Abstract:
PURPOSE:To clarify the clinical characteristics of reticular pseudodrusen in Korean patients. DESIGN:Retrospective, observational, consecutive case series. METHODS:A total of 255 eyes of 130 patients diagnosed with reticular pseudodrusen were evaluated. Reticular pseudodrusen were diagnosed by characteristic fundus findings using ophthalmoscopy, color fundus photography with blue-channel examination, near-infrared photography, red-free photography, autofluorescence imaging, fluorescein angiography, indocyanine green angiography, and spectral-domain optical coherence tomography. Age-related macular degeneration (AMD) was determined by the International Classification and Grading System. RESULTS:The mean age was 72.6 ± 9.0 years (range, 43 to 92 years). Most reticular pseudodrusen patients had bilateral disease (97.7%), with a female preponderance (86.2%). All 3 patients who showed unilateral reticular pseudodrusen had neovascular AMD in the eye with no reticular pseudodrusen. AMD was found in 183 eyes (71.8 %), among which early AMD was found in 115 eyes (45.1%), geographic atrophy was found in 41 eyes (16.1%), and neovascular AMD was found in 27 eyes (10.6%). The mean age of patients with AMD and with no AMD was 73.7 ± 9.2 years (range, 58 to 92 years) and 69.9 ± 11.7 years (range, 43 to 90 years), respectively, and there was a statistical difference between these 2 groups (P < .05). Classic choroidal neovascularization was found in 13 eyes (48.1%), and occult choroidal neovascularization was found in 14 eyes (51.9%) in the neovascular AMD group. CONCLUSIONS:Reticular pseudodrusen occurs in Koreans, and clinical manifestations of reticular pseudodrusen in Koreans did not differ significantly from those described in white persons. However, our study demonstrated a higher rate of bilaterality compared with those previously reported, and geographic atrophy was found to be associated more commonly with reticular pseudodrusen than with neovascular AMD. Ethnical differences may be associated with these findings, and further studies are required.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Lee MY,Yoon J,Ham DIdoi
10.1016/j.ajo.2011.08.012subject
Has Abstractpub_date
2012-03-01 00:00:00pages
530-5issue
3eissn
0002-9394issn
1879-1891pii
S0002-9394(11)00637-4journal_volume
153pub_type
杂志文章abstract::Twelve patients (14 eyes) had intraocular pressure elevations induced by repository coritcosteroids. The duration and severity of the resulting pressure elevations were directly related to the decreasing solubility of the agent employed. Ten patitens had received intensive topical corticosteroids before injection, res...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90669-3
更新日期:1976-07-01 00:00:00
abstract:PURPOSE:To determine the 24-month results of patients who had pro re nata (PRN) aflibercept treatment owing to recurrent or resistant neovascular macular degeneration. DESIGN:Retrospective, interventional, consecutive case series. METHODS:Eighty-one eyes of 78 patients with resistant or multiple recurrences of intrar...
journal_title:American journal of ophthalmology
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更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To evaluate the long-term outcomes of laser in situ keratomileusis (LASIK) for high myopia. DESIGN:A long-term (10 years) follow-up retrospective interventional case series study. METHODS:The study included 196 myopic eyes of 118 patients with a mean preoperative spherical equivalent of -13.95 +/- 2.79 diopte...
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abstract::A graft of hard palate mucosa is a satisfactory substitute for the posterior lamella of tarsus and conjunctiva in eyelid reconstruction. The graft may be harvested after administration of local anesthesia in adults, provides structural support as well as a mucosal surface, and contracts minimally. The palatal donor si...
journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
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更新日期:2004-05-01 00:00:00
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更新日期:1984-02-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.08.035
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:To evaluate low- vs high-dose plaque brachytherapy for juxtapapillary choroidal melanoma. DESIGN:Retrospective interventional case series. METHODS:Setting: Single institution. STUDY POPULATION:Forty-seven patients with juxtapapillary choroidal melanoma. INTERVENTION:Iodine-125 plaque brachytherapy. Eyes wer...
journal_title:American journal of ophthalmology
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更新日期:2018-02-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(78)90239-8
更新日期:1978-09-01 00:00:00
abstract:PURPOSE:Immune checkpoint inhibitors (ICI) targeting the programmed cell death protein 1 (PD-1), or its ligand PD-L1, are the mainstay of metastatic cancer treatment. Patients receiving these treatments may develop immune-related adverse events (irAEs). This study aimed to estimate the prevalence and describe the clini...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.11.043
更新日期:2007-04-01 00:00:00
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journal_title:American journal of ophthalmology
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doi:10.1016/j.ajo.2013.03.035
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To report rapidly progressive rhino-orbitocerebral mucormycosis in a 47-year-old woman with both diabetes mellitus and the acquired immunodeficiency syndrome (AIDS). METHOD:Case report including postmortem examination of the eyes, orbit, and brain of a patient with rhino-orbitocerebral mucormycosis, diabetes m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70392-7
更新日期:1996-12-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2017-07-01 00:00:00
abstract:PURPOSE:To report a rare case of craniodiaphysial dysplasia (CDD) that resulted in a profound loss of vision in both eyes. DESIGN:Observational case report. METHODS:A 2-year-old girl presented with midfacial anomaly. Marked thickening and sclerosis in the calvaria and facial bones were detected on the plain x-rays, w...
journal_title:American journal of ophthalmology
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更新日期:2006-02-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ajo.2005.03.061
更新日期:2005-10-01 00:00:00
abstract::Using immunohistochemical techniques, we studied ligneous conjunctival lesions from two patients. A significant immune reaction was detected that was characterized by activated T lymphocytes and focal accumulation of plasma cells and B lymphocytes. Immunofluorescent studies demonstrated that IgG was a prominent compon...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1989-02-15 00:00:00
abstract::Subconjunctival 5-fluorouracil has been an effective adjunct in glaucoma filtering surgery. We investigated the effectiveness of 5-fluorouracil in primary trabeculectomy combined with phacoemulsification and posterior chamber intraocular lens implantation (glaucoma triple procedure). Seventy-four patients were enrolle...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(14)73202-7
更新日期:1993-11-15 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2000-02-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2004-01-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)01196-5
更新日期:2002-01-01 00:00:00
abstract:PURPOSE/METHODS:Orthoclone OKT3 is a monoclonal murine IgG immunoglobulin used to treat acute cellular rejection of allografted organs. Aseptic meningitis and meningoencephalopathy are known adverse side effects from the drug. OKT3 caused additional ophthalmologic and neurologic complications in an 18-year-old woman wh...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70236-3
更新日期:1995-05-01 00:00:00
abstract::Two groups of patients, 37 with primary basal cell carcinoma of the eyelid and 16 with basal cell carcinoma of the eyelid previously treated by other physicians were reviewed. All of the tumors were excised with at least 3 to 4 mm of normal-appearing tissue at each margin of resection. All of the excised specimens wer...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90358-1
更新日期:1979-06-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2002-06-01 00:00:00