Abstract:
PURPOSE:To assess the effect of Ahmed glaucoma valve implants on corneal endothelial cell density (ECD) in children with uveitic glaucoma. DESIGN:Cross-sectional study. METHODS:setting: Institutional. patientpopulation: Eighty eyes from 42 patients diagnosed with uveitis before the age of 16. Twenty-eight eyes had an Ahmed glaucoma valve implant because of secondary glaucoma. Fifty-two eyes without an implant served as controls. intervention orobservationprocedure(s): Corneal ECD was examined cross-sectionally using a noncontact specular microscope. Univariate and multivariate generalized estimating equations analyses with correction for paired eyes were performed. mainoutcomemeasure(s): Correlation of ECD with the presence of an Ahmed glaucoma valve implant and with the time following implantation. RESULTS:ECD was significantly lower in the Ahmed glaucoma valve group than in controls (2359 and 3088 cells/mm(2), respectively; P < .001) following an average of 3.5 years after Ahmed glaucoma valve implantation. Presence of an Ahmed glaucoma valve implant, previous intraocular surgery, age, duration of uveitis, and history of corneal touch by the implant tube were all significantly associated with decreased ECD. Following a multivariate analysis, presence of an Ahmed glaucoma valve implant (B = -340; adjusted P < .011) and older age (B = -58; adjusted P = .005) remained independently associated with decreased ECD. Within the implant group, the age-adjusted time interval following Ahmed glaucoma valve implantation was highly correlated with decreased ECD (B = -558, P < .001). CONCLUSIONS:Ahmed glaucoma valve implants in children with uveitic glaucoma are independently associated with decreased ECD, and this effect is associated with the time interval following Ahmed glaucoma valve implantation.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Kalinina Ayuso V,Scheerlinck LM,de Boer JHdoi
10.1016/j.ajo.2012.09.001subject
Has Abstractpub_date
2013-03-01 00:00:00pages
530-5issue
3eissn
0002-9394issn
1879-1891pii
S0002-9394(12)00615-0journal_volume
155pub_type
杂志文章abstract:PURPOSE:To evaluate the repeatability of an extensive number of relevant indices with the Pentacam HR in keratoconus of varying severity and normal eyes. DESIGN:Reliability analysis. METHODS:This study was performed at Antwerp University Hospital, Belgium, and enrolled 20 healthy volunteers (20 eyes) and 69 patients ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.06.013
更新日期:2020-11-01 00:00:00
abstract::We performed a histologic study to support our clinical observations on the mechanisms responsible for traction retinal detachment after a penetrating injury in the rhesus monkey eye. The monkey eyes (40 eyes; 40 monkeys) were characterized by intraocular fibrosis with the formation of a cyclitic membrane and epiretin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90469-0
更新日期:1979-08-01 00:00:00
abstract:PURPOSE:To assess the safety of rAAV.sFlt-1 subretinal injection in neovascular age-related macular degeneration (wet AMD) over 36 months. DESIGN:Phase 1 dose escalation trial. METHODS:Eight subjects with advanced, treatment-experienced wet AMD were randomly assigned (3:1) to treatment and non-gene therapy control gr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
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更新日期:2017-05-01 00:00:00
abstract::A 46-year old woman and a 59-year-old man had corneal crystals, multiple myeloma, and IgG kappa hypergammaglobulinemia. In one case, crystalline deposits were also present in the lens. In both patients there was a marked decrease in the amount of crystals during chemotherapy. The crystals within the cornea of one case...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1978-09-01 00:00:00
abstract:PURPOSE:To report bilateral optic disk edema and blindness as the unusual initial presentation of acute lymphocytic leukemia (ALL) in an adult. METHODS:A 19-year-old man presented with a history of headaches, back pain, and 10 days of worsening vision that progressed to blindness. Ocular examination revealed light per...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01465-4
更新日期:2002-07-01 00:00:00
abstract:PURPOSE:To determine the incidence of developing an idiopathic full-thickness macular hole in fellow eyes that have vitreofoveal attachments and perifoveal vitreous detachment in patients with unilateral idiopathic macular hole. DESIGN:Retrospective cross-sectional observational study. METHODS:The fellow eyes of 201 ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.03.070
更新日期:2005-09-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2017-04-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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更新日期:2007-10-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:1997-08-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2006-08-01 00:00:00
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更新日期:2004-04-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2002-09-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-12-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:American journal of ophthalmology
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更新日期:2009-04-01 00:00:00
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更新日期:1998-09-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2010-04-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2006-07-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1979-08-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1981-03-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1993-03-15 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2004-10-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2012-04-01 00:00:00