The Madurai Intraocular Lens Study. III: Visual functioning and quality of life outcomes.

Abstract:

PURPOSE:To compare the effects of extracapsular cataract extraction with posterior chamber intraocular lens (ECCE/PC-IOL) vs intracapsular cataract extraction with aphakic glasses (ICCE-AG) on everyday visual functioning and quality of life. METHODS:In a nonmasked randomized controlled clinical trial, 3,400 bilateral vision-impaired patients, aged 40 to 75 years, with operable cataract were randomly assigned to receive one of the two treatment options. One half in each group were randomly selected for interviewer administration of visual functioning and quality of life questionnaires before surgery and at 6 and 12 months after surgery. RESULTS:Both ICCE-AG and ECCE/PC-IOL produced dramatic improvements in visual functioning and quality of life scores. Patients receiving ECCE/PC-IOL reported larger beneficial changes than did those receiving ICCE-AG, compatible with additional beneficial effects of a moderate magnitude for visual functioning and of a smaller beneficial magnitude for quality of life. All between-group differences were highly statistically significant (P < .00001). The additional benefits of ECCE/PC-IOL are not explained by visual acuity differences. A higher proportion of patients in the ICCE-AG group reported problems on a vision problem checklist at 6 months (more than 50%) than did patients in the ECCE/PC-IOL group (approximately 30%). CONCLUSIONS:In this developing-country setting, ICCE-AG and ECCE/PC-IOL were associated with substantial benefits in improved everyday vision function and vision-related quality of life. Patients who received ECCE/PC-IOL reported greater benefits and fewer problems with vision than did patients who received ICCE-AG.

journal_name

Am J Ophthalmol

authors

Fletcher A,Vijaykumar V,Selvaraj S,Thulasiraj RD,Ellwein LB

doi

10.1016/s0002-9394(99)80231-1

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

26-35

issue

1

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(99)80231-1

journal_volume

125

pub_type

临床试验,杂志文章,随机对照试验
  • Bacteriologic profile of the conjunctiva in the patients with dry eye.

    abstract:PURPOSE:To assess the conjunctival bacterial profiles in dry eye and their fluoroquinolone susceptibility patterns. DESIGN:Prospective, observational study. METHODS:Sixty-seven female patients with dry eye (29 with Sjögren syndrome and 38 without Sjögren syndrome) who received artificial tears were enrolled at Osaka ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2008.06.003

    authors: Hori Y,Maeda N,Sakamoto M,Koh S,Inoue T,Tano Y

    更新日期:2008-11-01 00:00:00

  • Automated Pupillometry Using a Prototype Binocular Optical Coherence Tomography System.

    abstract:PURPOSE:To determine the test-retest reliability and diagnostic accuracy of a binocular optical coherence tomography (OCT) prototype (Envision Diagnostics, El Segundo, California, USA) for pupillometry. DESIGN:Assessment of diagnostic reliability and accuracy. METHODS:Fifty participants with relative afferent pupilla...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2020.02.013

    authors: Chopra R,Mulholland PJ,Petzold A,Ogunbowale L,Gazzard G,Bremner FD,Anderson RS,Keane PA

    更新日期:2020-06-01 00:00:00

  • Intraocular pressure elevation after intravitreal triamcinolone acetonide injection in a Chinese population.

    abstract:PURPOSE:To study the prevalence and risk factors of intraocular pressure (IOP) elevation and refractory IOP elevation after a single 4 mg intravitreal triamcinolone acetonide (IVTA) injection in a Chinese population. DESIGN:Retrospective, observational case series. METHODS:Retrospective chart review of all the patien...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2008.05.034

    authors: Lau LI,Chen KC,Lee FL,Chen SJ,Ko YC,Liu CJ,Hsu WM

    更新日期:2008-10-01 00:00:00

  • Characteristics of rhegmatogenous retinal detachment after refractive surgery: comparison with myopic eyes with retinal detachment.

    abstract:PURPOSE:To evaluate the characteristics of rhegmatogenous retinal detachment (RD) in patients with previous laser in situ keratomileusis (LASIK) and compare them to RD in patients with previous laser assisted subepithelial keratomileusis (LASEK) and myopic patients with no previous refractive surgery. DESIGN:Retrospec...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2013.12.004

    authors: Kang HM,Lee CS,Park HJ,Lee KH,Byeon SH,Koh HJ,Lee SC

    更新日期:2014-03-01 00:00:00

  • Transpupillary thermotherapy for subfoveal neovascularization secondary to group 2A idiopathic juxtafoveolar telangiectasis.

    abstract:PURPOSE:To evaluate the efficacy and safety of transpupillary thermotherapy (TTT) for subfoveal neovascularization (SRNVM) in patients with group 2A Idiopathic Juxtafoveolar Telangiectasis (IJFT). DESIGN:Nonrandomized interventional case series. METHODS:We performed TTT for subfoveal SRNVM in 14 eyes of 13 patients w...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.01.047

    authors: Shukla D,Singh J,Kolluru CM,Kim R,Namperumalsamy P

    更新日期:2004-07-01 00:00:00

  • Total plasma homocysteine and primary open-angle glaucoma.

    abstract:PURPOSE:To evaluate total plasma homocysteine (tHcy) levels in patients diagnosed with primary open-angle glaucoma (POAG) and normal subjects. DESIGN:Case-control study. METHODS:This study involved 55 POAG patients, 16 patients with secondary open-angle glaucoma or angle-closure glaucoma (non-POAG group), and 39 cont...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2003.09.041

    authors: Wang G,Medeiros FA,Barshop BA,Weinreb RN

    更新日期:2004-03-01 00:00:00

  • Persistently Vitreous Culture-Positive Exogenous Fungal Endophthalmitis.

    abstract:PURPOSE:To report the clinical settings, microbiological isolates, and best-corrected visual acuities (BCVA) of patients with persistently culture-positive exogenous fungal endophthlamitis. DESIGN:Retrospective consecutive case series. METHODS:Setting: Tertiary referral center. PATIENT POPULATION:Sixteen eyes of 16 ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2016.09.014

    authors: Leung EH,Kuriyan AE,Flynn HW Jr,Relhan N,Huang LC,Miller D

    更新日期:2016-12-01 00:00:00

  • Macular edema in association with severe carotid artery obstruction.

    abstract::In seven eyes of six patients (four men and two women, 55 to 72 years old), with macular edema associated with severe carotid artery stenosis, the ipsilateral carotid obstruction was 90% or more. Concomitant fundus signs, such as midperipheral retinal hemorrhages, retinal arterial narrowing, and neovascularization of ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(86)90071-1

    authors: Brown GC

    更新日期:1986-10-15 00:00:00

  • Histological and physiological studies of cyclocryotherapy in primate and human eyes.

    abstract::In human and primate eyes treated with cyclocryotherapy, the epithelial and capillary elements of the ciliary processes were destroyed and replaced by fibroblast-like cells. The trabecular mesh-work and Schlemm's canal were histologically affected by cyclocryotherapy. Damage to the angle structures impaired aqueous ou...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(76)90009-x

    authors: Quigley HA

    更新日期:1976-11-01 00:00:00

  • American Journal of Ophthalmology Contributions to Ophthalmic Genetics.

    abstract:PURPOSE:To review the contributions to ophthalmic genetics through the American Journal of Ophthalmology (AJO). DESIGN:Perspective. METHODS:A literature search to retrieve original articles, letters, editorials, and published lectures from 1966 to 2017, providing a 50-year review. Titles were excluded that gave no re...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajo.2018.03.004

    authors: MacDonald IM,Sieving PC

    更新日期:2018-06-01 00:00:00

  • Complications of Cosmetic Artificial Iris Implantation and Post Explantation Outcomes.

    abstract:PURPOSE:To report complications of cosmetic artificial iris implantation and explantation outcomes. SETTING:Stein Eye Institute DESIGN: : Retrospective case series METHODS: : Review of medical records of 12 patients (24 eyes) who presented to us after being implanted with cosmetic artificial irises elsewhere. Data col...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2021.01.005

    authors: Ghaffari R,Aldave AJ,Al-Hashimi S,Miller KM

    更新日期:2021-01-22 00:00:00

  • One-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To report 1-year results of reduced-fluence photodynamic therapy (PDT) for polypoidal choroidal vasculopathy (PCV) in Japanese patients. DESIGN:Prospective interventional case series. METHODS:In the present study, 28 treatment-naïve eyes of 28 consecutive patients underwent PDT with a reduced laser fluence of...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2009.09.020

    authors: Yamashita A,Shiraga F,Shiragami C,Ono A,Tenkumo K

    更新日期:2010-03-01 00:00:00

  • Successful use of topical cysteamine formulated from the oral preparation in a child with keratopathy secondary to cystinosis.

    abstract:PURPOSE:To report the successful use of topical cysteamine formulated from the oral preparation in the treatment of severe photophobia from corneal crystal deposition in cystinosis. DESIGN:Interventional case report. METHODS:Retrospective chart review. RESULTS:An 8-year-old boy with nephropathic cystinosis was exper...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.05.005

    authors: Khan AO,Latimer B

    更新日期:2004-10-01 00:00:00

  • Uveal Melanoma in BAP1 Tumor Predisposition Syndrome: Estimation of Risk.

    abstract:PURPOSE:To estimate point prevalence of uveal melanoma in the patients with germline BAP1 pathogenic variant. DESIGN:Cohort study with risk assessment using Bayesian analysis. METHODS:The point prevalence estimate was obtained by Bayes's rule of reverse conditional probabilities. The probability of uveal melanoma giv...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2020.12.005

    authors: Singh N,Singh R,Bowen RC,Abdel-Rahman MH,Singh AD

    更新日期:2020-12-11 00:00:00

  • Recession of both horizontal recti muscles in Duane's retraction syndrome with elevation and depression of the adducted eye.

    abstract::Upshoot and downshoot of the adducted eye in Duane's retraction syndrome is thought to be caused by a bridle effect of the co-contracting horizontal recti muscles. A recession of both of these muscles transposes their insertions posteriorly in relation to the center of rotation of the globe, which reduces the bridle e...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)71796-9

    authors: von Noorden GK

    更新日期:1992-09-15 00:00:00

  • Acquired pit of the optic nerve: a risk factor for progression of glaucoma.

    abstract:PURPOSE:To examine acquired pit of the optic nerve as a risk factor for progression of glaucoma. METHODS:In a retrospective longitudinal study, 25 open-angle glaucoma patients with acquired pit of the optic nerve were compared with a group of 24 open-angle glaucoma patients without acquired pit of the optic nerve. The...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(99)80185-8

    authors: Ugurlu S,Weitzman M,Nduaguba C,Caprioli J

    更新日期:1998-04-01 00:00:00

  • Cystoid macular edema associated with ocular hypotensive lipids.

    abstract:PURPOSE:To report angiographically documented cystoid macula edema associated with the use of each of the three newly available ocular hypotensive lipids: unoprostone, travaprost, and bimatoprost. DESIGN:Observational case series. METHODS:Retrospective review of three patients in a clinical practice who had uncontrol...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(01)01411-8

    authors: Wand M,Gaudio AR

    更新日期:2002-03-01 00:00:00

  • Pseudotumor cerebri associated with corticosteroid withdrawal in inflammatory bowel disease.

    abstract::We treated two patients with Crohn's disease and one patient with ulcerative colitis who developed headache, papilledema, and intracranial hypertension (pseudotumor cerebri) during corticosteroid withdrawal. One had four separate episodes with corticosteroid withdrawal, which suggested a causal relationship. This asso...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)73145-9

    authors: Liu GT,Kay MD,Bienfang DC,Schatz NJ

    更新日期:1994-03-15 00:00:00

  • Conjunctival intraepithelial neoplasia presenting as corneal ulcer.

    abstract:PURPOSE:To report a case of conjunctival intraepithelial neoplasia presenting as corneal ulcer. METHOD:Case report of a 28-year-old man who presented with sudden onset of pain, redness, and watering in the right eye. Examination of right cornea revealed deep stromal infiltrate inferonasally. Adjacent to the infiltrate...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(99)00286-x

    authors: Sridhar MS,Honavar SG,Vemuganti G,Rao GN

    更新日期:2000-01-01 00:00:00

  • Reduced expression of the adherens junction protein cadherin-5 in a diabetic retina.

    abstract:PURPOSE:Transvascular leakage occurs in diabetic retinopathy. The tight junction proteins occludin and zonula occludens-1 (ZO-1) and adherens junction protein cadherin-5 are critical to the maintenance of endothelial barrier. We report a comparison of junction protein expression in the normal and diabetic retina. METH...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(99)00323-2

    authors: Davidson MK,Russ PK,Glick GG,Hoffman LH,Chang MS,Haselton FR

    更新日期:2000-02-01 00:00:00

  • Clinical benefits of the Boston Ocular Surface Prosthesis.

    abstract:PURPOSE:To evaluate the effects of the Boston Ocular Surface Prosthesis (Boston Foundation for Sight, Needham, Massachusetts, USA) on visual acuity (VA) and visual functioning in patients with severe corneal ectasia, irregular astigmatism, or ocular surface disease. DESIGN:Prospective, interventional case series. MET...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2009.07.037

    authors: Stason WB,Razavi M,Jacobs DS,Shepard DS,Suaya JA,Johns L,Rosenthal P

    更新日期:2010-01-01 00:00:00

  • The retina in type 5 hyperlipoproteinemia.

    abstract::Of two patients with type 5 hyperlipoproteinemia, one exhibited lipemia retinalis with multiple retinal hemorrhages and intraretinal lipid extravasations. Postmortem examination showed hemorrhages in the inner retinal layers and lipid deposits largely in the outer plexiform layer. Lipid within the walls of the retinal...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(76)90661-9

    authors: Kurz GH,Shakib M,Sohmer KK,Friedman AH

    更新日期:1976-07-01 00:00:00

  • Toxic effect of fluorouracil on the rabbit retina.

    abstract::We conducted electrophysiologic tests of the toxic effects of fluorouracil on 26 albino rabbit eyes. Fluorouracil concentrations of 10(-7) g/ml, 10(-6) g/ml, and 10(-5) g/ml produced no significant changes in the b-wave amplitudes of the electroretinogram. A concentration of 10(-4) g/ml, however, reduced the b-wave am...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)73422-1

    authors: Nao-i N,Honda Y

    更新日期:1983-11-01 00:00:00

  • Clinical assessment of long-term safety and efficacy of a widely implanted polyacrylic intraocular lens material.

    abstract:PURPOSE:To evaluate the long-term safety and efficacy, in a large series of patients, of polyacrylic intraocular lens implants 1 and 3 years after surgery, compared with polymethylmethacrylate intraocular lens implants. METHODS:This was a randomized, prospective study of 1,514 eyes of 1,202 patients that were examined...

    journal_title:American journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-9394(00)00490-6

    authors: Kobayashi H,Ikeda H,Imamura S,Kobayashi K,Mitsuma Y,Minami M,Ishida O,Hirose M,Kobayashi K

    更新日期:2000-09-01 00:00:00

  • Epiretinal membrane surgery outcomes in highly myopic eyes without traction maculopathy: long-term results of a case-control study.

    abstract:PURPOSE:To evaluate the outcomes of epiretinal membrane (ERM) surgery in highly myopic eyes without traction maculopathy, and to compare them with those from non-highly myopic eyes. DESIGN:Retrospective nested case-control study from a cohort of 509 consecutive patients (509 eyes) who underwent pars plana vitrectomy w...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2013.03.035

    authors: El Sanharawi M,Sandali O,Bonnel S,Laroche L,Monin C

    更新日期:2013-08-01 00:00:00

  • Cataract surgery with ciliary sulcus fixation of intraocular lenses in patients with uveitis.

    abstract:PURPOSE:To describe intentional placement of intraocular lens haptics in the ciliary sulcus of patients with uveitis who are at high risk for postoperative posterior synechiae and lens dislocation. METHODS:We reviewed our experience with 16 eyes of 12 patients with uveitis who underwent cataract surgery with ciliary s...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(99)00140-3

    authors: Holland GN,Van Horn SD,Margolis TP

    更新日期:1999-07-01 00:00:00

  • Delay to treatment and visual outcomes in patients treated with anti-vascular endothelial growth factor for age-related macular degeneration.

    abstract:PURPOSE:To investigate the potential influences that affect visual acuity (VA) outcome in a clinic-based cohort of age-related macular degeneration (AMD) patients undergoing anti-vascular endothelial growth factor (anti-VEGF) treatment for choroidal neovascularization. DESIGN:Prospective interventional case series. M...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2011.09.013

    authors: Lim JH,Wickremasinghe SS,Xie J,Chauhan DS,Baird PN,Robman LD,Hageman G,Guymer RH

    更新日期:2012-04-01 00:00:00

  • Microkeratome-assisted mushroom keratoplasty with minimal endothelial replacement.

    abstract:PURPOSE:To report the outcome of a new keratoplasty technique aimed at treating full-thickness opacities with minimal removal of recipient endothelium. DESIGN:Interventional case report. METHODS:A deep central scar was removed using microkeratome-assisted mushroom-shaped keratoplasty, consisting of a large anterior s...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.12.024

    authors: Busin M,Arffa RC

    更新日期:2005-07-01 00:00:00

  • Outcomes of outpatient fluid-gas exchange for open macular hole after vitrectomy.

    abstract:PURPOSE:To report the efficacy and safety of outpatient fluid-gas exchange for open macular hole after primary vitrectomy. DESIGN:Retrospective interventional case series. METHODS:setting: Institutional. patients: Thirty-six patients with primary failed closure or reopened holes after primary vitrectomy. intervention...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2013.03.031

    authors: Rao X,Wang NK,Chen YP,Hwang YS,Chuang LH,Liu IC,Chen KJ,Wu WC,Lai CC

    更新日期:2013-08-01 00:00:00

  • PACAP induces neurite outgrowth in cultured trigeminal ganglion cells and recovery of corneal sensitivity after flap surgery in rabbits.

    abstract:PURPOSE:To evaluate the ability of pituitary adenylate cyclase-activating polypeptide (PACAP) to induce growth of neuronal processes in cultured trigeminal ganglion cells, and to accelerate neurite outgrowth and recovery of corneal sensitivity after creation of a corneal flap in a rabbit model of laser-assisted in situ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2006.10.034

    authors: Fukiage C,Nakajima T,Takayama Y,Minagawa Y,Shearer TR,Azuma M

    更新日期:2007-02-01 00:00:00