Abstract：
:A 46-year old woman and a 59-year-old man had corneal crystals, multiple myeloma, and IgG kappa hypergammaglobulinemia. In one case, crystalline deposits were also present in the lens. In both patients there was a marked decrease in the amount of crystals during chemotherapy. The crystals within the cornea of one case were identified by light and electron microscopy in material obtained during a lamellar keratoplasty. The crystalline deposits were located only in the corneal epithelium, and their regular repeating internal arrangement was confirmed by monochromatic optical diffraction of electron micrographs of sections through them. By immunofluorescent and immunoperoxidase techniques, the crystals reacted positively for immunoglobulin and particularly IgG kappa chains.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Klintworth GK,Bredehoeft SJ,Reed JWdoi
10.1016/0002-9394(78)90230-1subject
Has Abstractpub_date
1978-09-01 00:00:00pages
303-13issue
3eissn
0002-9394issn
1879-1891pii
0002-9394(78)90230-1journal_volume
86pub_type
杂志文章abstract：:Fifteen patients with malignant epithelial tumors of the conjunctiva were treated with beta-ray ocular applicators filled with radioactive strontium and yttrium (90Sr/90Y). Histologic examination confirmed the diagnosis. There were ten squamous cell carcinomas, four carcinomas in situ, and one case of epidermidalizati...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0002-9394(76)90731-5
更新日期：1976-02-01 00:00:00
abstract：PURPOSE/METHODS:Central retinal artery occlusion occurs infrequently in children. We treated a child with central retinal artery occlusion before a systemic disease was discovered. RESULTS/CONCLUSION:Vision improved after paracentesis and anticoagulation. Systemic T-cell lymphoma was subsequently diagnosed. In contras...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73772-9
更新日期：1995-07-01 00:00:00
abstract：PURPOSE:To investigate visual function and optical quality in eyes with epiphora undergoing lacrimal passage intubation. DESIGN:Prospective case series. METHODS:Thirty-four eyes of 30 patients with lacrimal passage obstruction were enrolled. Before and 1 month after lacrimal passage intubation, functional visual acui...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.06.022
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:To determine whether eyestrain symptoms predict eye conditions in 6-year-old children. DESIGN:Cross-sectional population-based study. METHODS:Reports of eyestrain symptoms were sought in parental questionnaires; 1740 children (79% response) underwent eye examinations (visual acuity, cover testing, cycloplegic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2006.03.047
更新日期：2006-09-01 00:00:00
abstract：:Eleven patients with intracranial malignant neoplasms underwent hyperosmotic opening of the blood-brain barrier by rapid mannitol infusion via the internal carotid or vertebral artery. Cyclophosphamide was administered intravenously preceding the mannitol infusion and methotrexate was infused after the mannitol via th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90536-2
更新日期：1986-11-15 00:00:00
abstract：PURPOSE:To describe a modified laser technique for identification of bullous retinoschisis. DESIGN:Retrospective interventional case series collected over 10 years. METHODS:Forty-one eyes with presumed bullous retinoschisis and breaks in the inner layers underwent a low-energy argon green laser application at the sam...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00485-9
更新日期：2003-11-01 00:00:00
abstract：:To study further the transient increase in trabecular cell division within the first two days after laser trabeculoplasty in human corneoscleral explant organ cultures, we used a pulse-chase protocol in which immediately after laser treatment 3H-thymidine was added to the culture medium for 48 hours (the pulse period)...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90805-2
更新日期：1989-01-15 00:00:00
abstract：PURPOSE:To report the clinical settings, microbiological isolates, and best-corrected visual acuities (BCVA) of patients with persistently culture-positive exogenous fungal endophthlamitis. DESIGN:Retrospective consecutive case series. METHODS:Setting: Tertiary referral center. PATIENT POPULATION:Sixteen eyes of 16 ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.09.014
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To investigate in open-angle glaucoma the focal macular photopic negative response and spectral-domain optical coherence tomography measurements of retinal thicknesses in the superior and inferior macula. DESIGN:Comparative case series. METHODS:We studied 63 eyes of 63 patients with open-angle glaucoma and 41...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.09.018
更新日期：2011-03-01 00:00:00
abstract：:Four patients (three men, 68, 35, and 33 years old, and one woman, 46 years old) had central serous elevation of the macula with abnormal latency of the visual-evoked potential and spontaneous Pulfrich phenomenon. In three instances both the electrophysiologic test and the clinical Pulfrich test reverted to normal on ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90684-1
更新日期：1985-10-15 00:00:00
abstract：PURPOSE:To determine whether spectral-domain optical coherence tomography (SD-OCT) disorganization of the retinal inner layers (DRIL) is predictive of best-corrected visual acuity (BCVA) in retinal vein occlusion macular edema (RVO-ME). DESIGN:Retrospective cohort study. METHODS:Setting: Two tertiary centers. PATIEN...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2017.08.005
更新日期：2017-10-01 00:00:00
abstract：:Of a series of 57 formerly amblyopic patients who attained equal visual acuities (20/20 or better in each eye), only 29 were able to alternate after treatment. The oldest patient was 5 years old. The pattern visual-evoked response of the previously amblyopic eye in nonalternators showed a reduced amplitude as compared...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75868-4
更新日期：1985-01-15 00:00:00
abstract：PURPOSE:To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis. DESIGN:Retrospective cohort study. METHODS:Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.12.042
更新日期：2004-06-01 00:00:00
abstract：PURPOSE:To report the clinical outcomes of penetrating keratoplasty (PK) after autologous cultivated limbal epithelial transplantation in eyes with limbal stem cell deficiency (LSCD) after ocular surface burns. DESIGN:Retrospective case series. METHODS:This study included 47 patients with unilateral LSCD treated by a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.05.019
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:To describe the clinical and histopathologic findings in a patient with Parinaud's oculoglandular syndrome attributable to Francisella tularensis obtained from an encounter with a wild baby rabbit. METHODS:In an 18-year-old man, the clinical course, laboratory findings, and histopathologic findings are describ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00954-5
更新日期：2001-02-01 00:00:00
abstract：:In August 1989, the Tokyo Metropolitan Government officially began a vision screening program for children aged 3 years 1 month. A 1988 pilot study of 1,303 children this age disclosed five cases (0.38%) of amblyopia. The home vision test, which uses picture cards of familiar figures, proved to be an efficient and ine...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71851-3
更新日期：1992-10-15 00:00:00
abstract：PURPOSE:We present two cases with early macular holes (MH) complicated by retinoschisis and foveal detachment (RSFD). DESIGN:Case reports. CASE REPORT:A 46-year-old woman and a 70-year-old woman, both with high myopia, presented visual loss and a small MH associated with RSFD. Vitrectomy and gas tamponade were perfor...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00319-2
更新日期：2003-10-01 00:00:00
abstract：PURPOSE:The effectiveness of diffusion trace value analysis for non-invasive assessment of retinal ganglion cell (RGC) axonal degeneration at multiple anatomic levels along the human visual pathway under clinical setting was evaluated. DESIGN:Imaging study. METHODS:Ten patients with unilateral chronic optic neuropath...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.05.042
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:To review the contributions to ophthalmic genetics through the American Journal of Ophthalmology (AJO). DESIGN:Perspective. METHODS:A literature search to retrieve original articles, letters, editorials, and published lectures from 1966 to 2017, providing a 50-year review. Titles were excluded that gave no re...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ajo.2018.03.004
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To compare the prevalence of keratoconjunctivitis sicca (KCS) in a prospective cohort of 22,382 diabetic patients with that in the general population. DESIGN:Prospective, observational, cohort study. METHODS: SETTING:A district of israel's largest health maintenance organization. STUDY POPULATION:We followe...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.10.022
更新日期：2005-03-01 00:00:00
abstract：:Two patients had paresis of the trochlear nerve contralateral to the site of lesions in the brainstem. Both patients had ipsilateral blepharoptosis and miosis suggesting oculosympathetic paresis from involvement of the descending sympathetic tract, adjacent to the fourth cranial nerve nucleus and its fascicles, in the...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90818-0
更新日期：1989-01-15 00:00:00
abstract：PURPOSE:To report an unusual case of orbital floor implant migration across the ethmoidal sinuses and nasal septum. METHOD:Case report. A 61-year-old woman with a history of right orbital floor fracture repair 25 years earlier is described. RESULTS:The patient presented with sinus congestion and difficulty breathing ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00239-6
更新日期：1998-12-01 00:00:00
abstract：:Of 76 members of a large pedigree with familial aniridia, 61% of the 38 affected patients had visual acuity of 6/9 (20/30) or better and only 5% had acuity of 6/60 (20/200) or worse. Cataracts were present in 18% of affected patients; glaucoma in 13%; and strabismus in 34%. Sixteen percent of affected patients had str...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90139-8
更新日期：1977-05-01 00:00:00
abstract：PURPOSE:To observe longitudinal changes in the corneal endothelium after pediatric cataract surgery with intraocular lens implantation. DESIGN:Prospective, longitudinal study. METHODS:settings: Iladevi Cataract and IOL Research Centre, Ahmedabad, India. study population: This study included 100 pediatric eyes undergo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.02.018
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:To present a large series of choroidal hemangiomas treated with proton beam irradiation and to describe the treatment outcomes. METHODS:We treated 54 eyes of 53 patients with choroidal hemangioma. The lesions consisted of 48 circumscribed hemangiomas and six diffuse hemangiomas in patients with Sturge-Weber sy...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00150-0
更新日期：1998-08-01 00:00:00
abstract：PURPOSE:To evaluate the mechanism of spontaneous resolution of foveal detachments and idiopathic macular breaks. METHODS:We reviewed the records of 139 consecutive eyes (94 patients) with either a foveal detachment or a macular break in patients who were examined between 1989 and 1992. There were 26 men and 68 women (...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72730-8
更新日期：1995-12-01 00:00:00
abstract：PURPOSE:To identify a rapid and reliable method to detect the Glutamine 368 STOP (Q368STOP) disease-predisposing allele of the myocilin gene associated with adult onset, primary, open-angle glaucoma. METHODS:Individuals with the Q368STOP mutation of the myocilin gene were identified from a cohort of primary open-angle...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00812-6
更新日期：2001-04-01 00:00:00
abstract：PURPOSE:To evaluate the ocular biometric parameters associated with intraocular pressure (IOP) reduction after phacoemulsification. DESIGN:Prospective, observational case series. METHODS:The study included 999 patients who had undergone uncomplicated phacoemulsification. IOP and ocular biometric parameters were check...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.02.003
更新日期：2013-07-01 00:00:00
abstract：:We studied the ultrastructural characteristics of 23 vascularized preretinal membranes removed from 22 eyes during pars plana vitrectomy for proliferative diabetic retinopathy. Traction detachment of the macula was the most frequent reason for surgery (15 of 22 eyes), followed by nonclearing vitreous hemorrhage (seven...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90240-1
更新日期：1988-05-15 00:00:00
abstract：:Two patients with massive epithelium-lined inclusion cysts of the orbit became symptomatic five and 16 years after scleral buckling. Each patient described diplopia and displacement of the previously treated eye. An orbitotomy in the first patient disclosed a loculated epithelium-lined inclusion cyst that extended pos...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76169-0
更新日期：1992-04-15 00:00:00
