00:00:00
abstract::We examined two eyes from two noninsulin-dependent diabetic patients that developed vitreous hemorrhage secondary to retinal neovascularization after branch retinal arterial obstruction. Although there was no ophthalmoscopic evidence of diabetic retinopathy, diabetes mellitus may have predisposed the retinas to a neov...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(87)90420-x
更新日期:1987-09-15 00:00:00
abstract:PURPOSE:Progressive change in optic disk appearance has been suggested as the best available reference standard for glaucoma diagnosis. We evaluated the accuracy of scanning laser polarimetry (SLP) with variable corneal compensation to discriminate patients with documented progressive optic disk change from healthy sub...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.01.003
更新日期:2005-06-01 00:00:00
abstract::A retrospective study of patients who underwent keratoplasty for keratoconus was done in 100 consecutive cases, of which 50 were penetrating keratoplasty procedures, and 50 were lamellar keratoplasty procedures. Each case was done by the same surgeon in both series. Criteria for patient selection were essentially the ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(78)90126-5
更新日期:1978-12-01 00:00:00
abstract::We used scanning electron microscopy to study the surfaces of five coated soft contact lenses from subjects with giant papillary conjunctivitis. Findings were compared to the surfaces of five coated lenses from normal, asymptomatic wearers and five new, nerver-worn lenses. Lenses were from various manufacturers. All w...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90416-1
更新日期:1979-12-01 00:00:00
abstract:PURPOSE:To compare choroidal vascularity index (CVI) in patients with arteritic anterior ischemic optic neuropathy (A-AION), nonarteritic anterior ischemic optic neuropathy (NA-AION), and control subjects. DESIGN:Retrospective cross-sectional study. METHODS:This study was conducted at the Ophthalmology Unit of the S....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.03.028
更新日期:2019-09-01 00:00:00
abstract::Benign lateral rectus palsy developed in two adults, a 62-year-old man and a 56-year-old woman. Both were hospitalized because of headache and diplopia. Extensive laboratory and neurologic testing showed no abnormalities except leukopenia (the white blood cell count was 2,600 cells/mm3 in one patient and 3,100 cells/m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(82)90254-9
更新日期:1982-10-01 00:00:00
abstract:PURPOSE:To report corneal histopathology associated with keratectasia after laser in situ keratomileusis (LASIK) and to evaluate the thickness of the calculated residual stromal bed in two cases and those in the literature. DESIGN:Interventional case reports. METHODS:Three eyes of two patients developed keratectasia ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01656-2
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:We sought to assess the effects of exposure to secondhand smoke (SHS) on peripapillary retinal nerve fiber layer (p-RNFL) thickness in children. DESIGN:Cross-sectional study. METHODS:Children 6-8 years of age were consecutively recruited from the population-based Hong Kong Children Eye Study. All participants...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.10.016
更新日期:2020-10-29 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the baseline features associated with blindness in a cohort of children with primary congenital glaucoma (PCG) from a hospital registry. METHODS:Setting: Observational cohort study DESIGN: Retrospective clinical cohort study STUDY POPULATION: The registry included all chil...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.014
更新日期:2020-12-21 00:00:00
abstract::Of 42 patients studied who had fundus flavimaculatus and Stargardt's disease, most had reduced visual acuity due to an atrophic macular lesion. Family histories were consistent with autosomal-recessive inheritance. In some young patients, the yellow-white flecks developed with time, while in some older patients the fl...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90539-0
更新日期:1976-10-01 00:00:00
abstract::Nonaccommodative convergence excess is a condition in which a patient has orthotropia or a small-angle esophoria or esotropia at distance and a large-angle esotropia at near, not significantly reduced by the addition of spherical plus lenses. The AC/A ratio, determined with the gradient method, is normal or subnormal....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90466-6
更新日期:1986-01-15 00:00:00
abstract:PURPOSE:To evaluate postkeratoplasty astigmatism between two suture techniques 2 to 4 years postoperatively in a group of patients previously studied 9 months postoperatively. METHODS:Thirty-two patients who underwent penetrating keratoplasty were randomly assigned to one of two groups. Group 1 (16 patients) had a 24-...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(14)70489-1
更新日期:1996-11-01 00:00:00
abstract::The original (1969) classification of the Eye Changes of Graves' Disease has been retained except for Classes 1 and 3. Class 1 has been limited so that proptosis of 23 mm or greater is placed in Class 3, even if the patient is asymptomatic. Grading of Classes 1 and 2 has been left to the individual physician or clinic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(77)90140-4
更新日期:1977-05-01 00:00:00
abstract:PURPOSE:To determine the haptic position in transsclerally sutured posterior chamber lenses. METHODS:Fifty eyes with transsclerally sutured posterior chamber lenses were evaluated gonioscopically to determine the superior haptic position using previous peripheral iridectomies. RESULTS:The superior haptic of the trans...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70146-1
更新日期:1997-03-01 00:00:00
abstract:PURPOSE:To report a patient with uveal effusion and intermittent angle-closure glaucoma associated with primary pulmonary hypertension. METHODS:Observational case report. RESULTS:A 78-year-old woman with primary pulmonary hypertension noticed pain and decreased vision in her right eye. Ocular examination disclosed ex...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)02090-1
更新日期:2003-05-01 00:00:00
abstract::We studied the clinical and histopathologic ocular findings in four related males with a newly recognized syndrome consisting of microphthalmos, microencephaly, mental retardation, agenesis of the corpus callosum, hypospadius, and cryptorchidism with X-linked recessive inheritance. The ocular abnormalities include mic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75866-0
更新日期:1985-01-15 00:00:00