Abstract：
PURPOSE:We studied patients with chronic open-angle glaucoma who had similar intraocular pressures to determine whether surgical or medical therapy is more effective in preventing progressive, long-term, glaucomatous damage. METHODS:Included in this study were patients with chronic open-angle glaucoma who were followed for 3 years or longer and were treated, through either medical or surgical therapy, by adjusting intraocular pressure to 18 mm Hg or less as a therapeutic end point. We studied 31 matched pairs of patients in which one member was treated by surgery and one member had medical treatment. In every pair, we matched each patient individually by age, race, and intraocular pressure. RESULTS:For the matched pairs of patients in this study, the mean intraocular pressure following initiation of treatment was 13.5 and 13.1 mm Hg for the surgically and medically treated groups, respectively (P = .475). This study found no difference between groups in the incidence of glaucomatous progression following surgical (n = 3) or medical (n = 3) therapy (P > .99, McNemar's test) for an average follow-up of 40.0 +/- 10.0 and 43.4 +/- 8.4 months in the medical and surgical groups respectively. The glaucoma of three patients progressed on the basis of reduced visual acuity, two by visual field, and one by disk hemorrhage. Although the types of complications from therapy differed between groups, no vision loss or life-threatening events occurred directly from these treatments. CONCLUSIONS:When intraocular pressure is used as a therapeutic end point, both filtration surgery and medical therapy appear to be equally effective in maintaining long-term visual function and a stable optic disk in chronic open-angle glaucoma.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Stewart WC,Sine CS,LoPresto Cdoi
10.1016/s0002-9394(14)70372-1subject
Has Abstractpub_date
1996-12-01 00:00:00pages
767-74issue
6eissn
0002-9394issn
1879-1891pii
S0002-9394(14)70372-1journal_volume
122pub_type
杂志文章abstract：PURPOSE:A defect in the visual field is one of the serious complications of macular hole surgery. We investigated the relationship between the occurrence of visual field defect and the location of infusion cannula and air pressure during fluid-air exchange. METHODS:We studied 100 eyes from 90 patients with macular hol...
journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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更新日期：2007-07-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2003-10-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1978-02-01 00:00:00
abstract：PURPOSE/METHODS:We studied a case of crystalline retinopathy occurring after prolonged use of oral canthaxanthin. The patient was followed up for 38 months during which time she sustained a branch retinal vein occlusion in her left eye. RESULTS/CONCLUSIONS:An asymmetric appearance to the crystalline deposition was not...
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更新日期：1995-06-01 00:00:00
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更新日期：2003-08-01 00:00:00
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更新日期：2006-11-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1998-01-01 00:00:00
abstract：:A 17-year old girl received prednisone and azathioprine for the treatment of systemic lupus erythematosus. She developed a fever and hallucinations 18 months later; cryptococcal meningitis was diagnosed. An internal ophthalmoplegia with loss of accommodation and dilation of the pupils developed together with bilateral...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1979-05-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：1987-12-15 00:00:00
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pub_type： 杂志文章
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更新日期：2007-05-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
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更新日期：2017-05-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1988-02-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1991-08-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2010-11-01 00:00:00
abstract：:During a two-year period a randomly selected age-stratified sample of subjects 65 years old and older living in Gisborne, New Zealand, was examined by an ophthalmologist to investigate visual acuity and the prevalence of the major disorders of vision in old age. A total of 481 subjects (a response rate of 86.2%) compl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90073-3
更新日期：1982-08-01 00:00:00
abstract：PURPOSE:This study sought to investigate retinal function in patients with noninfectious uveitis by using full-field electroretinography (ERG) and correlate the ERG to disease duration and severity of inflammation. DESIGN:Prospective cohort study. METHODS:Patients (n = 200) with noninfectious uveitis and a disease du...
journal_title：American journal of ophthalmology
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更新日期：2019-11-01 00:00:00
