Abstract：
:Of 150 consecutive cases of preretinal macular fibrosis that occurred predominantly in older subjects, 118 cases involved only one eye while 32 occurred binocularly. The ratio of women to men was 3:2. Visual acuity was usually 20/50 or better, and only four of 178 eyes had acuity below 20/200. The vast majority of lesions involved the macula and few extended outside the macular zone. The characteristic clinical finding on ophthalmoscopy was a glinting reflex probably due to a layer of connective tissue cells lying on the internal limiting membrane. Small white exudates, venous abnormalities, and occasional hemorrhages may also be part of prepretinal macular fibrosis. Amsler grid testing usually demonstrated irregularity and distortion of some part of the grid. Fluorescein angiography revealed a characteristic tortuosity of the small macular vessels. Most eyes had previous posterior vitreous detachments but, except for one possible case, there were no cases where the posterior vitreous body was adherent to either the retinal membrane or the macular region. There was no significant systemic disease related to preretinal macular fibrosis. In most instances, preretinal macular fibrosis either was stationary or slowly progressive. The etiology and treatment of the condition remains obscure.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Wise GNdoi
10.1016/0002-9394(75)90605-4subject
Has Abstractpub_date
1975-03-01 00:00:00pages
349-7issue
3eissn
0002-9394issn
1879-1891pii
0002-9394(75)90605-4journal_volume
79pub_type
杂志文章abstract：PURPOSE:To assess the risks of vitrectomy for the removal of primary and secondary vitreous opacities. DESIGN:Retrospective, nonrandomized, interventional case series. METHODS:We reviewed the results of 116 consecutive cases of vitrectomy for vitreous floaters. Eighty-six cases were primary and 30 cases were secondar...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.01.005
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:To explore the impact of intracameral air tamponade pressure and duration on graft attachment and rebubbling rates. DESIGN:A prospective, interventional, nonrandomized study. METHODS:setting: Department of Ophthalmology, Charité - Universitätsmedizin Berlin. STUDY POPULATION:One hundred seventeen patients wh...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.03.021
更新日期：2017-06-01 00:00:00
abstract：:A countrywide prevalence survey of 9,508 children was conducted in El Salvador to determine the prevalence of anterior-segment abnormalities and magnitude of clinical vitamin A deficiency. Thirty-six children had corneal opacities, 56% of them secondary to trauma. Such traumatic corneal opacities were 19 times more fr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90337-2
更新日期：1975-12-01 00:00:00
abstract：PURPOSE:To identify factors related to graft rejection following Descemet stripping automated endothelial keratoplasty (DSAEK) in the Cornea Preservation Time Study (CPTS). DESIGN:Cohort study within a multicenter randomized clinical trial. METHODS:A total of 1330 eyes of 1090 subjects undergoing DSAEK were randomize...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ajo.2018.10.005
更新日期：2018-12-01 00:00:00
abstract：:We evaluated the reliability of optic disk area and disk rim area measurements obtained with the Humphrey Retinal Analyzer from ten repeat fundus images each of one eye of ten normal subjects and ten subjects with increased intraocular pressure. Variability of rim and disk areas was not significantly different between...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73309-4
更新日期：1989-10-15 00:00:00
abstract：PURPOSE:Autosomal recessive congenital fibrosis of the extraocular muscles (CFEOM2) has been described in families from Saudi Arabia. Affected individuals have ptosis and exotropic ophthalmoplegia, and their disease has been mapped to chromosome 11q13. Here, we describe the phenotypic findings in a similarly affected Y...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00467-5
更新日期：2000-05-01 00:00:00
abstract：PURPOSE:To evaluate the repeatability of an extensive number of relevant indices with the Pentacam HR in keratoconus of varying severity and normal eyes. DESIGN:Reliability analysis. METHODS:This study was performed at Antwerp University Hospital, Belgium, and enrolled 20 healthy volunteers (20 eyes) and 69 patients ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.06.013
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:To use micro-ribonucleic acid (microRNA) profiles in the vitreous for differential diagnosis of primary vitreoretinal lymphoma and uveitis. DESIGN:Prospective cross-sectional study. METHODS:This prospective cross-sectional study included 17 diffuse large B-cell primary vitreoretinal lymphoma and 12 uveitis pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.12.014
更新日期：2014-03-01 00:00:00
abstract：:In this prospective evaluation of the reliability and efficiency of an optimized visual field screening protocol for glaucoma, we tested 145 eyes (73 patients) with increased intraocular pressures to determine the location of early glaucomatous visual field defects. The field examination, which was used as a control, ...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：
更新日期：1981-10-01 00:00:00
abstract：PURPOSE:To compare the prevalence of keratoconjunctivitis sicca (KCS) in a prospective cohort of 22,382 diabetic patients with that in the general population. DESIGN:Prospective, observational, cohort study. METHODS: SETTING:A district of israel's largest health maintenance organization. STUDY POPULATION:We followe...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.10.022
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:Intraindividual comparison of tilt and decentration of three-piece foldable intraocular lenses (IOLs) with 6-mm optics and different edge design and material. DESIGN:Prospective randomized study. METHODS:Twenty-five patients with senile cataract (group I) received a foldable silicone, sharp optic edge IOL in ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ajo.2005.07.026
更新日期：2005-12-01 00:00:00
abstract：PURPOSE:To report a patient with persistent subepithelial corneal opacities 18 months after adenoviral keratoconjunctivitis who underwent photorefractive keratectomy for the correction of myopia. METHODS:Case report, review of medical literature, and slit-lamp photography. RESULTS:The patient underwent photorefractiv...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00224-4
更新日期：1998-12-01 00:00:00
abstract：PURPOSE:To reexamine the role of the vitreous gel in ocular health and disease based on recent information in the ophthalmic literature. DESIGN:Perspective. METHODS:Review, analysis, and discussion of the implications of selected pertinent literature. RESULTS:A new understanding of the vitreous gel is emerging, plac...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ajo.2009.07.036
更新日期：2010-01-01 00:00:00
abstract：PURPOSE:To report dry eye patients' functional visual acuity, which was measured after sustained eye opening for 10-20 seconds, as a simulation of visual function of daily acts of gazing, which is defined as looking at an object with involuntary blink suppression. METHODS:Interventional clinical nonrandomized comparat...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/s0002-9394(01)01365-4
更新日期：2002-02-01 00:00:00
abstract：:We observed a 41-year-old man with congenital unilateral iris pigment epithelial hyperplasia associated with unilateral glaucoma, and considered the possible pathogenesis of this unique lesion and its relationship to the patient's glaucoma. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76809-6
更新日期：1978-08-01 00:00:00
abstract：PURPOSE:To investigate the frequency and types of systemic findings in patients with apparently isolated uveal coloboma. DESIGN:Cross-sectional observational study. METHODS:setting: Single-center ophthalmic genetics clinic. study population: Ninety-nine patients with uveal coloboma seen at the National Eye Institute....
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.06.037
更新日期：2013-12-01 00:00:00
abstract：:Study of a father and son who had helicoid peripapillary chorioretinal degeneration suggests that a progressive tearing and retraction of the retinal pigment epithelium or of Bruch's membrane around the optic disk may be involved in the disorder's pathogenesis. We presume that this tearing results primarily from dyspl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74552-0
更新日期：1990-03-15 00:00:00
abstract：:A patient who used contact lenses and had a history of blunt trauma developed vaccinia keratouveitis after accidental ocular autoinoculation from a recent vaccination site. Corneal and conjunctival cultures were taken for bacteria, fungi, Acanthamoeba, and viruses. Viral-like cytopathic effects became evident in tissu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70008-x
更新日期：1994-04-15 00:00:00
abstract：PURPOSE:To determine the relationship between delayed patchy choroidal filling and morphologic and functional outcomes among eyes treated with ranibizumab or bevacizumab. DESIGN:Cohort study. METHODS:Comparison of Age-related Macular Degeneration Treatment Trials participants were assigned randomly to ranibizumab or ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ajo.2014.06.004
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:To report a case of bilateral acute retinal necrosis caused by cytomegalovirus. METHODS:A diagnostic vitrectomy was performed on a patient with non-Hodgkin lymphoma who presented with a bilateral, rapidly progressing necrotizing retinitis and uveitis. RESULTS:Immunohistochemical studies and polymerase chain r...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00250-5
更新日期：1999-01-01 00:00:00
abstract：:We measured the magnitude and time course of the increase in palpebral fissure width in ten normal volunteers in response to direct-acting (2.5% phenylephrine, 1% apraclonidine) and indirect-acting (10% cocaine, 1% hydroxyamphetamine) topical adrenergic drugs given in one eye. The increase in the palpebral fissure wid...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76775-3
更新日期：1991-06-15 00:00:00
abstract：:A 5-month-old infant girl died of familial lymphohistiocytosis. The central nervous system showed widespread perivascular infiltration of the cerebral pia and arachnoid, the cerebral white matter and deep gray matter, the cerebellum, and brain stem by lymphocytes, benign appearing histiocytes, and macrophages with ery...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90013-1
更新日期：1976-11-01 00:00:00
abstract：:Corneas for penetrating keratoplasty that have been excised from the globe for storage ordinarily require punching of the donor tissue from the posterior surface. They may be trephined from the anterior surface when they are mounted on an instrument that forms a seal around the scleral rim of the excised cornea, allow...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90021-0
更新日期：1976-11-01 00:00:00
abstract：PURPOSE:We previously demonstrated that selective suture removal reduces keratoplasty astigmatism; however, a myopic shift was induced with the increasing number of interrupted sutures removed. This study is an attempt to determine the effects of a modified surgical technique on postkeratoplasty myopia, astigmatism, an...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)02287-0
更新日期：2003-06-01 00:00:00
abstract：:Visual loss secondary to vitreous hemorrhage or retinal detachment can occur in proliferative sickle retinopathy. Severe complications including a high incidence of anterior segment necrosis have been reported in both vitrectomy and scleral buckling operations in patients with this disease. We examined four patients w...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(87)90004-3
更新日期：1987-08-15 00:00:00
abstract：PURPOSE:To determine the type of herpes simplex virus in acute retinal necrosis syndrome associated with herpes simplex virus. METHODS:Herpes simplex virus type 1, herpes simplex virus type 2, varicella-zoster virus, Epstein-Barr virus, and cytomegalovirus were examined by polymerase chain reaction in intraocular spec...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00391-8
更新日期：2000-03-01 00:00:00
abstract：:The noninvasive laser Doppler technique was used to study retinal circulatory characteristics in five patients who underwent uncomplicated scleral buckling procedures. In each patient, the systolic/diastolic variation of the red blood cell speed in the retinal arteries (flow pulsatility ratio) was lower in the eye tha...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(83)90012-0
更新日期：1983-02-01 00:00:00
abstract：:Using the Cochet-Bonnet esthesiometer, we evaluated the corneal sensation of 11 patients with unilateral Adie's tonic pupil. We eliminated six other patients with bilateral Adie's pupil or disease that lowered corneal sensation. An observed unfamiliar with each patient's condition tested 12 clock hour positions in the...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/0002-9394(77)90440-8
更新日期：1977-10-01 00:00:00
abstract：:Retinal tacks that can be easily placed and removed allow precise intraocular control of retinal fixation in the repair of complicated retinal detachments. We used this technique in 41 consecutive cases of complicated retinal detachment. In 37 cases follow-up was six months or more. We achieved reattachment of the pos...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90203-5
更新日期：1986-07-15 00:00:00
abstract：PURPOSE:To report a case of chronic recurrent varicella virus epithelial keratitis in a child. DESIGN:Case report. METHODS:Clinical examination and polymerase chain reaction analysis of corneal epithelium. RESULTS:A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.12.014
更新日期：2005-06-01 00:00:00
