Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing.

Abstract:

PURPOSE:To report a case of chronic recurrent varicella virus epithelial keratitis in a child. DESIGN:Case report. METHODS:Clinical examination and polymerase chain reaction analysis of corneal epithelium. RESULTS:A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites after recovering from systemic varicella. Analysis of the debrided pseudodendrites was repeatedly positive for VZV DNA and negative for HSV DNA. Treatment with oral acyclovir and topical corticosteroid drops was effective in eliminating the pseudodendrites; however, recurrences occurred once the medications were discontinued. CONCLUSIONS:Varicella virus epithelial keratitis in children can be a recurrent chronic condition requiring prolonged treatment.

journal_name

Am J Ophthalmol

authors

Magone MT,Nasser RE,Cevallos AV,Margolis TP

doi

10.1016/j.ajo.2004.12.014

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

1135-6

issue

6

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(04)01495-3

journal_volume

139

pub_type

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