Fluorescein angiography with an optimized filter combination.


:The transmission characteristics of a new filter combination for fluorescein angiography were selected on the basis of in vivo measurements of the excitation and emission spectra of fluorescein dye during its transit in the fundus. This combination of filters was characterized by separation of 530 nm between the spectral ranges of transmission of the excitation and barrier filters. In the standard filter combinations this separation is at about 495 nm. Compared to the standard filters, the new filters enhanced the film exposure for all sites of the fundus, especially for the macular area and choroidal fluorescence. There was an improvement in demonstration of the choroidal vasculature, especially in the macular area, and better visibility of retinal detail in the macular area, but a slight decrease in contrast of the retinal vessels outside the macular region. Improved visibility of the fundus for the observer and reduction of scattering in the ocular media of older subjects improved the overall quality of angiograms made with the new filters.


Am J Ophthalmol


Delori F,Ben-Sira I,Trempe C




Has Abstract


1976-10-01 00:00:00














  • The effect of prior trabeculectomy on refractive outcomes of cataract surgery.

    abstract:PURPOSE:To examine surgical and refractive outcomes of phacoemulsification with intraocular lens (IOL) implant in eyes with prior trabeculectomy. DESIGN:Retrospective observational case-control study. METHODS:The study compared eyes that underwent phacoemulsification with IOL implant at least 3 months post-trabeculec...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Zhang N,Tsai PL,Catoira-Boyle YP,Morgan LS,Hoop JS,Cantor LB,WuDunn D

    更新日期:2013-05-01 00:00:00

  • Relationship between visual field testing and scanning laser polarimetry in patients with a large cup-to-disk ratio.

    abstract:PURPOSE:To determine the relationship between quantitative nerve fiber layer measurements and visual field testing in patients with large cup-to-disk ratios. METHODS:Seventy-six patients with vertical cup-to-disk ratios by contour of at least 0.8 on stereoscopic photographs and 50 normal subjects were included. One ey...

    journal_title:American journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Tannenbaum DP,Zangwill LM,Bowd C,Sample PA,Weinreb RN

    更新日期:2001-10-01 00:00:00

  • Effect of glaucoma on corneal graft survival according to indication for penetrating keratoplasty.

    abstract:PURPOSE:To determine whether the risk of graft failure in patients with glaucoma is dependent on the indication for penetrating keratoplasty (PK). DESIGN:Retrospective cohort study. METHODS:All patients on the United Kingdom Transplant Registry undergoing their first PK over a 7-year period with at least 1 year of fo...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Stewart RM,Jones MN,Batterbury M,Tole D,Larkin DF,Kaye SB,NHSBT Ocular Tissue Advisory Group and Contributing Ophthalmologists (OTAG Audit Study 9).

    更新日期:2011-02-01 00:00:00

  • Toxoplasmosis transmitted to a newborn from the mother infected 20 years earlier.

    abstract:PURPOSE:To present a case of congenital toxoplasmosis in a newborn whose mother had a 20-year history of a chorioretinal macular scar and positive serology for toxoplasmosis. DESIGN/METHODS:Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newb...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Silveira C,Ferreira R,Muccioli C,Nussenblatt R,Belfort R Jr

    更新日期:2003-08-01 00:00:00

  • Histologic development of the human fovea from midgestation to maturity.

    abstract:PURPOSE:To describe the histologic development of the human central retina from fetal week (Fwk) 22 to 13 years. DESIGN:Retrospective observational case series. METHODS:Retinal layers and neuronal substructures were delineated on foveal sections of fixed tissue stained in azure II-methylene blue and on frozen section...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Hendrickson A,Possin D,Vajzovic L,Toth CA

    更新日期:2012-11-01 00:00:00

  • Peripheral retinal nonperfusion associated with chronic myeloid leukemia.

    abstract:PURPOSE:To report a case of peripheral retinal nonperfusion and chronic myeloid leukemia in a 23-year-old woman. DESIGN:Observational case report. METHODS:A complete ophthalmic and systemic evaluation was performed. RESULTS:Ophthalmic examination revealed peripheral retinal nonperfusion with retinal neovascularizati...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Nobacht S,Vandoninck KF,Deutman AF,Klevering BJ

    更新日期:2003-03-01 00:00:00

  • Influence of the extent of myopia on the progression of normal-tension glaucoma.

    abstract:PURPOSE:To evaluate the influence of the extent of myopia on the progression rate of normal-tension glaucoma (NTG). DESIGN:Retrospective, observational case series. METHODS:One hundred forty-three eyes of 143 patients with NTG who were treated from 1994 through 2006 and followed up with standard automated perimetry w...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Sohn SW,Song JS,Kee C

    更新日期:2010-05-01 00:00:00

  • Choroidal Vascular Changes in Arteritic and Nonarteritic Anterior Ischemic Optic Neuropathy.

    abstract:PURPOSE:To compare choroidal vascularity index (CVI) in patients with arteritic anterior ischemic optic neuropathy (A-AION), nonarteritic anterior ischemic optic neuropathy (NA-AION), and control subjects. DESIGN:Retrospective cross-sectional study. METHODS:This study was conducted at the Ophthalmology Unit of the S....

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Pellegrini M,Giannaccare G,Bernabei F,Moscardelli F,Schiavi C,Campos EC

    更新日期:2019-09-01 00:00:00

  • Histopathology of meibomian gland dysfunction.

    abstract::We conducted a histopathologic study of he meibomian glands of seven patients (all men, ranging in age from 58 to 83 years) who had severe or moderately severe meibomian dysfunction and who were undergoing ectropion or entropion repair. Abnormal features included signs of obstruction and dilatation of ducts, enlargeme...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Gutgesell VJ,Stern GA,Hood CI

    更新日期:1982-09-01 00:00:00

  • Development of Pediatric Eye Questionnaires for Children With Eye Conditions.

    abstract:PURPOSE:To develop patient-derived Pediatric Eye Questionnaires (PedEyeQ) to separately assess eye-related quality of life (ER-QOL) and functional vision in children with eye conditions. DESIGN:Questionnaire development study. METHODS:A total of 444 children (0 to <18 years old), across 10 diagnostic categories, were...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,多中心研究


    authors: Hatt SR,Leske DA,Castañeda YS,Wernimont SM,Liebermann L,Cheng-Patel CS,Birch EE,Holmes JM

    更新日期:2019-04-01 00:00:00

  • Corneal endothelial changes after excimer laser photorefractive keratectomy.

    abstract::We used specular microscopy to investigate corneal endothelial changes after excimer laser photorefractive keratectomy. Twenty patients (26 eyes) underwent photorefractive keratectomy for the correction of myopia. The central cornea endothelium of each eye was observed preoperatively and one month postoperatively. Six...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Amano S,Shimizu K

    更新日期:1993-12-15 00:00:00

  • Autosomal recessive pericentral pigmentary retinopathy.

    abstract::A brother and sister, born to consanguineous parents, had pigmentary retinopathy in a pericentral distribution. The retinopathy was noted in infancy when the siblings were examined for strabismus. The optic disks, maculae, and retinal vessels were normal. There was mild reduction in amplitude of both scotopic and phot...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Traboulsi EI,O'Neill JF,Maumenee IH

    更新日期:1988-11-15 00:00:00

  • Correlation of Intraoperative Optical Coherence Tomography of Crystalline Lens Diameter, Thickness and Volume with Biometry and Age.

    abstract:PURPOSE:To characterize crystalline lens dimensions derived from in-vivo spectral-domain optical coherence tomography (SD-OCT) and identify associations between these parameters, ocular biometry and age. METHODS:In this retrospective study, lens thickness (LT), lens diameter (LD) and lens volume (LV) were measured int...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Waring GO 4th,Chang DH,Rocha KM,Gouvea L,Penatti R

    更新日期:2020-12-29 00:00:00

  • High-frequency Doppler ultrasound examination of blood flow in the anterior segment of the eye.

    abstract:PURPOSE:To show that extending Doppler imaging into the high-frequency domain could allow detection and characterization of blood flow in small arterioles and capillaries. METHODS:A 40-MHz continuous wave Doppler system and a 60-MHz pulsed-wave Doppler system were constructed, tested, and used to examine the ciliary b...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Pavlin CJ,Christopher DA,Burns PN,Foster FS

    更新日期:1998-10-01 00:00:00

  • Ocular histopathology in multiple endocrine neoplasia type 2b.

    abstract::Multiple endocrine neoplasia type 2b is a syndrome, often familial, characterized by medullary carcinoma of the thyroid gland, pheochromocytoma, and many mucosal neuromas in patients who frequently have a marfanoid habitus. The ophthalmic findings are distinctive and include conjunctival and eyelid neuromas, keratocon...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Riley FC Jr,Robertson DM

    更新日期:1981-01-01 00:00:00

  • Hypothermia of 8 degrees C protects cultured retinal pigment epithelial cells and retinal ganglion cells against trypan blue toxicity.

    abstract:PURPOSE:To determine whether hypothermia of 8 degrees C can protect cultured human retinal pigment epithelial (ARPE-19) cells and rat retinal ganglion cells (RGC-5) against trypan blue (TB) toxicity. DESIGN:Laboratory investigation. METHODS:ARPE-19 cells and RGC-5 were exposed to balanced salt solution as controls, a...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Kunikata H,Abe T,Murata H,Sagara Y,Wakusawa R,Sato H,Yoshida M,Fuse N,Tamai M

    更新日期:2006-04-01 00:00:00

  • Regional practice patterns for retinal detachment repair in the United States.

    abstract:PURPOSE:To determine if there are variations in regional practice patterns for retinal detachment repair in the United States. DESIGN:Retrospective, noninterventional, cross-sectional study. METHODS:Year 2009 Medicare fee-for-service claims for retinal detachment repair were aggregated in 4 geographic regions and eva...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Hwang JC

    更新日期:2012-06-01 00:00:00

  • Sclerocornea associated with the Smith-Lemli-Opitz syndrome.

    abstract::A 2,000-g infant boy had many features of the Smith-Lemli-Opitz syndrome (prenatal growth deficiency and developmental retardation, microcephaly with unusual facies, hypospadias, and feeding difficulties) as well as sclerocornea. The association of this rare eye finding with this rare congenital syndrome is unique. Su...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Harbin RL,Katz JI,Frias JL,Rabinowicz IM,Kaufman HE

    更新日期:1977-07-01 00:00:00

  • Risk Factors for Secondary Glaucoma in Herpetic Anterior Uveitis.

    abstract:PURPOSE:To determine the incidence of elevated intraocular pressure (IOP) and secondary glaucoma in herpetic anterior uveitis (AU), owing to either herpes simplex or varicella zoster virus, by using the Standardization of Uveitis Nomenclature (SUN) criteria, and to identify risk factors for the development of glaucoma....

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Hoeksema L,Jansonius NM,Los LI

    更新日期:2017-09-01 00:00:00

  • Bilateral effects of long-term monocular timolol therapy.

    abstract::We studied the bilateral intraocular pressure lowering effect of long-term unilateral timolol maleate 0.5% in 30 patients in whom early primary open-angle glaucoma had recently been diagnosed. A significant intraocular pressure reduction was found in the untreated fellow eyes (21.9 mm Hg from 26.4 mm Hg at baseline) (...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Kwitko GM,Shin DH,Ahn BH,Hong YJ

    更新日期:1987-12-15 00:00:00

  • How Are Ocular Signs and Symptoms of Dry Eye Associated With Depression in Women With and Without Sjögren Syndrome?

    abstract:PURPOSE:To determine whether ocular phenotypic features of keratoconjunctivitis sicca (KCS) and/or participant-reported symptoms of dry eye disease are associated with depression in women participants enrolled in the Sjögren's International Collaborative Clinical Alliance (SICCA). DESIGN:Cross-sectional study. METHOD...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,多中心研究


    authors: Gonzales JA,Chou A,Rose-Nussbaumer JR,Bunya VY,Criswell LA,Shiboski CH,Lietman TM

    更新日期:2018-07-01 00:00:00

  • The Expanded Spectrum of Perifoveal Exudative Vascular Anomalous Complex.

    abstract:PURPOSE:To expand our understanding of the uncommon entity, referred to as perifoveal exudative vascular anomalous complex (PEVAC) by describing multimodal imaging findings, including optical coherence tomography angiography (OCT-A). DESIGN:Retrospective cohort study. METHODS:Patients diagnosed with PEVAC were identi...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,多中心研究


    authors: Sacconi R,Freund KB,Yannuzzi LA,Dolz-Marco R,Souied E,Capuano V,Semoun O,Phasukkijwatana N,Sarraf D,Carnevali A,Querques L,Bandello F,Querques G

    更新日期:2017-12-01 00:00:00

  • Tilt and decentration of three-piece foldable high-refractive silicone and hydrophobic acrylic intraocular lenses with 6-mm optics in an intraindividual comparison.

    abstract:PURPOSE:Intraindividual comparison of tilt and decentration of three-piece foldable intraocular lenses (IOLs) with 6-mm optics and different edge design and material. DESIGN:Prospective randomized study. METHODS:Twenty-five patients with senile cataract (group I) received a foldable silicone, sharp optic edge IOL in ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Baumeister M,Neidhardt B,Strobel J,Kohnen T

    更新日期:2005-12-01 00:00:00

  • Current practices in the management of ocular toxoplasmosis.

    abstract::To determine current practices in the management of ocular toxoplasmosis, 72 of 85 uveitis specialists (85%) in the American Uveitis Society completed a detailed questionnaire. Questions involved the indications for beginning treatment, choice of antiparasitic/antimicrobial agents, and experience with treatment of ocu...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Engstrom RE Jr,Holland GN,Nussenblatt RB,Jabs DA

    更新日期:1991-05-15 00:00:00

  • One- Versus Two-Muscle Surgery for Presumed Unilateral Fourth Nerve Palsy Associated With Moderate Angle Hyperdeviations.

    abstract:PURPOSE:To compare 1-muscle vs 2-muscle surgery for moderate-angle hyperdeviations owing to presumed unilateral fourth nerve palsy. DESIGN:Retrospective chart review. METHODS:Seventy-three patients (aged 5-86 years) underwent either 1- or 2-muscle surgery at our institution for moderate hyperdeviation owing to presum...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Nash DL,Hatt SR,Leske DA,May L,Bothun ED,Mohney BG,Brodsky MC,Holmes JM

    更新日期:2017-10-01 00:00:00

  • A prospective study of the ophthalmologic findings in the acquired immune deficiency syndrome in Africa.

    abstract::A prospective study of ophthalmologic findings in 20 African patients with the acquired immunodeficiency syndrome (Group 1) and nine patients with acquired immune deficiency syndrome related complex (Group 2) disclosed that 11 patients in Group 1 and two patients in Group 2 had ocular involvement. Cotton-wool spots, R...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Kestelyn P,Van de Perre P,Rouvroy D,Lepage P,Bogaerts J,Nzaramba D,Clumeck N

    更新日期:1985-08-15 00:00:00

  • The Border of Macular Atrophy in Age-Related Macular Degeneration: A Clinicopathologic Correlation.

    abstract:PURPOSE:To correlate in vivo imaging to histology in an eye with macular atrophy owing to age-related macular degeneration (AMD; complete retinal pigment epithelium [RPE] and outer retinal atrophy [cRORA]) to evaluate the utility of new optical coherence tomography (OCT) suggested by previous histology. DESIGN:Case st...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Dolz-Marco R,Balaratnasingam C,Messinger JD,Li M,Ferrara D,Freund KB,Curcio CA

    更新日期:2018-09-01 00:00:00

  • Apneic spells associated with timolol therapy in a neonate.

    abstract::A 2-week-old premature child with congenital glaucoma secondary to anterior cleavage syndrome was treated with timolol maleate and cyclocryotherapy. The patient had apneic spells of up to 30 seconds that stopped soon after timolol maleate therapy was discontinued. No apnea was seen before timolol maleate administratio...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Olson RJ,Bromberg BB,Zimmerman TJ

    更新日期:1979-07-01 00:00:00

  • Gene Therapy in Neovascular Age-related Macular Degeneration: Three-Year Follow-up of a Phase 1 Randomized Dose Escalation Trial.

    abstract:PURPOSE:To assess the safety of rAAV.sFlt-1 subretinal injection in neovascular age-related macular degeneration (wet AMD) over 36 months. DESIGN:Phase 1 dose escalation trial. METHODS:Eight subjects with advanced, treatment-experienced wet AMD were randomly assigned (3:1) to treatment and non-gene therapy control gr...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,随机对照试验


    authors: Constable IJ,Lai CM,Magno AL,French MA,Barone SB,Schwartz SD,Blumenkranz MS,Degli-Esposti MA,Rakoczy EP

    更新日期:2017-05-01 00:00:00

  • Assessment of axonal degeneration along the human visual pathway using diffusion trace analysis.

    abstract:PURPOSE:The effectiveness of diffusion trace value analysis for non-invasive assessment of retinal ganglion cell (RGC) axonal degeneration at multiple anatomic levels along the human visual pathway under clinical setting was evaluated. DESIGN:Imaging study. METHODS:Ten patients with unilateral chronic optic neuropath...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章


    authors: Ueki S,Fujii Y,Matsuzawa H,Takagi M,Abe H,Kwee IL,Nakada T

    更新日期:2006-10-01 00:00:00