Abstract:
PURPOSE:To compare the late complications in the Ahmed Baerveldt Comparison Study during 5 years of follow-up. DESIGN:Multicenter, prospective randomized clinical trial. METHODS:setting: Sixteen international clinical centers. STUDY POPULATION:Two hundred seventy-six subjects aged 18-85 years with previous intraocular surgery or refractory glaucoma with intraocular pressure of >18 mm Hg. INTERVENTIONS:Ahmed Glaucoma Valve FP7 or Baerveldt Glaucoma Implant BG 101-350. MAIN OUTCOME MEASURES:Late postoperative complications (beyond 3 months), reoperations for complications, and decreased vision from complications. RESULTS:Late complications developed in 56 subjects (46.8 ± 4.8 5-year cumulative % ± SE) in the Ahmed Glaucoma Valve group and 67 (56.3 ± 4.7 5-year cumulative % ± SE) in the Baerveldt Glaucoma Implant group (P = .082). The cumulative rates of serious complications were 15.9% and 24.7% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .034), although this was largely driven by subjects who had tube occlusions in the 2 groups (0.8% in the Ahmed Glaucoma Valve group and 5.7% in the Baerveldt Glaucoma Implant group, P = .037). Both groups had a relatively high incidence of persistent diplopia (12%) and corneal edema (20%), although half of the corneal edema cases were likely due to pre-existing causes other than the aqueous shunt. The incidence of tube erosion was 1% and 3% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .04). CONCLUSIONS:Long-term rates of vision-threatening complications and complications resulting in reoperation were higher in the Baerveldt Glaucoma Implant than in the Ahmed Glaucoma Valve group over 5 years of follow-up.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Budenz DL,Feuer WJ,Barton K,Schiffman J,Costa VP,Godfrey DG,Buys YM,Ahmed Baerveldt Comparison Study Group.doi
10.1016/j.ajo.2015.11.023subject
Has Abstractpub_date
2016-03-01 00:00:00pages
75-82.e3eissn
0002-9394issn
1879-1891pii
S0002-9394(15)00711-4journal_volume
163pub_type
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